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892-21-7,MFCD00085494
Catalog No.:AA0044JN

892-21-7 | 3-Nitrofluoranthene

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100mg
technical grade, 90%
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1g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0044JN
Chemical Name:
3-Nitrofluoranthene
CAS Number:
892-21-7
Molecular Formula:
C16H9NO2
Molecular Weight:
247.2482
MDL Number:
MFCD00085494
SMILES:
[O-][N+](=O)c1ccc2c3c1cccc3c1c2cccc1
NSC Number:
57468
Properties
Computed Properties
 
Complexity:
377  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
4.7  

Downstream Synthesis Route

[1]Haeringen,C.J.van;Aten,N.F.;Cornelisse,J.;Lugtenburg,J.[RecueildesTravauxChimiquesdesPays-Bas,1992,vol.111,#7/8,p.335-344]

[2]v.Braun;Manz[JustusLiebigsAnnalenderChemie,1931,vol.488,p.111,115,116][JustusLiebigsAnnalenderChemie,1932,vol.496,p.170,191]

[3]Kloetzeletal.[JournaloftheAmericanChemicalSociety,1956,vol.78,p.1165,1167]

[4]Buu-Hoi,N.P.etal.[JournaloftheChemicalSociety,1964,p.3920-3924]

[5]Burmistrov,S.I.etal.[JournalofOrganicChemistryUSSR(EnglishTranslation),1965,vol.1,p.909-911][ZhurnalOrganicheskoiKhimii,1965,vol.1,#5,p.904-906]

[6]Ball,L.M.;Stocking,L.M.;Kohan,M.J.;Warren,S.H.;Lewtas,J.[Mutagenesis,1995,vol.10,#6,p.497-504]

[7]Locationinpatent:schemeortablePandarus,Valerica;Ciriminna,Rosaria;Beland,Francois;Pagliaro,Mario[AdvancedSynthesisandCatalysis,2011,vol.353,#8,p.1306-1316]

[8]Okazaki,Takao;Adachi,Taisuke;Kitagawa,Toshikazu[BulletinoftheChemicalSocietyofJapan,2013,vol.86,#4,p.464-471]

Literature

Title: Airborne nitro-PAHs induce Nrf2/ARE defense system against oxidative stress and promote inflammatory process by activating PI3K/Akt pathway in A549 cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA 20171001

Title: Mechanistic Investigations Into the Developmental Toxicity of Nitrated and Heterocyclic PAHs.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170501

Title: Health and cellular impacts of air pollutants: from cytoprotection to cytotoxicity.

Journal: Biochemistry research international 20120101

Title: The use of silver solid amalgam electrodes for voltammetric and amperometric determination of nitrated polyaromatic compounds used as markers of incomplete combustion.

Journal: TheScientificWorldJournal 20120101

Title: Oxidative stress and air pollution exposure.

Journal: Journal of toxicology 20110101

Title: Multivariate QSAR study on the antimutagenic activity of flavonoids against 3-NFA on Salmonella typhimurium TA98.

Journal: European journal of medicinal chemistry 20101001

Title: Differential effects of nitro-PAHs and amino-PAHs on cytokine and chemokine responses in human bronchial epithelial BEAS-2B cells.

Journal: Toxicology and applied pharmacology 20100201

Title: 1-Nitropyrene stabilizes the mRNA of cytochrome P450 1a1, a carcinogen-metabolizing enzyme, via the Akt pathway.

Journal: Chemical research in toxicology 20091201

Title: Signalling pathways involved in 1-nitropyrene (1-NP)-induced and 3-nitrofluoranthene (3-NF)-induced cell death in Hepa1c1c7 cells.

Journal: Mutagenesis 20091101

Title: 3-nitrofluoranthene (3-NF)-induced apoptosis and programmed necrosis.

Journal: Autophagy 20090701

Title: 3-Nitrofluoranthene (3-NF) but not 3-aminofluoranthene (3-AF) elicits apoptosis as well as programmed necrosis in Hepa1c1c7 cells.

Journal: Toxicology 20090131

Title: Absorption of nitro-polycyclic aromatic hydrocarbons by biomembrane models: effect of the medium lipophilicity.

Journal: Chemosphere 20081001

Title: Singlet excited-state dynamics of nitropolycyclic aromatic hydrocarbons: direct measurements by femtosecond fluorescence up-conversion.

Journal: The journal of physical chemistry. A 20070201

Title: Prediction of estrogen receptor agonists and characterization of associated molecular descriptors by statistical learning methods.

Journal: Journal of molecular graphics & modelling 20061101

Title: Mutagenic activities and physicochemical properties of selected nitrobenzanthrones.

Journal: Mutagenesis 20061101

Title: A combined chemical and bioassay analysis of traffic-emitted polycyclic aromatic hydrocarbons.

Journal: The Science of the total environment 20041201

Title: Derivatised carbon powder electrodes: reagentless pH sensors.

Journal: Talanta 20040708

Title: Induction of CYP1A1, CYP1A2, and CYP1B1 mRNAs by nitropolycyclic aromatic hydrocarbons in various human tissue-derived cells: chemical-, cytochrome P450 isoform-, and cell-specific differences.

Journal: Archives of toxicology 20020601

Title: Catechins are not major components responsible for anti-genotoxic effects of tea extracts against nitroarenes.

Journal: Mutation research 20010920

Title: Porphyrins with exocyclic rings. 16. Synthesis and spectroscopic characterization of fluoranthoporphyrins, a new class of highly conjugated porphyrin chromophores.

Journal: The Journal of organic chemistry 20010504

Title: Photodegradation of nitro-PAHs in viscous organic media used as models of organic aerosols.

Journal: Environmental science & technology 20010101

Title: Bioactivation of diesel exhaust particle extracts and their major nitrated polycyclic aromatic hydrocarbon components, 1-nitropyrene and dinitropyrenes, by human cytochromes P450 1A1, 1A2, and 1B1.

Journal: Mutation research 20001220

Title: Nitration of carcinogenic and non-carcinogenic polycyclic aromatic hydrocarbons results in products able to induce transformation of Syrian hamster cells.

Journal: Carcinogenesis 19830101

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