82586-52-5,MFCD00940481
Catalog No.:AA004XKD

82586-52-5 | Moexipril HCl

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
98%(HPLC)
in stock  
$43.00   $30.00
- +
25mg
98%(HPLC)
in stock  
$86.00   $60.00
- +
50mg
98%(HPLC)
in stock  
$142.00   $99.00
- +
100mg
98%(HPLC)
in stock  
$239.00   $167.00
- +
250mg
98%(HPLC)
in stock  
$404.00   $283.00
- +
1g
98%(HPLC)
in stock  
$1,086.00   $760.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA004XKD
Chemical Name:
Moexipril HCl
CAS Number:
82586-52-5
Molecular Formula:
C27H35ClN2O7
Molecular Weight:
535.0290
MDL Number:
MFCD00940481
SMILES:
CCOC(=O)[C@@H](N[C@H](C(=O)N1Cc2cc(OC)c(cc2C[C@H]1C(=O)O)OC)C)CCc1ccccc1.Cl
Properties
Properties
 
BP:
709.3°C at 760 mmHg  
Form:
Solid  
MP:
152-154℃  
Storage:
Inert atmosphere;2-8℃;  

Computed Properties
 
Complexity:
742  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
37  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
12  

Literature

Title: A rapid and sensitive liquid chromatography-tandem mass spectrometric assay for moexipril, an angiotensin-converting enzyme inhibitor in human plasma.

Journal: Biomedical chromatography : BMC 20121201

Title: Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceutical preparations.

Journal: Journal of fluorescence 20120101

Title: First order derivative spectrophotometric and HPLC methods for determination of moexipril hydrochloride in the pure form, pharmeceutical formulations and evaluation of its stability.

Journal: Acta poloniae pharmaceutica 20120101

Title: Determination of antihypertensive drug moexipril hydrochloride based on the enhancement effect of sodium dodecyl sulfate at carbon paste electrode.

Journal: Talanta 20100415

Title: Moexipril for treatment of primary biliary cirrhosis in patients with an incomplete response to ursodeoxycholic acid.

Journal: Digestive diseases and sciences 20100201

Title: [Preventive pharmacotherapy in arterial hypertension: problems of clinical assessment of drugs in women].

Journal: Kardiologiia 20090101

Title: Moexipril and left ventricular hypertrophy.

Journal: Vascular health and risk management 20070201

Title: Metabolism of moexipril to moexiprilat: determination of in vitro metabolism using HPLC-ES-MS.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates)) 20070101

Title: [Assessment of the effect of angiotensin converting enzyme inhibitor moexipril on the functional state of vascular wall in patients with I - III degree arterial hypertension].

Journal: Kardiologiia 20070101

Title: Monitoring the metabolism of moexipril to moexiprilat using high-performance liquid chromatography-electrospray ionization mass spectrometry.

Journal: Journal of chromatographic science 20060401

Title: [Comparative efficacy and safety of contemporary Angiotensin converting enzyme inhibitors moexipril and spirapril in women with postmenopausal metabolic syndrome].

Journal: Kardiologiia 20060101

Title: [Investigation of efficacy of cardiovascular drugs in women].

Journal: Kardiologiia 20060101

Title: [Hypotensive, organoprotective, and metabolic effects of Angiotensin converting enzyme inhibitor moexipril in women with postmenopausal syndrome].

Journal: Kardiologiia 20060101

Title: [Moexipril and cardiovascular diseases in women: is there a reason for optimism?].

Journal: Kardiologiia 20060101

Title: [Dynamics of left ventricular longitudinal function in patients with arterial hypertension during therapy with angiotensin converting enzyme inhibitor moexipril].

Journal: Kardiologiia 20060101

Title: [Angiotensin converting enzyme inhibitor moexipril in the treatment of arterial hypertension. Possibilities of moexipril in the treatment of postmenopausal women].

Journal: Kardiologiia 20060101

Title: Subchronic exposure to high-dose ACE-inhibitor moexipril induces catalase activity in rat liver.

Journal: Molecular and cellular biochemistry 20051201

Title: MORE--MOexipril and REgression of left ventricle hypertrophy in combination therapy A multicentric open label clinical trial.

Journal: International journal of cardiology 20050420

Title: Regression of left ventricular hypertrophy with moexipril, an angiotensin-converting enzyme inhibitor, in hypertensive patients.

Journal: American journal of therapeutics 20050101

Title: [Hemodynamic and anti-ischemic effects of moexipril in patients having postinfarction heart dysfunction and moderate left ventricular heart failure].

Journal: Klinicheskaia meditsina 20050101

Title: [The use of moexipril in postmenopausal women with hypertension and associated changes of bone mineral density].

Journal: Kardiologiia 20050101

Title: [Moexipril influence on quality of life in postmenopausal women with arterial hypertension].

Journal: Terapevticheskii arkhiv 20050101

Title: [Assessment of antihypertensive efficacy of moexipril in metabolic syndrome].

Journal: Kardiologiia 20050101

Title: Pharmacological and clinical profile of moexipril: a concise review.

Journal: Journal of clinical pharmacology 20040801

Title: The influence of relative humidity and temperature on stability of moexipril hydrochloride in solid phase.

Journal: Acta poloniae pharmaceutica 20040101

Title: Simultaneous determination of moexipril hydrochloride and hydrochlorothiazide in tablets by derivative spectrophotometric and high-performance liquid chromatographic methods.

Journal: Journal of pharmaceutical and biomedical analysis 20031015

Title: Pharmacological profile and clinical use of moexipril.

Journal: Expert review of cardiovascular therapy 20030901

Title: Moexipril and quinapril inhibition of tissue angiotensin-converting enzyme activity in the rat: evidence for direct effects in heart, lung and kidney and stimulation of prostacyclin generation.

Journal: Journal of endocrinological investigation 20030101

Title: ACE Inhibition with moexipril: a review of potential effects beyond blood pressure control.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions 20030101

Title: Using ACE inhibitors appropriately.

Journal: American family physician 20020801

Title: Oestrogen action on the myocardium in vivo: specific and permissive for angiotensin-converting enzyme inhibition.

Journal: Journal of hypertension 20020501

Title: Should perindopril be used to treat patients with heart failure?

Journal: American family physician 20020501

Title: Reversal of left ventricular hypertrophy with the ACE inhibitor moexipril in patients with essential hypertension.

Journal: Acta cardiologica 20020201

Title: Moexipril shows a long duration of action related to an extended pharmacokinetic half-life and prolonged ACE inhibition.

Journal: International journal of clinical pharmacology and therapeutics 20020101

Title: Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats.

Journal: European journal of pharmacology 19990528

Title: Increased arterial distensibility in postmenopausal hypertensive women with and without hormone replacement therapy after acute administration of the ACE inhibitor moexipril.

Journal: Cardiovascular drugs and therapy 19980901

Title: Moexipril. A review of its use in the management of essential hypertension.

Journal: Drugs 19980601

Title: Antihypertensive treatment in postmenopausal women: results from a prospective, randomized, double-blind, controlled study comparing an ACE inhibitor (moexipril) with a diuretic (hydrochlorothiazide).

Journal: Cardiology 19980501

Title: Impact of antihypertensive therapy on the skeleton: effects of moexipril and hydrochlorothiazide on osteopenia in spontaneously hypertensive ovariectomized rats.

Journal: The Journal of endocrinology 19970901

Title: Pharmacological and toxicological studies of the new angiotensin converting enzyme inhibitor moexipril hydrochloride.

Journal: Arzneimittel-Forschung 19970201

Title: Evaluation of the antihypertensive efficacy and tolerability of moexipril, a new ACE inhibitor, compared to hydrochlorothiazide in elderly patients.

Journal: European journal of clinical pharmacology 19960101

Title: Tricenter assessment of the efficacy of the ACE inhibitor, moexipril, by ambulatory blood pressure monitoring.

Journal: Journal of clinical pharmacology 19950301

Title: Evidence for site-specific absorption of a novel ACE inhibitor.

Journal: Pharmaceutical research 19890901

Title: Chrysant, S.G. and G.S. Chrysant, Pharmacological and clinical profile of moexipril: a concise review. J Clin Pharmacol, 2004. 44(8): p. 827-36.

Title: Friehe H, et al. Pharmacological and toxicological studies of the new angiotensin converting enzyme inhibitor moexipril hydrochloride. Arzneimittelforschung. 1997 Feb. 47(2):132-44.

Title: Edling, O., et al., Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril. J Pharmacol Exp Ther, 1995. 275(2): p. 854-63.

Title: Ravati A, et al. Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats. Eur J Pharmacol. 1999 May 28;373(1):21-33.

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SDS
Tags:82586-52-5 Molecular Formula|82586-52-5 MDL|82586-52-5 SMILES|82586-52-5 Moexipril HCl
Catalog No.: AA004XKD
82586-52-5,MFCD00940481
82586-52-5 | Moexipril HCl
Pack Size: 10mg
Purity: 98%(HPLC)
in stock
$43.00 $30.00
Pack Size: 25mg
Purity: 98%(HPLC)
in stock
$86.00 $60.00
Pack Size: 50mg
Purity: 98%(HPLC)
in stock
$142.00 $99.00
Pack Size: 100mg
Purity: 98%(HPLC)
in stock
$239.00 $167.00
Pack Size: 250mg
Purity: 98%(HPLC)
in stock
$404.00 $283.00
Pack Size: 1g
Purity: 98%(HPLC)
in stock
$1,086.00 $760.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA004XKD
Chemical Name: Moexipril HCl
CAS Number: 82586-52-5
Molecular Formula: C27H35ClN2O7
Molecular Weight: 535.0290
MDL Number: MFCD00940481
SMILES: CCOC(=O)[C@@H](N[C@H](C(=O)N1Cc2cc(OC)c(cc2C[C@H]1C(=O)O)OC)C)CCc1ccccc1.Cl
Properties
BP: 709.3°C at 760 mmHg  
Form: Solid  
MP: 152-154℃  
Storage: Inert atmosphere;2-8℃;  
Complexity: 742  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 3  
Heavy Atom Count: 37  
Hydrogen Bond Acceptor Count: 8  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 12  
Literature fold

Title: A rapid and sensitive liquid chromatography-tandem mass spectrometric assay for moexipril, an angiotensin-converting enzyme inhibitor in human plasma.

Journal: Biomedical chromatography : BMC20121201

Title: Spectrofluorimetric determination of etodolac, moxepril HCl and fexofenadine HCl using europium sensitized fluorescence in bulk and pharmaceutical preparations.

Journal: Journal of fluorescence20120101

Title: First order derivative spectrophotometric and HPLC methods for determination of moexipril hydrochloride in the pure form, pharmeceutical formulations and evaluation of its stability.

Journal: Acta poloniae pharmaceutica20120101

Title: Determination of antihypertensive drug moexipril hydrochloride based on the enhancement effect of sodium dodecyl sulfate at carbon paste electrode.

Journal: Talanta20100415

Title: Moexipril for treatment of primary biliary cirrhosis in patients with an incomplete response to ursodeoxycholic acid.

Journal: Digestive diseases and sciences20100201

Title: [Preventive pharmacotherapy in arterial hypertension: problems of clinical assessment of drugs in women].

Journal: Kardiologiia20090101

Title: Moexipril and left ventricular hypertrophy.

Journal: Vascular health and risk management20070201

Title: Metabolism of moexipril to moexiprilat: determination of in vitro metabolism using HPLC-ES-MS.

Journal: Medicinal chemistry (Shariqah (United Arab Emirates))20070101

Title: [Assessment of the effect of angiotensin converting enzyme inhibitor moexipril on the functional state of vascular wall in patients with I - III degree arterial hypertension].

Journal: Kardiologiia20070101

Title: Monitoring the metabolism of moexipril to moexiprilat using high-performance liquid chromatography-electrospray ionization mass spectrometry.

Journal: Journal of chromatographic science20060401

Title: [Comparative efficacy and safety of contemporary Angiotensin converting enzyme inhibitors moexipril and spirapril in women with postmenopausal metabolic syndrome].

Journal: Kardiologiia20060101

Title: [Investigation of efficacy of cardiovascular drugs in women].

Journal: Kardiologiia20060101

Title: [Hypotensive, organoprotective, and metabolic effects of Angiotensin converting enzyme inhibitor moexipril in women with postmenopausal syndrome].

Journal: Kardiologiia20060101

Title: [Moexipril and cardiovascular diseases in women: is there a reason for optimism?].

Journal: Kardiologiia20060101

Title: [Dynamics of left ventricular longitudinal function in patients with arterial hypertension during therapy with angiotensin converting enzyme inhibitor moexipril].

Journal: Kardiologiia20060101

Title: [Angiotensin converting enzyme inhibitor moexipril in the treatment of arterial hypertension. Possibilities of moexipril in the treatment of postmenopausal women].

Journal: Kardiologiia20060101

Title: Subchronic exposure to high-dose ACE-inhibitor moexipril induces catalase activity in rat liver.

Journal: Molecular and cellular biochemistry20051201

Title: MORE--MOexipril and REgression of left ventricle hypertrophy in combination therapy A multicentric open label clinical trial.

Journal: International journal of cardiology20050420

Title: Regression of left ventricular hypertrophy with moexipril, an angiotensin-converting enzyme inhibitor, in hypertensive patients.

Journal: American journal of therapeutics20050101

Title: [Hemodynamic and anti-ischemic effects of moexipril in patients having postinfarction heart dysfunction and moderate left ventricular heart failure].

Journal: Klinicheskaia meditsina20050101

Title: [The use of moexipril in postmenopausal women with hypertension and associated changes of bone mineral density].

Journal: Kardiologiia20050101

Title: [Moexipril influence on quality of life in postmenopausal women with arterial hypertension].

Journal: Terapevticheskii arkhiv20050101

Title: [Assessment of antihypertensive efficacy of moexipril in metabolic syndrome].

Journal: Kardiologiia20050101

Title: Pharmacological and clinical profile of moexipril: a concise review.

Journal: Journal of clinical pharmacology20040801

Title: The influence of relative humidity and temperature on stability of moexipril hydrochloride in solid phase.

Journal: Acta poloniae pharmaceutica20040101

Title: Simultaneous determination of moexipril hydrochloride and hydrochlorothiazide in tablets by derivative spectrophotometric and high-performance liquid chromatographic methods.

Journal: Journal of pharmaceutical and biomedical analysis20031015

Title: Pharmacological profile and clinical use of moexipril.

Journal: Expert review of cardiovascular therapy20030901

Title: Moexipril and quinapril inhibition of tissue angiotensin-converting enzyme activity in the rat: evidence for direct effects in heart, lung and kidney and stimulation of prostacyclin generation.

Journal: Journal of endocrinological investigation20030101

Title: ACE Inhibition with moexipril: a review of potential effects beyond blood pressure control.

Journal: American journal of cardiovascular drugs : drugs, devices, and other interventions20030101

Title: Using ACE inhibitors appropriately.

Journal: American family physician20020801

Title: Oestrogen action on the myocardium in vivo: specific and permissive for angiotensin-converting enzyme inhibition.

Journal: Journal of hypertension20020501

Title: Should perindopril be used to treat patients with heart failure?

Journal: American family physician20020501

Title: Reversal of left ventricular hypertrophy with the ACE inhibitor moexipril in patients with essential hypertension.

Journal: Acta cardiologica20020201

Title: Moexipril shows a long duration of action related to an extended pharmacokinetic half-life and prolonged ACE inhibition.

Journal: International journal of clinical pharmacology and therapeutics20020101

Title: Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats.

Journal: European journal of pharmacology19990528

Title: Increased arterial distensibility in postmenopausal hypertensive women with and without hormone replacement therapy after acute administration of the ACE inhibitor moexipril.

Journal: Cardiovascular drugs and therapy19980901

Title: Moexipril. A review of its use in the management of essential hypertension.

Journal: Drugs19980601

Title: Antihypertensive treatment in postmenopausal women: results from a prospective, randomized, double-blind, controlled study comparing an ACE inhibitor (moexipril) with a diuretic (hydrochlorothiazide).

Journal: Cardiology19980501

Title: Impact of antihypertensive therapy on the skeleton: effects of moexipril and hydrochlorothiazide on osteopenia in spontaneously hypertensive ovariectomized rats.

Journal: The Journal of endocrinology19970901

Title: Pharmacological and toxicological studies of the new angiotensin converting enzyme inhibitor moexipril hydrochloride.

Journal: Arzneimittel-Forschung19970201

Title: Evaluation of the antihypertensive efficacy and tolerability of moexipril, a new ACE inhibitor, compared to hydrochlorothiazide in elderly patients.

Journal: European journal of clinical pharmacology19960101

Title: Tricenter assessment of the efficacy of the ACE inhibitor, moexipril, by ambulatory blood pressure monitoring.

Journal: Journal of clinical pharmacology19950301

Title: Evidence for site-specific absorption of a novel ACE inhibitor.

Journal: Pharmaceutical research19890901

Title: Chrysant, S.G. and G.S. Chrysant, Pharmacological and clinical profile of moexipril: a concise review. J Clin Pharmacol, 2004. 44(8): p. 827-36.

Title: Friehe H, et al. Pharmacological and toxicological studies of the new angiotensin converting enzyme inhibitor moexipril hydrochloride. Arzneimittelforschung. 1997 Feb. 47(2):132-44.

Title: Edling, O., et al., Moexipril, a new angiotensin-converting enzyme (ACE) inhibitor: pharmacological characterization and comparison with enalapril. J Pharmacol Exp Ther, 1995. 275(2): p. 854-63.

Title: Ravati A, et al. Enalapril and moexipril protect from free radical-induced neuronal damage in vitro and reduce ischemic brain injury in mice and rats. Eur J Pharmacol. 1999 May 28;373(1):21-33.

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