Title: Stereospecific Metabolism of the Tobacco-Specific Nitrosamine, NNAL.
Journal: Chemical research in toxicology 20151116
Title: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism-related enzymes gene polymorphisms, NNK metabolites levels and urothelial carcinoma.
Journal: Toxicology letters 20130110
Title: The impact of Michigan's Dr Ron Davis smoke-free air law on levels of cotinine, tobacco-specific lung carcinogen and severity of self-reported respiratory symptoms among non-smoking bar employees.
Journal: Tobacco control 20121101
Title: Development, validation, and application of a liquid chromatography-tandem mass spectrometry method for the determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human hair.
Journal: Analytical and bioanalytical chemistry 20121101
Title: Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin.
Journal: International journal of cancer 20120915
Title: Interplay between smoking-induced genotoxicity and altered signaling in pancreatic carcinogenesis.
Journal: Carcinogenesis 20120901
Title: Exposure to secondhand smoke outside of a bar and a restaurant and tobacco exposure biomarkers in nonsmokers.
Journal: Environmental health perspectives 20120701
Title: In vivo and in vitro metabolism of tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), by the freshwater planarian, Dugesia japonica.
Journal: Chemosphere 20120601
Title: Smoking behavior and exposure to tobacco toxicants during 6 months of smoking progressively reduced nicotine content cigarettes.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20120501
Title: Exposure and kinetics of polycyclic aromatic hydrocarbons (PAHs) in cigarette smokers.
Journal: Chemical research in toxicology 20120416
Title: Development of a method for the determination of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine of nonsmokers and smokers using liquid chromatography/tandem mass spectrometry.
Journal: Journal of pharmaceutical and biomedical analysis 20120407
Title: Role of CYP2A5 in the bioactivation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mice.
Journal: The Journal of pharmacology and experimental therapeutics 20120401
Title: Genetic variability in the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) to 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).
Journal: International journal of cancer 20120315
Title: Environmental tobacco smoke and children's health.
Journal: Korean journal of pediatrics 20120201
Title: European birth cohorts for environmental health research.
Journal: Environmental health perspectives 20120101
Title: 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanone is correlated with 8-hydroxy-2'-deoxyguanosine in humans after exposure to environmental tobacco smoke.
Journal: The Science of the total environment 20120101
Title: Cancer chemoprevention by citrus pulp and juices containing high amounts of β-cryptoxanthin and hesperidin.
Journal: Journal of biomedicine & biotechnology 20120101
Title: Reduced exercise tolerance and pulmonary capillary recruitment with remote secondhand smoke exposure.
Journal: PloS one 20120101
Title: Estimation and correlation of cigarette smoke exposure in Canadian smokers as determined by filter analysis and biomarkers of exposure.
Journal: Regulatory toxicology and pharmacology : RTP 20111201
Title: A study to evaluate the effect on Mouth Level Exposure and biomarkers of exposure estimates of cigarette smoke exposure following a forced switch to a lower ISO tar yield cigarette.
Journal: Regulatory toxicology and pharmacology : RTP 20111201
Title: Nicotine, carbon monoxide, and carcinogen exposure after a single use of a water pipe.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20111101
Title: Urinary levels of cigarette smoke constituent metabolites are prospectively associated with lung cancer development in smokers.
Journal: Cancer research 20111101
Title: Prevention of mouse lung tumors by combinations of chemopreventive agents using concurrent and sequential administration.
Journal: Anticancer research 20111001
Title: STrengthening the Reporting of OBservational studies in Epidemiology--Molecular Epidemiology (STROBE-ME): an extension of the STROBE Statement.
Journal: PLoS medicine 20111001
Title: Metabolic study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to the enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in vitro in human bronchial epithelial cells using chiral capillary electrophoresis.
Journal: Journal of chromatography. A 20110916
Title: Mainstream smoke of the waterpipe: does this environmental matrix reveal as significant source of toxic compounds?
Journal: Toxicology letters 20110910
Title: Racial differences in the relationship between number of cigarettes smoked and nicotine and carcinogen exposure.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110901
Title: Urinary levels of the tobacco-specific carcinogen N'-nitrosonornicotine and its glucuronide are strongly associated with esophageal cancer risk in smokers.
Journal: Carcinogenesis 20110901
Title: The ratio of a urinary tobacco-specific lung carcinogen metabolite to cotinine is significantly higher in passive than in active smokers.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20110901
Title: The use of a novel tobacco-substitute sheet and smoke dilution to reduce toxicant yields in cigarette smoke.
Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20110801
Title: Relationship between biomarkers of cigarette smoke exposure and biomarkers of inflammation, oxidative stress, and platelet activation in adult cigarette smokers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110801
Title: Facile syntheses of O(2)-[4-(3-pyridyl-4-oxobut-1-yl]thymidine, the major adduct formed by tobacco specific nitrosamine 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in vivo, and its site-specifically adducted oligodeoxynucleotides.
Journal: Chemical research in toxicology 20110620
Title: Metabolites of a tobacco-specific lung carcinogen in children exposed to secondhand or thirdhand tobacco smoke in their homes.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110601
Title: Metabolic effects of CYP2A6 and CYP2A13 on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-induced gene mutation--a mammalian cell-based mutagenesis approach.
Journal: Toxicology and applied pharmacology 20110601
Title: Effect of maternal tobacco smoking or exposure to second-hand smoke on the levels of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine of mother and the first urine of newborn.
Journal: Journal of physiology and pharmacology : an official journal of the Polish Physiological Society 20110601
Title: Global surveillance of oral tobacco products: total nicotine, unionised nicotine and tobacco-specific N-nitrosamines.
Journal: Tobacco control 20110501
Title: Low ratio of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol-glucuronides (NNAL-Gluc)/free NNAL increases urothelial carcinoma risk.
Journal: The Science of the total environment 20110401
Title: Environmental tobacco smoke exposure among casino dealers.
Journal: Journal of occupational and environmental medicine 20110401
Title: Tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in smokers in the United States: NHANES 2007-2008.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20110301
Title: Is 24h nicotine equivalents a surrogate for smoke exposure based on its relationship with other biomarkers of exposure?
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20110301
Title: Comparison of urine cotinine and the tobacco-specific nitrosamine metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and their ratio to discriminate active from passive smoking.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20110301
Title: Urinary excretion of the acrylonitrile metabolite 2-cyanoethylmercapturic acid is correlated with a variety of biomarkers of tobacco smoke exposure and consumption.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20110201
Title: Characterization of UDP-glucuronosyltransferase 2A1 (UGT2A1) variants and their potential role in tobacco carcinogenesis.
Journal: Pharmacogenetics and genomics 20110201
Title: Nicotine metabolite ratio predicts smoking topography and carcinogen biomarker level.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110201
Title: Microfluidic direct injection method for analysis of urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) using molecularly imprinted polymers coupled on-line with LC-MS/MS.
Journal: Journal of pharmaceutical and biomedical analysis 20110125
Title: A new liquid chromatography/mass spectrometry method for 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in urine.
Journal: Rapid communications in mass spectrometry : RCM 20110115
Title: Biomarkers increase detection of active smoking and secondhand smoke exposure in critically ill patients.
Journal: Critical care medicine 20110101
Title: Effect of oral snus and medicinal nicotine in smokers on toxicant exposure and withdrawal symptoms: a feasibility study.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20110101
Title: Lysyl oxidase, a critical intra- and extra-cellular target in the lung for cigarette smoke pathogenesis.
Journal: International journal of environmental research and public health 20110101
Title: Paternal smoking and risk of childhood acute lymphoblastic leukemia: systematic review and meta-analysis.
Journal: Journal of oncology 20110101
Title: The scientific foundation for tobacco harm reduction, 2006-2011.
Journal: Harm reduction journal 20110101
Title: Urinary biomarkers for secondhand smoke.
Journal: Journal of clinical laboratory analysis 20110101
Title: Disturbances in the glutathione/ophthalmate redox buffer system in the woodchuck model of hepatitis virus-induced hepatocellular carcinoma.
Journal: HPB surgery : a world journal of hepatic, pancreatic and biliary surgery 20110101
Title: Design and study protocol of the maternal smoking cessation during pregnancy study, (M-SCOPE).
Journal: BMC public health 20110101
Title: Urine menthol as a biomarker of mentholated cigarette smoking.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20101201
Title: Urine cotinine underestimates exposure to the tobacco-derived lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in passive compared with active smokers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20101101
Title: Urine concentrations of a tobacco-specific nitrosamine carcinogen in the U.S. population from secondhand smoke exposure.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20101101
Title: On-line concentration and determination of tobacco-specific N-nitrosamines by cation-selective exhaustive injection-sweeping-micellar electrokinetic chromatography.
Journal: Talanta 20101015
Title: Chinese 'low-tar' cigarettes do not deliver lower levels of nicotine and carcinogens.
Journal: Tobacco control 20101001
Title: Stability of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine samples stored at various temperatures.
Journal: Journal of analytical toxicology 20100901
Title: Temporal stability of urinary and plasma biomarkers of tobacco smoke exposure among cigarette smokers.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20100601
Title: Effect of differing levels of tobacco-specific nitrosamines in cigarette smoke on the levels of biomarkers in smokers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100601
Title: Formation and distribution of NNK metabolites in an isolated perfused rat lung.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100501
Title: Tobacco smoke exposure in nonsmoking hospitality workers before and after a state smoking ban.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20100401
Title: UDP-glucuronosyltransferase 1A10: activity against the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and a potential role for a novel UGT1A10 promoter deletion polymorphism in cancer susceptibility.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20100301
Title: Adaptive regression modeling of biomarkers of potential harm in a population of U.S. adult cigarette smokers and nonsmokers.
Journal: BMC medical research methodology 20100101
Title: Associations of variants in CHRNA5/A3/B4 gene cluster with smoking behaviors in a Korean population.
Journal: PloS one 20100101
Title: Role of glutathione in the regulation of Cisplatin resistance in cancer chemotherapy.
Journal: Metal-based drugs 20100101
Title: Determination of tobacco-specific N-nitrosamines in urine of smokers and non-smokers.
Journal: Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 20091201
Title: Elimination kinetics of the tobacco-specific biomarker and lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20091201
Title: Chinese 'herbal' cigarettes are as carcinogenic and addictive as regular cigarettes.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20091201
Title: Exposure to the carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in smokers from 3 populations with different risks of lung cancer.
Journal: International journal of cancer 20091115
Title: Population estimates for biomarkers of exposure to cigarette smoke in adult U.S. cigarette smokers.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20091001
Title: Longer term exposure to secondhand smoke and health outcomes in COPD: impact of urine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20090801
Title: A comparison of exposure to carcinogens among roll-your-own and factory-made cigarette smokers.
Journal: Addiction biology 20090701
Title: Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung tissue from mouse, rat, hamster, and man.
Journal: Chemical research in toxicology 20090601
Title: A modified method for the determination of tobacco specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine by solid phase extraction using a molecularly imprinted polymer and liquid chromatography tandem mass spectrometry.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090515
Title: Analysis of pyridyloxobutyl and pyridylhydroxybutyl DNA adducts in extrahepatic tissues of F344 rats treated chronically with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Journal: Chemical research in toxicology 20090501
Title: Effects of smoking cessation on eight urinary tobacco carcinogen and toxicant biomarkers.
Journal: Chemical research in toxicology 20090401
Title: Urinary levels of tobacco-specific nitrosamine metabolites in relation to lung cancer development in two prospective cohorts of cigarette smokers.
Journal: Cancer research 20090401
Title: Mitochondrial DNA adducts in the lung and liver of F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and (S)-4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Journal: Chemical research in toxicology 20090201
Title: A prospectively measured serum biomarker for a tobacco-specific carcinogen and lung cancer in smokers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20090101
Title: Evidence for endogenous formation of N'-nitrosonornicotine in some long-term nicotine patch users.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20090101
Title: Evaluation of biomarkers of exposure and potential harm in smokers, former smokers and never-smokers.
Journal: Clinical chemistry and laboratory medicine 20090101
Title: Nicotine metabolism in three ethnic/racial groups with different risks of lung cancer.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081201
Title: Correlation between the urine profile of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolites and N7-methylguanine in urothelial carcinoma patients.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20081201
Title: Smokers with the CHRNA lung cancer-associated variants are exposed to higher levels of nicotine equivalents and a carcinogenic tobacco-specific nitrosamine.
Journal: Cancer research 20081115
Title: Subpicogram per milliliter determination of the tobacco-specific carcinogen metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human urine using liquid chromatography-tandem mass spectrometry.
Journal: Analytical chemistry 20081101
Title: Surveillance of moist snuff: total nicotine, moisture, pH, un-ionized nicotine, and tobacco-specific nitrosamines.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20081101
Title: [Study advances on carcinogens and their metabolites in urine of smokers].
Journal: Wei sheng yan jiu = Journal of hygiene research 20081101
Title: Effect of COPD treatments on MRP1-mediated transport in bronchial epithelial cells.
Journal: International journal of chronic obstructive pulmonary disease 20080901
Title: Quantitation of pyridylhydroxybutyl-DNA adducts in liver and lung of F-344 rats treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Journal: Chemical research in toxicology 20080701
Title: Extensive metabolic activation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in smokers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080701
Title: A 12-month, randomized, controlled study to evaluate exposure and cardiovascular risk factors in adult smokers switching from conventional cigarettes to a second-generation electrically heated cigarette smoking system.
Journal: Journal of clinical pharmacology 20080501
Title: Exposure to nicotine and a tobacco-specific carcinogen increase with duration of use of smokeless tobacco.
Journal: Tobacco control 20080401
Title: Detection and quantitation of N'-nitrosonornicotine in human toenails by liquid chromatography-electrospray ionization-tandem mass spectrometry.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080401
Title: Formation of formaldehyde adducts in the reactions of DNA and deoxyribonucleosides with alpha-acetates of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), and N-nitrosodimethylamine (NDMA).
Journal: Chemical research in toxicology 20080301
Title: Smoking reduction fails to improve clinical and biological markers of cardiac disease: a randomized controlled trial.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20080301
Title: Metabolism of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone to its biomarker total NNAL in smokeless tobacco users.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20080301
Title: Biotransformation and transport of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in bile duct-cannulated wild-type and Mrp2/Abcc2-deficient (TR ) Wistar rats.
Journal: Carcinogenesis 20071201
Title: Analysis of CYP2A contributions to metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in human peripheral lung microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20071101
Title: Nicotine and carcinogen exposure with smoking of progressively reduced nicotine content cigarette.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20071101
Title: The association of a tobacco-specific biomarker and cigarette consumption and its dependence on host characteristics.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070901
Title: Determination of the role of target tissue metabolism in lung carcinogenesis using conditional cytochrome P450 reductase-null mice.
Journal: Cancer research 20070815
Title: Similar exposure to a tobacco-specific carcinogen in smokeless tobacco users and cigarette smokers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070801
Title: Relationship of human toenail nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol to levels of these biomarkers in plasma and urine.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070701
Title: Urinary biomarkers to assess exposure of cats to environmental tobacco smoke.
Journal: American journal of veterinary research 20070401
Title: The UDP-glucuronosyltransferase 2B17 gene deletion polymorphism: sex-specific association with urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol glucuronidation phenotype and risk for lung cancer.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20070401
Title: An association of CYP2A6 genotype and smoking topography.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20070401
Title: Smokeless tobacco brand switching: a means to reduce toxicant exposure?
Journal: Drug and alcohol dependence 20070316
Title: Relationship between machine-derived smoke yields and biomarkers in cigarette smokers in Germany.
Journal: Regulatory toxicology and pharmacology : RTP 20070301
Title: Formation and accumulation of pyridyloxobutyl DNA adducts in F344 rats chronically treated with 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and enantiomers of its metabolite, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.
Journal: Chemical research in toxicology 20070201
Title: Effects of high dose transdermal nicotine replacement in cigarette smokers.
Journal: Pharmacology, biochemistry, and behavior 20070101
Title: Reduced inflammatory response in cigarette smoke exposed Mrp1/Mdr1a/1b deficient mice.
Journal: Respiratory research 20070101
Title: Meat, vegetables and genetic polymorphisms and the risk of colorectal carcinomas and adenomas.
Journal: BMC cancer 20070101
Title: Determination of tobacco specific hemoglobin adducts in smoking mothers and new born babies by mass spectrometry.
Journal: Biomarker insights 20070101
Title: A comparison of nicotine dose estimates in smokers between filter analysis, salivary cotinine, and urinary excretion of nicotine metabolites.
Journal: Psychopharmacology 20061201
Title: Study of the metabolism on tobacco-specific N-nitrosamines in the rabbit by solid-phase extraction and liquid chromatography-tandem mass spectrometry.
Journal: Analytical and bioanalytical chemistry 20061201
Title: Toxicant exposure in cigarette reducers versus light smokers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20061201
Title: Mass spectrometric quantitation of nicotine, cotinine, and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in human toenails.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20061201
Title: A biomarker of exposure to environmental tobacco smoke (ETS) and Ernst Wynder's opinion about ETS and lung cancer.
Journal: Preventive medicine 20061001
Title: Combined analysis of r-1,t-2,3,c-4-tetrahydroxy-1,2,3,4-tetrahydrophenanthrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in smokers' plasma.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060801
Title: [Detection of metabolites of tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in lung cancer smokers' urine].
Journal: Zhongguo fei ai za zhi = Chinese journal of lung cancer 20060620
Title: Determination of tobacco-specific N-nitrosamines in rabbit serum by capillary zone electrophoresis and capillary electrophoresis-electrospray ionization-mass spectrometry with solid-phase extraction.
Journal: Electrophoresis 20060601
Title: Prevention of mouse lung tumors by targretin.
Journal: International journal of cancer 20060501
Title: 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol and its glucuronides in the urine of infants exposed to environmental tobacco smoke.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060501
Title: Uptake of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by Moldovan children.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20060101
Title: Characterization of tamoxifen and 4-hydroxytamoxifen glucuronidation by human UGT1A4 variants.
Journal: Breast cancer research : BCR 20060101
Title: Analysis of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in urine by extraction on a molecularly imprinted polymer column and liquid chromatography/atmospheric pressure ionization tandem mass spectrometry.
Journal: Analytical chemistry 20051201
Title: Relationships between cigarette consumption and biomarkers of tobacco toxin exposure.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20051201
Title: Genotype-phenotype correlation between the polymorphic UGT2B17 gene deletion and NNAL glucuronidation activities in human liver microsomes.
Journal: Pharmacogenetics and genomics 20051101
Title: Analysis of total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol in smokers' blood.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20051101
Title: Urinary tobacco-specific nitrosamines and 4-aminobiphenyl hemoglobin adducts measured in smokers of either regular or light cigarettes.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20051001
Title: Carcinogen exposure during short-term switching from regular to 'light' cigarettes.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050601
Title: Smokeless tobacco topography and toxin exposure.
Journal: Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco 20050601
Title: Urinary metabolites of a tobacco-specific lung carcinogen in nonsmoking hospitality workers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050501
Title: Racial differences in exposure and glucuronidation of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
Journal: Cancer 20050401
Title: Similar uptake of lung carcinogens by smokers of regular, light, and ultralight cigarettes.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20050301
Title: Cytochrome P450 enzymes as catalysts of metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, a tobacco specific carcinogen.
Journal: Chemical research in toxicology 20050201
Title: ATP-binding cassette (ABC) transporters in normal and pathological lung.
Journal: Respiratory research 20050101
Title: A comparison of urinary biomarkers of tobacco and carcinogen exposure in smokers.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20041001
Title: Enantioselectivity of carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone by tissue fractions from human and rat and by enzymes isolated from human liver.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040901
Title: Stereoselective metabolism and tissue retention in rats of the individual enantiomers of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL), metabolites of the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK).
Journal: Carcinogenesis 20040701
Title: Effects of cruciferous vegetable consumption on urinary metabolites of the tobacco-specific lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in singapore chinese.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20040601
Title: Identification of O2-substituted pyrimidine adducts formed in reactions of 4-(acetoxymethylnitrosamino)- 1-(3-pyridyl)-1-butanone and 4-(acetoxymethylnitros- amino)-1-(3-pyridyl)-1-butanol with DNA.
Journal: Chemical research in toxicology 20040501
Title: Carcinogen derived biomarkers: applications in studies of human exposure to secondhand tobacco smoke.
Journal: Tobacco control 20040301
Title: Children's exposure to environmental tobacco smoke: using diverse exposure metrics to document ethnic/racial differences.
Journal: Environmental health perspectives 20040301
Title: Correlation between UDP-glucuronosyltransferase genotypes and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone glucuronidation phenotype in human liver microsomes.
Journal: Cancer research 20040201
Title: Effects of reduced cigarette smoking on the uptake of a tobacco-specific lung carcinogen.
Journal: Journal of the National Cancer Institute 20040121
Title: Characterization of N-glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human liver: importance of UDP-glucuronosyltransferase 1A4.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20040101
Title: Development, validation and transfer of a hydrophilic interaction liquid chromatography/tandem mass spectrometric method for the analysis of the tobacco-specific nitrosamine metabolite NNAL in human plasma at low picogram per milliliter concentrations.
Journal: Rapid communications in mass spectrometry : RCM 20040101
Title: Analysis of total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human urine.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20031101
Title: Comparative metabolism of the tobacco-specific nitrosamines 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol by rat cytochrome P450 2A3 and human cytochrome P450 2A13.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20031001
Title: Biotransformation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in peripheral human lung microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20030901
Title: Synthesis of stereospecifically deuterated 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) iastereomers and metabolism by A/J mouse lung microsomes and cytochrome p450 2A5.
Journal: Chemical research in toxicology 20030601
Title: Immunomodulatory effects of the tobacco-specific carcinogen, NNK, on alveolar macrophages.
Journal: Clinical and experimental immunology 20030501
Title: Effects of benzyl isothiocyanate and 2-phenethyl isothiocyanate on benzo[a]pyrene and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolism in F-344 rats.
Journal: Carcinogenesis 20030301
Title: The pyridyloxobutyl DNA adduct, O6-[4-oxo-4-(3-pyridyl)butyl]guanine, is detected in tissues from 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-treated A/J mice.
Journal: Chemical research in toxicology 20030101
Title: Effect of nicotine, cotinine and phenethyl isothiocyanate on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) metabolism in the Syrian golden hamster.
Journal: Toxicology 20020930
Title: Identification of tobacco-derived compounds in human pancreatic juice.
Journal: Chemical research in toxicology 20020501
Title: Analysis of N- and O-glucuronides of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in human urine.
Journal: Chemical research in toxicology 20020401
Title: Disposition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) in bile duct-cannulated rats: stereoselective metabolism and tissue distribution.
Journal: Carcinogenesis 20020101
Title: Quantitation of metabolites of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone after cessation of smokeless tobacco use.
Journal: Cancer research 20020101
Title: The effect of a 2-h exposure to cigarette smoke on the metabolic activation of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mice.
Journal: Chemico-biological interactions 20011128
Title: Metabolites of a tobacco-specific lung carcinogen in the urine of elementary school-aged children.
Journal: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 20011101
Title: Transport of the beta -O-glucuronide conjugate of the tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the multidrug resistance protein 1 (MRP1). Requirement for glutathione or a non-sulfur-containing analog.
Journal: The Journal of biological chemistry 20010727
Title: The effect of tobacco smoke, nicotine, and cotinine on the mutagenicity of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL).
Journal: Mutation research 20010725
Title: Preparation of pyridine-N-glucuronides of tobacco-specific nitrosamines.
Journal: Chemical research in toxicology 20010501
Title: Effects of vitamins and common drugs on reduction of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rat microsomes.
Journal: Archives of physiology and biochemistry 20010401
Title: Metabolites of a tobacco-specific lung carcinogen in nonsmoking women exposed to environmental tobacco smoke.
Journal: Journal of the National Cancer Institute 20010307
Title: Characterization of enzymes participating in carbonyl reduction of 4-methylnitrosamino-1-(3-pyridyl)-1-butanone (NNK) in human placenta.
Journal: Chemico-biological interactions 20010130
Title: Expression and NNK reducing activities of carbonyl reductase and 11beta-hydroxysteroid dehydrogenase type 1 in human lung.
Journal: Chemico-biological interactions 20010130
Title: Human cervical tissue metabolizes the tobacco-specific nitrosamine, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, via alpha-hydroxylation and carbonyl reduction pathways.
Journal: Carcinogenesis 20010101
Title: Carcinogen biomarkers for lung or oral cancer chemoprevention trials.
Journal: IARC scientific publications 20010101
Title: O-Glucuronidation of the lung carcinogen 4-(methylnitrosamino)-1- (3-pyridyl)-1-butanol (NNAL) by human UDP-glucuronosyltransferases 2B7 and 1A9.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20001101
Title: Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol, and N'- nitrosonornicotine in human hepatic microsomes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 19970201
