73218-79-8,MFCD00135922
Catalog No.:AA005FMP

73218-79-8 | 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$8.00   $6.00
- +
25mg
97%
in stock  
$61.00   $43.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA005FMP
Chemical Name:
2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride
CAS Number:
73218-79-8
Molecular Formula:
C9H11Cl3N4
Molecular Weight:
281.5694
MDL Number:
MFCD00135922
SMILES:
Nc1cc(Cl)c(c(c1)Cl)NC1=NCCN1.Cl
Properties
Properties
 
Form:
Solid  
MP:
>2300C  
Solubility:
45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.4 mg/mL Solutions may be stored for several days at 4?#x00b0;C  
Storage:
Inert atmosphere;Room Temperature;  

Computed Properties
 
Complexity:
247  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
2  

Literature

Title: [Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].

Journal: Journal francais d'ophtalmologie 20121001

Title: Hemifacial flushing after bathing and crying.

Journal: The Journal of pediatrics 20120601

Title: Impact of T3 thoracoscopic sympathectomy on pupillary function: a cause of partial Horner's syndrome?

Journal: Surgical endoscopy 20120401

Title: Pupillometry study of brimonidine tartrate 0.2% and apraclonidine 0.5%.

Journal: Journal of clinical pharmacology 20111201

Title: [α-agonists in ophthalmology].

Journal: Pharmazie in unserer Zeit 20111101

Title: Apraclonidine and my pupil.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society 20111001

Title: Early diagnosis of Horner syndrome using topical apraclonidine.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20110901

Title: Pharmacological diagnosis of Horner's syndrome in the emergency department.

Journal: Emergency medicine journal : EMJ 20110801

Title: Confirmation of Horner's syndrome using apraclonidine eye drops.

Journal: Postgraduate medical journal 20110601

Title: [Acquired Horner's syndrome].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20110520

Title: Teaching NeuroImages: Positive apraclonidine test in Horner syndrome.

Journal: Neurology 20110517

Title: Teaching NeuroImages: honeycomb appearance of the brain in a patient with Canavan disease.

Journal: Neurology 20110329

Title: Horner's syndrome as a complication of percutaneous ethanol treatment of thyroid nodule.

Journal: Thyroid : official journal of the American Thyroid Association 20110301

Title: [Prevention of intraocular pressure elevation after argon laser trabeculoplasty in primary open angle glaucoma].

Journal: Srpski arhiv za celokupno lekarstvo 20110101

Title: Systemic effects of topical ophthalmic agents.

Journal: British journal of anaesthesia 20100801

Title: Using apraclonidine in diagnosing Horner syndrome in children.

Journal: American journal of ophthalmology 20100501

Title: Positive apraclonidine test 36 hours after acute onset of horner syndrome in dorsolateral pontomedullary stroke.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20100301

Title: [Unilateral allergic contact dermatitis of the eyelid caused by Iopimax].

Journal: Actas dermo-sifiliograficas 20091201

Title: A pharmacologic pupillary test in the diagnosis of diabetic autonomic neuropathy.

Journal: Korean journal of ophthalmology : KJO 20091201

Title: Current pharmacologic testing for Horner syndrome.

Journal: Current neurology and neuroscience reports 20090901

Title: Possible effect of systemic sympathicolytic drugs on apraclonidine test.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20090801

Title: Brimonidine and apraclonidine as vasoconstrictors in adjustable strabismus surgery.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20090401

Title: False-negative apraclonidine testing in acute Horner syndrome.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie 20090201

Title: [Usefulness of apraclonidine in the diagnosis of Horner syndrome].

Journal: Archivos de la Sociedad Espanola de Oftalmologia 20090201

Title: Exposure to topical apraclonidine in children with glaucoma.

Journal: Journal of glaucoma 20090101

Title: Topical apraclonidine to diagnose Bernard-Horner syndrome.

Journal: Bulletin de la Societe belge d'ophtalmologie 20090101

Title: Recurrent serous macular detachment after topical ocular hypotensive medication.

Journal: Clinical & experimental optometry 20081101

Title: Positive apraclonidine test within two weeks of onset of Horner syndrome caused by carotid artery dissection.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20080901

Title: Pupillary autonomic neuropathy simulating partial Horner syndrome in diabetes mellitus and its reversal with control of blood glucose.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20080901

Title: False negative apraclonidine test in two patients with Horner syndrome.

Journal: Klinische Monatsblatter fur Augenheilkunde 20080501

Title: Central alpha-2 adrenergic eye drops: case series of 3 pediatric systemic poisonings.

Journal: Pediatric emergency care 20080301

Title: The pupil.

Journal: Current opinion in neurology 20080201

Title: Use of 0.5% apraclonidine solution in evaluation of blepharoptosis.

Journal: Ophthalmic plastic and reconstructive surgery 20080101

Title: The acute morphologic changes that occur at the optic nerve head induced by medical reduction of intraocular pressure.

Journal: Journal of glaucoma 20070901

Title: Apraclonidine in the diagnosis of Horner's syndrome.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 20070701

Title: Adverse effects of apraclonidine used in the diagnosis of Horner syndrome in infants.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus 20070601

Title: Pharmacologic reversal of Horner's syndrome-related ptosis with apraclonidine.

Journal: Ear, nose, & throat journal 20070501

Title: Corneal thickness- and age-related biomechanical properties of the cornea measured with the ocular response analyzer.

Journal: Investigative ophthalmology & visual science 20061201

Title: Topical apraclonidine testing of pupillary sympathetic denervation in diabetic patients.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20061201

Title: Congenital Horner's syndrome and the usefulness of the apraclonidine test in its diagnosis.

Journal: Indian journal of ophthalmology 20060901

Title: Brinzolamide 1% versus apraclonidine 0.5% to prevent intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.

Journal: Journal of cataract and refractive surgery 20060901

Title: Efficacy of apraclonidine 0.5% in the diagnosis of Horner syndrome in pediatric patients under low or high illumination.

Journal: American journal of ophthalmology 20060901

Title: The effect of topical apraclonidine on subconjunctival hemorrhage and flap adherence in LASIK patients.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995) 20060601

Title: Comparing efficacies of 0.5% apraclonidine with 4% cocaine in the diagnosis of horner syndrome in pediatric patients.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20060601

Title: Reduction of anterior-segment vascularity with preoperative topical apraclonidine 1%.

Journal: Journal of cataract and refractive surgery 20060401

Title: Topical apraclonidine testing discloses pupillary sympathetic denervation in diabetic patients.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20060301

Title: Effect of 0.5% apraclonidine on ptosis in Horner syndrome.

Journal: Ophthalmic plastic and reconstructive surgery 20060101

Title: Comparative efficacy of acetazolamide and apraclonidine in the control of intraocular pressure following phacoemulsification.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20060101

Title: Apraclonidine and LASIK.

Journal: Ophthalmology 20051201

Title: The sensitivity and specificity of 0.5% apraclonidine in the diagnosis of oculosympathetic paresis.

Journal: The British journal of ophthalmology 20051101

Title: More than just an ocular solution.

Journal: Emergency medicine journal : EMJ 20051001

Title: Brimonidine 0.15% versus apraclonidine 0.5% for prevention of intraocular pressure elevation after anterior segment laser surgery.

Journal: Journal of cataract and refractive surgery 20050901

Title: Are we ready to replace cocaine with apraclonidine in the pharmacologic diagnosis of Horner syndrome?

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20050601

Title: Topical apraclonidine in the diagnosis of suspected Horner syndrome.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society 20050601

Title: The utility of 0.5% apraclonidine in the diagnosis of horner syndrome.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20050401

Title: The use of apraclonidine eyedrops to treat ptosis after the administration of botulinum toxin to the upper face.

Journal: Dermatology online journal 20050301

Title: Treatment of ptosis as a complication of botulinum toxin injection.

Journal: Pain medicine (Malden, Mass.) 20050101

Title: Comparing brimonidine 0.2% to apraclonidine 1.0% in the prevention of intraocular pressure elevation and their pupillary effects following laser peripheral iridotomy.

Journal: Japanese journal of ophthalmology 20050101

Title: Effect of apraclonidine versus dorzolamide on intraocular pressure after phacoemulsification.

Journal: Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye 20050101

Title: Neodymium:yttrium-aluminum-garnet capsulotomy and intraocular pressure in pseudophakic patients with glaucoma.

Journal: Ophthalmology 20040701

Title: The effect of alpha2-agonist on IOP rise following Nd-YAG laser iridotomy.

Journal: The Tokai journal of experimental and clinical medicine 20040401

Title: The use of apraclonidine in the diagnosis of horner syndrome in pediatric patients.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20040201

Title: Double-blind parallel comparison of multiple doses of apraclonidine, clonidine, and placebo administered intra-articularly to patients undergoing arthroscopic knee surgery.

Journal: The Clinical journal of pain 20040101

Title: The utility of 0.5% apraclonidine in the diagnosis of horner syndrome.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20030801

Title: The effect of topical glaucoma medications evaluated by perimetry.

Journal: The British journal of ophthalmology 20030601

Title: Ocular perfusion pressure and visual field indice modifications induced by alpha-agonist compound (clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2%) topical administration. An acute study on primary open-angle glaucoma patients.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20030101

Title: Preventing intraocular pressure increase after phacoemulsification and the role of perioperative apraclonidine.

Journal: Journal of cataract and refractive surgery 20021201

Title: Dorzolamide X apraclonidine in the prevention of the intraocular pressure spike after Nd : YAG laser posterior capsulotomy.

Journal: Current eye research 20021001

Title: Effects of topical antiglaucoma eye drops on prostaglandin E(2)-induced aqueous flare elevation in pigmented rabbits.

Journal: Investigative ophthalmology & visual science 20020401

Title: Apraclonidine attenuates the increases in spinal excitatory amino acid release in rats with adjuvant-induced inflammation.

Journal: Anesthesia and analgesia 20020301

Title: Advances in topical glaucoma therapy.

Journal: Veterinary ophthalmology 20020301

Title: A comparison of the short-term hypotensive effects and side effects of unilateral brimonidine and apraclonidine in patients with elevated intraocular pressure.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20020101

Title: Cutaneous drug reaction case reports: from the world literature.

Journal: American journal of clinical dermatology 20020101

Title: Effects of acute topical administration of clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2% on visual field parameters and ocular perfusion pressure in patients with primary open-angle glaucoma.

Journal: Acta ophthalmologica Scandinavica. Supplement 20020101

Title: Allergic contact dermatitis from apraclonidine in eyedrops.

Journal: Contact dermatitis 20011001

Title: Potent alpha(2A)-adrenoceptor-mediated vasoconstriction by brimonidine in porcine ciliary arteries.

Journal: Investigative ophthalmology & visual science 20010801

Title: Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors.

Journal: Brain research 20010615

Title: Brimonidine 0.2% versus apraclonidine 0.5% for prevention of intraocular pressure elevations after anterior segment laser surgery.

Journal: Ophthalmology 20010601

Title: Differential effects of alpha-adrenoceptor agonists on human retinal microvessel diameter.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 20010601

Title: Immediate diode laser peripheral iridoplasty as treatment of acute attack of primary angle closure glaucoma: a preliminary study.

Journal: Journal of glaucoma 20010401

Title: [Reduction of ocular pulse amplitude by apraclonidine--prospective double-blind, randomized clinical trial with 10 subjects].

Journal: Klinische Monatsblatter fur Augenheilkunde 20010301

Title: Effectiveness of apraclonidine 1% in preventing intraocular pressure rise following macular hole surgery.

Journal: The British journal of ophthalmology 20010201

Title: Galanin/alpha2-adrenoceptor interactions in telencephalic and diencephalic regions of the rat.

Journal: Neuroreport 20010122

Title: Effects of alpha(2)-adrenergic agonists on lipopolysaccharide-induced aqueous flare elevation in pigmented rabbits.

Journal: Japanese journal of ophthalmology 20010101

Title: Distribution of alpha 2-adrenergic receptor binding in the developing human brain stem.

Journal: Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society 20010101

Title: The one-month effects of topical betaxolol, dorzolamide and apraclonidine on ocular blood flow velocities in patients with newly diagnosed primary open-angle glaucoma.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde 20010101

Title: [Iopidine in the control of intraocular pressure after glaucoma laser treatment].

Journal: Oftalmologia (Bucharest, Romania : 1990) 20010101

Title: [Glaucoma as primary optic neuropathy].

Journal: Oftalmologia (Bucharest, Romania : 1990) 20010101

Title: Galanin/alpha2-receptor interactions in central cardiovascular control.

Journal: Neuropharmacology 20000608

Title: Incidence of brimonidine allergy in patients previously allergic to apraclonidine.

Journal: Journal of glaucoma 20000601

Title: Reversal of intraocular pressure increases with 0.5% apraclonidine after dilated fundus examination in patients with chronic open-angle glaucoma.

Journal: Journal of the American Optometric Association 19990401

Title: Effects of topical administration of 0.5% apraclonidine on intraocular pressure, pupil size, and heart rate in clinically normal dogs.

Journal: American journal of veterinary research 19960101

Title: Evaluation of adverse reactions of aponidine hydrochloride ophthalmic solution.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics 19950101

Title: Agmatine: an endogenous clonidine-displacing substance in the brain.

Journal: Science (New York, N.Y.) 19940218

Title: Reformulation and drop size of apraclonidine hydrochloride.

Journal: American journal of ophthalmology 19920215

Title: Cardiovascular and intraocular pressure effects and plasma concentrations of apraclonidine.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 19900901

Title: Apraclonidine hydrochloride: an evaluation of plasma concentrations, and a comparison of its intraocular pressure lowering and cardiovascular effects to timolol maleate.

Journal: Transactions of the American Ophthalmological Society 19900101

Title: Wijemanne S, et al. Apraclonidine in the treatment of ptosis. J Neurol Sci. 2017;376:129‐132.

Title: Searles RV, et al. Aqueous humor dynamics in anesthetized rats infused with intracameral apraclonidine. Pharmacology. 1999;58(4):220‐226.

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SDS
Tags:73218-79-8 Molecular Formula|73218-79-8 MDL|73218-79-8 SMILES|73218-79-8 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride
Catalog No.: AA005FMP
73218-79-8,MFCD00135922
73218-79-8 | 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride
Pack Size: 1mg
Purity: 97%
in stock
$8.00 $6.00
Pack Size: 25mg
Purity: 97%
in stock
$61.00 $43.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA005FMP
Chemical Name: 2,6-Dichloro-N1-(4,5-dihydro-1H-imidazol-2-yl)benzene-1,4-diamine hydrochloride
CAS Number: 73218-79-8
Molecular Formula: C9H11Cl3N4
Molecular Weight: 281.5694
MDL Number: MFCD00135922
SMILES: Nc1cc(Cl)c(c(c1)Cl)NC1=NCCN1.Cl
Properties
Form: Solid  
MP: >2300C  
Solubility: 45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 1.4 mg/mL Solutions may be stored for several days at 4?#x00b0;C  
Storage: Inert atmosphere;Room Temperature;  
Complexity: 247  
Covalently-Bonded Unit Count: 2  
Heavy Atom Count: 16  
Hydrogen Bond Acceptor Count: 2  
Hydrogen Bond Donor Count: 4  
Rotatable Bond Count: 2  
Literature fold

Title: [Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].

Journal: Journal francais d'ophtalmologie20121001

Title: Hemifacial flushing after bathing and crying.

Journal: The Journal of pediatrics20120601

Title: Impact of T3 thoracoscopic sympathectomy on pupillary function: a cause of partial Horner's syndrome?

Journal: Surgical endoscopy20120401

Title: Pupillometry study of brimonidine tartrate 0.2% and apraclonidine 0.5%.

Journal: Journal of clinical pharmacology20111201

Title: [α-agonists in ophthalmology].

Journal: Pharmazie in unserer Zeit20111101

Title: Apraclonidine and my pupil.

Journal: Clinical autonomic research : official journal of the Clinical Autonomic Research Society20111001

Title: Early diagnosis of Horner syndrome using topical apraclonidine.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20110901

Title: Pharmacological diagnosis of Horner's syndrome in the emergency department.

Journal: Emergency medicine journal : EMJ20110801

Title: Confirmation of Horner's syndrome using apraclonidine eye drops.

Journal: Postgraduate medical journal20110601

Title: [Acquired Horner's syndrome].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke20110520

Title: Teaching NeuroImages: Positive apraclonidine test in Horner syndrome.

Journal: Neurology20110517

Title: Teaching NeuroImages: honeycomb appearance of the brain in a patient with Canavan disease.

Journal: Neurology20110329

Title: Horner's syndrome as a complication of percutaneous ethanol treatment of thyroid nodule.

Journal: Thyroid : official journal of the American Thyroid Association20110301

Title: [Prevention of intraocular pressure elevation after argon laser trabeculoplasty in primary open angle glaucoma].

Journal: Srpski arhiv za celokupno lekarstvo20110101

Title: Systemic effects of topical ophthalmic agents.

Journal: British journal of anaesthesia20100801

Title: Using apraclonidine in diagnosing Horner syndrome in children.

Journal: American journal of ophthalmology20100501

Title: Positive apraclonidine test 36 hours after acute onset of horner syndrome in dorsolateral pontomedullary stroke.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20100301

Title: [Unilateral allergic contact dermatitis of the eyelid caused by Iopimax].

Journal: Actas dermo-sifiliograficas20091201

Title: A pharmacologic pupillary test in the diagnosis of diabetic autonomic neuropathy.

Journal: Korean journal of ophthalmology : KJO20091201

Title: Current pharmacologic testing for Horner syndrome.

Journal: Current neurology and neuroscience reports20090901

Title: Possible effect of systemic sympathicolytic drugs on apraclonidine test.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie20090801

Title: Brimonidine and apraclonidine as vasoconstrictors in adjustable strabismus surgery.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus20090401

Title: False-negative apraclonidine testing in acute Horner syndrome.

Journal: Canadian journal of ophthalmology. Journal canadien d'ophtalmologie20090201

Title: [Usefulness of apraclonidine in the diagnosis of Horner syndrome].

Journal: Archivos de la Sociedad Espanola de Oftalmologia20090201

Title: Exposure to topical apraclonidine in children with glaucoma.

Journal: Journal of glaucoma20090101

Title: Topical apraclonidine to diagnose Bernard-Horner syndrome.

Journal: Bulletin de la Societe belge d'ophtalmologie20090101

Title: Recurrent serous macular detachment after topical ocular hypotensive medication.

Journal: Clinical & experimental optometry20081101

Title: Positive apraclonidine test within two weeks of onset of Horner syndrome caused by carotid artery dissection.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20080901

Title: Pupillary autonomic neuropathy simulating partial Horner syndrome in diabetes mellitus and its reversal with control of blood glucose.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20080901

Title: False negative apraclonidine test in two patients with Horner syndrome.

Journal: Klinische Monatsblatter fur Augenheilkunde20080501

Title: Central alpha-2 adrenergic eye drops: case series of 3 pediatric systemic poisonings.

Journal: Pediatric emergency care20080301

Title: The pupil.

Journal: Current opinion in neurology20080201

Title: Use of 0.5% apraclonidine solution in evaluation of blepharoptosis.

Journal: Ophthalmic plastic and reconstructive surgery20080101

Title: The acute morphologic changes that occur at the optic nerve head induced by medical reduction of intraocular pressure.

Journal: Journal of glaucoma20070901

Title: Apraclonidine in the diagnosis of Horner's syndrome.

Journal: South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde20070701

Title: Adverse effects of apraclonidine used in the diagnosis of Horner syndrome in infants.

Journal: Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus20070601

Title: Pharmacologic reversal of Horner's syndrome-related ptosis with apraclonidine.

Journal: Ear, nose, & throat journal20070501

Title: Corneal thickness- and age-related biomechanical properties of the cornea measured with the ocular response analyzer.

Journal: Investigative ophthalmology & visual science20061201

Title: Topical apraclonidine testing of pupillary sympathetic denervation in diabetic patients.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20061201

Title: Congenital Horner's syndrome and the usefulness of the apraclonidine test in its diagnosis.

Journal: Indian journal of ophthalmology20060901

Title: Brinzolamide 1% versus apraclonidine 0.5% to prevent intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.

Journal: Journal of cataract and refractive surgery20060901

Title: Efficacy of apraclonidine 0.5% in the diagnosis of Horner syndrome in pediatric patients under low or high illumination.

Journal: American journal of ophthalmology20060901

Title: The effect of topical apraclonidine on subconjunctival hemorrhage and flap adherence in LASIK patients.

Journal: Journal of refractive surgery (Thorofare, N.J. : 1995)20060601

Title: Comparing efficacies of 0.5% apraclonidine with 4% cocaine in the diagnosis of horner syndrome in pediatric patients.

Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics20060601

Title: Reduction of anterior-segment vascularity with preoperative topical apraclonidine 1%.

Journal: Journal of cataract and refractive surgery20060401

Title: Topical apraclonidine testing discloses pupillary sympathetic denervation in diabetic patients.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20060301

Title: Effect of 0.5% apraclonidine on ptosis in Horner syndrome.

Journal: Ophthalmic plastic and reconstructive surgery20060101

Title: Comparative efficacy of acetazolamide and apraclonidine in the control of intraocular pressure following phacoemulsification.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde20060101

Title: Apraclonidine and LASIK.

Journal: Ophthalmology20051201

Title: The sensitivity and specificity of 0.5% apraclonidine in the diagnosis of oculosympathetic paresis.

Journal: The British journal of ophthalmology20051101

Title: More than just an ocular solution.

Journal: Emergency medicine journal : EMJ20051001

Title: Brimonidine 0.15% versus apraclonidine 0.5% for prevention of intraocular pressure elevation after anterior segment laser surgery.

Journal: Journal of cataract and refractive surgery20050901

Title: Are we ready to replace cocaine with apraclonidine in the pharmacologic diagnosis of Horner syndrome?

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20050601

Title: Topical apraclonidine in the diagnosis of suspected Horner syndrome.

Journal: Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society20050601

Title: The utility of 0.5% apraclonidine in the diagnosis of horner syndrome.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20050401

Title: The use of apraclonidine eyedrops to treat ptosis after the administration of botulinum toxin to the upper face.

Journal: Dermatology online journal20050301

Title: Treatment of ptosis as a complication of botulinum toxin injection.

Journal: Pain medicine (Malden, Mass.)20050101

Title: Comparing brimonidine 0.2% to apraclonidine 1.0% in the prevention of intraocular pressure elevation and their pupillary effects following laser peripheral iridotomy.

Journal: Japanese journal of ophthalmology20050101

Title: Effect of apraclonidine versus dorzolamide on intraocular pressure after phacoemulsification.

Journal: Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye20050101

Title: Neodymium:yttrium-aluminum-garnet capsulotomy and intraocular pressure in pseudophakic patients with glaucoma.

Journal: Ophthalmology20040701

Title: The effect of alpha2-agonist on IOP rise following Nd-YAG laser iridotomy.

Journal: The Tokai journal of experimental and clinical medicine20040401

Title: The use of apraclonidine in the diagnosis of horner syndrome in pediatric patients.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20040201

Title: Double-blind parallel comparison of multiple doses of apraclonidine, clonidine, and placebo administered intra-articularly to patients undergoing arthroscopic knee surgery.

Journal: The Clinical journal of pain20040101

Title: The utility of 0.5% apraclonidine in the diagnosis of horner syndrome.

Journal: Archives of ophthalmology (Chicago, Ill. : 1960)20030801

Title: The effect of topical glaucoma medications evaluated by perimetry.

Journal: The British journal of ophthalmology20030601

Title: Ocular perfusion pressure and visual field indice modifications induced by alpha-agonist compound (clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2%) topical administration. An acute study on primary open-angle glaucoma patients.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde20030101

Title: Preventing intraocular pressure increase after phacoemulsification and the role of perioperative apraclonidine.

Journal: Journal of cataract and refractive surgery20021201

Title: Dorzolamide X apraclonidine in the prevention of the intraocular pressure spike after Nd : YAG laser posterior capsulotomy.

Journal: Current eye research20021001

Title: Effects of topical antiglaucoma eye drops on prostaglandin E(2)-induced aqueous flare elevation in pigmented rabbits.

Journal: Investigative ophthalmology & visual science20020401

Title: Apraclonidine attenuates the increases in spinal excitatory amino acid release in rats with adjuvant-induced inflammation.

Journal: Anesthesia and analgesia20020301

Title: Advances in topical glaucoma therapy.

Journal: Veterinary ophthalmology20020301

Title: A comparison of the short-term hypotensive effects and side effects of unilateral brimonidine and apraclonidine in patients with elevated intraocular pressure.

Journal: Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift fur Augenheilkunde20020101

Title: Cutaneous drug reaction case reports: from the world literature.

Journal: American journal of clinical dermatology20020101

Title: Effects of acute topical administration of clonidine 0.125%, apraclonidine 1.0% and brimonidine 0.2% on visual field parameters and ocular perfusion pressure in patients with primary open-angle glaucoma.

Journal: Acta ophthalmologica Scandinavica. Supplement20020101

Title: Allergic contact dermatitis from apraclonidine in eyedrops.

Journal: Contact dermatitis20011001

Title: Potent alpha(2A)-adrenoceptor-mediated vasoconstriction by brimonidine in porcine ciliary arteries.

Journal: Investigative ophthalmology & visual science20010801

Title: Topically applied clonidine protects the rat retina from ischaemia/reperfusion by stimulating alpha(2)-adrenoceptors and not by an action on imidazoline receptors.

Journal: Brain research20010615

Title: Brimonidine 0.2% versus apraclonidine 0.5% for prevention of intraocular pressure elevations after anterior segment laser surgery.

Journal: Ophthalmology20010601

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Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics20010601

Title: Immediate diode laser peripheral iridoplasty as treatment of acute attack of primary angle closure glaucoma: a preliminary study.

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Title: Effectiveness of apraclonidine 1% in preventing intraocular pressure rise following macular hole surgery.

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