75706-12-6,MFCD00867593
Catalog No.:AA005IR9

75706-12-6 | Leflunomide

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98%
in stock  
$6.00   $4.00
- +
10mg
98%
in stock  
$8.00   $6.00
- +
100mg
98%
in stock  
$21.00   $15.00
- +
250mg
98%
in stock  
$37.00   $26.00
- +
1g
98%
in stock  
$75.00   $53.00
- +
5g
98%
in stock  
$228.00   $160.00
- +
25g
98%
in stock  
$633.00   $444.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA005IR9
Chemical Name:
Leflunomide
CAS Number:
75706-12-6
Molecular Formula:
C12H9F3N2O2
Molecular Weight:
270.2073
MDL Number:
MFCD00867593
SMILES:
O=C(c1cnoc1C)Nc1ccc(cc1)C(F)(F)F
Properties
Properties
 
BP:
289.3°C at 760 mmHg  
Form:
Solid  
MP:
153-156°C  
Storage:
Keep in dry area;Room Temperature;  

Computed Properties
 
Complexity:
327  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
19  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
XLogP3:
2.5  

Literature

Title: Davis JP, et al. The immunosuppressive metabolite of leflunomide is a potent inhibitor of human dihydroorotate dehydrogenase. Biochemistry. 1996 Jan 30;35(4):1270-3.

Title: Xu X, et al. Inhibition of protein tyrosine phosphorylation in T cells by a novel immunosuppressive agent, leflunomide. J Biol Chem. 1995 May 26;270(21):12398-403.

Title: Fox RI, et al. Mechanism of action for leflunomide in rheumatoid arthritis. Clin Immunol. 1999 Dec;93(3):198-208.

Quotation Request
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SDS
Tags:75706-12-6 Molecular Formula|75706-12-6 MDL|75706-12-6 SMILES|75706-12-6 Leflunomide
Catalog No.: AA005IR9
75706-12-6,MFCD00867593
75706-12-6 | Leflunomide
Pack Size: 1mg
Purity: 98%
in stock
$6.00 $4.00
Pack Size: 10mg
Purity: 98%
in stock
$8.00 $6.00
Pack Size: 100mg
Purity: 98%
in stock
$21.00 $15.00
Pack Size: 250mg
Purity: 98%
in stock
$37.00 $26.00
Pack Size: 1g
Purity: 98%
in stock
$75.00 $53.00
Pack Size: 5g
Purity: 98%
in stock
$228.00 $160.00
Pack Size: 25g
Purity: 98%
in stock
$633.00 $444.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA005IR9
Chemical Name: Leflunomide
CAS Number: 75706-12-6
Molecular Formula: C12H9F3N2O2
Molecular Weight: 270.2073
MDL Number: MFCD00867593
SMILES: O=C(c1cnoc1C)Nc1ccc(cc1)C(F)(F)F
Properties
BP: 289.3°C at 760 mmHg  
Form: Solid  
MP: 153-156°C  
Storage: Keep in dry area;Room Temperature;  
Complexity: 327  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 19  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 1  
Rotatable Bond Count: 2  
XLogP3: 2.5  
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