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74563-64-7,MFCD00129085
Catalog No.:AA005JAH

74563-64-7 | Phytantriol

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200mg
>95.0%(GC)
in stock  
$93.00   $65.00
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1g
>95.0%(GC)
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$195.00   $137.00
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5g
>95.0%(GC)
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005JAH
Chemical Name:
Phytantriol
CAS Number:
74563-64-7
Molecular Formula:
C20H42O3
Molecular Weight:
330.5457
MDL Number:
MFCD00129085
SMILES:
OCC(C(CCCC(CCCC(CCCC(C)C)C)C)(O)C)O
Properties
Properties
 
BP:
394.3°C at 760 mmHg  
Form:
Liquid  
MP:
56-57°  
Refractive Index:
n20/D 1.47(lit.)  
Storage:
Room Temperature;Inert atmosphere;  

Computed Properties
 
Complexity:
280  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
3  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
14  
Undefined Atom Stereocenter Count:
4  
XLogP3:
5.9  

Downstream Synthesis Route

[1]Suzuki,Shigeaki;Fujita,Yoshiji;Kobayashi,Yuichi;Sato,Fumie[TetrahedronLetters,1986,vol.27,#1,p.69-70]

[1]Suzuki,Shigeaki;Fujita,Yoshiji;Kobayashi,Yuichi;Sato,Fumie[TetrahedronLetters,1986,vol.27,#1,p.69-70]

[1]Suzuki,Shigeaki;Fujita,Yoshiji;Kobayashi,Yuichi;Sato,Fumie[TetrahedronLetters,1986,vol.27,#1,p.69-70]

Literature

Title: Characterization of oil-free and oil-loaded liquid-crystalline particles stabilized by negatively charged stabilizer citrem.

Journal: Langmuir : the ACS journal of surfaces and colloids 20120814

Title: Horse heart cytochrome c entrapped into the hydrated liquid-crystalline phases of phytantriol: X-ray diffraction and Raman spectroscopic characterization.

Journal: Journal of colloid and interface science 20120715

Title: High-throughput discovery of novel steric stabilizers for cubic lyotropic liquid crystal nanoparticle dispersions.

Journal: Langmuir : the ACS journal of surfaces and colloids 20120626

Title: Metal-free and MRI visible theranostic lyotropic liquid crystal nitroxide-based nanoparticles.

Journal: Biomaterials 20120301

Title: Revisiting β-casein as a stabilizer for lipid liquid crystalline nanostructured particles.

Journal: Langmuir : the ACS journal of surfaces and colloids 20111220

Title: Evaluating the link between self-assembled mesophase structure and drug release.

Journal: International journal of pharmaceutics 20111212

Title: Preparation of phytantriol cubosomes by solvent precursor dilution for the delivery of protein vaccines.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110901

Title: Nanostructured liquid crystalline particles provide long duration sustained-release effect for a poorly water soluble drug after oral administration.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20110730

Title: Transarterial chemoembolization using docetaxel-loaded phytantriol cubic phase precursor for the treatment of hepatocellular carcinoma.

Journal: Journal of pharmaceutical sciences 20110601

Title: Adsorption of nonlamellar nanostructured liquid-crystalline particles to biorelevant surfaces for improved delivery of bioactive compounds.

Journal: ACS applied materials & interfaces 20110501

Title: Transfer of lipid and phase reorganisation in self-assembled liquid crystal nanostructured particles based on phytantriol.

Journal: Physical chemistry chemical physics : PCCP 20110227

Title: Phytantriol-based inverted type bicontinuous cubic phase for vascular embolization and drug sustained release.

Journal: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 20101223

Title: The influence of dipalmitoyl phosphatidylserine on phase behaviour of and cellular response to lyotropic liquid crystalline dispersions.

Journal: Biomaterials 20101201

Title: High throughput preparation and characterisation of amphiphilic nanostructured nanoparticulate drug delivery vehicles.

Journal: International journal of pharmaceutics 20100816

Title: Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water soluble drugs I. Phase behaviour in physiologically-relevant media.

Journal: The Journal of pharmacy and pharmacology 20100701

Title: Phytantriol and glyceryl monooleate cubic liquid crystalline phases as sustained-release oral drug delivery systems for poorly water-soluble drugs II. In-vivo evaluation.

Journal: The Journal of pharmacy and pharmacology 20100701

Title: Drug release from lipid liquid crystalline phases: relation with phase behavior.

Journal: Drug development and industrial pharmacy 20100401

Title: Fragrance material review on 2-hexadecen-1-ol, 3,7,11,15-tetramethyl.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 20100101

Title: Liquid crystalline systems of phytantriol and glyceryl monooleate containing a hydrophilic protein: Characterisation, swelling and release kinetics.

Journal: Journal of pharmaceutical sciences 20091101

Title: Stimuli responsive liquid crystals provide 'on-demand' drug delivery in vitro and in vivo.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20090505

Title: Interaction between lamellar (vesicles) and nonlamellar lipid liquid-crystalline nanoparticles as studied by time-resolved small-angle X-ray diffraction.

Journal: Langmuir : the ACS journal of surfaces and colloids 20090407

Title: Positron annihilation lifetime spectroscopy (PALS) as a characterization technique for nanostructured self-assembled amphiphile systems.

Journal: The journal of physical chemistry. B 20090108

Title: Nanostructure of liquid crystalline matrix determines in vitro sustained release and in vivo oral absorption kinetics for hydrophilic model drugs.

Journal: International journal of pharmaceutics 20090105

Title: Allergic contact dermatitis to phytantriol.

Journal: Contact dermatitis 20081001

Title: Lipid cubic phases in topical drug delivery: visualization of skin distribution using two-photon microscopy.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20080807

Title: Impurities in commercial phytantriol significantly alter its lyotropic liquid-crystalline phase behavior.

Journal: Langmuir : the ACS journal of surfaces and colloids 20080601

Title: Thermomyces lanuginosus lipase in the liquid-crystalline phases of aqueous phytantriol: X-ray diffraction and vibrational spectroscopic studies.

Journal: Biophysical chemistry 20080501

Title: Aqueous self-assembly of phytantriol in ternary systems: effect of monoolein, distearoylphosphatidylglycerol and three water-miscible solvents.

Journal: Journal of colloid and interface science 20071115

Title: Characterisation of bicontinuous cubic liquid crystalline systems of phytantriol and water using cryo field emission scanning electron microscopy (cryo FESEM).

Journal: Micron (Oxford, England : 1993) 20070101

Title: Final report on the safety assessment of phytantriol.

Journal: International journal of toxicology 20070101

Title: Biofunctionalized surfactant mesophases as polyvalent inhibitors of cholera toxin.

Journal: Bioconjugate chemistry 20070101

Title: Bulk and dispersed aqueous phase behavior of phytantriol: effect of vitamin E acetate and F127 polymer on liquid crystal nanostructure.

Journal: Langmuir : the ACS journal of surfaces and colloids 20061107

Title: Anisotropic surface melting in lyotropic cubic crystals: part 2: facet-by-facet melting at Ia3d/vapor interfaces.

Journal: The European physical journal. E, Soft matter 20060501

Title: Infrared and Raman bands of phytantriol as markers of hydrogen bonding and interchain interaction.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20051201

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