Title: Suppressive effects of antimycotics on thymic stromal lymphopoietin production in human keratinocytes.
Journal: Journal of dermatological science20130901
Title: Helenalin-induced apoptosis is dependent on production of reactive oxygen species and independent of induction of endoplasmic reticulum stress in renal cell carcinoma.
Journal: Toxicology in vitro : an international journal published in association with BIBRA20130301
Title: Enantiomeric derivatives of tokinolide B: absolute configuration and biological properties.
Journal: Journal of natural products20120525
Title: Supercritical fluid extraction assisted isolation of sesquiterpene lactones with antiproliferative effects from Centipeda minima.
Journal: Phytochemistry20120401
Title: NF-κB p65 repression by the sesquiterpene lactone, Helenalin, contributes to the induction of autophagy cell death.
Journal: BMC complementary and alternative medicine20120101
Title: Helenalin bypasses Bcl-2-mediated cell death resistance by inhibiting NF-κB and promoting reactive oxygen species generation.
Journal: Biochemical pharmacology20110901
Title: Activation and induction of cytosolic phospholipase A2 by TNF-α mediated through Nox2, MAPKs, NF-κB, and p300 in human tracheal smooth muscle cells.
Journal: Journal of cellular physiology20110801
Title: Quantitative analysis of sesquiterpene lactones in extract of Arnica montana L. by 1H NMR spectroscopy.
Journal: Journal of pharmaceutical and biomedical analysis20110105
Title: Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways.
Journal: Journal of neuroinflammation20110101
Title: Surface plasmon resonance analysis of nuclear factor-kappaB protein interactions with the sesquiterpene lactone helenalin.
Journal: Analytical biochemistry20100601
Title: Discovery and development of natural product-derived chemotherapeutic agents based on a medicinal chemistry approach.
Journal: Journal of natural products20100326
Title: Dibenzylbutyrolactone lignans from Forsythia koreana fruits attenuate lipopolysaccharide-induced inducible nitric oxide synthetase and cyclooxygenase-2 expressions through activation of nuclear factor-κb and mitogen-activated protein kinase in RAW264.7 cells.
Journal: Biological & pharmaceutical bulletin20100101
Title: Helenalin suppresses essential immune functions of activated CD4+ T cells by multiple mechanisms.
Journal: Molecular immunology20090901
Title: Dimethylfumarate inhibits NF-{kappa}B function at multiple levels to limit airway smooth muscle cell cytokine secretion.
Journal: American journal of physiology. Lung cellular and molecular physiology20090801
Title: Effects of hyaluronan oligosaccharide on the expression of MMP-1 in periodontal ligament cells.
Journal: Archives of oral biology20090801
Title: Overexpression of HO-1 protects against TNF-alpha-mediated airway inflammation by down-regulation of TNFR1-dependent oxidative stress.
Journal: The American journal of pathology20090801
Title: Sesquiterpene lactones in Arnica montana: helenalin and dihydrohelenalin chemotypes in Spain.
Journal: Planta medica20090501
Title: Cigarette smoke extract induces cytosolic phospholipase A2 expression via NADPH oxidase, MAPKs, AP-1, and NF-kappaB in human tracheal smooth muscle cells.
Journal: Free radical biology & medicine20090401
Title: Helenalin-mediated post-transcriptional regulation of p21(Cip1) inhibits 3T3-L1 preadipocyte proliferation.
Journal: Journal of cellular biochemistry20081015
Title: Use of self-organizing maps and molecular descriptors to predict the cytotoxic activity of sesquiterpene lactones.
Journal: European journal of medicinal chemistry20081001
Title: Natural sesquiterpene lactones are active against Leishmania mexicana.
Journal: The Journal of parasitology20081001
Title: Inhibition of Nod2 signaling and target gene expression by curcumin.
Journal: Molecular pharmacology20080701
Title: Neural networks as valuable tools to differentiate between sesquiterpene lactones' inhibitory activity on serotonin release and on NF-kappaB.
Journal: Journal of medicinal chemistry20080313
Title: Effect of vehicles on topical application of aloe vera and arnica montana components.
Journal: Drug delivery20071001
Title: The effect of 17beta-estradiol on IL-6 secretion and NF-kappaB DNA-binding activity in human retinal pigment epithelial cells.
Journal: Immunology letters20070615
Title: Withaferin a strongly elicits IkappaB kinase beta hyperphosphorylation concomitant with potent inhibition of its kinase activity.
Journal: The Journal of biological chemistry20070216
Title: The autocrine TNFalpha signalling loop in keratinocytes requires atypical PKC species and NF-kappaB activation but is independent of cholesterol-enriched membrane microdomains.
Journal: Biochemical pharmacology20070215
Title: Helenalin reduces Staphylococcus aureus infection in vitro and in vivo.
Journal: Veterinary microbiology20070131
Title: Skin penetration behaviour of sesquiterpene lactones from different Arnica preparations using a validated GC-MSD method.
Journal: Journal of pharmaceutical and biomedical analysis20070104
Title: Sesquiterpene lactone helenalin suppresses Leydig and adrenocortical cell steroidogenesis by inhibiting expression of the steroidogenic acute regulatory protein.
Journal: Reproductive toxicology (Elmsford, N.Y.)20061101
Title: Novel effect of helenalin on Akt signaling and Skp2 expression in 3T3-L1 preadipocytes.
Journal: Biochemical and biophysical research communications20060721
Title: Inhibition of homodimerization of Toll-like receptor 4 by curcumin.
Journal: Biochemical pharmacology20060628
Title: BLIMP-1 is a target of cellular stress and downstream of the unfolded protein response.
Journal: European journal of immunology20060601
Title: Development and stability of semisolid preparations based on a supercritical CO2 Arnica extract.
Journal: Journal of pharmaceutical and biomedical analysis20060503
Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.
Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501
Title: Nuclear factor-kappaB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats.
Journal: Brain research20060407
Title: Development of a structural model for NF-kappaB inhibition of sesquiterpene lactones using self-organizing neural networks.
Journal: Journal of medicinal chemistry20060406
Title: Transcriptional regulation of VCAM-1 expression by tumor necrosis factor-alpha in human tracheal smooth muscle cells: involvement of MAPKs, NF-kappaB, p300, and histone acetylation.
Journal: Journal of cellular physiology20060401
Title: TNF-alpha-induced optic nerve degeneration and nuclear factor-kappaB p65.
Journal: Investigative ophthalmology & visual science20060401
Title: Delayed radioprotection by nuclear transcription factor kappaB -mediated induction of manganese superoxide dismutase in human microvascular endothelial cells after exposure to the free radical scavenger WR1065.
Journal: Free radical biology & medicine20060315
Title: Involvement of Nrf2, p38, B-Raf, and nuclear factor-kappaB, but not phosphatidylinositol 3-kinase, in induction of hemeoxygenase-1 by dietary polyphenols.
Journal: Molecular pharmacology20060301
Title: NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.
Journal: The Journal of biological chemistry20060127
Title: BK-induced cytosolic phospholipase A2 expression via sequential PKC-delta, p42/p44 MAPK, and NF-kappaB activation in rat brain astrocytes.
Journal: Journal of cellular physiology20060101
Title: Synthesis and anti-viral activity of a series of sesquiterpene lactones and analogues in the subgenomic HCV replicon system.
Journal: Bioorganic & medicinal chemistry20060101
Title: Potent inhibition of human telomerase by helenalin.
Journal: Cancer letters20050928
Title: Polysaccharide purified from Ganoderma lucidum induced activation and maturation of human monocyte-derived dendritic cells by the NF-kappaB and p38 mitogen-activated protein kinase pathways.
Journal: Journal of leukocyte biology20050801
Title: Activation of nuclear factor-kappaB contributes to induction of death receptors and apoptosis by the synthetic retinoid CD437 in DU145 human prostate cancer cells.
Journal: Cancer research20050715
Title: Apoptosis induction by a novel retinoid-related molecule requires nuclear factor-kappaB activation.
Journal: Cancer research20050601
Title: Induction of human leukemia HL-60 cell differentiation via a PKC/ERK pathway by helenalin, a pseudoguainolide sesquiterpene lactone.
Journal: European journal of pharmacology20050328
Title: Involvement of p42/p44 MAPK, JNK, and NF-kappaB in IL-1beta-induced ICAM-1 expression in human pulmonary epithelial cells.
Journal: Journal of cellular physiology20050201
Title: The trypanocidal effect of sesquiterpene lactones helenalin and mexicanin on cultured epimastigotes.
Journal: The Journal of parasitology20050201
Title: Intracellular signalings underlying bradykinin-induced matrix metalloproteinase-9 expression in rat brain astrocyte-1.
Journal: Cellular signalling20041001
Title: New chromanone acids with antibacterial activity from Calophyllum brasiliense.
Journal: Journal of natural products20040401
Title: Pseudoguaianolide sesquiterpene lactones with high activities against the human malaria parasite Plasmodium falciparum.
Journal: Phytotherapy research : PTR20040201
Title: Influence of helenanolide-type sesquiterpene lactones on gene transcription profiles in Jurkat T cells and human peripheral blood cells: anti-inflammatory and cytotoxic effects.
Journal: Biochemical pharmacology20031201
Title: Regulation of microglial inflammatory response by histone deacetylase inhibitors.
Journal: Journal of neurochemistry20031001
Title: Characterization of the molecular events following impairment of NF-kappaB-driven transcription in neurons.
Journal: Brain research. Molecular brain research20021230
Title: Anti-trypanosomal activity of helenalin and some structurally related sesquiterpene lactones.
Journal: Planta medica20020801
Title: Inhibitory effects of helenalin and related compounds on 5-lipoxygenase and leukotriene C(4) synthase in human blood cells.
Journal: Biochemical pharmacology20011001
Title: Helenalin triggers a CD95 death receptor-independent apoptosis that is not affected by overexpression of Bcl-x(L) or Bcl-2.
Journal: Cancer research20010801
Title: The influence of glutathione and cysteine levels on the cytotoxicity of helenanolide type sesquiterpene lactones against KB cells.
Journal: Bioorganic & medicinal chemistry20010801
