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Home Other Building Blocks 78967-07-4
78967-07-4,MFCD00712149
Catalog No.:AA005O4G

78967-07-4 | Mofezolac

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
in stock  
$7.00   $5.00
- +
5mg
95%
in stock  
$21.00   $15.00
- +
10mg
95%
in stock  
$35.00   $25.00
- +
25mg
95%
in stock  
$68.00   $48.00
- +
50mg
95%
in stock  
$116.00   $82.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005O4G
Chemical Name:
Mofezolac
CAS Number:
78967-07-4
Molecular Formula:
C19H17NO5
Molecular Weight:
339.3420
MDL Number:
MFCD00712149
SMILES:
COc1ccc(cc1)c1c(onc1c1ccc(cc1)OC)CC(=O)O
Properties
Properties
 
BP:
527.2°C at 760 mmHg  
Form:
Solid  
MP:
147.5℃  
Storage:
Keep in dry area;2-8℃;  


Downstream Synthesis Route

[1]ChemicalandPharmaceuticalBulletin,1988,vol.36,p.3142-3146

[1]ChemicalandPharmaceuticalBulletin,1988,vol.36,p.3142-3146

[2]Patent:WO2014/115020,2014,A1.Locationinpatent:Page/Pagecolumn8;14

[3]ChemicalandPharmaceuticalBulletin,1988,vol.36,p.3142-3146

[1]ChemicalandPharmaceuticalBulletin,1988,vol.36,p.3142-3146

[1]ChemicalandPharmaceuticalBulletin,1988,vol.36,p.3142-3146

78967-07-4   
3-(4-Methoxy-phenyl)-5-methyl-4-4-(tetrahydro-pyran-2-yloxy)-phenyl-isoxazole 

[1]ChemicalandPharmaceuticalBulletin,1988,vol.36,p.3142-3146

Literature

Title: K Goto, et al. Analgesic effect of mofezolac, a non-steroidal anti-inflammatory drug, against phenylquinone-induced acute pain in mice. Prostaglandins Other Lipid Mediat. 1998 Jul;56(4):245-54.

Title: Maria Laura Pati, et al. Translational impact of novel widely pharmacological characterized mofezolac-derived COX-1 inhibitors combined with bortezomib on human multiple myeloma cell lines viability. Eur J Med Chem. 2019 Feb 15;164:59-76.

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