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76946-27-5,MFCD01249587
Catalog No.:AA005RP1

76946-27-5 | 2-(Methoxymethyl)pyrrolidine

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1g
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in stock  
$103.00   $73.00
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5g
95%
in stock  
$361.00   $253.00
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10g
95%
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$618.00   $433.00
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25g
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$1,258.00   $881.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA005RP1
Chemical Name:
2-(Methoxymethyl)pyrrolidine
CAS Number:
76946-27-5
Molecular Formula:
C6H13NO
Molecular Weight:
115.1735
MDL Number:
MFCD01249587
SMILES:
COCC1CCCN1
NSC Number:
305701
Properties
Properties
 
BP:
141.9 °C at 760 mmHg  
Storage:
2-8℃;  

Computed Properties
 
Complexity:
65.5  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
8  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
2  
Undefined Atom Stereocenter Count:
1  
XLogP3:
0.2  

Downstream Synthesis Route

[1]Nijhuis,W.H.N.;Verboom,W.;Harkema,S.;Reinhoudt,D.N.[RecueildesTravauxChimiquesdesPays-Bas,1989,vol.108,#4,p.147-160]

[1]Patent:US2013/109661,2013,A1.Locationinpatent:Paragraph0400-0401

[2]Patent:WO2013/64445,2013,A1.Locationinpatent:Page/Pagecolumn98

76946-27-5    165803-94-1   
methyl5-formyl-2-(2-(methoxymethyl)pyrrolidin-1-yl)benzoate 

[1]CurrentPatentAssignee:AMGENINC-WO2016/16316,2016,A1Locationinpatent:Page/Pagecolumn116;117

14625-39-9    76946-27-5   
2-((2-(methoxymethyl)pyrrolidin-1-yl)methyl)-5-nitro-1H-benzodimidazole 

[1]Moustakim,Moses;Christott,Thomas;Monteiro,OctoviaP.;Bennett,James;Giroud,Charline;Ward,Jennifer;Rogers,CatherineM.;Smith,Paul;Panagakou,Ioanna;Díaz-Sáez,Laura;Felce,SuetLing;Gamble,Vicki;Gileadi,Carina;Halidi,Nadia;Heidenreich,David;Chaikuad,Apirat;Knapp,Stefan;Huber,KilianV.M.;Farnie,Gillian;Heer,Jag;Manevski,Nenad;Poda,Gennady;Al-awar,Rima;Dixon,DarrenJ.;Brennan,PaulE.;Fedorov,Oleg[AngewandteChemie-InternationalEdition,2018,vol.57,#50,p.16302-16307][Angew.Chem.,2018,vol.130,#50,p.16540-16545,6]

Literature

Title: Diastereoselective synthesis of N-secondary alkyl 2-alkoxymethylpyrrolidines via sequential addition reactions of organolithium and -magnesium reagents to N-thioformyl 2-alkoxymethylpyrrolidines.

Journal: The Journal of organic chemistry 20081205

Title: Water-soluble calix[4]resorcinarenes with hydroxyproline groups as chiral NMR solvating agents.

Journal: The Journal of organic chemistry 20080404

Title: The remarkable effect of the 7-substituent in the diastereoselective oxidative rearrangement of indoles: asymmetric synthesis of 3,3-disubstituted oxindoles.

Journal: Chemical communications (Cambridge, England) 20070121

Title: 5-pyrrolidinylsulfonyl isatins as a potential tool for the molecular imaging of caspases in apoptosis.

Journal: Journal of medicinal chemistry 20061116

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Tags:76946-27-5 Molecular Formula|76946-27-5 MDL|76946-27-5 SMILES|76946-27-5 2-(Methoxymethyl)pyrrolidine