Title: In Utero Exposure to a Cardiac Teratogen Causes Reversible Deficits in Postnatal Cardiovascular Function, But Altered Adaptation to the Burden of Pregnancy.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20151101
Title: Maternal rat serum concentrations of dimethadione do not explain intra-litter differences in the incidence of dimethadione-induced birth defects, including novel findings in foetal lung.
Journal: Toxicology 20141204
Title: In utero dimethadione exposure causes postnatal disruption in cardiac structure and function in the rat.
Journal: Toxicological sciences : an official journal of the Society of Toxicology 20141201
Title: Benzimidazolones: a new class of selective peroxisome proliferator-activated receptor γ (PPARγ) modulators.
Journal: Journal of medicinal chemistry 20111222
Title: Co-variation in frequency and severity of cardiovascular and skeletal defects in Sprague-Dawley rats after maternal administration of dimethadione, the N-demethylated metabolite of trimethadione.
Journal: Birth defects research. Part B, Developmental and reproductive toxicology 20110601
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Alterations in mouse embryo intracellular pH by DMO during culture impair implantation and fetal growth.
Journal: Reproductive biomedicine online 20100801
Title: Acidic and basic solutions dissolve protein plugs made of lithostathine complicating choledochal cyst/pancreaticobiliary maljunction.
Journal: Digestive diseases and sciences 20090701
Title: Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures.
Journal: Neuropsychiatric disease and treatment 20090101
Title: Glucose loading precipitates focal lactic acidosis in the vulnerable medial thalamus of thiamine-deficient rats.
Journal: Metabolic brain disease 20080301
Title: Polytherapy with hERG-blocking antiepileptic drugs: increased risk for embryonic cardiac arrhythmia and teratogenicity.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20070801
Title: Embryonic cardiac arrhythmia and generation of reactive oxygen species: common teratogenic mechanism for IKr blocking drugs.
Journal: Reproductive toxicology (Elmsford, N.Y.) 20070701
Title: Pharmacological evidence that stalk cell differentiation involves increases in the intracellular Ca(2+) and H(+) concentrations in Dictyostelium discoideum.
Journal: Development, growth & differentiation 20070401
Title: Thoracic skeletal defects and cardiac malformations: a common epigenetic link?
Journal: Birth defects research. Part C, Embryo today : reviews 20061201
Title: Interactive effects of cadmium and all-trans-retinoic acid on the induction of forelimb ectrodactyly in C57BL/6 mice.
Journal: Birth defects research. Part A, Clinical and molecular teratology 20060101
Title: Discriminative power of an assay for automated in vitro screening of teratogens.
Journal: Toxicology in vitro : an international journal published in association with BIBRA 20040801
Title: Disruption of bovine oocytes and preimplantation embryos by urea and acidic pH.
Journal: Journal of dairy science 20030401
Title: Embryonic arrhythmia by inhibition of HERG channels: a common hypoxia-related teratogenic mechanism for antiepileptic drugs?
Journal: Epilepsia 20020501
Title: Selection of test chemicals for the ECVAM international validation study on in vitro embryotoxicity tests. European Centre for the Validation of Alternative Methods.
Journal: Alternatives to laboratory animals : ATLA 20020101
Title: The clinical importance of the trimethadione tolerance test as a method for quantitative assessment of hepatic functional reserve in patients with biliary atresia.
Journal: Journal of clinical pharmacy and therapeutics 20011201
Title: Na(+)-dependent pH regulation by the amitochondriate protozoan parasite Giardia intestinalis.
Journal: The Journal of biological chemistry 20010803
Title: Altering intracellular pH disrupts development and cellular organization in preimplantation hamster embryos.
Journal: Biology of reproduction 20010601
Title: Trimethadione N-demethylation by rat liver CYP2E1 in vitro.
Journal: Research communications in molecular pathology and pharmacology 19960701
Title: Effects of the oxazolidinedione anticonvulsants trimethadione and dimethadione and the barbiturate homolog 5,5-dimethylbarbituric acid on N-nitrosodiethylamine-initiated renal and hepatic carcinogenesis in the F344/NCr rat.
Journal: Archives of toxicology 19920101
Title: Characterization of ethosuximide reduction of low-threshold calcium current in thalamic neurons.
Journal: Annals of neurology 19890601
Title: Specific petit mal anticonvulsants reduce calcium currents in thalamic neurons.
Journal: Neuroscience letters 19890313
Title: Cardiac defects in children of mothers receiving anticonvulsant therapy during pregnancy.
Journal: The Journal of pediatrics 19760801