Name: Name:Gbr 12935 dihydrochloride
Brand: AABLOCKS
SKU: AA00613E
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA00613E

Chemical Name: Gbr 12935 dihydrochloride

CAS Number: 67469-81-2

Molecular Formula: C28H36Cl2N2O

Molecular Weight: 487.5042

MDL Number: MFCD00083175

SMILES: c1ccc(cc1)CCCN1CCN(CC1)CCOC(c1ccccc1)c1ccccc1.Cl.Cl

Properties

Form: Solid

Storage: Inert atmosphere;-20 ℃;

Complexity: 440

Covalently-Bonded Unit Count: 3

Heavy Atom Count: 33

Hydrogen Bond Acceptor Count: 3

Hydrogen Bond Donor Count: 2

Rotatable Bond Count: 10

Literature fold

Title: Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.

Journal: Nature chemical biology20091001

Title: Hiroi T, et al. Specific binding of 1--(diphenylmethoxy)ethyl-4-(3-phenyl propyl) piperazine (GBR-12935), an inhibitor of the dopamine transporter, to human CYP2D6. Biochem Pharmacol. 1997 Jun 15;53(12):1937-9.

Title: Rahman S, et al. Negative interaction of dopamine D2 receptor antagonists and GBR 12909 and GBR 12935 dopamine uptake inhibitors in the nucleus accumbens. Eur J Pharmacol. 2001 Feb 23;414(1):37-44.

Title: Tolliver BK, et al. Comparison of cocaine and GBR 12935: effects on locomotor activity and stereotypy in two inbred mouse strains. Pharmacol Biochem Behav. 1994 Jul;48(3):733-9.

67469-81-2 | Gbr 12935 dihydrochloride