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992-78-9,MFCD11973816
Catalog No.:AA00662U

992-78-9 | 1,4-Benzenediol, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-

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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
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Technical Information
Catalog Number:
AA00662U
Chemical Name:
1,4-Benzenediol, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-
CAS Number:
992-78-9
Molecular Formula:
C59H92O4
Molecular Weight:
865.3594
MDL Number:
MFCD11973816
SMILES:
COc1c(O)c(C/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CC/C=C(/CCC=C(C)C)\C)\C)\C)\C)\C)\C)\C)\C)\C)c(c(c1OC)O)C
Properties
Properties
 
Form:
Solid  
MP:
46-48C  

Computed Properties
 
Complexity:
1600  
Covalently-Bonded Unit Count:
1  
Defined Bond Stereocenter Count:
9  
Heavy Atom Count:
63  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
31  
XLogP3:
20.2  

Literature

Title: Kinetic study of the α-tocopherol-regeneration reaction of ubiquinol-10 in methanol and acetonitrile solutions: notable effect of the alkali and alkaline earth metal salts on the reaction rates.

Journal: The journal of physical chemistry. B 20120301

Title: Measurement of oxidized and reduced coenzyme Q in biological fluids, cells, and tissues: an HPLC-EC method.

Journal: Methods in molecular biology (Clifton, N.J.) 20120101

Title: A study of cytochrome bo3 in a tethered bilayer lipid membrane.

Journal: Biochimica et biophysica acta 20101201

Title: 4-Nitrobenzoate inhibits coenzyme Q biosynthesis in mammalian cell cultures.

Journal: Nature chemical biology 20100701

Title: Coenzyme Q10 treatment ameliorates acute cisplatin nephrotoxicity in mice.

Journal: Toxicology 20100101

Title: Effects of ubiquinol-10 on microRNA-146a expression in vitro and in vivo.

Journal: Mediators of inflammation 20090101

Title: Fluorescence studies of the interactions of ubiquinol-10 with liposomes.

Journal: Photochemistry and photobiology 20080101

Title: Comparison between the free-radical-scavenging activities with vitamin E and ubiquinol in biological systems based on their reaction rates: a research account.

Journal: BioFactors (Oxford, England) 20080101

Title: Determination of the ubiquinol-10 and ubiquinone-10 (coenzyme Q10) in human serum by liquid chromatography tandem mass spectrometry to evaluate the oxidative stress.

Journal: Journal of chromatography. A 20071221

Title: Ubiquinol-10/lipids ratios in consecutive patients with different angiographic findings.

Journal: Clinica chimica acta; international journal of clinical chemistry 20070501

Title: Structure-activity relationship of the free-radical-scavenging reaction by vitamin E (alpha-, beta-, gamma-, delta-Tocopherols) and ubiquinol-10: pH dependence of the reaction rates.

Journal: The journal of physical chemistry. B 20070125

Title: Effects of fenofibrate therapy on plasma ubiquinol-10 and ubiquinone-10 levels in Japanese patients with hyperlipidemia and type 2 diabetes mellitus.

Journal: Pharmacotherapy 20060401

Title: Reduction of serum ubiquinol-10 and ubiquinone-10 levels by atorvastatin in hypercholesterolemic patients.

Journal: Journal of atherosclerosis and thrombosis 20050101

Title: The regular supplementation with an antioxidant mixture decreases oxidative stress in healthy humans. Gender effect.

Journal: Clinica chimica acta; international journal of clinical chemistry 20041101

Title: Role of beta2-glycoprotein I, LDL-, and antioxidant levels in hypercholesterolemic elderly subjects.

Journal: Antioxidants & redox signaling 20040401

Title: Short-term and long-term vitamin C supplementation in humans dose-dependently increases the resistance of plasma to ex vivo lipid peroxidation.

Journal: Archives of biochemistry and biophysics 20040301

Title: The mammalian cytosolic selenoenzyme thioredoxin reductase reduces ubiquinone. A novel mechanism for defense against oxidative stress.

Journal: The Journal of biological chemistry 20030124

Title: Role of active oxygen species and antioxidants in photoaging.

Journal: Journal of dermatological science 20010801

Title: Effects of diets enriched with two different plant stanol ester mixtures on plasma ubiquinol-10 and fat-soluble antioxidant concentrations.

Journal: Metabolism: clinical and experimental 20010501

Title: Plasma vitamin C levels are decreased and correlated with brain damage in patients with intracranial hemorrhage or head trauma.

Journal: Stroke 20010401

Title: Ubiquinol: an endogenous antioxidant in aerobic organisms.

Journal: The Clinical investigator 19930101

Title: Dietary supplementation with coenzyme Q10 results in increased levels of ubiquinol-10 within circulating lipoproteins and increased resistance of human low-density lipoprotein to the initiation of lipid peroxidation.

Journal: Biochimica et biophysica acta 19920626

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Tags:992-78-9 Molecular Formula|992-78-9 MDL|992-78-9 SMILES|992-78-9 1,4-Benzenediol, 2-[(2E,6E,10E,14E,18E,22E,26E,30E,34E)-3,7,11,15,19,23,27,31,35,39-decamethyl-2,6,10,14,18,22,26,30,34,38-tetracontadecaen-1-yl]-5,6-dimethoxy-3-methyl-