Catalog No.:AA006C0H

70146-78-0 | Diethyl 2-(4-bromobenzyl)malonate

Name: Name:Diethyl 2-(4-bromobenzyl)malonate
Brand: AABLOCKS
SKU: AA006C0H
Availability: InStock
Rating: 90 (10 reviews)

Pack Size

Purity

Availability

Price(USD)

Quantity

250mg

97%

in stock

$79.00 $55.00

- +

97%

in stock

$170.00 $119.00

- +

97%

in stock

$552.00 $387.00

- +

25g

97%

in stock

$2,140.00 $1,498.00

- +

Technical Information
Properties
Upstream Synthesis Route
Downstream Synthesis Route
Literature
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Technical Information
Properties
Upstream Synthesis Route
Downstream Synthesis Route
Literature

Technical Information

Catalog Number:

AA006C0H

Chemical Name:

Diethyl 2-(4-bromobenzyl)malonate

CAS Number:

70146-78-0

Molecular Formula:

C14H17BrO4

Molecular Weight:

329.1864

MDL Number:

MFCD00017852

SMILES:

CCOC(=O)C(C(=O)OCC)Cc1ccc(cc1)Br

Properties

BP:

193-198°C at 14 mmHg

Form:

Liquid

Storage:

Keep in dry area;Room Temperature;

Computed Properties

Complexity:

280

Covalently-Bonded Unit Count:

Heavy Atom Count:

Hydrogen Bond Acceptor Count:

Rotatable Bond Count:

XLogP3:

3.5

Upstream Synthesis Route

589-15-1

105-53-3

70146-78-0

[1]Patent:WO2010/105179,2010,A2,.Locationinpatent:Page/Pagecolumn76

[2]JournalofOrganicChemistry,1984,vol.49,#22,p.4226-4237

[3]ChemistryofHeterocyclicCompounds(NewYork,NY,UnitedStates),1994,vol.30,#8,p.905-915

[4]KhimiyaGeterotsiklicheskikhSoedinenii,1993,#8,p.1052-1062

[5]TetrahedronAsymmetry,2001,vol.12,#4,p.585-596

[6]Patent:WO2017/96130,2017,A1,.Locationinpatent:Page/Pagecolumn116;119

[7]Patent:US6342622,2002,B1,.Locationinpatent:ExampleII

[8]Patent:US2013/324464,2013,A1,.Locationinpatent:Paragraph0164

[9]Patent:EP2676965,2013,A1,.Locationinpatent:Paragraph0046;0109

[10]JournalofMedicinalChemistry,2014,vol.57,#9,p.3874-3883

589-15-1

105-53-3

70146-78-0

[1]JournalofMedicinalChemistry,2003,vol.46,#3,p.399-408

[2]ChemischeBerichte,1933,vol.66,p.1464,1467

[3]ChemischeBerichte,1933,vol.66,p.1464,1467

589-17-3

105-53-3

70146-78-0

[1]JournalofMedicinalChemistry,2012,vol.55,#7,p.3285-3306

[2]Journalofmedicinalchemistry,1970,vol.13,#5,p.820-826

[3]Molecules,2018,vol.23,#5,

107558-73-6

70146-78-0

[1]Patent:US2003/166697,2003,A1,

589-15-1

70146-78-0

[1]Polymer,2016,vol.97,p.550-558

Downstream Synthesis Route

589-15-1

105-53-3

70146-78-0

[1]CurrentPatentAssignee:ABBVIEINC-WO2010/105179,2010,A2Locationinpatent:Page/Pagecolumn76

[2]Adamczyk,Maciej;Watt,DavidS.;Netzel,DanielA.[JournalofOrganicChemistry,1984,vol.49,#22,p.4226-4237]

[3]Gribkov,A.A.;Borovkov,V.V.;Evstigneeva,R.P.;Sakata,Y.[ChemistryofHeterocyclicCompounds,1994,vol.30,#8,p.905-915][KhimiyaGeterotsiklicheskikhSoedinenii,1993,#8,p.1052-1062]

[4]Godha,AtulK.;Thiruvengadam,Jayaraman;Abhilash,Viswanadhan;Balgi,Prajwal;Narayanareddy;Vignesh,Kumaresan;Gadakh,AmolV.;Sathiyanarayanan;Ganesh,Sambasivam[NewJournalofChemistry,2019,vol.43,#40,p.16041-16045]

[5]Ao,Yu-Fei;Zhang,Li-Bin;Wang,Qi-Qiang;Wang,De-Xian;Wang,Mei-Xiang[AdvancedSynthesisandCatalysis,2018,vol.360,#23,p.4594-4603]

[6]Kawasaki,Masashi;Goto,Michimasa;Kawabata,Shigeki;Kometani,Tadashi[TetrahedronAsymmetry,2001,vol.12,#4,p.585-596]

[7]CurrentPatentAssignee:BRISTOL-MYERSSQUIBBCO-WO2017/96130,2017,A1Locationinpatent:Page/Pagecolumn116;119

[8]CurrentPatentAssignee:ARAMCO(in:SaudiArabiaGovernment);SABIC(in:SaudiArabiaGovernment);GOVERNMENTOFSAUDIARABIA-US6342622,2002,B1Locationinpatent:ExampleII

[9]CurrentPatentAssignee:SHANGPHARMAVENTUREDEVELOPMENTJIANGSU-US2013/324464,2013,A1Locationinpatent:Paragraph0164

[10]CurrentPatentAssignee:SHANGPHARMAVENTUREDEVELOPMENTJIANGSU-EP2676965,2013,A1Locationinpatent:Paragraph0046;0109

[11]Jayasekara,P.Suresh;Barrett,MatthewO.;Ball,ChristopherB.;Brown,KyleA.;Hammes,Eva;Balasubramanian,Ramachandran;Harden,T.Kendall;Jacobson,KennethA.[JournalofMedicinalChemistry,2014,vol.57,#9,p.3874-3883]

[12]Guo,Jia;Xu,Cong;Liu,Xiaowei;Wang,Mang[OrganicandBiomolecularChemistry,2019,vol.17,#8,p.2162-2168]

70146-78-0

55394-81-5

[1]JournalofMedicinalChemistry,2003,vol.46,p.399-408

[2]JournalofOrganicChemistry,1984,vol.49,p.4226-4237

70146-78-0

874-35-1

[1]Adamczyk,Maciej;Watt,DavidS.;Netzel,DanielA.[JournalofOrganicChemistry,1984,vol.49,#22,p.4226-4237]

70146-78-0

75476-86-7

[1]JournalofOrganicChemistry,1984,vol.49,p.4226-4237

70146-78-0