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90-18-6,MFCD00017428
Catalog No.:AA006IZ4

90-18-6 | Quercetagetin

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1mg
≥98%
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$188.00   $131.00
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5mg
≥98%
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$463.00   $324.00
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10mg
98%
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$747.00   $523.00
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25mg
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA006IZ4
Chemical Name:
Quercetagetin
CAS Number:
90-18-6
Molecular Formula:
C15H10O8
Molecular Weight:
318.2351
MDL Number:
MFCD00017428
SMILES:
Oc1ccc(cc1O)c1oc2cc(O)c(c(c2c(=O)c1O)O)O
NSC Number:
115916
Properties
Computed Properties
 
Complexity:
518  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
23  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
6  
Rotatable Bond Count:
1  
XLogP3:
1.2  

Literature

Title: Combination of Quercetin and 2-Methoxyestradiol Enhances Inhibition of Human Prostate Cancer LNCaP and PC-3 Cells Xenograft Tumor Growth.

Journal: PloS one 20150101

Title: eNOS-JNK1-AR signaling pathway mediates deltamethrin-induced germ cells apoptosis in testes of adult rats.

Journal: Environmental toxicology and pharmacology 20141101

Title: The hepatitis B virus ribonuclease H is sensitive to inhibitors of the human immunodeficiency virus ribonuclease H and integrase enzymes.

Journal: PLoS pathogens 20130101

Title: Inhibition of Pim-1 attenuates the proliferation and migration in nasopharyngeal carcinoma cells.

Journal: Asian Pacific journal of tropical medicine 20120801

Title: Isolation of a new phlorotannin, a potent inhibitor of carbohydrate-hydrolyzing enzymes, from the brown alga Sargassum patens.

Journal: Journal of agricultural and food chemistry 20120606

Title: HPLC-ESIMS(n) profiling, isolation, structural elucidation, and evaluation of the antioxidant potential of phenolics from Paepalanthus geniculatus.

Journal: Journal of natural products 20120427

Title: Investigation into the antioxidant activity and chemical composition of alcoholic extracts from defatted marigold (Tagetes erecta L.) residue.

Journal: Fitoterapia 20120401

Title: Secondary Metabolites from Plants Inhibiting ABC Transporters and Reversing Resistance of Cancer Cells and Microbes to Cytotoxic and Antimicrobial Agents.

Journal: Frontiers in microbiology 20120101

Title: Synthesis and biological activity of novel tiliroside derivants.

Journal: European journal of medicinal chemistry 20111001

Title: Isolation and identification of an antioxidant flavonoid compound from citrus-processing by-product.

Journal: Journal of the science of food and agriculture 20110815

Title: Flavonoids as inhibitors of human CD38.

Journal: Bioorganic & medicinal chemistry letters 20110701

Title: Activation of a non-genomic Pim-1/Bad-Pser75 module is required for an efficient pro-survival effect of Bcl-xL induced by androgen in LNCaP cells.

Journal: The international journal of biochemistry & cell biology 20110401

Title: The membrane transport of flavonoids from Crossostephium chinense across the Caco-2 monolayer.

Journal: Biopharmaceutics & drug disposition 20110101

Title: Eriocaulon buergerianum extract protects PC12 cells and neurons in zebrafish against 6-hydroxydopamine-induced damage.

Journal: Chinese medicine 20110101

Title: Feverfew (Tanacetum parthenium L.): A systematic review.

Journal: Pharmacognosy reviews 20110101

Title: Identification by high-throughput screening of inhibitors of Schistosoma mansoni NAD(+) catabolizing enzyme.

Journal: Bioorganic & medicinal chemistry 20101115

Title: The flavonoids luteolin and quercetagetin inhibit lipoteichoic acid actions on H9c2 cardiomyocytes.

Journal: International immunopharmacology 20100901

Title: Identification and structure-activity relationship of 8-hydroxy-quinoline-7-carboxylic acid derivatives as inhibitors of Pim-1 kinase.

Journal: Bioorganic & medicinal chemistry letters 20100501

Title: Transcriptional regulation of Pim-1 kinase in vascular smooth muscle cells and its role for proliferation.

Journal: Basic research in cardiology 20100301

Title: Antioxidant effects of Glechoma hederacea as a food additive.

Journal: Natural product communications 20100101

Title: Binding of protein kinase inhibitors to synapsin I inferred from pair-wise binding site similarity measurements.

Journal: PloS one 20100101

Title: Secondary metabolites as DNA topoisomerase inhibitors: A new era towards designing of anticancer drugs.

Journal: Pharmacognosy reviews 20100101

Title: [Bioactivity guided isolation of alpha-glucosidase inhibitor from whole herbs of Crossostephium chinense].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20090901

Title: Hit to lead account of the discovery of a new class of inhibitors of Pim kinases and crystallographic studies revealing an unusual kinase binding mode.

Journal: Journal of medicinal chemistry 20090409

Title: Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.

Journal: Journal of medicinal chemistry 20090108

Title: Structure-activity relationships of flavonoids as potential inhibitors of glycogen phosphorylase.

Journal: Journal of agricultural and food chemistry 20080625

Title: Biochemical and structural analysis of substrate promiscuity in plant Mg2+-dependent O-methyltransferases.

Journal: Journal of molecular biology 20080418

Title: [Effects of quercetin on human laryngeal cancer Hep-2 cells].

Journal: Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 20080201

Title: The impact of the human DNA topoisomerase II C-terminal domain on activity.

Journal: PloS one 20080101

Title: Effects of various methoxyflavones on vincristine uptake and multidrug resistance to vincristine in P-gp-overexpressing K562/ADM cells.

Journal: Pharmaceutical research 20071001

Title: Comparative molecular field analysis of flavonoid inhibitors of the PIM-1 kinase.

Journal: Bioorganic & medicinal chemistry 20071001

Title: The effect of flavonoids on transduction mechanisms in lipopolysaccharide-treated human gingival fibroblasts.

Journal: International immunopharmacology 20070901

Title: Structure-activity relationship of flavonoids for inhibition of epidermal growth factor-induced transformation of JB6 Cl 41 cells.

Journal: Molecular carcinogenesis 20070601

Title: Characterization of a potent and selective small-molecule inhibitor of the PIM1 kinase.

Journal: Molecular cancer therapeutics 20070101

Title: Antifungal and antibacterial activities of Mexican tarragon (Tagetes lucida).

Journal: Journal of agricultural and food chemistry 20060517

Title: Pro-oxidative effect of beta-carotene and the interaction with flavonoids on UVA-induced DNA strand breaks in mouse fibroblast C3H10T1/2 cells.

Journal: The Journal of nutritional biochemistry 20051201

Title: Molecular targets of dietary polyphenols with anti-inflammatory properties.

Journal: Yonsei medical journal 20051031

Title: Acylated quercetagetin glycosides with antioxidant activity from Tagetes maxima.

Journal: Phytochemistry 20051001

Title: Vasorelaxing effects of flavonoids: investigation on the possible involvement of potassium channels.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20041001

Title: Kinetic study of flavonoid reactions with stable radicals.

Journal: Journal of agricultural and food chemistry 20040519

Title: G2-M arrest and antimitotic activity mediated by casticin, a flavonoid isolated from Viticis Fructus (Vitex rotundifolia Linne fil.).

Journal: Cancer letters 20040510

Title: Effects of natural flavones and flavonols on the kinase activity of Cdk5.

Journal: Journal of natural products 20040301

Title: Free radical scavengers and antioxidants from Tagetes mendocina.

Journal: Zeitschrift fur Naturforschung. C, Journal of biosciences 20040101

Title: Variations in lipophilic and vacuolar flavonoids among European Pulicaria species.

Journal: Phytochemistry 20030901

Title: Sesquiterpene lactones from Anthemis altissima and their anti-Helicobacter pylori activity.

Journal: Journal of natural products 20030501

Title: Identification of lipophilic flavones and flavonols by comparative HPLC, TLC and UV spectral analysis.

Journal: Phytochemical analysis : PCA 20030101

Title: Developing a dynamic pharmacophore model for HIV-1 integrase.

Journal: Journal of medicinal chemistry 20000601

Title: Human immunodeficiency virus type 1 cDNA integration: new aromatic hydroxylated inhibitors and studies of the inhibition mechanism.

Journal: Antimicrobial agents and chemotherapy 19980901

Title: Discovery and analysis of inhibitors of the human immunodeficiency integrase.

Journal: Drug design and discovery 19970501

Title: HIV-1 integrase pharmacophore: discovery of inhibitors through three-dimensional database searching.

Journal: Journal of medicinal chemistry 19970314

Title: Equivalent inhibition of half-site and full-site retroviral strand transfer reactions by structurally diverse compounds.

Journal: Journal of virology 19970101

Title: Differential inhibition of HIV-1 preintegration complexes and purified integrase protein by small molecules.

Journal: Proceedings of the National Academy of Sciences of the United States of America 19960903

Title: Inhibition of HIV-1 integrase by flavones, caffeic acid phenethyl ester (CAPE) and related compounds.

Journal: Biochemical pharmacology 19940803

Title: Effects of flavonoids on Naja naja and human recombinant synovial phospholipases A2 and inflammatory responses in mice.

Journal: Life sciences 19940101

Title: Flavones are inhibitors of HIV-1 proteinase.

Journal: Biochemical and biophysical research communications 19921030

Title: Differential inhibitory effects of various flavonoids on the activities of reverse transcriptase and cellular DNA and RNA polymerases.

Journal: European journal of biochemistry 19900705

Title: Induction of Mx-related protein in cat peripheral blood mononuclear cells after administration of recombinant human interferon hybrid.

Journal: Antiviral research 19900201

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Tags:90-18-6 Molecular Formula|90-18-6 MDL|90-18-6 SMILES|90-18-6 Quercetagetin