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668-49-5
Catalog No.:AA006Q8G

668-49-5 | 4-(3,6-DIHYDROXY-10,13-DIMETHYL-2,3,4,5,6,7,8,9,11,12,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL)PENTANOIC ACID

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1mg
≥95%
in stock  
$133.00   $93.00
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5mg
≥95%
in stock  
$589.00   $412.00
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10mg
≥95%
in stock  
$1,040.00   $728.00
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  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA006Q8G
Chemical Name:
4-(3,6-DIHYDROXY-10,13-DIMETHYL-2,3,4,5,6,7,8,9,11,12,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL)PENTANOIC ACID
CAS Number:
668-49-5
Molecular Formula:
C24H40O4
Molecular Weight:
392.5720
SMILES:
OC1CCC2(C(C1)C(O)CC1C2CCC2(C1CCC2C(CCC(=O)O)C)C)C
Properties
Properties
 
Form:
Solid  
MP:
204 - 208°C  
Storage:
-20 ℃;Inert atmosphere;  

Computed Properties
 
Complexity:
605  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
4  
Undefined Atom Stereocenter Count:
10  
XLogP3:
4.9  

Literature

Title: BASIC--a bile acid-sensitive ion channel highly expressed in bile ducts.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20121001

Title: A tandem mass spectrometric study of bile acids: interpretation of fragmentation pathways and differentiation of steroid isomers.

Journal: Steroids 20120201

Title: Improved analysis of bile acids in tissues and intestinal contents of rats using LC/ESI-MS.

Journal: Journal of lipid research 20090101

Title: The inhibitory effects of cholalic acid and hyodeoxycholalic acid on the expression of TNFalpha and IL-1beta after cerebral ischemia in rats.

Journal: Archives of pharmacal research 20090101

Title: Novel polymorphic human UDP-glucuronosyltransferase 2A3: cloning, functional characterization of enzyme variants, comparative tissue expression, and gene induction.

Journal: Molecular pharmacology 20080901

Title: [Determination of chyodeoxycholic acid in Bile Arisaema by HPLC-ELSD].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20070801

Title: Simultaneous determination of geniposide, baicalin, cholic acid and hyodeoxycholic acid in rat serum for the pharmacokinetic investigations by high performance liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20060914

Title: Mice lacking Mrp3 (Abcc3) have normal bile salt transport, but altered hepatic transport of endogenous glucuronides.

Journal: Journal of hepatology 20060401

Title: Enzymatic production of bile Acid glucuronides used as analytical standards for liquid chromatography-mass spectrometry analyses.

Journal: Molecular pharmaceutics 20060101

Title: Resistance to ursodeoxycholic acid-induced growth arrest can also result in resistance to deoxycholic acid-induced apoptosis and increased tumorgenicity.

Journal: BMC cancer 20060101

Title: [Study on extraction technique of HDCA].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20040501

Title: Steroids in the intestinal tract of rats are affected by dietary-fibre-rich barley-based diets.

Journal: The British journal of nutrition 20031101

Title: Glucosidation of hyodeoxycholic acid by UDP-glucuronosyltransferase 2B7.

Journal: Biochemical pharmacology 20030201

Title: [Study on effect of qingkailing injection and its active principle in inducing cell apoptosis in human acute promyelocytic leukemia].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20011101

Title: Hyodeoxycholic acid efficiently suppresses atherosclerosis formation and plasma cholesterol levels in mice.

Journal: Journal of lipid research 20010801

Title: Hydrophilic and hydrophobic bile acids exhibit different cytotoxicities through cytolysis, interleukin-8 synthesis and apoptosis in the intestinal epithelial cell lines. IEC-6 and Caco-2 cells.

Journal: Scandinavian journal of gastroenterology 20010501

Title: Isolation and characterization of hyodeoxycholic-acid: UDP-glucuronosyltransferase from human liver.

Journal: European journal of biochemistry 19910901

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SDS
Tags:668-49-5 Molecular Formula|668-49-5 MDL|668-49-5 SMILES|668-49-5 4-(3,6-DIHYDROXY-10,13-DIMETHYL-2,3,4,5,6,7,8,9,11,12,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL)PENTANOIC ACID