Title: Protease inhibitor monotherapy: what is its role?
Journal: Current HIV/AIDS reports 20120601
Title: Long-term efficacy and safety of once-daily fosamprenavir 1400 mg boosted by ritonavir 100 mg: the BOLD100 study.
Journal: International journal of STD & AIDS 20120301
Title: Interactions between buprenorphine and the protease inhibitors darunavir-ritonavir and fosamprenavir-ritonavir.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20120201
Title: Hepatic safety profile of fosamprenavir-containing regimens in HIV-1-infected patients with or without hepatitis B or C coinfection.
Journal: HIV clinical trials 20120101
Title: Efficacy and safety of a dual boosted protease inhibitor-based regimen, atazanavir and fosamprenavir/ritonavir, against HIV: experience in a pediatric population.
Journal: BMC infectious diseases 20120101
Title: Viral response in stable patients switching to fosamprenavir/ritonavir monotherapy (the FONT Study).
Journal: HIV medicine 20110801
Title: Liver toxicity of antiretroviral combinations including fosamprenavir plus ritonavir 1400/100 mg once daily in HIV/hepatitis C virus-coinfected patients.
Journal: AIDS patient care and STDs 20110701
Title: The inclusion of historical control data may reduce the power of a confirmatory study.
Journal: Statistics in medicine 20110530
Title: Development and validation of discriminating method of dissolution for fosamprenavir tablets based on in vivo data.
Journal: Journal of pharmaceutical and biomedical analysis 20110220
Title: Food-dependent disintegration of immediate release fosamprenavir tablets: in vitro evaluation using magnetic resonance imaging and a dynamic gastrointestinal system.
Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20110201
Title: Changes in lipid profiles after switching to a protease inhibitor-containing cART--unfavourable effect of fosamprenavir in obese patients.
Journal: European journal of medical research 20110101
Title: Safety of fosamprenavir in a cohort of HIV-1-infected patients with co-morbidities.
Journal: In vivo (Athens, Greece) 20110101
Title: Avascular necrosis of the talus in a HIV-infected patient.
Journal: Foot & ankle international 20101201
Title: Effect of posaconazole on the pharmacokinetics of fosamprenavir and vice versa in healthy volunteers.
Journal: The Journal of antimicrobial chemotherapy 20101001
Title: Safety and efficacy of fosamprenavir in human immunodeficiency virus-infected pregnant women.
Journal: The Pediatric infectious disease journal 20101001
Title: Impact of individual antiretroviral drugs on the risk of myocardial infarction in human immunodeficiency virus-infected patients: a case-control study nested within the French Hospital Database on HIV ANRS cohort CO4.
Journal: Archives of internal medicine 20100726
Title: Fosamprenavir treatment in a highly active antiretroviral therapy schedule induces a HCV-RNA decrease and a Th1 network boost in HIV/HCV-coinfected patients.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20100601
Title: Long-term efficacy and safety of fosamprenavir in human immunodeficiency virus-infected pediatric patients.
Journal: The Pediatric infectious disease journal 20100601
Title: Electrochemical evaluation and determination of antiretroviral drug fosamprenavir using boron-doped diamond and glassy carbon electrodes.
Journal: Analytical and bioanalytical chemistry 20100501
Title: Impact of low abundance HIV variants on response to ritonavir-boosted atazanavir or fosamprenavir given once daily with tenofovir/emtricitabine in antiretroviral-naive HIV-infected patients.
Journal: AIDS research and human retroviruses 20100401
Title: Simultaneous bioanalysis of a phosphate prodrug and its parent compound using a multiplexed LC-MS method.
Journal: Bioanalysis 20100401
Title: Steady-state amprenavir and tenofovir pharmacokinetics after coadministration of unboosted or ritonavir-boosted fosamprenavir with tenofovir disoproxil fumarate in healthy volunteers.
Journal: HIV medicine 20100301
Title: Heart attack warning issued.
Journal: AIDS patient care and STDs 20100101
Title: Effects of intermittent IL-2 alone or with peri-cycle antiretroviral therapy in early HIV infection: the STALWART study.
Journal: PloS one 20100101
Title: [Adverse reactions of atazanavir, fosamprenavir and tipranavir in 'real life'].
Journal: Therapie 20100101
Title: Similar virologic and immunologic efficacy with fosamprenavir boosted with 100 mg or 200 mg of ritonavir in HIV-infected patients: results of the LESS trial.
Journal: HIV clinical trials 20100101
Title: Effect of boosted fosamprenavir or lopinavir-based combinations on whole-body insulin sensitivity and lipids in treatment-naive HIV-type-1-positive men.
Journal: Antiviral therapy 20100101
Title: Fosamprenavir/ritonavir in advanced HIV disease (TRIAD): a randomized study of high-dose, dual-boosted or standard dose fosamprenavir/ritonavir in HIV-1-infected patients with antiretroviral resistance.
Journal: The Journal of antimicrobial chemotherapy 20090801
Title: Pharmacokinetics of concurrent administration of fosamprenavir and atazanavir without ritonavir in human immunodeficiency virus-negative subjects.
Journal: Pharmacotherapy 20090801
Title: Comment on: Unboosted fosamprenavir is associated with low drug exposure in HIV-infected patients with mild-moderate liver impairment resulting from HCV-related cirrhosis.
Journal: The Journal of antimicrobial chemotherapy 20090701
Title: Efficacy and safety of ritonavir-boosted dual protease inhibitor therapy in antiretroviral-naive HIV-1-infected patients: the 2IP ANRS 127 study.
Journal: The Journal of antimicrobial chemotherapy 20090701
Title: Favourable use of non-boosted fosamprenavir in patients treated with warfarin.
Journal: International journal of STD & AIDS 20090601
Title: Comparison of once-daily fosamprenavir boosted with either 100 or 200 mg of ritonavir, in combination with abacavir/lamivudine: 96-week results from COL100758.
Journal: AIDS research and human retroviruses 20090401
Title: Unboosted fosamprenavir is associated with low drug exposure in HIV-infected patients with mild-moderate liver impairment resulting from HCV-related cirrhosis.
Journal: The Journal of antimicrobial chemotherapy 20090301
Title: Highly active antiretroviral therapy-associated ptosis in patients with human immunodeficiency virus.
Journal: Archives of ophthalmology (Chicago, Ill. : 1960) 20090301
Title: Fosamprenavir (GW433908)/ritonavir in HIV-infected patients: efficacy and safety results from the Spanish Expanded Access Program.
Journal: Enfermedades infecciosas y microbiologia clinica 20090101
Title: Virologic response and safety of the abacavir/lamivudine fixed-dose formulation as part of highly active antiretroviral therapy: analyses of six clinical studies.
Journal: HIV clinical trials 20090101
Title: Long-term efficacy and safety of fosamprenavir plus ritonavir versus lopinavir/ritonavir in combination with abacavir/lamivudine over 144 weeks.
Journal: HIV clinical trials 20090101
Title: Occurrence of selective ritonavir nonadherence and dose-staggering in recipients of boosted HIV-1 protease inhibitor therapy.
Journal: HIV clinical trials 20090101
Title: Steady-state amprenavir, tenofovir, and emtricitabine pharmacokinetics before and after reducing ritonavir boosting of a fosamprenavir/tenofovir/emtricitabine regimen from 200 mg to 100 mg once daily (TELEX II).
Journal: HIV clinical trials 20090101
Title: Study of once-daily versus twice-daily fosamprenavir plus ritonavir administered with abacavir/lamivudine once daily in antiretroviral-naïve HIV-1-infected adult subjects.
Journal: HIV clinical trials 20090101
Title: Optimal fosamprenavir regimen to prevent lipid abnormalities.
Journal: Acta bio-medica : Atenei Parmensis 20090101
Title: Four posters add to our knowledge of Lexiva.
Journal: Project Inform perspective 20081201
Title: Tolerability of fosamprenavir/ritonavir associated with zidovudine-lamivudine used as postexposure prophylaxis for HIV infection.
Journal: Journal of acquired immune deficiency syndromes (1999) 20081101
Title: Doxorubicin-induced hyperpigmentation.
Journal: Dermatology online journal 20081015
Title: Efficacy and tolerability of a fosamprenavir-ritonavir-based versus a lopinavir-ritonavir-based antiretroviral treatment in 82 therapy-naïve patients with HIV-1 infection.
Journal: International journal of STD & AIDS 20080801
Title: Pharmacokinetics and pharmacodynamics of methadone enantiomers after coadministration with fosamprenavir-ritonavir in opioid-dependent subjects.
Journal: Pharmacotherapy 20080701
Title: Quality control of protease inhibitors.
Journal: Journal of pharmaceutical sciences 20080601
Title: Clinically validated mutation scores for HIV-1 resistance to fosamprenavir/ritonavir.
Journal: The Journal of antimicrobial chemotherapy 20080601
Title: Effects of atazanavir/ritonavir or fosamprenavir/ritonavir on the pharmacokinetics of rosuvastatin.
Journal: Journal of cardiovascular pharmacology 20080601
Title: [Individualized therapy with fosamprenavir/r. A PI suitable in liver problems].
Journal: MMW Fortschritte der Medizin 20080428
Title: [Plasma levels following the switch from amprenavir to fosamprenavir in HIV-infected patients under antiretroviral treatment with lopinavir/ritonavir].
Journal: Enfermedades infecciosas y microbiologia clinica 20080301
Title: Impact of nevirapine or efavirenz co-administration on ritonavir-boosted amprenavir pharmacokinetics in HIV-infected patients.
Journal: Fundamental & clinical pharmacology 20080201
Title: FDA notifications. Fosamprenavir label is updated.
Journal: AIDS alert 20080201
Title: Pharmacokinetics of an indinavir-ritonavir-fosamprenavir regimen in patients with human immunodeficiency virus.
Journal: Pharmacotherapy 20080101
Title: Randomized study of dual versus single ritonavir-enhanced protease inhibitors for protease inhibitor-experienced patients with HIV.
Journal: HIV clinical trials 20080101
Title: Drop in trough blood concentrations of tacrolimus after switching from nelfinavir to fosamprenavir in four HIV-infected liver transplant patients.
Journal: Antiviral therapy 20080101
Title: Low rate of adverse hepatic events associated with fosamprenavir/ritonavir-based antiretroviral regimens.
Journal: HIV clinical trials 20080101
Title: Lower dose of ritonavir approved for use with fosamprenavir.
Journal: AIDS clinical care 20071201
Title: FDA notifications. FDA approves NDA for Lexiva.
Journal: AIDS alert 20071201
Title: Parallel monitoring of plasma and intraluminal drug concentrations in man after oral administration of fosamprenavir in the fasted and fed state.
Journal: Pharmaceutical research 20071001
Title: Amprenavir and ritonavir plasma concentrations in HIV-infected patients treated with fosamprenavir/ritonavir with various degrees of liver impairment.
Journal: The Journal of antimicrobial chemotherapy 20071001
Title: Steady-state pharmacokinetics of once-daily fosamprenavir/ritonavir and atazanavir/ritonavir alone and in combination with 20 mg omeprazole in healthy volunteers.
Journal: HIV medicine 20071001
Title: Development and evaluation of an immunoassay for the monitoring of the anti-HIV drug amprenavir.
Journal: Journal of immunological methods 20070831
Title: FDA notifications. FDA approves new formulation of Lexiva.
Journal: AIDS alert 20070801
Title: Fosamprenavir/ritonavir plus tenofovir does not affect amprenavir pharmacokinetics: no effect of tenofovir.
Journal: AIDS (London, England) 20070619
Title: Pharmacokinetics of once-daily tenofovir, emtricitabine, ritonavir and fosamprenavir in HIV-infected subjects.
Journal: AIDS (London, England) 20070619
Title: Fosamprenavir calcium plus ritonavir for HIV infection.
Journal: Expert review of anti-infective therapy 20070601
Title: In vitro behavior of a phosphate ester prodrug of amprenavir in human intestinal fluids and in the Caco-2 system: illustration of intraluminal supersaturation.
Journal: International journal of pharmaceutics 20070524
Title: Use of fosamprenavir, a sulfa-containing protease inhibitor, in HIV-infected patients with glucose-6-phosphate dehydrogenase deficiency.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20070315
Title: [Two year use of Telzir: what are the perspectives?].
Journal: Medecine et maladies infectieuses 20070301
Title: Genotypic resistance to lopinavir and fosamprenavir with or without ritonavir of clinical isolates from patients failing protease inhibitors-containing HAART regimens: prevalence and predictors.
Journal: Scandinavian journal of infectious diseases 20070101
Title: Amprenavir and lopinavir pharmacokinetics following coadministration of amprenavir or fosamprenavir with lopinavir/ritonavir, with or without efavirenz.
Journal: Antiviral therapy 20070101
Title: Evaluation of sex differences of fosamprenavir (with and without ritonavir) in HIV-infected men and women.
Journal: HIV clinical trials 20070101
Title: Meeting report. Report from ICAAC.
Journal: AIDS clinical care 20061201
Title: Clinically relevant pharmacology of neuropsychiatric drugs approved over the last three years: Part II.
Journal: Journal of psychiatric practice 20060901
Title: The KLEAN study of fosamprenavir-ritonavir versus lopinavir-ritonavir, each in combination with abacavir-lamivudine, for initial treatment of HIV infection over 48 weeks: a randomised non-inferiority trial.
Journal: Lancet (London, England) 20060805
Title: An update and review of antiretroviral therapy.
Journal: Pharmacotherapy 20060801
Title: Coadministration of esomeprazole with fosamprenavir has no impact on steady-state plasma amprenavir pharmacokinetics.
Journal: Journal of acquired immune deficiency syndromes (1999) 20060501
Title: Pharmacokinetic interaction between Amprenavir/Ritonavir and FosAmprenavir on cyclosporine in two patients with human immunodeficiency virus infection undergoing orthotopic liver transplantation.
Journal: Transplantation proceedings 20060501
Title: Long-term (120-Week) antiviral efficacy and tolerability of fosamprenavir/ritonavir once daily in therapy-naive patients with HIV-1 infection: an uncontrolled, open-label, single-arm follow-on study.
Journal: Clinical therapeutics 20060501
Title: Effects of esomeprazole on the pharmacokinetics of atazanavir and fosamprenavir in a patient with human immunodeficiency virus infection.
Journal: Pharmacotherapy 20060401
Title: Evolution of resistance during first-line treatment with boosted fosamprenavir is associated with baseline mutations.
Journal: AIDS (London, England) 20060102
Title: Interaction between atazanavir and fosamprenavir in the treatment of HIV-infected patients.
Journal: Journal of acquired immune deficiency syndromes (1999) 20060101
Title: Fosamprenavir : clinical pharmacokinetics and drug interactions of the amprenavir prodrug.
Journal: Clinical pharmacokinetics 20060101
Title: Fosamprenavir: drug development for adherence.
Journal: The Annals of pharmacotherapy 20060101
Title: Fosamprenavir clinical study meta-analysis in ART-naïve subjects: rare occurrence of virologic failure and selection of protease-associated mutations.
Journal: HIV clinical trials 20060101
Title: [The treatment of HIV infection].
Journal: Presse medicale (Paris, France : 1983) 20051119
Title: [Multicentre clinical trials: degree of homogeneity in the ethical-scientific review performed by research ethics committees].
Journal: Medicina clinica 20050917
Title: Lexiva: blood levels not lowered when taken simultaneously with Nexium.
Journal: AIDS treatment news 20050527
Title: [Long-term virus suppression. Expanding therapy options with protease inhibitor].
Journal: MMW Fortschritte der Medizin 20050425
Title: Combining fosamprenavir with lopinavir/ritonavir substantially reduces amprenavir and lopinavir exposure: ACTG protocol A5143 results.
Journal: AIDS (London, England) 20050128
Title: Amprenavir or fosamprenavir plus ritonavir in HIV infection: pharmacology, efficacy and tolerability profile.
Journal: Drugs 20050101
Title: Salvage therapy with ritonavir-boosted amprenavir/fosamprenavir: virological and immunological response in two years follow-up.
Journal: HIV clinical trials 20050101
Title: Steady-State pharmacokinetics of saquinavir hard-gel/ritonavir/fosamprenavir in HIV-1-infected patients.
Journal: Journal of acquired immune deficiency syndromes (1999) 20041101
Title: Pharmacokinetics of Telzir (fosamprenavir).
Journal: Journal of HIV therapy 20041101
Title: Fosamprenavir: advancing HIV protease inhibitor treatment options.
Journal: Expert opinion on pharmacotherapy 20040901
Title: SOLO: 48-week efficacy and safety comparison of once-daily fosamprenavir /ritonavir versus twice-daily nelfinavir in naive HIV-1-infected patients.
Journal: AIDS (London, England) 20040723
Title: New approaches to the industrial synthesis of HIV protease inhibitors.
Journal: Organic & biomolecular chemistry 20040721
Title: [Maintaining independence. New protease inhibitor receives drug approval recommendation].
Journal: MMW Fortschritte der Medizin 20040426
Title: [FPV plus SQV plus a mini-dose ritonavir. 'Double boosting with compatible partners].
Journal: MMW Fortschritte der Medizin 20040426
Title: Pharmacokinetics and safety of GW433908 and ritonavir, with and without efavirenz, in healthy volunteers.
Journal: AIDS (London, England) 20040409
Title: GW433908/ritonavir once daily in antiretroviral therapy-naive HIV-infected patients: absence of protease resistance at 48 weeks.
Journal: AIDS (London, England) 20040305
Title: Preclinical pharmacology and pharmacokinetics of GW433908, a water-soluble prodrug of the human immunodeficiency virus protease inhibitor amprenavir.
Journal: Antimicrobial agents and chemotherapy 20040301
Title: Fosamprenavir: a new PI option. Interview by Craig Sterritt.
Journal: IAPAC monthly 20040201
Title: Six-week randomized controlled trial to compare the tolerabilities, pharmacokinetics, and antiviral activities of GW433908 and amprenavir in human immunodeficiency virus type 1-infected patients.
Journal: Antimicrobial agents and chemotherapy 20040101
Title: The NEAT study: a 48-week open-label study to compare the antiviral efficacy and safety of GW433908 versus nelfinavir in antiretroviral therapy-naive HIV-1-infected patients.
Journal: Journal of acquired immune deficiency syndromes (1999) 20040101
Title: FDA grants approval to fosamprenavir calcium.
Journal: AIDS alert 20040101
Title: Initial therapy for human immunodeficiency virus: broadening the options.
Journal: HIV clinical trials 20040101
Title: Peptidomimetic inhibitors of HIV protease.
Journal: Current topics in medicinal chemistry 20040101
Title: Fosamprenavir: a review of its use in the management of antiretroviral therapy-naive patients with HIV infection.
Journal: Drugs 20040101
Title: Anti-HIV agents. Saquinavir with fosamprenavir.
Journal: TreatmentUpdate 20040101
Title: [Are all boosted protease inhibitors the same? Previously treated patients profit too from lopinavir/r].
Journal: MMW Fortschritte der Medizin 20031211
Title: The continuing evolution of HIV therapy.
Journal: The AIDS reader 20031201
Title: Drug profile: fosamprenavir (Lexiva).
Journal: The Hopkins HIV report : a bimonthly newsletter for healthcare providers 20031101
Title: FDA approves Lexiva.
Journal: IAPAC monthly 20031101
Title: Lexiva (fosamprenavir) approved.
Journal: AIDS treatment news 20031031
Title: Development of water-soluble prodrugs of the HIV-1 protease inhibitor KNI-727: importance of the conversion time for higher gastrointestinal absorption of prodrugs based on spontaneous chemical cleavage.
Journal: Journal of medicinal chemistry 20030911
Title: Viral patterns of unboosted 908 identified.
Journal: AIDS patient care and STDs 20030801
Title: Reviving protease inhibitors: new data and more options.
Journal: Journal of acquired immune deficiency syndromes (1999) 20030601
Title: [Potent new protease inhibitor. Boostered protease inhibitors--a separate class of drugs].
Journal: MMW Fortschritte der Medizin 20030428
Title: [No selection of mutations. 908 raises genetic resistance barrier].
Journal: MMW Fortschritte der Medizin 20030428
Title: SOLO trial results released.
Journal: AIDS patient care and STDs 20030201
Title: Five new drugs enter the homestretch.
Journal: GMHC treatment issues : the Gay Men's Health Crisis newsletter of experimental AIDS therapies 20021201
Title: NEAT trial releases results.
Journal: AIDS patient care and STDs 20021201
Title: Effects of formulation and dosing strategy on amprenavir concentrations in the seminal plasma of human immunodeficiency virus type 1-infected men.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020915
Title: Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers.
Journal: Journal of clinical pharmacology 20020801
Title: Fosamprenavir. Vertex Pharmaceuticals/GlaxoSmithKline.
Journal: Current opinion in investigational drugs (London, England : 2000) 20020301
Title: From amprenavir to GW433908.
Journal: Journal of HIV therapy 20011101
Title: Phase III trials for new PI.
Journal: AIDS patient care and STDs 20010301
Title: New antiretroviral agents.
Journal: The Hopkins HIV report : a bimonthly newsletter for healthcare providers 20010301
Title: Falcoz C, et al. Pharmacokinetics of GW433908, a prodrug of amprenavir, in healthy male volunteers. J Clin Pharmacol. 2002 Aug;42(8):887-98.