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478482-75-6,MFCD04974171
Catalog No.:AA006YLV

478482-75-6 | GSK-3 Inhibitor II

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
≥95%
in stock  
$133.00   $93.00
- +
10mg
≥95%
in stock  
$252.00   $176.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA006YLV
Chemical Name:
GSK-3 Inhibitor II
CAS Number:
478482-75-6
Molecular Formula:
C14H10IN3OS
Molecular Weight:
395.2182
MDL Number:
MFCD04974171
SMILES:
Ic1cccc(c1)CSc1nnc(o1)c1ccncc1
Properties
Computed Properties
 
Complexity:
304  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
20  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
4  
XLogP3:
2.6  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,2012,vol.55,p.4407-4424

[2]BioorganicandMedicinalChemistryLetters,2014,vol.24,p.1532-1537

[3]Patent:US2015/210679,2015,A1.Locationinpatent:Paragraph0091;0092;0093

Literature

Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

Journal: The Biochemical journal 20130415

Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Journal: Nature biotechnology 20111101

Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Journal: Proceedings of the National Academy of Sciences of the United States of America 20071218

Title: Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20020603

Quotation Request
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SDS
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Tags:478482-75-6 Molecular Formula|478482-75-6 MDL|478482-75-6 SMILES|478482-75-6 GSK-3 Inhibitor II
Catalog No.: AA006YLV
478482-75-6,MFCD04974171
478482-75-6 | GSK-3 Inhibitor II
Pack Size： 5mg
Purity： ≥95%
in stock
$133.00 $93.00
Pack Size： 10mg
Purity： ≥95%
in stock
$252.00 $176.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA006YLV
Chemical Name: GSK-3 Inhibitor II
CAS Number: 478482-75-6
Molecular Formula: C14H10IN3OS
Molecular Weight: 395.2182
MDL Number: MFCD04974171
SMILES: Ic1cccc(c1)CSc1nnc(o1)c1ccncc1
Properties
Complexity: 304  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 20  
Hydrogen Bond Acceptor Count: 5  
Rotatable Bond Count: 4  
XLogP3: 2.6  
Downstream Synthesis Route
49617-83-6    15264-63-8    478482-75-6 

[1]JournalofMedicinalChemistry,2012,vol.55,p.4407-4424

[2]BioorganicandMedicinalChemistryLetters,2014,vol.24,p.1532-1537

[3]Patent:US2015/210679,2015,A1.Locationinpatent:Paragraph0091;0092;0093

Literature fold

Title: A broad activity screen in support of a chemogenomic map for kinase signalling research and drug discovery.

Journal: The Biochemical journal20130415

Title: Comprehensive assay of kinase catalytic activity reveals features of kinase inhibitor selectivity.

Journal: Nature biotechnology20111101

Title: A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.

Journal: Proceedings of the National Academy of Sciences of the United States of America20071218

Title: Scaffold hopping and optimization towards libraries of glycogen synthase kinase-3 inhibitors.

Journal: Bioorganic & medicinal chemistry letters20020603

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