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471-87-4,MFCD09837899
Catalog No.:AA0071IJ

471-87-4 | (S)-1,1-Dimethylpyrrolidin-1-ium-2-carboxylate

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1mg
95%
in stock  
$7.00   $5.00
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100mg
95%
in stock  
$58.00   $41.00
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250mg
95%
in stock  
$103.00   $72.00
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0071IJ
Chemical Name:
(S)-1,1-Dimethylpyrrolidin-1-ium-2-carboxylate
CAS Number:
471-87-4
Molecular Formula:
C7H13NO2
Molecular Weight:
143.1836
MDL Number:
MFCD09837899
SMILES:
[O-]C(=O)[C@@H]1CCC[N+]1(C)C
Properties
Computed Properties
 
Complexity:
148  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
10  
Hydrogen Bond Acceptor Count:
2  
XLogP3:
1  

Literature

Title: Prediction and biochemical demonstration of a catabolic pathway for the osmoprotectant proline betaine.

Journal: mBio 20140101

Title: Quaternary ammonium oxidative demethylation: X-ray crystallographic, resonance Raman, and UV-visible spectroscopic analysis of a Rieske-type demethylase.

Journal: Journal of the American Chemical Society 20120208

Title: Occurrence of pipecolic acid and pipecolic acid betaine (homostachydrine) in Citrus genus plants.

Journal: Journal of agricultural and food chemistry 20120111

Title: In vitro anticancer activity of stachydrine isolated from Capparis decidua on prostate cancer cell lines.

Journal: Natural product research 20120101

Title: Six alkaloids inhibit secretion of IL-1α, TXB(2), ET-1 and E-selectin in LPS-induced endothelial cells.

Journal: Immunological investigations 20120101

Title: Betaines in fruits of Citrus genus plants.

Journal: Journal of agricultural and food chemistry 20110914

Title: Proline betaine and its biotransformation products in fasting urine samples are potential biomarkers of habitual citrus fruit consumption.

Journal: The British journal of nutrition 20110901

Title: Arg149 is involved in switching the low affinity, open state of the binding protein AfProX into its high affinity, closed state.

Journal: Journal of molecular biology 20110805

Title: Prediction of variability in CYP3A4 induction using a combined 1H NMR metabonomics and targeted UPLC-MS approach.

Journal: Journal of proteome research 20110603

Title: Determination of betaines in vegetable oils by capillary electrophoresis tandem mass spectrometry--application to the detection of olive oil adulteration with seed oils.

Journal: Electrophoresis 20110601

Title: Anti-arthritic active fraction of Capparis spinosa L. fruits and its chemical constituents.

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 20110301

Title: Metabolic profiling strategy for discovery of nutritional biomarkers: proline betaine as a marker of citrus consumption.

Journal: The American journal of clinical nutrition 20100801

Title: Stachydrine, a major constituent of the Chinese herb leonurus heterophyllus sweet, ameliorates human umbilical vein endothelial cells injury induced by anoxia-reoxygenation.

Journal: The American journal of Chinese medicine 20100101

Title: Negative evidence for stachydrine or Galeopsis ladanum L. seeds as the causal agents of coturnism after quail meat ingestion.

Journal: Journal of agricultural and food chemistry 20091125

Title: Identification of anti-asthmatic compounds in Pericarpium citri reticulatae and evaluation of their synergistic effects.

Journal: Acta pharmacologica Sinica 20090501

Title: Effects of orange juice and proline betaine on glycine betaine and homocysteine in healthy male subjects.

Journal: European journal of nutrition 20071201

Title: [Experimental studies on compound Duzhong Jiangya prescription by semi-bionic extraction].

Journal: Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica 20071101

Title: Overexpression of BetS, a Sinorhizobium meliloti high-affinity betaine transporter, in bacteroids from Medicago sativa nodules sustains nitrogen fixation during early salt stress adaptation.

Journal: Molecular plant-microbe interactions : MPMI 20060801

Title: Fluorination-free synthesis of a 4,4-difluoro-3,3-dimethylproline derivative.

Journal: The Journal of organic chemistry 20060721

Title: [HPLC-ESI/MS analysis of stachydrine and its metabolites in rat urine].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20060501

Title: Molecular determinants for substrate specificity of the ligand-binding protein OpuAC from Bacillus subtilis for the compatible solutes glycine betaine and proline betaine.

Journal: Journal of molecular biology 20060324

Title: Combined solid-phase/solution synthesis of large ribonuclease A C-terminal peptides containing a non-natural proline analog.

Journal: The journal of peptide research : official journal of the American Peptide Society 20050601

Title: Structural basis for the binding of compatible solutes by ProX from the hyperthermophilic archaeon Archaeoglobus fulgidus.

Journal: The Journal of biological chemistry 20041112

Title: [Determination of stachydrine and leonurine in Herba Leonuri by ion- pair reversed-phase high-performance liquid chromatography].

Journal: Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA 20041101

Title: Proline betaine accumulation and metabolism in alfalfa plants under sodium chloride stress. Exploring its compartmentalization in nodules.

Journal: Plant physiology 20040701

Title: Cation-pi interactions as determinants for binding of the compatible solutes glycine betaine and proline betaine by the periplasmic ligand-binding protein ProX from Escherichia coli.

Journal: The Journal of biological chemistry 20040213

Title: Protein prosthesis: a nonnatural residue accelerates folding and increases stability.

Journal: Journal of the American Chemical Society 20030625

Title: A convenient incorporation of conformationally constrained 5,5-dimethylproline into the ribonuclease A 89-124 sequence by condensation of synthetic peptide fragments.

Journal: The journal of peptide research : official journal of the American Peptide Society 20030301

Title: Purification, crystallization and preliminary crystallographic analysis of the periplasmic binding protein ProX from Escherichia coli.

Journal: Acta crystallographica. Section D, Biological crystallography 20010301

Title: Discrimination between orange juice and pulp wash by (1)H Nuclear Magnetic Resonance spectroscopy: identification of marker compounds.

Journal: Journal of agricultural and food chemistry 20010201

Title: Guo W, et al. Effect of Leonurus stachydrine on myocardial cell hypertrophy. Zhong Yao Cai. 2012 Jun;35(6):940-3.

Title: Yin J, et al. Stachydrine, a major constituent of the Chinese herb leonurus heterophyllus sweet, ameliorates human umbilical vein endothelial cells injury induced by anoxia-reoxygenation. Am J Chin Med. 2010;38(1):157-71.

Title: Rathee P, et al. In vitro anticancer activity of stachydrine isolated from Capparis decidua on prostate cancer cell lines. Nat Prod Res. 2012;26(18):1737-40.

Title: Zhang C, et al. Effects of stachydrine on norepinephrine-induced neonatal rat cardiac myocytes hypertrophy and intracellular calcium transients. BMC Complement Altern Med. 2014 Dec 8;14:474.

Title: Zhang C, et al. Effect of stachydrine on endoplasmic reticulum stress-induced apoptosis in rat kidney after unilateral ureteral obstruction. J Asian Nat Prod Res. 2013;15(4):373-81.

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