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Title: Inhibition of Protein Ubiquitination by Paraquat and 1-Methyl-4-Phenylpyridinium Impairs Ubiquitin-Dependent Protein Degradation Pathways.

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Title: The Role of Lipin-1 in the Regulation of Fibrogenesis and TGF-β Signaling in Hepatic Stellate Cells.

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Title: The coffee diterpene kahweol suppresses the cell proliferation by inducing cyclin D1 proteasomal degradation via ERK1/2, JNK and GKS3β-dependent threonine-286 phosphorylation in human colorectal cancer cells.

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Title: Tetrachlorobenzoquinone induces Nrf2 activation via rapid Bach1 nuclear export/ubiquitination and JNK-P62 signaling.

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Title: Therapeutic targeting of BET bromodomain protein, Brd4, delays cyst growth in ADPKD.

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Title: Niclosamide inhibits androgen receptor variants expression and overcomes enzalutamide resistance in castration-resistant prostate cancer.

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Title: Analysis of possible mechanisms accounting for raf-1 kinase inhibitor protein downregulation in hepatocellular carcinoma.

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Title: The Arabidopsis F-box protein AtFBS1 interacts with 14-3-3 proteins.

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Title: p23 co-chaperone protects the aryl hydrocarbon receptor from degradation in mouse and human cell lines.

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Title: Human TSC-associated renal angiomyolipoma cells are hypersensitive to ER stress.

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Title: Naringin attenuates EGF-induced MUC5AC secretion in A549 cells by suppressing the cooperative activities of MAPKs-AP-1 and IKKs-IκB-NF-κB signaling pathways.

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Title: DJ-1 protein protects dopaminergic neurons against 6-OHDA/MG-132-induced neurotoxicity in rats.

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Title: Leishmanicidal activities and cytotoxicities of bisnaphthoquinone analogues and naphthol derivatives from Burman Diospyros burmanica.

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Title: Pretreatment with proteasome inhibitors protects against oxidative injuries via PPARα-dependent and -independent pathways in ARPE-19 cells.

Journal: Investigative ophthalmology & visual science20120831

Title: Baicalein protects against 6-OHDA-induced neurotoxicity through activation of Keap1/Nrf2/HO-1 and involving PKCα and PI3K/AKT signaling pathways.

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Title: Post-transcriptional divergence in the regulation of CAT-2A, CAT-2B and iNOS expression by dexamethasone in vascular smooth muscle cells.

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Title: The proteasome inhibitor MG132 potentiates TRAIL receptor agonist-induced apoptosis by stabilizing tBid and Bik in human head and neck squamous cell carcinoma cells.

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Title: Apolipoprotein A-I mimetic peptides inhibit expression and activity of hypoxia-inducible factor-1α in human ovarian cancer cell lines and a mouse ovarian cancer model.

Journal: The Journal of pharmacology and experimental therapeutics20120801

Title: Statins and downstream inhibitors of the isoprenylation pathway increase type 2 iodothyronine deiodinase activity.

Journal: Endocrinology20120801

Title: Infrasonic noise induces axonal degeneration of cultured neurons via a Ca²⁺ influx pathway.

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Title: Hemerythrin-like domain within F-box and leucine-rich repeat protein 5 (FBXL5) communicates cellular iron and oxygen availability by distinct mechanisms.

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Title: MG132 alleviates liver injury induced by intestinal ischemia/reperfusion in rats: involvement of the AhR and NFκB pathways.

Journal: The Journal of surgical research20120701

Title: Noxa/Mcl-1 balance influences the effect of the proteasome inhibitor MG-132 in combination with anticancer agents in pancreatic cancer cell lines.

Journal: Anti-cancer drugs20120701

Title: SIRT1 inhibits proliferation of pancreatic cancer cells expressing pancreatic adenocarcinoma up-regulated factor (PAUF), a novel oncogene, by suppression of β-catenin.

Journal: Biochemical and biophysical research communications20120629

Title: Sphingosine 1-phosphate antagonizes the effect of all-trans retinoic acid (ATRA) in a human colon cancer cell line by modulation of RARβ expression.

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Title: Activity-dependent growth of new dendritic spines is regulated by the proteasome.

Journal: Neuron20120621

Title: Sodium arsenite down-regulates the expression of X-linked inhibitor of apoptosis protein via translational and post-translational mechanisms in hepatocellular carcinoma.

Journal: Biochemical and biophysical research communications20120615

Title: A role of Rab7 in stabilizing EGFR-Her2 and in sustaining Akt survival signal.

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Title: Degradation of mouse NTE-related esterase by macroautophagy and the proteasome.

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Title: Sustained intrahepatic glutathione depletion causes proteasomal degradation of multidrug resistance-associated protein 2 in rat liver.

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Title: Agents that stabilize mutated von Hippel-Lindau (VHL) protein: results of a high-throughput screen to identify compounds that modulate VHL proteostasis.

Journal: Journal of biomolecular screening20120601

Title: Androgen deprivation causes truncation of the C-terminal region of androgen receptor in human prostate cancer LNCaP cells.

Journal: Cancer science20120601

Title: Lamin misexpression upregulates three distinct ubiquitin ligase systems that degrade ATR kinase in HeLa cells.

Journal: Molecular and cellular biochemistry20120601

Title: Evidence that aberrant protein metabolism contributes to chemoresistance in multiple myeloma cells.

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Title: Misfolded Gβ is recruited to cytoplasmic dynein by Nudel for efficient clearance.

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Title: ω-6 lipids regulate PPAR turnover via reciprocal switch between PGC-1 alpha and ubiquitination.

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Title: Auxin activates the plasma membrane H+-ATPase by phosphorylation during hypocotyl elongation in Arabidopsis.

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Title: N- and C-terminal degradation of ecdysteroid receptor isoforms, when transiently expressed in mammalian CHO cells, is regulated by the proteasome and cysteine and threonine proteases.

Journal: Insect molecular biology20120601

Title: Diphenylarsinic acid promotes degradation of glutaminase C by mitochondrial Lon protease.

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Title: Potential role of 20S proteasome in maintaining stem cell integrity of human bone marrow stromal cells in prolonged culture expansion.

Journal: Biochemical and biophysical research communications20120525

Title: Osthole inhibits the invasive ability of human lung adenocarcinoma cells via suppression of NF-κB-mediated matrix metalloproteinase-9 expression.

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Title: RhoBTB3 interacts with the 5-HT7a receptor and inhibits its proteasomal degradation.

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Title: Neddylation positively regulates the ubiquitin E3 ligase activity of parkin.

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Title: Thiostrepton is an inducer of oxidative and proteotoxic stress that impairs viability of human melanoma cells but not primary melanocytes.

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Title: The 19S proteasome subunit Rpn7 stabilizes DNA damage foci upon genotoxic insult.

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Title: Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.

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Title: Quercetin enhancement of arsenic-induced apoptosis via stimulating ROS-dependent p53 protein ubiquitination in human HaCaT keratinocytes.

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Title: High sensitivity of embryonic stem cells to proteasome inhibitors correlates with low expression of heat shock protein and decrease of pluripotent cell marker expression.

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Title: p38γ mitogen-activated protein kinase (MAPK) confers breast cancer hormone sensitivity by switching estrogen receptor (ER) signaling from classical to nonclassical pathway via stimulating ER phosphorylation and c-Jun transcription.

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Title: A role for the calmodulin kinase II-related anchoring protein (αkap) in maintaining the stability of nicotinic acetylcholine receptors.

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Title: SUMO-2/3 conjugates accumulating under heat shock or MG132 treatment result largely from new protein synthesis.

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Title: Arsenic decreases RXRα-dependent transcription of CYP3A and suppresses immune regulators in hepatocytes.

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Title: Ubiquitin/proteasome-mediated proteolysis is involved in the response to flooding stress in soybean roots, independent of oxygen limitation.

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Title: Rapid downregulation of cyclin D1 induced by geranylgeranoic acid in human hepatoma cells.

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Title: Effects of phosphatase and proteasome inhibitors on Borealin phosphorylation and degradation.

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Title: HSPA2 overexpression protects V79 fibroblasts against bortezomib-induced apoptosis.

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Title: Mutation of Glu521 or Glu535 in cytoplasmic loop 5 causes differential misfolding in multiple domains of multidrug and organic anion transporter MRP1 (ABCC1).

Journal: The Journal of biological chemistry20120302

Title: Sodium arsenite and cadmium chloride induction of proteasomal inhibition and HSP accumulation in Xenopus laevis A6 kidney epithelial cells.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20120301

Title: Identification of HSP90 as a new GABARAPL1 (GEC1)-interacting protein.

Journal: Biochimie20120301

Title: Type I interferons directly down-regulate BCL-6 in primary and transformed germinal center B cells: differential regulation in B cell lines derived from endemic or sporadic Burkitt's lymphoma.

Journal: Cytokine20120301

Title: The Ubiquitin ligase Ubr11 is essential for oligopeptide utilization in the fission yeast Schizosaccharomyces pombe.

Journal: Eukaryotic cell20120301

Title: Presenilin-2 regulates the degradation of RBP-Jk protein through p38 mitogen-activated protein kinase.

Journal: Journal of cell science20120301

Title: 4-Hydroxynonenal differentially regulates adiponectin gene expression and secretion via activating PPARγ and accelerating ubiquitin-proteasome degradation.

Journal: Molecular and cellular endocrinology20120226

Title: Proteasome inhibition-induced p38 MAPK/ERK signaling regulates autophagy and apoptosis through the dual phosphorylation of glycogen synthase kinase 3β.

Journal: Biochemical and biophysical research communications20120224

Title: Dephosphorylation-induced ubiquitination and degradation of FMRP in dendrites: a role in immediate early mGluR-stimulated translation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20120222

Title: Inhibitory activity of eudesmane sesquiterpenes from Alpinia oxyphylla on production of nitric oxide.

Journal: Bioorganic & medicinal chemistry letters20120215

Title: Reduced NKG2D ligand expression in hepatocellular carcinoma correlates with early recurrence.

Journal: Journal of hepatology20120201

Title: c-Myc down-regulation is involved in proteasome inhibitor-mediated enhancement of radiotherapeutic efficacy in non-small cell lung cancer.

Journal: International journal of oncology20120201

Title: The F-box protein CPR1/CPR30 negatively regulates R protein SNC1 accumulation.

Journal: The Plant journal : for cell and molecular biology20120201

Title: Reactive oxygen species and PI3K/Akt signaling play key roles in the induction of Nrf2-driven heme oxygenase-1 expression in sulforaphane-treated human mesothelioma MSTO-211H cells.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20120201

Title: Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association20120201

Title: PP2A phosphatase suppresses function of the mesenchymal invasion regulator NEDD9.

Journal: Biochimica et biophysica acta20120201

Title: Green tea polyphenols causes cell cycle arrest and apoptosis in prostate cancer cells by suppressing class I histone deacetylases.

Journal: Carcinogenesis20120201

Title: Synergism between arsenite and proteasome inhibitor MG132 over cell death in myeloid leukaemic cells U937 and the induction of low levels of intracellular superoxide anion.

Journal: Toxicology and applied pharmacology20120201

Title: Downregulation of Mdm2 and Mdm4 enhances viral gene expression during adenovirus infection.

Journal: Cell cycle (Georgetown, Tex.)20120201

Title: Regulated expression and role of c-Myb in the cardiovascular-directed differentiation of mouse embryonic stem cells.

Journal: Circulation research20120120

Title: Transcriptional and posttranslational inhibition of dioxin-mediated induction of CYP1A1 by harmine and harmol.

Journal: Toxicology letters20120105

Title: Involvement of suppressor of cytokine signalling-1-mediated degradation of MyD88-adaptor-like protein in the suppression of Toll-like receptor 2-mediated signalling by the murine C-type lectin SIGNR1-mediated signalling.

Journal: Cellular microbiology20120101

Title: Janus kinase 2--a novel negative regulator of estrogen receptor α function.

Journal: Cellular signalling20120101

Title: CDK1, not ERK1/2 or ERK5, is required for mitotic phosphorylation of BIMEL.

Journal: Cellular signalling20120101

Title: Quercetin-mediated Mcl-1 and survivin downregulation restores TRAIL-induced apoptosis in non-Hodgkin's lymphoma B cells.

Journal: Haematologica20120101

Title: Characterization of the Cullin7 E3 ubiquitin ligase--heterodimerization of cullin substrate receptors as a novel mechanism to regulate cullin E3 ligase activity.

Journal: Cellular signalling20120101

Title: The origin of proteasome-inhibitor resistant HLA class I peptidomes: a study with HLA-A*68:01.

Journal: Molecular & cellular proteomics : MCP20120101

Title: gp130 cytokines stimulate proteasomal degradation of tyrosine hydroxylase via extracellular signal regulated kinases 1 and 2.

Journal: Journal of neurochemistry20120101

Title: Suppression of pain and joint destruction by inhibition of the proteasome system in experimental osteoarthritis.

Journal: Pain20120101

Title: Inhibition of proteasomal proteolysis affects expression of extracellular matrix components and steroidogenesis in porcine oocyte-cumulus complexes.

Journal: Domestic animal endocrinology20120101

Title: MG132 treatment during oocyte maturation improves embryonic development after somatic cell nuclear transfer and alters oocyte and embryo transcript abundance in pigs.

Journal: Molecular reproduction and development20120101

Title: Effects of proteasome inhibitors on the nucleolar size of porcine oocytes.

Journal: The Journal of reproduction and development20120101

Title: Ubiquitin-proteasomal degradation of COX-2 in TGF-β stimulated human endometrial cells is mediated through endoplasmic reticulum mannosidase I.

Journal: Endocrinology20120101

Title: Establishment of a microplate-formatted cell-based immunoassay for rapid analysis of nucleotide excision repair ability in human primary cells.

Journal: Photochemistry and photobiology20120101

Title: Tyrosine nitration of PA700 links proteasome activation to endothelial dysfunction in mouse models with cardiovascular risk factors.

Journal: PloS one20120101

Title: Transforming growth factor-β1 suppresses hepatitis B virus replication by the reduction of hepatocyte nuclear factor-4α expression.

Journal: PloS one20120101

Title: Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development.

Journal: BMC cancer20120101

Title: Down-regulation of glucose-regulated protein (GRP) 78 potentiates cytotoxic effect of celecoxib in human urothelial carcinoma cells.

Journal: PloS one20120101

Title: Cigarette smoke affects keratinocytes SRB1 expression and localization via H2O2 production and HNE protein adducts formation.

Journal: PloS one20120101

Title: MUC1 contributes to BPDE-induced human bronchial epithelial cell transformation through facilitating EGFR activation.

Journal: PloS one20120101

Title: Small, N-terminal tags activate Parkin E3 ubiquitin ligase activity by disrupting its autoinhibited conformation.

Journal: PloS one20120101

Title: Skp2 expression unfavorably impacts survival in resectable esophageal squamous cell carcinoma.

Journal: Journal of translational medicine20120101

Title: Mechanism of chemical activation of Nrf2.

Journal: PloS one20120101

Title: Altered composition of liver proteasome assemblies contributes to enhanced proteasome activity in the exceptionally long-lived naked mole-rat.

Journal: PloS one20120101

Title: In vivo ubiquitination assay by agroinfiltration.

Journal: Methods in molecular biology (Clifton, N.J.)20120101

Title: Suppression of ribosomal function triggers innate immune signaling through activation of the NLRP3 inflammasome.

Journal: PloS one20120101

Title: Suppression of the Nrf2-dependent antioxidant response by glucocorticoids and 11β-HSD1-mediated glucocorticoid activation in hepatic cells.

Journal: PloS one20120101

Title: M-opsin protein degradation is inhibited by MG-132 in Rpe65⁻/⁻ retinal explant culture.

Journal: Molecular vision20120101

Title: Low molecular weight heparin ablates lung cancer cisplatin-resistance by inducing proteasome-mediated ABCG2 protein degradation.

Journal: PloS one20120101

Title: Phenazine methosulfate decreases HIF-1α accumulation during the exposure of cells to hypoxia.

Journal: Bioscience, biotechnology, and biochemistry20120101

Title: Critical role of heat shock protein 27 in bufalin-induced apoptosis in human osteosarcomas: a proteomic-based research.

Journal: PloS one20120101

Title: Forkhead box protein A2 (FOXA2) protein stability and activity are regulated by sumoylation.

Journal: PloS one20120101

Title: Withaferin A induces proteasome inhibition, endoplasmic reticulum stress, the heat shock response and acquisition of thermotolerance.

Journal: PloS one20120101

Title: Induction of heat shock protein 70 (Hsp70) prevents neuregulin-induced demyelination by enhancing the proteasomal clearance of c-Jun.

Journal: ASN neuro20120101

Title: Inhibition of NF-κB prevents high glucose-induced proliferation and plasminogen activator inhibitor-1 expression in vascular smooth muscle cells.

Journal: Experimental & molecular medicine20111231

Title: Anticancer efficacy of deguelin in human prostate cancer cells targeting glycogen synthase kinase-3 β/β-catenin pathway.

Journal: International journal of cancer20111215

Title: Autophagy is increased in laminin α2 chain-deficient muscle and its inhibition improves muscle morphology in a mouse model of MDC1A.

Journal: Human molecular genetics20111215

Title: NF-kappaB p65 modulates the telomerase reverse transcriptase in the HepG₂ hepatoma cell line.

Journal: European journal of pharmacology20111215

Title: p53-Independent up-regulation of a TRAIL receptor DR5 by proteasome inhibitors: a mechanism for proteasome inhibitor-enhanced TRAIL-induced apoptosis.

Journal: Biochemical and biophysical research communications20111209

Title: Proteasome inhibitors induce apoptosis and reduce viral replication in primary effusion lymphoma cells.

Journal: Biochemical and biophysical research communications20111202

Title: Q39, a quinoxaline 1,4-Di-N-oxide derivative, inhibits hypoxia-inducible factor-1α expression and the Akt/mTOR/4E-BP1 signaling pathway in human hepatoma cells.

Journal: Investigational new drugs20111201

Title: Mitogen-activated protein kinase inhibitors differently affect the growth inhibition and death of a proteasome inhibitor, MG132-treated human pulmonary fibroblast cells.

Journal: Human & experimental toxicology20111201

Title: E3 ubiquitin ligase Hades negatively regulates the exonuclear function of p53.

Journal: Cell death and differentiation20111201

Title: SAHA shows preferential cytotoxicity in mutant p53 cancer cells by destabilizing mutant p53 through inhibition of the HDAC6-Hsp90 chaperone axis.

Journal: Cell death and differentiation20111201

Title: Inhibition of ubiquitin proteasome function suppresses proliferation of pulmonary artery smooth muscle cells.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20111201

Title: Involvement of IRAKs and TRAFs in anti-β₂GPI/β₂GPI-induced tissue factor expression in THP-1 cells.

Journal: Thrombosis and haemostasis20111201

Title: Posttranslational regulation of the iron deficiency basic helix-loop-helix transcription factor FIT is affected by iron and nitric oxide.

Journal: Plant physiology20111201

Title: Clusterin is a critical downstream mediator of stress-induced YB-1 transactivation in prostate cancer.

Journal: Molecular cancer research : MCR20111201

Title: Small molecule inhibition of the steroid receptor coactivators, SRC-3 and SRC-1.

Journal: Molecular endocrinology (Baltimore, Md.)20111201

Title: Comparative study of the influence of proteasome inhibitor MG132 and ganciclovir on the cytomegalovirus-specific CD8(+) T-cell immune response.

Journal: Viral immunology20111201

Title: Proteasome inhibitors improve the function of mutant lysosomal α-glucosidase in fibroblasts from Pompe disease patient carrying c.546G>T mutation.

Journal: Biochemical and biophysical research communications20111118

Title: Proteasome inhibitors suppress expression of NPM and ARF proteins.

Journal: Cell cycle (Georgetown, Tex.)20111115

Title: A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.

Journal: Cancer cell20111115

Title: Muscle actin is polyubiquitinylated in vitro and in vivo and targeted for breakdown by the E3 ligase MuRF1.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20111101

Title: Proteasome inhibitor MG132-induced apoptosis via ER stress-mediated apoptotic pathway and its potentiation by protein tyrosine kinase p56lck in human Jurkat T cells.

Journal: Biochemical pharmacology20111101

Title: Relative contribution of different l-arginine sources to the substrate supply of endothelial nitric oxide synthase.

Journal: Journal of molecular and cellular cardiology20111101

Title: New aldehyde and vinylsulfone proteasome inhibitors for targeted melanoma therapy.

Journal: European journal of medicinal chemistry20111101

Title: Down-regulation of peroxisome proliferator-activated receptor γ coactivator-1α expression in fatty acid-induced pancreatic beta-cell apoptosis involves nuclear factor-κB pathway.

Journal: Chinese medical journal20111101

Title: Gastrodia elata prevents huntingtin aggregations through activation of the adenosine A₂A receptor and ubiquitin proteasome system.

Journal: Journal of ethnopharmacology20111031

Title: Synthesis and biological activity of optimized belactosin C congeners.

Journal: Organic & biomolecular chemistry20111026

Title: Agrobacterium counteracts host-induced degradation of its effector F-box protein.

Journal: Science signaling20111018

Title: N-(2-{3-[3,5-bis(trifluoromethyl)phenyl]ureido}ethyl)-glycyrrhetinamide (6b): a novel anticancer glycyrrhetinic acid derivative that targets the proteasome and displays anti-kinase activity.

Journal: Journal of medicinal chemistry20111013

Title: OSBP-related protein 7 interacts with GATE-16 and negatively regulates GS28 protein stability.

Journal: Experimental cell research20111001

Title: An anti-HIV-1 compound that increases steady-state expression of apoplipoprotein B mRNA-editing enzyme-catalytic polypeptide-like 3G.

Journal: International journal of molecular medicine20111001

Title: E3 ubiquitin-protein ligases in rat kidney collecting duct: response to vasopressin stimulation and withdrawal.

Journal: American journal of physiology. Renal physiology20111001

Title: Increased glucose concentration results in reduced proteasomal activity and the formation of glycogen positive aggresomal structures.

Journal: The FEBS journal20111001

Title: Assessing ubiquitination of viral proteins: Lessons from flavivirus NS5.

Journal: Methods (San Diego, Calif.)20111001

Title: Celecoxib promotes c-FLIP degradation through Akt-independent inhibition of GSK3.

Journal: Cancer research20111001

Title: Formation of stable attachments between kinetochores and microtubules depends on the B56-PP2A phosphatase.

Journal: Nature cell biology20111001

Title: Involvement of Arabidopsis NAC transcription factor in the regulation of 20S and 26S proteasomes.

Journal: Plant science : an international journal of experimental plant biology20111001

Title: A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.

Journal: Molecular & cellular proteomics : MCP20111001

Title: Mutations associated with Charcot-Marie-Tooth disease cause SIMPLE protein mislocalization and degradation by the proteasome and aggresome-autophagy pathways.

Journal: Journal of cell science20111001

Title: FoxM1 knockdown sensitizes human cancer cells to proteasome inhibitor-induced apoptosis but not to autophagy.

Journal: Cell cycle (Georgetown, Tex.)20111001

Title: SCAR mediates light-induced root elongation in Arabidopsis through photoreceptors and proteasomes.

Journal: The Plant cell20111001

Title: Cigarette smoke induces Akt protein degradation by the ubiquitin-proteasome system.

Journal: The Journal of biological chemistry20110916

Title: Curcumin enhances the mitomycin C-induced cytotoxicity via downregulation of MKK1/2-ERK1/2-mediated Rad51 expression in non-small cell lung cancer cells.

Journal: Toxicology and applied pharmacology20110915

Title: PEST motif sequence regulating human NANOG for proteasomal degradation.

Journal: Stem cells and development20110901

Title: Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells.

Journal: American journal of physiology. Cell physiology20110901

Title: An IκBα phosphorylation inhibitor induces heme oxygenase-1(HO-1) expression through the activation of reactive oxygen species (ROS)-Nrf2-ARE signaling and ROS-PI3K/Akt signaling in an NF-κB-independent mechanism.

Journal: Cellular signalling20110901

Title: Hunterian Lecture. Characterisation of human prostate epithelial progenitor differentiation in response to androgens.

Journal: Annals of the Royal College of Surgeons of England20110901

Title: Novel interactions between actin and the proteasome revealed by complex haploinsufficiency.

Journal: PLoS genetics20110901

Title: A circadian clock in hippocampus is regulated by interaction between oligophrenin-1 and Rev-erbα.

Journal: Nature neuroscience20110828

Title: A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by Aurora kinases.

Journal: Current biology : CB20110823

Title: Inducible nitric-oxide synthase and nitric oxide donor decrease insulin receptor substrate-2 protein expression by promoting proteasome-dependent degradation in pancreatic beta-cells: involvement of glycogen synthase kinase-3beta.

Journal: The Journal of biological chemistry20110819

Title: A new pathway that regulates 53BP1 stability implicates cathepsin L and vitamin D in DNA repair.

Journal: The EMBO journal20110817

Title: Proteomic signatures in thapsigargin-treated hepatoma cells.

Journal: Chemical research in toxicology20110815

Title: The effect of nNOS inhibitors on toxin-induced cell death in dopaminergic cell lines depends on the extent of enzyme expression.

Journal: Brain research20110802

Title: RGS4, a GTPase activator, improves renal function in ischemia-reperfusion injury.

Journal: Kidney international20110801

Title: Proteasome inhibitors sensitize glioma cells and glioma stem cells to TRAIL-induced apoptosis by PKCε-dependent downregulation of AKT and XIAP expressions.

Journal: Cellular signalling20110801

Title: Chemical chaperones protect epidermolysis bullosa simplex keratinocytes from heat stress-induced keratin aggregation: involvement of heat shock proteins and MAP kinases.

Journal: The Journal of investigative dermatology20110801

Title: Inhibition of HSP90-dependent telomerase activity in amyloid β-induced apoptosis of cerebral endothelial cells.

Journal: Journal of cellular physiology20110801

Title: Uraemic serum induces dysfunction of vascular endothelial cells: role of ubiquitin-proteasome pathway.

Journal: Experimental physiology20110801

Title: Apoptotic effect of MG-132 on human tongue squamous cell carcinoma.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie20110801

Title: Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase.

Journal: Parasitology20110801

Title: Inhibition of NF-κB by MG132 through ER stress-mediated induction of LAP and LIP.

Journal: FEBS letters20110721

Title: The turnover of estrogen receptor α by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy.

Journal: Biochemical pharmacology20110715

Title: The tyrosine kinase inhibitor sorafenib sensitizes hepatocellular carcinoma cells to taxol by suppressing the HURP protein.

Journal: Biochemical pharmacology20110715

Title: Intracellular colocalization of HAP1/STBs with steroid hormone receptors and its enhancement by a proteasome inhibitor.

Journal: Experimental cell research20110715

Title: Quercetin downregulates Mcl-1 by acting on mRNA stability and protein degradation.

Journal: British journal of cancer20110712

Title: Aldose reductase inhibition prevents hypoxia-induced increase in hypoxia-inducible factor-1alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF) by regulating 26 S proteasome-mediated protein degradation in human colon cancer cells.

Journal: The Journal of biological chemistry20110708

Title: Novel cell- and tissue-based assays for detecting misfolded and aggregated protein accumulation within aggresomes and inclusion bodies.

Journal: Cell biochemistry and biophysics20110701

Title: Up-regulation of extracellular signal-regulated kinase 1/2-dependent thymidylate synthase and thymidine phosphorylase contributes to cisplatin resistance in human non-small-cell lung cancer cells.

Journal: The Journal of pharmacology and experimental therapeutics20110701

Title: An overlapping reading frame in the PRNP gene encodes a novel polypeptide distinct from the prion protein.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20110701

Title: Proteasomal degradation of myocardin is required for its transcriptional activity in vascular smooth muscle cells.

Journal: Journal of cellular physiology20110701

Title: Aldo-keto reductase 1C15 as a quinone reductase in rat endothelial cell: its involvement in redox cycling of 9,10-phenanthrenequinone.

Journal: Free radical research20110701

Title: [The effect of RhoA and proteasome inhibitor MG132 on angiogenesis in tumors].

Journal: Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition20110701

Title: Sesquiterpene and norsesquiterpene derivatives from Sanicula lamelligera and their biological evaluation.

Journal: Journal of natural products20110624

Title: Bim protein degradation contributes to cisplatin resistance.

Journal: The Journal of biological chemistry20110624

Title: MG132 enhances neurite outgrowth in neurons overexpressing mutant TAR DNA-binding protein-43 via increase of HO-1.

Journal: Brain research20110623

Title: Comparative proteomic analysis identifies a role for SUMO in protein quality control.

Journal: Science signaling20110621

Title: A genetic interaction network of five genes for human polycystic kidney and liver diseases defines polycystin-1 as the central determinant of cyst formation.

Journal: Nature genetics20110619

Title: JWA regulates chronic morphine dependence via the delta opioid receptor.

Journal: Biochemical and biophysical research communications20110610

Title: Constitutive activation of metalloproteinase ADAM10 in mantle cell lymphoma promotes cell growth and activates the TNFα/NFκB pathway.

Journal: Blood20110609

Title: Prefoldin subunits are protected from ubiquitin-proteasome system-mediated degradation by forming complex with other constituent subunits.

Journal: The Journal of biological chemistry20110603

Title: Interactive expressions of HtrA1 and VEGF in human vitreous humors and fetal RPE cells.

Journal: Investigative ophthalmology & visual science20110601

Title: Classical swine fever virus NS2 protein promotes interleukin-8 expression and inhibits MG132-induced apoptosis.

Journal: Virus genes20110601

Title: Proteasome inhibition by MG132 induces growth inhibition and death of human pulmonary fibroblast cells in a caspase-independent manner.

Journal: Oncology reports20110601

Title: Garlic constituent diallyl trisulfide suppresses x-linked inhibitor of apoptosis protein in prostate cancer cells in culture and in vivo.

Journal: Cancer prevention research (Philadelphia, Pa.)20110601

Title: Glucose deprivation is associated with Chk1 degradation through the ubiquitin-proteasome pathway and effective checkpoint response to replication blocks.

Journal: Biochimica et biophysica acta20110601

Title: Arabidopsis G1 cell cycle proteins undergo proteasome-dependent degradation during sucrose starvation.

Journal: Plant physiology and biochemistry : PPB20110601

Title: Caffeine can be used for oocyte enucleation.

Journal: Cellular reprogramming20110601

Title: Offspring from intracytoplasmic sperm injection of aged mouse oocytes treated with caffeine or MG132.

Journal: Genesis (New York, N.Y. : 2000)20110601

Title: The HSP90 molecular chaperone cycle regulates cyclical transcriptional dynamics of the glucocorticoid receptor and its coregulatory molecules CBP/p300 during ultradian ligand treatment.

Journal: Molecular endocrinology (Baltimore, Md.)20110601

Title: Regulation of Notch1 signaling by the APP intracellular domain facilitates degradation of the Notch1 intracellular domain and RBP-Jk.

Journal: Journal of cell science20110601

Title: Proteasome inhibitors MG-132 and bortezomib induce AKR1C1, AKR1C3, AKR1B1, and AKR1B10 in human colon cancer cell lines SW-480 and HT-29.

Journal: Chemico-biological interactions20110530

Title: Mutant p53 protein is targeted by arsenic for degradation and plays a role in arsenic-mediated growth suppression.

Journal: The Journal of biological chemistry20110520

Title: MG132 treatment attenuates cardiac remodeling and dysfunction following aortic banding in rats via the NF-κB/TGFβ1 pathway.

Journal: Biochemical pharmacology20110515

Title: Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals.

Journal: Molecular & cellular proteomics : MCP20110501

Title: Selective involvement of BH3-only proteins and differential targets of Noxa in diverse apoptotic pathways.

Journal: Cell death and differentiation20110501

Title: N-Glycans mutations rule oligomeric assembly and functional expression of P2X3 receptor for extracellular ATP.

Journal: Glycobiology20110501

Title: The proteasome inhibitor MG-132 induces AIF nuclear translocation through down-regulation of ERK and Akt/mTOR pathway.

Journal: Neurochemical research20110501

Title: Poly(ADP-ribose) polymerase and XPF-ERCC1 participate in distinct pathways for the repair of topoisomerase I-induced DNA damage in mammalian cells.

Journal: Nucleic acids research20110501

Title: Recruitment of APPL1 to ubiquitin-rich aggresomes in response to proteasomal impairment.

Journal: Experimental cell research20110501

Title: Proteasome inhibitors induce the presentation of an Epstein-Barr virus nuclear antigen 1-derived cytotoxic T lymphocyte epitope in Burkitt's lymphoma cells.

Journal: Immunology20110501

Title: Prevention of muscle disuse atrophy by MG132 proteasome inhibitor.

Journal: Muscle & nerve20110501

Title: Proteasome inhibitor MG-132 induces C6 glioma cell apoptosis via oxidative stress.

Journal: Acta pharmacologica Sinica20110501

Title: Interaction between the bHLH transcription factor FIT and ETHYLENE INSENSITIVE3/ETHYLENE INSENSITIVE3-LIKE1 reveals molecular linkage between the regulation of iron acquisition and ethylene signaling in Arabidopsis.

Journal: The Plant cell20110501

Title: APP and APLP1 are degraded through autophagy in response to proteasome inhibition in neuronal cells.

Journal: Protein & cell20110501

Title: Ubiquitin proteasomal pathway mediated degradation of p53 in melanoma.

Journal: Archives of biochemistry and biophysics20110415

Title: Intracellular rescue of the uroporphyrinogen III synthase activity in enzymes carrying the hotspot mutation C73R.

Journal: The Journal of biological chemistry20110415

Title: Semi-high throughput method of measuring proteasome inhibition in vitro and in cultured cells.

Journal: Cell biology and toxicology20110401

Title: Reactive oxygen species regulate nucleostemin oligomerization and protein degradation.

Journal: The Journal of biological chemistry20110401

Title: Gemcitabine/cannabinoid combination triggers autophagy in pancreatic cancer cells through a ROS-mediated mechanism.

Journal: Cell death & disease20110401

Title: Contribution of hypoxia-inducible factor-1α to transcriptional regulation of vascular endothelial growth factor in bovine developing luteal cells.

Journal: Animal science journal = Nihon chikusan Gakkaiho20110401

Title: Beta-subunits promote the expression of Ca(V)2.2 channels by reducing their proteasomal degradation.

Journal: The Journal of biological chemistry20110318

Title: Prevention of diabetic nephropathy in rats through enhanced renal antioxidative capacity by inhibition of the proteasome.

Journal: Life sciences20110314

Title: Conserved intramolecular disulfide bond is critical to trafficking and fate of ATP-binding cassette (ABC) transporters ABCB6 and sulfonylurea receptor 1 (SUR1)/ABCC8.

Journal: The Journal of biological chemistry20110311

Title: Opioid-induced down-regulation of RGS4: role of ubiquitination and implications for receptor cross-talk.

Journal: The Journal of biological chemistry20110311

Title: Involvement of protein kinase D in expression and trafficking of ATP7B (copper ATPase).

Journal: The Journal of biological chemistry20110304

Title: LRRK2 mutant iPSC-derived DA neurons demonstrate increased susceptibility to oxidative stress.

Journal: Cell stem cell20110304

Title: Identification of compounds protective against G93A-SOD1 toxicity for the treatment of amyotrophic lateral sclerosis.

Journal: Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases20110301

Title: Role of the ubiquitin-proteasome system in Bombyx mori nucleopolyhedrovirus infection.

Journal: The Journal of general virology20110301

Title: Reactivation of L1 retrotransposon by benzo(a)pyrene involves complex genetic and epigenetic regulation.

Journal: Epigenetics20110301

Title: The enhancement of propyl gallate-induced apoptosis in HeLa cells by a proteasome inhibitor MG132.

Journal: Oncology reports20110301

Title: Proteasome inhibitor sensitizes oral squamous cell carcinoma cells to TRAIL-mediated apoptosis.

Journal: Oncology reports20110301

Title: HSP90 is crucial for regulation of LAT expression in activated T cells.

Journal: Molecular immunology20110301

Title: Tubular injury in a rat model of type 2 diabetes is prevented by metformin: a possible role of HIF-1α expression and oxygen metabolism.

Journal: Diabetes20110301

Title: Rapid and quantitative assessment of cell quality, identity, and functionality for cell-based assays using real-time cellular analysis.

Journal: Journal of biomolecular screening20110301

Title: Proteasome inhibition causes epithelial-mesenchymal transition upon TM4SF5 expression.

Journal: Journal of cellular biochemistry20110301

Title: Nerve growth factor-induced neurite outgrowth is potentiated by stabilization of TrkA receptors.

Journal: BMB reports20110301

Title: Gambogic acid enhances proteasome inhibitor-induced anticancer activity.

Journal: Cancer letters20110227

Title: Proteasome inhibitors induce nucleolar aggregation of proteasome target proteins and polyadenylated RNA by altering ubiquitin availability.

Journal: Oncogene20110217

Title: Calsenilin is degraded by the ubiquitin-proteasome pathway.

Journal: Biochemical and biophysical research communications20110211

Title: Acetylation and phosphorylation of SRSF2 control cell fate decision in response to cisplatin.

Journal: The EMBO journal20110202

Title: Opioid-induced chemokine expression requires NF-κB activity: the role of PKCζ.

Journal: Journal of leukocyte biology20110201

Title: NFκB inhibitors induce cell death in glioblastomas.

Journal: Biochemical pharmacology20110201

Title: Carbamazepine promotes Her-2 protein degradation in breast cancer cells by modulating HDAC6 activity and acetylation of Hsp90.

Journal: Molecular and cellular biochemistry20110201

Title: Proteasome inhibition improves the muscle of laminin α2 chain-deficient mice.

Journal: Human molecular genetics20110201

Title: Andrographolide down-regulates hypoxia-inducible factor-1α in human non-small cell lung cancer A549 cells.

Journal: Toxicology and applied pharmacology20110201

Title: Activation of brain endothelium by soluble aggregates of the amyloid-β protein involves nuclear factor-κB.

Journal: Current Alzheimer research20110201

Title: Bortezomib induces nuclear translocation of IκBα resulting in gene-specific suppression of NF-κB--dependent transcription and induction of apoptosis in CTCL.

Journal: Molecular cancer research : MCR20110201

Title: [Apoptosis induced by MG-132 in Tca-8113 cells].

Journal: Shanghai kou qiang yi xue = Shanghai journal of stomatology20110201

Title: Alcama mediates Edn1 signaling during zebrafish cartilage morphogenesis.

Journal: Developmental biology20110115

Title: Tripeptidyl peptidase II serves as an alternative to impaired proteasome to maintain viral growth in the host cells.

Journal: FEBS letters20110103

Title: The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.

Journal: Cell death and differentiation20110101

Title: Glucocorticoid-induced activation of caspase-8 protects the glucocorticoid-induced protein Gilz from proteasomal degradation and induces its binding to SUMO-1 in murine thymocytes.

Journal: Cell death and differentiation20110101

Title: Proteasome inhibition induces developmentally deregulated programs of apoptotic and autophagic cell death during Drosophila melanogaster oogenesis.

Journal: Cell biology international20110101

Title: Inhibition of all-trans-retinoic acid-induced proteasome activation potentiates the differentiating effect of retinoid in acute myeloid leukemia cells.

Journal: Molecular carcinogenesis20110101

Title: The mammalian target of rapamycin inhibitor RAD001 (everolimus) synergizes with chemotherapeutic agents, ionizing radiation and proteasome inhibitors in pre-B acute lymphocytic leukemia.

Journal: Haematologica20110101

Title: MG132, a proteasome inhibitor-induced calf pulmonary arterial endothelial cell growth and death, are changed by MAPK inhibitors.

Journal: Drug and chemical toxicology20110101

Title: Influence of Hsp90 and HDAC inhibition and tubulin acetylation on perinuclear protein aggregation in human retinal pigment epithelial cells.

Journal: Journal of biomedicine & biotechnology20110101

Title: Tuberous sclerosis-2 (TSC2) regulates the stability of death-associated protein kinase-1 (DAPK) through a lysosome-dependent degradation pathway.

Journal: The FEBS journal20110101

Title: Fates-shifted is an F-box protein that targets Bicoid for degradation and regulates developmental fate determination in Drosophila embryos.

Journal: Nature cell biology20110101

Title: Effects of proteasome inhibitors on rat renal fibrosis in vitro and in vivo.

Journal: Nephrology (Carlton, Vic.)20110101

Title: Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression.

Journal: Molecular cancer20110101

Title: Modulation of TRAIL resistance in colon carcinoma cells: different contributions of DR4 and DR5.

Journal: BMC cancer20110101

Title: Proteasome inhibition alleviates prolonged moderate compression-induced muscle pathology.

Journal: BMC musculoskeletal disorders20110101

Title: Quantitative proteomics identifies the Myb-binding protein p160 as a novel target of the von Hippel-Lindau tumor suppressor.

Journal: PloS one20110101

Title: Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts.

Journal: PloS one20110101

Title: Effect of inhibition of the ubiquitin-proteasome-system and IκB kinase on airway inflammation and hyperresponsiveness in a murine model of asthma.

Journal: International journal of immunopathology and pharmacology20110101

Title: Production of free methylarginines via the proteasome and autophagy pathways in cultured cells.

Journal: Molecular medicine reports20110101

Title: Structure-function analysis of STRUBBELIG, an Arabidopsis atypical receptor-like kinase involved in tissue morphogenesis.

Journal: PloS one20110101

Title: Staphylococcus aureus regulates secretion of interleukin-6 and monocyte chemoattractant protein-1 through activation of nuclear factor kappaB signaling pathway in human osteoblasts.

Journal: The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases20110101

Title: Systemic analysis of heat shock response induced by heat shock and a proteasome inhibitor MG132.

Journal: PloS one20110101

Title: [Critical amino acids of ornitin decarboxylase degron: the presence and C-terminal arrangement is insufficient for alfa-fetoprotein degradation].

Journal: Molekuliarnaia biologiia20110101

Title: Cytoplasmic accumulation and aggregation of TDP-43 upon proteasome inhibition in cultured neurons.

Journal: PloS one20110101

Title: The proteasome inhibitor MG132 reduces immobilization-induced skeletal muscle atrophy in mice.

Journal: BMC musculoskeletal disorders20110101

Title: Eukaryotic cells producing ribosomes deficient in Rpl1 are hypersensitive to defects in the ubiquitin-proteasome system.

Journal: PloS one20110101

Title: The von Hippel-Lindau tumor suppressor protein promotes c-Cbl-independent poly-ubiquitylation and degradation of the activated EGFR.

Journal: PloS one20110101

Title: The docking protein p130Cas regulates cell sensitivity to proteasome inhibition.

Journal: BMC biology20110101

Title: Possible linkage of SP6 transcriptional activity with amelogenesis by protein stabilization.

Journal: Journal of biomedicine & biotechnology20110101

Title: Substrate-favored lysosomal and proteasomal pathways participate in the normal balance control of insulin precursor maturation and disposal in β-cells.

Journal: PloS one20110101

Title: A single bivalent efficiently inhibits cyclin B1 degradation and polar body extrusion in mouse oocytes indicating robust SAC during female meiosis I.

Journal: PloS one20110101

Title: Postnatal proteasome inhibition induces neurodegeneration and cognitive deficiencies in adult mice: a new model of neurodevelopment syndrome.

Journal: PloS one20110101

Title: Adriamycin enhances proteasome-mediated generation of the proapoptotic processed form of MAGE-A4 in hepatoma cells.

Journal: Oncology20110101

Title: A noncompetitive small molecule inhibitor of estrogen-regulated gene expression and breast cancer cell growth that enhances proteasome-dependent degradation of estrogen receptor {alpha}.

Journal: The Journal of biological chemistry20101231

Title: Phosphorylated alpha-synuclein at Ser-129 is targeted to the proteasome pathway in a ubiquitin-independent manner.

Journal: The Journal of biological chemistry20101224

Title: Regulation of PTEN stability and activity by Plk3.

Journal: The Journal of biological chemistry20101217

Title: Regulation of ΔNp63α by NFκΒ.

Journal: Cell cycle (Georgetown, Tex.)20101215

Title: Identification of the aryl hydrocarbon receptor target gene TiPARP as a mediator of suppression of hepatic gluconeogenesis by 2,3,7,8-tetrachlorodibenzo-p-dioxin and of nicotinamide as a corrective agent for this effect.

Journal: The Journal of biological chemistry20101210

Title: Tumor necrosis factor alpha-induced inflammation is increased but apoptosis is inhibited by common food additive carrageenan.

Journal: The Journal of biological chemistry20101210

Title: An ERK-dependent pathway to Noxa expression regulates apoptosis by platinum-based chemotherapeutic drugs.

Journal: Oncogene20101209

Title: 1α, 25-Dihydroxyvitamin D regulates hypoxia-inducible factor-1α in untransformed and Harvey-ras transfected breast epithelial cells.

Journal: Cancer letters20101208

Title: Oxaliplatin down-regulates survivin by p38 MAP kinase and proteasome in human colon cancer cells.

Journal: Chemico-biological interactions20101205

Title: Lysine 419 targets human glucocorticoid receptor for proteasomal degradation.

Journal: Steroids20101201

Title: Modulation of hypoxia-inducible factor-1α expression by mitochondrial NADP+-dependent isocitrate dehydrogenase.

Journal: Biochimie20101201

Title: Physiological levels of ATP negatively regulate proteasome function.

Journal: Cell research20101201

Title: Inhibition of the ubiquitin-proteasome system leads to delay of the onset of ZGA gene expression.

Journal: The Journal of reproduction and development20101201

Title: Metabolism and action of proteasome inhibitors in primary human hepatocytes.

Journal: Drug metabolism and disposition: the biological fate of chemicals20101201

Title: p53 and PPP1R13L (alias iASPP or RAI) form a feedback loop to regulate genotoxic stress responses.

Journal: Biochimica et biophysica acta20101201

Title: Mineralocorticoid receptor degradation is promoted by Hsp90 inhibition and the ubiquitin-protein ligase CHIP.

Journal: American journal of physiology. Renal physiology20101201

Title: Nuclear remodeling in bovine somatic cell nuclear transfer embryos using MG132-treated recipient oocytes.

Journal: Cellular reprogramming20101201

Title: Radioimmunotherapy with an antibody to the HPV16 E6 oncoprotein is effective in an experimental cervical tumor expressing low levels of E6.

Journal: Cancer biology & therapy20101115

Title: Sulforaphane activates heat shock response and enhances proteasome activity through up-regulation of Hsp27.

Journal: The Journal of biological chemistry20101112

Title: Cadmium impairs albumin reabsorption by down-regulating megalin and ClC5 channels in renal proximal tubule cells.

Journal: Environmental health perspectives20101101

Title: Combined chemical and genetic approach to inhibit proteolysis by the proteasome.

Journal: Yeast (Chichester, England)20101101

Title: Autophagy is activated by proteasomal inhibition and involved in aggresome clearance in cultured astrocytes.

Journal: Glia20101101

Title: Asian ginseng extract inhibits in vitro and in vivo growth of mouse lewis lung carcinoma via modulation of ERK-p53 and NF-κB signaling.

Journal: Journal of cellular biochemistry20101101

Title: Regulation of intracellular decorin via proteasome degradation in rat mesangial cells.

Journal: Journal of cellular biochemistry20101101

Title: Selective vulnerability of neurons to acute toxicity after proteasome inhibitor treatment: implications for oxidative stress and insolubility of newly synthesized proteins.

Journal: Free radical biology & medicine20101101

Title: NF-kappaB regulates the expression of Nucling, a novel apoptosis regulator, with involvement of proteasome and caspase for its degradation.

Journal: Journal of biochemistry20101101

Title: Insulin stimulation of PKCδ triggers its rapid degradation via the ubiquitin-proteasome pathway.

Journal: Biochimica et biophysica acta20101101

Title: Implication of oxygen-regulated protein 150 (ORP150) in apoptosis induced by proteasome inhibitors in human thyroid cancer cells.

Journal: The Journal of clinical endocrinology and metabolism20101101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters20101101

Title: Regulation of human carbonyl reductase 3 (CBR3; SDR21C2) expression by Nrf2 in cultured cancer cells.

Journal: Biochemistry20101005

Title: Reactive oxygen species and glutathione level changes by a proteasome inhibitor, MG132, partially affect calf pulmonary arterial endothelial cell death.

Journal: Drug and chemical toxicology20101001

Title: Treatment with p38 inhibitor intensifies the death of MG132-treated As4.1 juxtaglomerular cells via the enhancement of GSH depletion.

Journal: Drug and chemical toxicology20101001

Title: p62 (SQSTM1) and cyclic AMP phosphodiesterase-4A4 (PDE4A4) locate to a novel, reversible protein aggregate with links to autophagy and proteasome degradation pathways.

Journal: Cellular signalling20101001

Title: Proteasome inhibition modeling nigral neuron degeneration in Parkinson's disease.

Journal: Journal of neurochemistry20101001

Title: Resveratrol improves left ventricular diastolic relaxation in type 2 diabetes by inhibiting oxidative/nitrative stress: in vivo demonstration with magnetic resonance imaging.

Journal: American journal of physiology. Heart and circulatory physiology20101001

Title: Butein suppresses the expression of nuclear factor-kappa B-mediated matrix metalloproteinase-9 and vascular endothelial growth factor in prostate cancer cells.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20101001

Title: Downregulation of active caspase 8 as a mechanism of acquired TRAIL resistance in mismatch repair-proficient colon carcinoma cell lines.

Journal: International journal of oncology20101001

Title: Programmed cell death of the megagametophyte during post-germinative growth of white spruce (Picea glauca) seeds is regulated by reactive oxygen species and the ubiquitin-mediated proteolytic system.

Journal: Plant & cell physiology20101001

Title: Troglitazone induces cytotoxicity in part by promoting the degradation of peroxisome proliferator-activated receptor γ co-activator-1α protein.

Journal: British journal of pharmacology20101001

Title: Short hairpin RNA-mediated fibronectin knockdown delays tumor growth in a mouse glioma model.

Journal: Neoplasia (New York, N.Y.)20101001

Title: Murine double minute 2 as a modulator of retroviral restrictions mediated by TRIM5alpha.

Journal: Virology20100930

Title: Prolonged prometaphase blocks daughter cell proliferation despite normal completion of mitosis.

Journal: Current biology : CB20100928

Title: Activation of Nrf2 by microcystin-LR provides advantages for liver cancer cell growth.

Journal: Chemical research in toxicology20100920

Title: Alpha,beta-unsaturated N-acylpyrrole peptidyl derivatives: new proteasome inhibitors.

Journal: Journal of medicinal chemistry20100909

Title: Mitochondrial remodeling following fission inhibition by 15d-PGJ2 involves molecular changes in mitochondrial fusion protein OPA1.

Journal: Biochemical and biophysical research communications20100903

Title: The Ski protein negatively regulates Siah2-mediated HDAC3 degradation.

Journal: Biochemical and biophysical research communications20100903

Title: Suppression of MG132-mediated cell death by peroxiredoxin 1 through influence on ASK1 activation in human thyroid cancer cells.

Journal: Endocrine-related cancer20100901

Title: Proteasome inhibitor MG132 reduces growth of As4.1 juxtaglomerular cells via caspase-independent apoptosis.

Journal: Archives of toxicology20100901

Title: The silencing suppressor P25 of Potato virus X interacts with Argonaute1 and mediates its degradation through the proteasome pathway.

Journal: Molecular plant pathology20100901

Title: Live-cell imaging RNAi screen identifies PP2A-B55alpha and importin-beta1 as key mitotic exit regulators in human cells.

Journal: Nature cell biology20100901

Title: Recruitment of phosphorylated NPM1 to sites of DNA damage through RNF8-dependent ubiquitin conjugates.

Journal: Cancer research20100901

Title: Activation of specific apoptotic caspases with an engineered small-molecule-activated protease.

Journal: Cell20100820

Title: Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients.

Journal: Human molecular genetics20100815

Title: Inhibition of connexin 43 gap junction channels by the endocrine disruptor ioxynil.

Journal: Toxicology and applied pharmacology20100815

Title: Protection against cellular stress by 25-hydroxyvitamin D3 in breast epithelial cells.

Journal: Journal of cellular biochemistry20100815

Title: A novel Ca2+/calmodulin antagonist HBC inhibits angiogenesis and down-regulates hypoxia-inducible factor.

Journal: The Journal of biological chemistry20100813

Title: Effect of proteasome inhibition by MG-132 on HSP27 oligomerization, phosphorylation, and aggresome formation in the OLN-93 oligodendroglia cell line.

Journal: Journal of neurochemistry20100801

Title: Proapoptotic fibronectin fragment induces the degradation of ubiquitinated p53 via proteasomes in periodontal ligament cells.

Journal: Journal of periodontal research20100801

Title: Light-induced degradation of phyA is promoted by transfer of the photoreceptor into the nucleus.

Journal: Plant molecular biology20100801

Title: Surfactant protein A2 mutations associated with pulmonary fibrosis lead to protein instability and endoplasmic reticulum stress.

Journal: The Journal of biological chemistry20100716

Title: Glucose is necessary for stabilization of hypoxia-inducible factor-1alpha under hypoxia: contribution of the pentose phosphate pathway to this stabilization.

Journal: FEBS letters20100716

Title: Temperature-sensitive post-translational regulation of plant omega-3 fatty-acid desaturases is mediated by the endoplasmic reticulum-associated degradation pathway.

Journal: The Journal of biological chemistry20100709

Title: HSP27 controls GATA-1 protein level during erythroid cell differentiation.

Journal: Blood20100708

Title: Human ROBO1 is cleaved by metalloproteinases and gamma-secretase and migrates to the nucleus in cancer cells.

Journal: FEBS letters20100702

Title: MG132 as a proteasome inhibitor induces cell growth inhibition and cell death in A549 lung cancer cells via influencing reactive oxygen species and GSH level.

Journal: Human & experimental toxicology20100701

Title: Dihydroartemisinin accelerates c-MYC oncoprotein degradation and induces apoptosis in c-MYC-overexpressing tumor cells.

Journal: Biochemical pharmacology20100701

Title: Characterization of BAG3 cleavage during apoptosis of pancreatic cancer cells.

Journal: Journal of cellular physiology20100701

Title: Functionalized aurones as inducers of NAD(P)H:quinone oxidoreductase 1 that activate AhR/XRE and Nrf2/ARE signaling pathways: synthesis, evaluation and SAR.

Journal: European journal of medicinal chemistry20100701

Title: PCB-153 exposure coordinates cell cycle progression and cellular metabolism in human mammary epithelial cells.

Journal: Toxicology letters20100701

Title: Attenuation of pain and inflammation in adjuvant-induced arthritis by the proteasome inhibitor MG132.

Journal: Arthritis and rheumatism20100701

Title: Akt associates with nuclear factor kappaB and plays an important role in chemoresistance of gastric cancer cells.

Journal: Oncology reports20100701

Title: Quercetin potentiates UVB-Induced c-Fos expression: implications for its use as a chemopreventive agent.

Journal: Cancer prevention research (Philadelphia, Pa.)20100701

Title: Mitochondrial dynamics and its responds to proteasome defection during Picea wilsonii pollen tube development.

Journal: Cell biochemistry and function20100701

Title: [Protected effects of MG-132 on apoptosis induced by deltamethrin in rat's hippocampus].

Journal: Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases20100701

Title: Calcium-sensing receptor biosynthesis includes a cotranslational conformational checkpoint and endoplasmic reticulum retention.

Journal: The Journal of biological chemistry20100625

Title: Oxidative stress enhances toll-like receptor 3 response to double-stranded RNA in airway epithelial cells.

Journal: American journal of respiratory cell and molecular biology20100601

Title: Breast cancer cell growth inhibition by phenethyl isothiocyanate is associated with down-regulation of oestrogen receptor-alpha36.

Journal: Journal of cellular and molecular medicine20100601

Title: MG132, a proteasome inhibitor decreased the growth of Calu-6 lung cancer cells via apoptosis and GSH depletion.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20100601

Title: Celastrol can inhibit proteasome activity and upregulate the expression of heat shock protein genes, hsp30 and hsp70, in Xenopus laevis A6 cells.

Journal: Comparative biochemistry and physiology. Part A, Molecular & integrative physiology20100601

Title: EP1 prostanoid receptor coupling to G i/o up-regulates the expression of hypoxia-inducible factor-1 alpha through activation of a phosphoinositide-3 kinase signaling pathway.

Journal: Molecular pharmacology20100601

Title: Treatment with p38 inhibitor partially prevents Calu-6 lung cancer cell death by a proteasome inhibitor, MG132.

Journal: Cancer genetics and cytogenetics20100601

Title: Functional roles of PC-PLC and Cdc20 in the cell cycle, proliferation, and apoptosis.

Journal: Cell biochemistry and function20100601

Title: Clioquinol independently targets NF-kappaB and lysosome pathways in human cancer cells.

Journal: Anticancer research20100601

Title: Attenuation of MG132-induced HeLa cell death by N-acetyl cysteine via reducing reactive oxygen species and preventing glutathione depletion.

Journal: Anticancer research20100601

Title: Hypopigmentary action of dihydropyranocoumarin D2, a decursin derivative, as a MITF-degrading agent.

Journal: Journal of natural products20100528

Title: Increased protein hydrophobicity in response to aging and Alzheimer disease.

Journal: Free radical biology & medicine20100515

Title: Proteasome inhibition induces hsp30 and hsp70 gene expression as well as the acquisition of thermotolerance in Xenopus laevis A6 cells.

Journal: Cell stress & chaperones20100501

Title: Zinc mesoporphyrin induces rapid proteasomal degradation of hepatitis C nonstructural 5A protein in human hepatoma cells.

Journal: Gastroenterology20100501

Title: Mechanical stretch enhances NF-kappaB-dependent gene expression and poly(ADP-ribose) synthesis in synovial cells.

Journal: Journal of biochemistry20100501

Title: Cdc20 proteolysis requires p38 MAPK signaling and Cdh1-independent APC/C ubiquitination during spindle assembly checkpoint activation by cadmium.

Journal: Journal of cellular physiology20100501

Title: Proliferative suppression by CDK4/6 inhibition: complex function of the retinoblastoma pathway in liver tissue and hepatoma cells.

Journal: Gastroenterology20100501

Title: MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes.

Journal: Arthritis and rheumatism20100501

Title: Novel exon nucleotide substitution at the splice junction causes a neonatal Marfan syndrome.

Journal: Clinical genetics20100501

Title: A novel sphingosine kinase inhibitor induces autophagy in tumor cells.

Journal: The Journal of pharmacology and experimental therapeutics20100501

Title: Diallyl disulfide and diallyl trisulfide protect endothelial nitric oxide synthase against damage by oxidized low-density lipoprotein.

Journal: Molecular nutrition & food research20100501

Title: Prolonged endoplasmic reticulum stress promotes mislocalization of immunoglobulins to the cytoplasm.

Journal: Molecular immunology20100501

Title: Lipopolysaccharide induced connective tissue growth factor gene expression in human bronchial epithelial cells.

Journal: Respirology (Carlton, Vic.)20100501

Title: Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling.

Journal: The Biochemical journal20100414

Title: Transcription factor Nrf1 mediates the proteasome recovery pathway after proteasome inhibition in mammalian cells.

Journal: Molecular cell20100409

Title: TNF-NF-kappaB signaling mediates excessive somnolence in hemiparkinsonian rats.

Journal: Behavioural brain research20100402

Title: AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes.

Journal: Circulation research20100402

Title: Proteasome inhibitor MG132 inhibits angiogenesis in pancreatic cancer by blocking NF-kappaB activity.

Journal: Digestive diseases and sciences20100401

Title: Proteasome inhibitor-induced apoptosis in acute myeloid leukemia: a correlation with the proteasome status.

Journal: Leukemia research20100401

Title: Role of the ubiquitin-proteasome pathway in downregulation of the gap-junction protein Connexin43 by TNF-{alpha} in human corneal fibroblasts.

Journal: Investigative ophthalmology & visual science20100401

Title: Defective TPA signalling compromises HaCat cells as a human in vitro skin carcinogenesis model.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20100401

Title: Evodiamine-induced human melanoma A375-S2 cell death was mediated by PI3K/Akt/caspase and Fas-L/NF-kappaB signaling pathways and augmented by ubiquitin-proteasome inhibition.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20100401

Title: A system-based comparison of gene expression reveals alterations in oxidative stress, disruption of ubiquitin-proteasome system and altered cell cycle regulation after exposure to cadmium and methylmercury in mouse embryonic fibroblast.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20100401

Title: alphaB-crystallin is mutant B-RAF regulated and contributes to cyclin D1 turnover in melanocytic cells.

Journal: Pigment cell & melanoma research20100401

Title: Decreased replication of human respiratory syncytial virus treated with the proteasome inhibitor MG-132.

Journal: Virus research20100401

Title: Parkin regulates metal transport via proteasomal degradation of the 1B isoforms of divalent metal transporter 1.

Journal: Journal of neurochemistry20100401

Title: (-)-Epigallocatechin-3-gallate downregulates Pg-P and BCRP in a tamoxifen resistant MCF-7 cell line.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20100401

Title: The effects of N-acetyl cysteine on the MG132 proteasome inhibitor-treated lung cancer cells in relation to cell growth, reactive oxygen species and glutathione.

Journal: International journal of molecular medicine20100401

Title: N-terminal residues regulate proteasomal degradation of AANAT.

Journal: Journal of pineal research20100401

Title: Novel combination of celecoxib and proteasome inhibitor MG132 provides synergistic antiproliferative and proapoptotic effects in human liver tumor cells.

Journal: Cell cycle (Georgetown, Tex.)20100401

Title: Sulindac metabolites induce proteosomal and lysosomal degradation of the epidermal growth factor receptor.

Journal: Cancer prevention research (Philadelphia, Pa.)20100401

Title: MG132, a proteasome inhibitor, attenuates pressure-overload-induced cardiac hypertrophy in rats by modulation of mitogen-activated protein kinase signals.

Journal: Acta biochimica et biophysica Sinica20100401

Title: [Effect of proteasome inhibitor MG-132 on L1210 cell apoptosis and its mechanism].

Journal: Zhongguo shi yan xue ye xue za zhi20100401

Title: Motexafin gadolinium enhances p53-Mdm2 interactions, reducing p53 and downstream targets in lymphoma cell lines.

Journal: Anticancer research20100401

Title: Imidazole inhibits B16 melanoma cell migration via degradation of beta-catenin.

Journal: The Journal of pharmacy and pharmacology20100401

Title: Proteasome activity correlates with male BMI and contributes to the differentiation of adipocyte in hADSC.

Journal: Endocrine20100401

Title: The changes of reactive oxygen species and glutathione by MG132, a proteasome inhibitor affect As4.1 juxtaglomerular cell growth and death.

Journal: Chemico-biological interactions20100330

Title: [Effect of MG-132 upon the expression of intercellular adhesion molecule-1 in cerulein-induced acute pancreatitis in mice].

Journal: Zhonghua yi xue za zhi20100330

Title: Functional interaction of phosphatase and tensin homologue (PTEN) with the E3 ligase NEDD4-1 during neuronal response to zinc.

Journal: The Journal of biological chemistry20100326

Title: Formation of parkin aggregates and enhanced PINK1 accumulation during the pathogenesis of Parkinson's disease.

Journal: Biochemical and biophysical research communications20100319

Title: Enhanced vulnerability of PARK6 patient skin fibroblasts to apoptosis induced by proteasomal stress.

Journal: Neuroscience20100317

Title: Mutational analysis of threonine 402 adjacent to the GXXXG dimerization motif in transmembrane segment 1 of ABCG2.

Journal: Biochemistry20100316

Title: Novel findings on endoribonuclease activity of proteasomes.

Journal: Cell cycle (Georgetown, Tex.)20100315

Title: In vitro and in vivo interaction of AtRma2 E3 ubiquitin ligase and auxin binding protein 1.

Journal: Biochemical and biophysical research communications20100312

Title: Combination therapy for hepatitis C virus with heat-shock protein 90 inhibitor 17-AAG and proteasome inhibitor MG132.

Journal: Antiviral chemistry & chemotherapy20100309

Title: Capsaicin sensitizes malignant glioma cells to TRAIL-mediated apoptosis via DR5 upregulation and survivin downregulation.

Journal: Carcinogenesis20100301

Title: Gap junctions sensitize cancer cells to proteasome inhibitor MG132-induced apoptosis.

Journal: Cancer science20100301

Title: Antidepressants increase β-arrestin 2 ubiquitinylation and degradation by the proteasomal pathway in C6 rat glioma cells.

Journal: The Journal of pharmacology and experimental therapeutics20100301

Title: Proteasomal inhibition upregulates the endogenous MAPK deactivator MKP-1 in human airway smooth muscle: mechanism of action and effect on cytokine secretion.

Journal: Biochimica et biophysica acta20100301

Title: Bone morphogenetic protein-7 inhibits proximal tubular epithelial cell Smad3 signaling via increased SnoN expression.

Journal: The American journal of pathology20100301

Title: Proteasome inhibitor MG132 suppresses number and function of endothelial progenitor cells: involvement of nitric oxide synthase inhibition.

Journal: International journal of molecular medicine20100301

Title: The 26S proteasome function and Hsp90 activity involved in the regulation of HsfA2 expression in response to oxidative stress.

Journal: Plant & cell physiology20100301

Title: MG132, a proteasome inhibitor, induced death of calf pulmonary artery endothelial cells via caspase-dependent apoptosis and GSH depletion.

Journal: Anticancer research20100301

Title: The pharmacological NFkappaB inhibitors BAY117082 and MG132 induce cell arrest and apoptosis in leukemia cells through ROS-mitochondria pathway activation.

Journal: Cancer letters20100227

Title: Studies of the synthesis of all stereoisomers of MG-132 proteasome inhibitors in the tumor targeting approach.

Journal: Journal of medicinal chemistry20100225

Title: The influence of proteasome inhibitor MG132, external radiation, and unlabeled antibody on the tumor uptake and biodistribution of (188)re-labeled anti-E6 C1P5 antibody in cervical cancer in mice.

Journal: Cancer20100215

Title: ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.

Journal: The Journal of biological chemistry20100212

Title: A role for the ubiquitin-proteasome system in activity-dependent presynaptic silencing.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20100203

Title: The effect of the time interval between injection and parthenogenetic activation on the spindle formation and the in vitro developmental potential of somatic cell nuclear-transferred rat oocytes.

Journal: Zygote (Cambridge, England)20100201

Title: Differential modulation of BRCA1 and BARD1 nuclear localisation and foci assembly by DNA damage.

Journal: Cellular signalling20100201

Title: Post-fusion treatment with MG132 increases transcription factor expression in somatic cell nuclear transfer embryos in pigs.

Journal: Molecular reproduction and development20100201

Title: The effects of MAPK inhibitors on a proteasome inhibitor, MG132-induced HeLa cell death in relation to reactive oxygen species and glutathione.

Journal: Toxicology letters20100201

Title: Cholera toxin-sensitive GTP-binding protein-coupled activation of augmenter of liver regeneration (ALR) receptor and its function in rat kupffer cells.

Journal: Journal of cellular physiology20100201

Title: Preventive effect of a proteasome inhibitor on the formation of accelerated atherosclerosis in rabbits with uremia.

Journal: Journal of cardiovascular pharmacology20100201

Title: Macroautophagy and ERK phosphorylation counteract the antiproliferative effect of proteasome inhibitor in gastric cancer cells.

Journal: Autophagy20100201

Title: ER stress negatively regulates AKT/TSC/mTOR pathway to enhance autophagy.

Journal: Autophagy20100201

Title: [Tumor stem cells and their impact on the concept of cancer treatment].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20100201

Title: Degradation of TDP-43 and its pathogenic form by autophagy and the ubiquitin-proteasome system.

Journal: Neuroscience letters20100118

Title: Multiple cardiac proteasome subtypes differ in their susceptibility to proteasome inhibitors.

Journal: Cardiovascular research20100115

Title: Ionizing radiation induces cellular senescence of articular chondrocytes via negative regulation of SIRT1 by p38 kinase.

Journal: The Journal of biological chemistry20100108

Title: Histone deacetylase inhibitors induce thyroid cancer-specific apoptosis through proteasome-dependent inhibition of TRAIL degradation.

Journal: Oncogene20100107

Title: Proteasome inhibition suppresses DNA-dependent protein kinase activation caused by camptothecin.

Journal: DNA repair20100102

Title: TLR3 in human eosinophils: functional effects and decreased expression during allergic rhinitis.

Journal: International archives of allergy and immunology20100101

Title: MG-132 inhibits carcinoid growth and alters the neuroendocrine phenotype.

Journal: The Journal of surgical research20100101

Title: The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway.

Journal: Experimental cell research20100101

Title: Stress-induced ER to Golgi translocation of ceramide synthase 1 is dependent on proteasomal processing.

Journal: Experimental cell research20100101

Title: Topotecan triggers apoptosis in p53-deficient cells by forcing degradation of XIAP and survivin thereby activating caspase-3-mediated Bid cleavage.

Journal: The Journal of pharmacology and experimental therapeutics20100101

Title: Mutations in NOTCH3 cause the formation and retention of aggregates in the endoplasmic reticulum, leading to impaired cell proliferation.

Journal: Human molecular genetics20100101

Title: Activation of PERK kinase in neural cells by proteasome inhibitor treatment.

Journal: Journal of neurochemistry20100101

Title: Prevention of intracellular degradation of I2020T mutant LRRK2 restores its protectivity against apoptosis.

Journal: Biochemical and biophysical research communications20100101

Title: Effect of overexpression of Arabidopsis damaged DNA-binding protein 1A on de-etiolated 1.

Journal: Planta20100101

Title: Pigment epithelium-derived factor inhibits lysosomal degradation of Bcl-xL and apoptosis in HepG2 cells.

Journal: The American journal of pathology20100101

Title: Uncoupling of the spindle-checkpoint and chromosome-congression functions of BubR1.

Journal: Journal of cell science20100101

Title: Interferon-alpha2b induces p21cip1/waf1 degradation and cell proliferation in HeLa cells.

Journal: Cell cycle (Georgetown, Tex.)20100101

Title: Tumor necrosis factor-a augments lipopolysaccharide-induced suppressor of cytokine signalling 3 (SOCS-3) protein expression by preventing the degradation.

Journal: Immunology20100101

Title: The inhibitory mechanisms of the tyrosine kinase inhibitors herbimycin a, genistein, and tyrphostin B48 with regard to the function of the aryl hydrocarbon receptor in Caco-2 cells.

Journal: Bioscience, biotechnology, and biochemistry20100101

Title: Processing of autophagic protein LC3 by the 20S proteasome.

Journal: Autophagy20100101

Title: Neuroprotective effects of the drug GVT (monosodium luminol) are mediated by the stabilization of Nrf2 in astrocytes.

Journal: Neurochemistry international20100101

Title: The attenuation of MG132, a proteasome inhibitor, induced A549 lung cancer cell death by p38 inhibitor in ROS-independent manner.

Journal: Oncology research20100101

Title: Selective estrogen receptor down-regulator and selective estrogen receptor modulators differentially regulate lactotroph proliferation.

Journal: PloS one20100101

Title: Angiotensin I-converting enzyme Gln1069Arg mutation impairs trafficking to the cell surface resulting in selective denaturation of the C-domain.

Journal: PloS one20100101

Title: Lamin A rod domain mutants target heterochromatin protein 1alpha and beta for proteasomal degradation by activation of F-box protein, FBXW10.

Journal: PloS one20100101

Title: p62/sequestosome 1 as a regulator of proteasome inhibitor-induced autophagy in human retinal pigment epithelial cells.

Journal: Molecular vision20100101

Title: Amino acid deprivation decreases intracellular levels of reactive oxygen species in hepatic stellate cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20100101

Title: Investigation of the eIF2alpha phosphorylation mechanism in response to proteasome inhibition in melanoma and breast cancer cells.

Journal: Molekuliarnaia biologiia20100101

Title: Involvement of BMPs/Smad signaling pathway in mechanical response in osteoblasts.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20100101

Title: Fas/CD95 down-regulation in lymphoma cells through acquired alkyllysophospholipid resistance: partial role of associated sphingomyelin deficiency.

Journal: The Biochemical journal20091214

Title: Covalent complexes of proteasome model with peptide aldehyde inhibitors MG132 and MG101: docking and molecular dynamics study.

Journal: Journal of molecular modeling20091201

Title: Proteasome inhibition suppresses Schwann cell dedifferentiation in vitro and in vivo.

Journal: Glia20091201

Title: Lysosome-dependent degradation of Notch3.

Journal: The international journal of biochemistry & cell biology20091201

Title: Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbfbeta in osteosarcoma cells.

Journal: Journal of cellular physiology20091201

Title: Accumulation of phosphorylated tyrosine hydroxylase into insoluble protein aggregates by inhibition of an ubiquitin-proteasome system in PC12D cells.

Journal: Journal of neural transmission (Vienna, Austria : 1996)20091201

Title: Human-specific induction of glutathione peroxidase-3 by proteasome inhibition in cardiovascular cells.

Journal: Free radical biology & medicine20091201

Title: Zn2+ mediates ischemia-induced impairment of the ubiquitin-proteasome system in the rat hippocampus.

Journal: Journal of neurochemistry20091201

Title: NRF2 cysteine residues are critical for oxidant/electrophile-sensing, Kelch-like ECH-associated protein-1-dependent ubiquitination-proteasomal degradation, and transcription activation.

Journal: Molecular pharmacology20091201

Title: Neuregulin-1 attenuated doxorubicin-induced decrease in cardiac troponins.

Journal: American journal of physiology. Heart and circulatory physiology20091201

Title: Disruption of N-linked glycosylation enhances ubiquitin-mediated proteasomal degradation of the human ATP-binding cassette transporter ABCG2.

Journal: The FEBS journal20091201

Title: Effects of inhibiting the proteasomal degradation of estrogen receptor alpha on estrogen receptor alpha activation under hypoxic conditions.

Journal: Biological & pharmaceutical bulletin20091201

Title: Protein kinase C-delta mediates down-regulation of heterogeneous nuclear ribonucleoprotein K protein: involvement in apoptosis induction.

Journal: Experimental cell research20091115

Title: The small heat shock protein HSP25 protects astrocytes against stress induced by proteasomal inhibition.

Journal: Glia20091101

Title: Proteasome inhibition modulates kinase activation in neural cells: relevance to ubiquitination, ribosomes, and survival.

Journal: Journal of neuroscience research20091101

Title: Skp2 enhances polyubiquitination and degradation of TIS21/BTG2/PC3, tumor suppressor protein, at the downstream of FoxM1.

Journal: Experimental cell research20091101

Title: Capillary electrophoresis for screening of 20S proteasome inhibitors.

Journal: Analytical biochemistry20091101

Title: Inhibition of the JNK signalling pathway enhances proteasome inhibitor-induced apoptosis of kidney cancer cells by suppression of BAG3 expression.

Journal: British journal of pharmacology20091101

Title: BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution.

Journal: Journal of neurochemistry20091101

Title: TDP-43 is recruited to stress granules in conditions of oxidative insult.

Journal: Journal of neurochemistry20091101

Title: Cdh1 controls the stability of TACC3.

Journal: Cell cycle (Georgetown, Tex.)20091101

Title: Downregulation of DeltaNp63alpha in keratinocytes by p14ARF-mediated SUMO-conjugation and degradation.

Journal: Cell cycle (Georgetown, Tex.)20091101

Title: Pivotal roles of snail inhibition and RKIP induction by the proteasome inhibitor NPI-0052 in tumor cell chemoimmunosensitization.

Journal: Cancer research20091101

Title: Proteasome inhibitors induce apoptosis in human lung cancer cells through a positive feedback mechanism and the subsequent Mcl-1 protein cleavage.

Journal: Oncogene20091029

Title: Capsaicin-induced apoptosis is regulated by endoplasmic reticulum stress- and calpain-mediated mitochondrial cell death pathways.

Journal: Toxicology20091029

Title: The water channel aquaporin-1 partitions into exosomes during reticulocyte maturation: implication for the regulation of cell volume.

Journal: Blood20091029

Title: Proteasome-dependent processing of topoisomerase I-DNA adducts into DNA double strand breaks at arrested replication forks.

Journal: The Journal of biological chemistry20091009

Title: Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1.

Journal: The Journal of biological chemistry20091009

Title: Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents.

Journal: Cancer chemotherapy and pharmacology20091001

Title: Proteomics analysis of nucleolar SUMO-1 target proteins upon proteasome inhibition.

Journal: Molecular & cellular proteomics : MCP20091001

Title: Genome-wide comparative analysis of type-A Arabidopsis response regulator genes by overexpression studies reveals their diverse roles and regulatory mechanisms in cytokinin signaling.

Journal: Cell research20091001

Title: The DOUBLETIME protein kinase regulates phosphorylation of the Drosophila PDP1epsilon.

Journal: Journal of neurochemistry20091001

Title: Regulation of stathmin phosphorylation in mouse liver progenitor-29 cells during proteasome inhibition.

Journal: Proteomics20091001

Title: Aurora-C: the youngest of 'the three (Aurora kinase) tenors' of mitotic symphony.

Journal: Cell cycle (Georgetown, Tex.)20091001

Title: Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6.

Journal: Proceedings of the National Academy of Sciences of the United States of America20090929

Title: Insig-mediated, sterol-accelerated degradation of the membrane domain of hamster 3-hydroxy-3-methylglutaryl-coenzyme A reductase in insect cells.

Journal: The Journal of biological chemistry20090925

Title: Ipl1/Aurora B kinase coordinates synaptonemal complex disassembly with cell cycle progression and crossover formation in budding yeast meiosis.

Journal: Genes & development20090915

Title: Repression of protein translation and mTOR signaling by proteasome inhibitor in colon cancer cells.

Journal: Biochemical and biophysical research communications20090904

Title: Crosstalk between Hsp70 molecular chaperone, lysosomes and proteasomes in autophagy-mediated proteolysis in human retinal pigment epithelial cells.

Journal: Journal of cellular and molecular medicine20090901

Title: Enforced expression of PPP1R13L increases tumorigenesis and invasion through p53-dependent and p53-independent mechanisms.

Journal: Molecular carcinogenesis20090901

Title: alpha-Synuclein promotes the recruitment of tau to protein inclusions in oligodendroglial cells: effects of oxidative and proteolytic stress.

Journal: Journal of molecular neuroscience : MN20090901

Title: Hepatic CYP3A suppression by high concentrations of proteasomal inhibitors: a consequence of endoplasmic reticulum (ER) stress induction, activation of RNA-dependent protein kinase-like ER-bound eukaryotic initiation factor 2alpha (eIF2alpha)-kinase (PERK) and general control nonderepressible-2 eIF2alpha kinase (GCN2), and global translational shutoff.

Journal: Molecular pharmacology20090901

Title: Autophagy-mediated insulin receptor down-regulation contributes to endoplasmic reticulum stress-induced insulin resistance.

Journal: Molecular pharmacology20090901

Title: Follicular thyroid cancer cell growth inhibition by proteosome inhibitor MG132.

Journal: The Journal of surgical research20090901

Title: Tyrosine nitration of PA700 activates the 26S proteasome to induce endothelial dysfunction in mice with angiotensin II-induced hypertension.

Journal: Hypertension (Dallas, Tex. : 1979)20090901

Title: Evaluation of in vitro cultured rat oocytes, from different strains, by spindle morphology and maturation-promoting-factor activity combined with nuclear-transfer experiments.

Journal: Cloning and stem cells20090901

Title: Arachidonic acid-induced apoptosis of human neuroblastoma SK-N-SH cells is mediated through mitochondrial alteration elicited by ROS and Ca(2+)-evoked activation of p38alpha MAPK and JNK1.

Journal: Toxicology20090821

Title: Endoplasmic reticulum-associated degradation (ERAD) and autophagy cooperate to degrade polymerogenic mutant serpins.

Journal: The Journal of biological chemistry20090821

Title: A tetrahedral transition state at the active sites of the 20S proteasome is coupled to opening of the alpha-ring channel.

Journal: Structure (London, England : 1993)20090812

Title: Proteasome inhibitors impair RANKL-induced NF-kappaB activity in osteoclast-like cells via disruption of p62, TRAF6, CYLD, and IkappaBalpha signaling cascades.

Journal: Journal of cellular physiology20090801

Title: Potent anti-inflammatory effects of low-dose proteasome inhibition in the vascular system.

Journal: Journal of molecular medicine (Berlin, Germany)20090801

Title: Ectodomain shedding and generation of two carboxy-terminal fragments of human complement receptor 2/CD21.

Journal: Molecular immunology20090801

Title: Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation.

Journal: Nature cell biology20090801

Title: BAX/BAK-independent mitoptosis during cell death induced by proteasome inhibition?

Journal: Molecular cancer research : MCR20090801

Title: Nucleus accumbens neurons exhibit synaptic scaling that is occluded by repeated dopamine pre-exposure.

Journal: The European journal of neuroscience20090801

Title: Cytosolic prion protein induces apoptosis in human neuronal cell SH-SY5Y via mitochondrial disruption pathway.

Journal: BMB reports20090731

Title: Proteasome inhibitors block HIV-1 replication by affecting both cellular and viral targets.

Journal: Biochemical and biophysical research communications20090717

Title: Nrf2-dependent upregulation of antioxidative enzymes: a novel pathway for proteasome inhibitor-mediated cardioprotection.

Journal: Cardiovascular research20090715

Title: Ubiquitination of HEXIM1 by HDM2.

Journal: Cell cycle (Georgetown, Tex.)20090715

Title: Determining time of death: temperature-dependent postmortem changes in calcineurin A, MARCKS, CaMKII, and protein phosphatase 2A in mouse.

Journal: International journal of legal medicine20090701

Title: Diclofenac enhances proinflammatory cytokine-induced nitric oxide production through NF-kappaB signaling in cultured astrocytes.

Journal: Toxicology and applied pharmacology20090701

Title: Stimulation of Akt poly-ubiquitination and proteasomal degradation in P388D1 cells by 7-ketocholesterol and 25-hydroxycholesterol.

Journal: Archives of biochemistry and biophysics20090701

Title: The effect of MG132, a proteasome inhibitor on HeLa cells in relation to cell growth, reactive oxygen species and GSH.

Journal: Oncology reports20090701

Title: Proteasome inhibitor MG-132 mediated expression of p27Kip1 via S-phase kinase protein 2 degradation induces cell cycle coupled apoptosis in primary effusion lymphoma cells.

Journal: Leukemia & lymphoma20090701

Title: Inhibition of autophagy induced by proteasome inhibition increases cell death in human SHG-44 glioma cells.

Journal: Acta pharmacologica Sinica20090701

Title: TGF-beta induces degradation of TAL1/SCL by the ubiquitin-proteasome pathway through AKT-mediated phosphorylation.

Journal: Blood20090625

Title: Zinc protoporphyrin inhibition of lipopolysaccharide-, lipoteichoic acid-, and peptidoglycan-induced nitric oxide production through stimulating iNOS protein ubiquitination.

Journal: Toxicology and applied pharmacology20090615

Title: Synthesis and biological evaluation of boron peptide analogues of Belactosin C as proteasome inhibitors.

Journal: Bioorganic & medicinal chemistry letters20090615

Title: Proteasome inhibitor differentially regulates expression of the major immediate early genes of human cytomegalovirus in human central nervous system-derived cell lines.

Journal: Virus research20090601

Title: Novel cytostatic activity of the trypanocidal drug Benznidazole.

Journal: International immunopharmacology20090601

Title: Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction.

Journal: American journal of physiology. Lung cellular and molecular physiology20090601

Title: The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C-Cdh1.

Journal: Nature cell biology20090601

Title: Cellular calcium deficiency plays a role in neuronal death caused by proteasome inhibitors.

Journal: Journal of neurochemistry20090601

Title: Long-term suppression of tyrosinase by terrein via tyrosinase degradation and its decreased expression.

Journal: Experimental dermatology20090601

Title: [Effect of proteasome inhibitors MG-132 at different doses on cultured K562 cell apoptosis].

Journal: Zhongguo shi yan xue ye xue za zhi20090601

Title: Comprehensive proteomic and transcriptomic analysis reveals early induction of a protective anti-oxidative stress response by low-dose proteasome inhibition.

Journal: Proteomics20090601

Title: Thioredoxin-related Protein 32 is an arsenite-regulated Thiol Reductase of the proteasome 19 S particle.

Journal: The Journal of biological chemistry20090529

Title: Expression of Epstein-Barr virus BZLF1 immediate-early protein induces p53 degradation independent of MDM2, leading to repression of p53-mediated transcription.

Journal: Virology20090525

Title: A new class of quinoline-based DNA hypomethylating agents reactivates tumor suppressor genes by blocking DNA methyltransferase 1 activity and inducing its degradation.

Journal: Cancer research20090515

Title: Method of oocyte activation affects cloning efficiency in pigs.

Journal: Molecular reproduction and development20090501

Title: Clusterin is a short half-life, poly-ubiquitinated protein, which controls the fate of prostate cancer cells.

Journal: Journal of cellular physiology20090501

Title: Participation of the human sperm proteasome in the capacitation process and its regulation by protein kinase A and tyrosine kinase.

Journal: Biology of reproduction20090501

Title: SCA8 repeat expansion: large CTA/CTG repeat alleles in neurological disorders and functional implications.

Journal: Human genetics20090501

Title: Investigation of a role for lysine residues in non-structural proteins 2 and 2/3 of the hepatitis C virus for their degradation and virus assembly.

Journal: The Journal of general virology20090501

Title: Codanin-1, the protein encoded by the gene mutated in congenital dyserythropoietic anemia type I (CDAN1), is cell cycle-regulated.

Journal: Haematologica20090501

Title: Transcriptional and posttranslational regulation of clusterin by the two main cellular proteolytic pathways.

Journal: Free radical biology & medicine20090501

Title: Talin phosphorylation by Cdk5 regulates Smurf1-mediated talin head ubiquitylation and cell migration.

Journal: Nature cell biology20090501

Title: Rapid proteasomal degradation of transcription factor IIB in accordance with F9 cell differentiation.

Journal: Gene20090501

Title: Disruption of the ubiquitin proteasome system following axonal stretch injury accelerates progression to secondary axotomy.

Journal: Journal of neurotrauma20090501

Title: Dynamic behavior of Arabidopsis eIF4A-III, putative core protein of exon junction complex: fast relocation to nucleolus and splicing speckles under hypoxia.

Journal: The Plant cell20090501

Title: [Effect of the proteasome inhibitor MG-132 on hyperoxic lung injury and its mechanism in rats].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University20090501

Title: Mutation of a single residue renders human tetherin resistant to HIV-1 Vpu-mediated depletion.

Journal: PLoS pathogens20090501

Title: D-glucosamine down-regulates HIF-1alpha through inhibition of protein translation in DU145 prostate cancer cells.

Journal: Biochemical and biophysical research communications20090424

Title: Decreased protein synthesis of Hsp27 associated with cellular toxicity in a cell model of Machado-Joseph disease.

Journal: Neuroscience letters20090424

Title: The ubiquitin ligase E6-AP is induced and recruited to aggresomes in response to proteasome inhibition and may be involved in the ubiquitination of Hsp70-bound misfolded proteins.

Journal: The Journal of biological chemistry20090417

Title: BH3 mimetic ABT-737 and a proteasome inhibitor synergistically kill melanomas through Noxa-dependent apoptosis.

Journal: The Journal of investigative dermatology20090401

Title: Aldosterone inhibits insulin-induced glucose uptake by degradation of insulin receptor substrate (IRS) 1 and IRS2 via a reactive oxygen species-mediated pathway in 3T3-L1 adipocytes.

Journal: Endocrinology20090401

Title: Endoplasmic reticulum stress-mediated autophagy/apoptosis induced by capsaicin (8-methyl-N-vanillyl-6-nonenamide) and dihydrocapsaicin is regulated by the extent of c-Jun NH2-terminal kinase/extracellular signal-regulated kinase activation in WI38 lung epithelial fibroblast cells.

Journal: The Journal of pharmacology and experimental therapeutics20090401

Title: ARC is a critical cardiomyocyte survival switch in doxorubicin cardiotoxicity.

Journal: Journal of molecular medicine (Berlin, Germany)20090401

Title: Mechanisms targeting apolipoprotein B100 to proteasomal degradation: evidence that degradation is initiated by BiP binding at the N terminus and the formation of a p97 complex at the C terminus.

Journal: Arteriosclerosis, thrombosis, and vascular biology20090401

Title: Low molecular mass polypeptide-2 in human trophoblast: over-expression in hydatidiform moles and possible role in trophoblast cell invasion.

Journal: Placenta20090401

Title: The effect of proteasome inhibitor MG132 on experimental inflammatory bowel disease.

Journal: Clinical and experimental immunology20090401

Title: New cyclic peptide proteasome inhibitors.

Journal: Bioorganic & medicinal chemistry letters20090401

Title: Dopamine (DA) induced irreversible proteasome inhibition via DA derived quinones.

Journal: Free radical research20090401

Title: Regulation of Cdh1-APC function in axon growth by Cdh1 phosphorylation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20090401

Title: [Induction of apoptosis by proteasome inhibitor MG-132 in human erythroleukemia cell line K562].

Journal: Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics20090401

Title: The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition.

Journal: Blood20090326

Title: Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.

Journal: The Journal of biological chemistry20090320

Title: COP9 signalosome- and 26S proteasome-dependent regulation of SCFTIR1 accumulation in Arabidopsis.

Journal: The Journal of biological chemistry20090320

Title: Disulfide and thioether linked cytochrome c-oligoarginine conjugates in HeLa cells.

Journal: International journal of pharmaceutics20090318

Title: Identification of a polymorphism in the RING finger of human Bmi-1 that causes its degradation by the ubiquitin-proteasome system.

Journal: FEBS letters20090318

Title: Manganese (II) induces chemical hypoxia by inhibiting HIF-prolyl hydroxylase: implication in manganese-induced pulmonary inflammation.

Journal: Toxicology and applied pharmacology20090315

Title: Adrenaline in pro-oxidant conditions elicits intracellular survival pathways in isolated rat cardiomyocytes.

Journal: Toxicology20090304

Title: Proteasomal inhibition reduces parkin mRNA in PC12 and SH-SY5Y cells.

Journal: Parkinsonism & related disorders20090301

Title: Regulation of estrogen receptor alpha expression in human breast cancer cells by sulforaphane.

Journal: The Journal of nutritional biochemistry20090301

Title: Proteasome inhibition induces neurite outgrowth through posttranslational modification of TrkA receptor.

Journal: The international journal of biochemistry & cell biology20090301

Title: Proteasome inhibitor MG132 induces BAG3 expression through activation of heat shock factor 1.

Journal: Journal of cellular physiology20090301

Title: Aggresome-forming TTRAP mediates pro-apoptotic properties of Parkinson's disease-associated DJ-1 missense mutations.

Journal: Cell death and differentiation20090301

Title: HDAC2 deacetylates class II transactivator and suppresses its activity in macrophages and smooth muscle cells.

Journal: Journal of molecular and cellular cardiology20090301

Title: West Nile virus genome amplification requires the functional activities of the proteasome.

Journal: Virology20090301

Title: Stable protein, unstable plaque?

Journal: Journal of molecular and cellular cardiology20090301

Title: Protective effect against Parkinson's disease-related insults through the activation of XBP1.

Journal: Brain research20090227

Title: Degradation of transglutaminase 2 by calcium-mediated ubiquitination responding to high oxidative stress.

Journal: FEBS letters20090218

Title: Discovery of novel small molecule cell type-specific enhancers of NF-kappaB nuclear translocation.

Journal: Bioorganic & medicinal chemistry letters20090215

Title: Inhibition of eIF2alpha dephosphorylation maximizes bortezomib efficiency and eliminates quiescent multiple myeloma cells surviving proteasome inhibitor therapy.

Journal: Cancer research20090215

Title: Tosylcyclonovobiocic acids promote cleavage of the hsp90-associated cochaperone p23.

Journal: Biochemical and biophysical research communications20090206

Title: Inhibition of rat liver cathepsins B and L by the peptide aldehyde benzyloxycarbonyl-leucyl-leucyl-leucinal and its analogues.

Journal: Journal of enzyme inhibition and medicinal chemistry20090201

Title: Intracellular zinc increase inhibits p53(-/-) pancreatic adenocarcinoma cell growth by ROS/AIF-mediated apoptosis.

Journal: Biochimica et biophysica acta20090201

Title: Major SNP (Q141K) variant of human ABC transporter ABCG2 undergoes lysosomal and proteasomal degradations.

Journal: Pharmaceutical research20090201

Title: Akt-dependent NF-kappaB activation is required for bile acids to rescue colon cancer cells from stress-induced apoptosis.

Journal: Experimental cell research20090201

Title: Proteasome regulation of dynamic transcription factor occupancy on the GnRH-stimulated luteinizing hormone beta-subunit promoter.

Journal: Molecular endocrinology (Baltimore, Md.)20090201

Title: Dyclonine and alverine citrate enhance the cytotoxic effects of proteasome inhibitor MG132 on breast cancer cells.

Journal: International journal of molecular medicine20090201

Title: A histone deacetylase inhibitor LBH589 downregulates XIAP in mesothelioma cell lines which is likely responsible for increased apoptosis with TRAIL.

Journal: Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer20090201

Title: Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.

Journal: Innate immunity20090201

Title: Estrogen and hypoxia regulate estrogen receptor alpha in a synergistic manner.

Journal: Biochemical and biophysical research communications20090123

Title: Isolation of human proteasomes and putative proteasome-interacting proteins using a novel affinity chromatography method.

Journal: Experimental cell research20090115

Title: Minitags for small molecules: detecting targets of reactive small molecules in living plant tissues using 'click chemistry'.

Journal: The Plant journal : for cell and molecular biology20090101

Title: Soluble and insoluble nickel compounds exert a differential inhibitory effect on cell growth through IKKalpha-dependent cyclin D1 down-regulation.

Journal: Journal of cellular physiology20090101

Title: Phenethyl isothiocyanate induces cell cycle arrest and reduction of alpha- and beta-tubulin isotypes in human prostate cancer cells.

Journal: Cell biology international20090101

Title: Substrate selection by the proteasome during degradation of protein complexes.

Journal: Nature chemical biology20090101

Title: Protection against amyloid beta cytotoxicity by sulforaphane: role of the proteasome.

Journal: Archives of pharmacal research20090101

Title: The anti-apoptotic activity of BAG3 is restricted by caspases and the proteasome.

Journal: PloS one20090101

Title: Changes in proteasome structure and function caused by HAMLET in tumor cells.

Journal: PloS one20090101

Title: Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cells.

Journal: PloS one20090101

Title: GSK3beta is involved in JNK2-mediated beta-catenin inhibition.

Journal: PloS one20090101

Title: Targeting hypoxia in cancer cells by restoring homeodomain interacting protein-kinase 2 and p53 activity and suppressing HIF-1alpha.

Journal: PloS one20090101

Title: Novel mitochondrial substrates of omi indicate a new regulatory role in neurodegenerative disorders.

Journal: PloS one20090101

Title: Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration.

Journal: PloS one20090101

Title: Estradiol and progesterone-mediated regulation of P-gp in P-gp overexpressing cells (NCI-ADR-RES) and placental cells (JAR).

Journal: Molecular pharmaceutics20090101

Title: Notch versus the proteasome: what is the target of gamma-secretase inhibitor-I?

Journal: Breast cancer research : BCR20090101

Title: TRIM5alpha and TRIMCyp form apparent hexamers and their multimeric state is not affected by exposure to restriction-sensitive viruses or by treatment with pharmacological inhibitors.

Journal: Retrovirology20090101

Title: Mechanisms of c-myc degradation by nickel compounds and hypoxia.

Journal: PloS one20090101

Title: Dual regulation of TERT activity through transcription and splicing by DeltaNP63alpha.

Journal: Aging20090101

Title: Celecoxib-induced degradation of T-cell factors-1 and -4 in human colon cancer cells.

Journal: Biochemical and biophysical research communications20081226

Title: Quercetin sensitizes human hepatoma cells to TRAIL-induced apoptosis via Sp1-mediated DR5 up-regulation and proteasome-mediated c-FLIPS down-regulation.

Journal: Journal of cellular biochemistry20081215

Title: The ubiquitin-like modifier FAT10 interacts with HDAC6 and localizes to aggresomes under proteasome inhibition.

Journal: Journal of cell science20081215

Title: p53 is localized to a sub-nucleolar compartment after proteasomal inhibition in an energy-dependent manner.

Journal: Journal of cell science20081215

Title: Proteasome inhibitor-induced apoptosis is mediated by positive feedback amplification of PKCdelta proteolytic activation and mitochondrial translocation.

Journal: Journal of cellular and molecular medicine20081201

Title: TNF-alpha stimulates Akt by a distinct aPKC-dependent pathway in premalignant keratinocytes.

Journal: Experimental dermatology20081201

Title: The expression of tubulin polymerization promoting protein TPPP/p25alpha is developmentally regulated in cultured rat brain oligodendrocytes and affected by proteolytic stress.

Journal: Glia20081201

Title: Treatment with proteasome inhibitor MG132 during cloning improves survival and pronuclear number of reconstructed rat embryos.

Journal: Cloning and stem cells20081201

Title: A therapeutic dose of doxorubicin activates ubiquitin-proteasome system-mediated proteolysis by acting on both the ubiquitination apparatus and proteasome.

Journal: American journal of physiology. Heart and circulatory physiology20081201

Title: Inhibition of the ubiquitin-proteasome activity prevents glutamate transporter degradation and morphine tolerance.

Journal: Pain20081201

Title: The developmental potential of parthenogenetic and somatic cell nuclear-transferred rat oocytes in vitro.

Journal: Cloning and stem cells20081201

Title: MG-132 inhibits telomerase activity, induces apoptosis and G(1) arrest associated with upregulated p27kip1 expression and downregulated survivin expression in gastric carcinoma cells.

Journal: Cancer investigation20081201

Title: Binding of MG132 or deletion of the Thr active sites in HslV subunits increases the affinity of HslV protease for HslU ATPase and makes this interaction nucleotide-independent.

Journal: The Journal of biological chemistry20081128

Title: The Arabidopsis receptor-like kinase STRUBBELIG mediates inter-cell-layer signaling during floral development.

Journal: Developmental biology20081115

Title: MG-132 inhibits the TCDD-mediated induction of Cyp1a1 at the catalytic activity but not the mRNA or protein levels in Hepa 1c1c7 cells.

Journal: Toxicology letters20081110

Title: Inactivation of NF-kappaB by proteasome inhibition contributes to increased apoptosis induced by histone deacetylase inhibitors in human breast cancer cells.

Journal: Breast cancer research and treatment20081101

Title: Geminin is overexpressed in human pancreatic cancer and downregulated by the bioflavanoid apigenin in pancreatic cancer cell lines.

Journal: Molecular carcinogenesis20081101

Title: The ubiquitin-proteasome system is a key component of the SUMO-2/3 cycle.

Journal: Molecular & cellular proteomics : MCP20081101

Title: Involvement of p53 and Raf/MEK/ERK pathways in hematopoietic drug resistance.

Journal: Leukemia20081101

Title: MDM2 E3 ubiquitin ligase mediates UT-A1 urea transporter ubiquitination and degradation.

Journal: American journal of physiology. Renal physiology20081101

Title: Proteasome-dependent degradation of Chk1 kinase induced by the topoisomerase II inhibitor R16 contributes to its anticancer activity.

Journal: Cancer biology & therapy20081101

Title: Peroxynitrite augments fibroblast-mediated tissue remodeling via myofibroblast differentiation.

Journal: American journal of physiology. Lung cellular and molecular physiology20081101

Title: Interaction between cFLIP and Itch, a ubiquitin ligase, is obstructed in Trypanosoma cruzi-infected human cells.

Journal: Microbiology and immunology20081101

Title: Stress and IGF-I differentially control cell fate through mammalian target of rapamycin (mTOR) and retinoblastoma protein (pRB).

Journal: The Journal of biological chemistry20081017

Title: Compromised proteasome degradation elevates neuronal nitric oxide synthase levels and induces apoptotic cell death.

Journal: Archives of biochemistry and biophysics20081015

Title: Proteasome inhibition compromises direct retention of cytochrome P450 2C2 in the endoplasmic reticulum.

Journal: Experimental cell research20081015

Title: Von Hippel-Lindau-coupled and transcription-coupled nucleotide excision repair-dependent degradation of RNA polymerase II in response to trabectedin.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20081015

Title: In vivo investigations on anti-fibrotic potential of proteasome inhibition in lung and skin fibrosis.

Journal: American journal of respiratory cell and molecular biology20081001

Title: The AAA-ATPase p97 facilitates degradation of apolipoprotein B by the ubiquitin-proteasome pathway.

Journal: Journal of lipid research20081001

Title: Quercetin-induced ubiquitination and down-regulation of Her-2/neu.

Journal: Journal of cellular biochemistry20081001

Title: Mesenchymal stem cells therapy exerts neuroprotection in a progressive animal model of Parkinson's disease.

Journal: Journal of neurochemistry20081001

Title: NF-kappaB-dependency and consequent regulation of IL-8 in echinomycin-induced apoptosis of HT-29 colon cancer cells.

Journal: Cell biology international20081001

Title: Caspase-3 activation as a key factor for HBx-transformed cell death.

Journal: Cell proliferation20081001

Title: Quantitative analysis of global ubiquitination in HeLa cells by mass spectrometry.

Journal: Journal of proteome research20081001

Title: Troglitazone increases IL-1beta induced cyclooxygenase-2 and inducible nitric oxide synthase expression via enhanced phosphorylation of IkappaBalpha in vascular smooth muscle cells from Wistar-Kyoto rats and spontaneously hypertensive rats.

Journal: Biological & pharmaceutical bulletin20081001

Title: TNF alpha-induced down-regulation of estrogen receptor alpha in MCF-7 breast cancer cells.

Journal: Molecules and cells20080930

Title: Induction of autophagy by proteasome inhibitor is associated with proliferative arrest in colon cancer cells.

Journal: Biochemical and biophysical research communications20080919

Title: A robust ex vivo model for evaluation of induction of apoptosis by rhTRAIL in combination with proteasome inhibitor MG132 in human premalignant cervical explants.

Journal: International journal of cancer20080915

Title: Curcumin inhibits the proteasome activity in human colon cancer cells in vitro and in vivo.

Journal: Cancer research20080915

Title: Activation of Cdk2 stimulates proteasome-dependent truncation of tyrosine phosphatase SHP-1 in human proliferating intestinal epithelial cells.

Journal: The Journal of biological chemistry20080912

Title: Chemical and biological approaches synergize to ameliorate protein-folding diseases.

Journal: Cell20080905

Title: Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2.

Journal: American journal of respiratory cell and molecular biology20080901

Title: A p38-p65 transcription complex induced by endothelin-1 mediates signal transduction in cancer cells.

Journal: Biochimica et biophysica acta20080901

Title: Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition.

Journal: Cardiovascular research20080901

Title: Proteasome inhibition and stress compromise the heart in chemotherapy.

Journal: Cardiovascular research20080901

Title: Bortezomib induces apoptosis in esophageal squamous cell carcinoma cells through activation of the p38 mitogen-activated protein kinase pathway.

Journal: Molecular cancer therapeutics20080901

Title: Opa1-mediated cristae opening is Bax/Bak and BH3 dependent, required for apoptosis, and independent of Bak oligomerization.

Journal: Molecular cell20080822

Title: BACH1 is a specific repressor of HMOX1 that is inactivated by arsenite.

Journal: The Journal of biological chemistry20080815

Title: Antitumor activity of bis-indole derivatives.

Journal: Journal of medicinal chemistry20080814

Title: Cystic fibrosis transmembrane regulator missing the first four transmembrane segments increases wild type and DeltaF508 processing.

Journal: The Journal of biological chemistry20080808

Title: MG132 proteasome inhibitor modulates proinflammatory cytokines production and expression of their receptors in U937 cells: involvement of nuclear factor-kappaB and activator protein-1.

Journal: Immunology20080801

Title: Methionine sulfoxide reductase A protects dopaminergic cells from Parkinson's disease-related insults.

Journal: Free radical biology & medicine20080801

Title: Cadmium-induced activation of stress signaling pathways, disruption of ubiquitin-dependent protein degradation and apoptosis in primary rat Sertoli cell-gonocyte cocultures.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20080801

Title: Angiotensin II type 1 receptor signaling contributes to synaptophysin degradation and neuronal dysfunction in the diabetic retina.

Journal: Diabetes20080801

Title: Morphine induces ubiquitin-proteasome activity and glutamate transporter degradation.

Journal: The Journal of biological chemistry20080801

Title: Transient membrane recruitment of IRAK-1 in response to LPS and IL-1beta requires TNF R1.

Journal: American journal of physiology. Cell physiology20080801

Title: Pregnancy-upregulated nonubiquitous calmodulin kinase induces ligand-independent EGFR degradation.

Journal: American journal of physiology. Cell physiology20080801

Title: EF24, a novel curcumin analog, disrupts the microtubule cytoskeleton and inhibits HIF-1.

Journal: Cell cycle (Georgetown, Tex.)20080801

Title: Proteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IkappaBalpha.

Journal: Archives of biochemistry and biophysics20080715

Title: Laminin activates NF-kappaB in Schwann cells to enhance neurite outgrowth.

Journal: Neuroscience letters20080704

Title: C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors.

Journal: European journal of medicinal chemistry20080701

Title: Proteasome inhibition reduces avian reovirus replication and apoptosis induction in cultured cells.

Journal: Journal of virological methods20080701

Title: Adaptation to chronic MG132 reduces oxidative toxicity by a CuZnSOD-dependent mechanism.

Journal: Journal of neurochemistry20080701

Title: Jasmonate-induced nicotine formation in tobacco is mediated by tobacco COI1 and JAZ genes.

Journal: Plant & cell physiology20080701

Title: Activation of Nrf2 in defense against cadmium-induced oxidative stress.

Journal: Chemical research in toxicology20080701

Title: Inhibition of proteasome activity promotes the correct localization of disease-causing alpha-sarcoglycan mutants in HEK-293 cells constitutively expressing beta-, gamma-, and delta-sarcoglycan.

Journal: The American journal of pathology20080701

Title: Modulation of peroxisome proliferator-activated receptor gamma stability and transcriptional activity in adipocytes by resveratrol.

Journal: Metabolism: clinical and experimental20080701

Title: Phosphoinositide 3-kinase/AKT signaling can promote AIB1 stability independently of GSK3 phosphorylation.

Journal: Cancer research20080701

Title: Proteasome inhibitor MG-132 lowers gastric adenocarcinoma TMK1 cell proliferation via bone morphogenetic protein signaling.

Journal: Biochemical and biophysical research communications20080627

Title: Increased cytoplasmic levels of CIS, SOCS1, SOCS2, or SOCS3 are required for nuclear translocation.

Journal: FEBS letters20080625

Title: Proteasome inhibitors enhance TRAIL-induced apoptosis through the intronic regulation of DR5: involvement of NF-kappa B and reactive oxygen species-mediated p53 activation.

Journal: Journal of immunology (Baltimore, Md. : 1950)20080615

Title: Anti-inflammatory effects of a bioavailable compound, Artepillin C, in Brazilian propolis.

Journal: European journal of pharmacology20080610

Title: Involvement of hypoxia-inducing factor-1alpha-dependent plasminogen activator inhibitor-1 up-regulation in Cyr61/CCN1-induced gastric cancer cell invasion.

Journal: The Journal of biological chemistry20080606

Title: The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms.

Journal: Life sciences20080606

Title: Mechanisms of DJ-1 neuroprotection in a cellular model of Parkinson's disease.

Journal: Journal of neurochemistry20080601

Title: In vitro toxicity evaluation of diesel exhaust particles on human eosinophilic cell.

Journal: Toxicology in vitro : an international journal published in association with BIBRA20080601

Title: NAD(P)H quinone oxidoreductase 1 inhibits the proteasomal degradation of the tumour suppressor p33(ING1b).

Journal: EMBO reports20080601

Title: Bone morphogenetic protein signalling is required for the anti-mitogenic effect of the proteasome inhibitor MG-132 on colon cancer cells.

Journal: British journal of pharmacology20080601

Title: Fasudil-induced hypoxia-inducible factor-1alpha degradation disrupts a hypoxia-driven vascular endothelial growth factor autocrine mechanism in endothelial cells.

Journal: Molecular cancer therapeutics20080601

Title: Proteasome inhibitor ameliorates severe acute pancreatitis and associated lung injury of rats.

Journal: World journal of gastroenterology20080528

Title: RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage.

Journal: The Journal of biological chemistry20080516

Title: Caspase-dependent cleavage of BAG3 in proteasome inhibitors-induced apoptosis in thyroid cancer cells.

Journal: Biochemical and biophysical research communications20080509

Title: Regulation of bim in glucocorticoid-mediated osteoblast apoptosis.

Journal: Journal of cellular physiology20080501

Title: Degradation of caspase-activated DNase by the ubiquitin-proteasome system.

Journal: Biochimica et biophysica acta20080501

Title: Ubiquitin-mediated proteasomal degradation of non-synonymous SNP variants of human ABC transporter ABCG2.

Journal: The Biochemical journal20080501

Title: Mannosidase I inhibition rescues the human alpha-sarcoglycan R77C recurrent mutation.

Journal: Human molecular genetics20080501

Title: Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells.

Journal: Cancer science20080501

Title: CD28 ligation in the absence of TCR promotes RelA/NF-kappaB recruitment and trans-activation of the HIV-1 LTR.

Journal: European journal of immunology20080501

Title: Cytokinin inhibits the proteasome-mediated degradation of carbonylated proteins in Arabidopsis leaves.

Journal: Plant & cell physiology20080501

Title: Steroidogenic acute regulatory protein gene expression, steroid-hormone secretion and proliferative activity of adrenocortical cells in the presence of proteasome inhibitors: in vivo studies on the regenerating rat adrenal cortex.

Journal: International journal of molecular medicine20080501

Title: The HIV-1 Vif protein mediates degradation of Vpr and reduces Vpr-induced cell cycle arrest.

Journal: DNA and cell biology20080501

Title: Endogenous dopamine (DA) renders dopaminergic cells vulnerable to challenge of proteasome inhibitor MG132.

Journal: Free radical research20080501

Title: CK2 controls TRAIL and Fas sensitivity by regulating FLIP levels in endometrial carcinoma cells.

Journal: Oncogene20080417

Title: Flavonoids-induced accumulation of hypoxia-inducible factor (HIF)-1alpha/2alpha is mediated through chelation of iron.

Journal: Journal of cellular biochemistry20080415

Title: Involvement of mitogen-activated protein kinases and NFkappaB in LPS-induced CD40 expression on human monocytic cells.

Journal: Toxicology and applied pharmacology20080415

Title: Nickel compounds induce histone ubiquitination by inhibiting histone deubiquitinating enzyme activity.

Journal: Toxicology and applied pharmacology20080415

Title: Proteasome-dependent pharmacological rescue of cystic fibrosis transmembrane conductance regulator revealed by mutation of glycine 622.

Journal: The Journal of pharmacology and experimental therapeutics20080401

Title: Effects of proteasome inhibitor, MG132, on proteasome activity and oxidative status of rat liver.

Journal: Cell biochemistry and function20080401

Title: Proteasome inhibitor MG132 reverses multidrug resistance of gastric cancer through enhancing apoptosis and inhibiting P-gp.

Journal: Cancer biology & therapy20080401

Title: Proteasome inhibitor MG-132 modifies coxsackie and adenovirus receptor expression in colon cancer cell line lovo.

Journal: Cell cycle (Georgetown, Tex.)20080401

Title: CITED2 mediates the paradoxical responses of HIF-1alpha to proteasome inhibition.

Journal: Oncogene20080320

Title: Vinyl ester-based cyclic peptide proteasome inhibitors.

Journal: Bioorganic & medicinal chemistry letters20080315

Title: Coiled-coil domain containing 85B suppresses the beta-catenin activity in a p53-dependent manner.

Journal: Oncogene20080306

Title: Proteasome inhibitor MG132 blocks viral DNA replication and assembly of human cytomegalovirus.

Journal: FEBS letters20080305

Title: Prevention of deoxycholate-induced gastric apoptosis by aspirin: roles of NF-kappaB and PKC signaling.

Journal: The Journal of surgical research20080301

Title: The two isoforms of the Na+/Ca2+ exchanger, NCX1 and NCX3, constitute novel additional targets for the prosurvival action of Akt/protein kinase B pathway.

Journal: Molecular pharmacology20080301

Title: The role of sperm proteasomes during sperm aster formation and early zygote development: implications for fertilization failure in humans.

Journal: Human reproduction (Oxford, England)20080301

Title: A high-content chemical screen identifies ellipticine as a modulator of p53 nuclear localization.

Journal: Apoptosis : an international journal on programmed cell death20080301

Title: Decreased epithelial barrier function evoked by exposure to metabolic stress and nonpathogenic E. coli is enhanced by TNF-alpha.

Journal: American journal of physiology. Gastrointestinal and liver physiology20080301

Title: Inhibition of JAK1, 2/STAT3 signaling induces apoptosis, cell cycle arrest, and reduces tumor cell invasion in colorectal cancer cells.

Journal: Neoplasia (New York, N.Y.)20080301

Title: Zinc mesoporphyrin induces rapid and marked degradation of the transcription factor Bach1 and up-regulates HO-1.

Journal: Biochimica et biophysica acta20080301

Title: Secretory products from human adipocytes impair endothelial function via nuclear factor kappaB.

Journal: Atherosclerosis20080201

Title: The HMG-CoA reductase inhibitor rosuvastatin inhibits plasminogen activator inhibitor-1 expression and secretion in human adipocytes.

Journal: Atherosclerosis20080201

Title: Defective protein folding and intracellular retention of thyroglobulin-R19K mutant as a cause of human congenital goiter.

Journal: Molecular endocrinology (Baltimore, Md.)20080201

Title: XND1, a member of the NAC domain family in Arabidopsis thaliana, negatively regulates lignocellulose synthesis and programmed cell death in xylem.

Journal: The Plant journal : for cell and molecular biology20080201

Title: Proteasomal degradation of human release factor eRF3a regulates translation termination complex formation.

Journal: RNA (New York, N.Y.)20080201

Title: Suppression of cardiomyocyte hypertrophy by inhibition of the ubiquitin-proteasome system.

Journal: Hypertension (Dallas, Tex. : 1979)20080201

Title: Antioxidants block proteasome inhibitor function in endometrial carcinoma cells.

Journal: Anti-cancer drugs20080201

Title: Effects of protein phosphorylation on ubiquitination and stability of the translational inhibitor protein 4E-BP1.

Journal: Oncogene20080131

Title: Inefficient glycosylation leads to high steady-state levels of actively degrading cardiac triadin-1.

Journal: The Journal of biological chemistry20080125

Title: Characterization of a short isoform of human Tgs1 hypermethylase associating with small nucleolar ribonucleoprotein core proteins and produced by limited proteolytic processing.

Journal: The Journal of biological chemistry20080125

Title: Characterization of the cell membrane-associated products of the Neuregulin 4 gene.

Journal: Oncogene20080124

Title: Differential GATA factor stabilities: implications for chromatin occupancy by structurally similar transcription factors.

Journal: Biochemistry20080122

Title: Regulation of 3-phosphoinositide-dependent protein kinase-1 (PDK1) by Src involves tyrosine phosphorylation of PDK1 and Src homology 2 domain binding.

Journal: The Journal of biological chemistry20080118

Title: Effectors of rapid homeostatic responses of endoplasmic reticulum cholesterol and 3-hydroxy-3-methylglutaryl-CoA reductase.

Journal: The Journal of biological chemistry20080118

Title: The ubiquitin-mediated degradation of Jak1 modulates osteoclastogenesis by limiting interferon-beta-induced inhibitory signaling.

Journal: Blood20080115

Title: Tbx6, Thylacine1, and E47 synergistically activate bowline expression in Xenopus somitogenesis.

Journal: Developmental biology20080115

Title: Pyruvate dehydrogenase complex deficiency caused by ubiquitination and proteasome-mediated degradation of the E1 subunit.

Journal: The Journal of biological chemistry20080104

Title: Diminished feedback regulation of proteasome expression and resistance to proteasome inhibitors in breast cancer cells.

Journal: Breast cancer research and treatment20080101

Title: Tristetraprolin regulates TNF TNF-alpha mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways.

Journal: Molecular immunology20080101

Title: Identification of novel antiangiogenic anticancer activities of deguelin targeting hypoxia-inducible factor-1 alpha.

Journal: International journal of cancer20080101

Title: Delta 9-tetrahydrocannabinol inhibits cell cycle progression by downregulation of E2F1 in human glioblastoma multiforme cells.

Journal: Acta oncologica (Stockholm, Sweden)20080101

Title: Proteolytic activity of the 26S proteasome is required for the meiotic resumption, germinal vesicle breakdown, and cumulus expansion of porcine cumulus-oocyte complexes matured in vitro.

Journal: Biology of reproduction20080101

Title: Identification of N-(quinolin-8-yl)benzenesulfonamides as agents capable of down-regulating NFkappaB activity within two separate high-throughput screens of NFkappaB activation.

Journal: Bioorganic & medicinal chemistry letters20080101

Title: A novel class of intrinsic proteasome inhibitory gene transfer peptides.

Journal: Bioconjugate chemistry20080101

Title: Involvement of two distinct ubiquitin E3 ligase systems for p27 degradation in corneal endothelial cells.

Journal: Investigative ophthalmology & visual science20080101

Title: Down-regulation of brain-pancreas relative protein in diabetic rats and by high glucose in PC12 cells: prevention by calpain inhibitors.

Journal: Journal of pharmacological sciences20080101

Title: Expression of K6W-ubiquitin in lens epithelial cells leads to upregulation of a broad spectrum of molecular chaperones.

Journal: Molecular vision20080101

Title: The proteasome inhibitor MG132 induces nuclear translocation of erythroid transcription factor Nrf2 and cyclooxygenase-2 expression in human vascular endothelial cells.

Journal: Thrombosis research20080101

Title: Different effect of proteasome inhibition on vesicular stomatitis virus and poliovirus replication.

Journal: PloS one20080101

Title: Identification and characterization of two splicing variants of human Noxa.

Journal: Anticancer research20080101

Title: APOBEC3G-UBA2 fusion as a potential strategy for stable expression of APOBEC3G and inhibition of HIV-1 replication.

Journal: Retrovirology20080101

Title: Regulation of the Arabidopsis GSK3-like kinase BRASSINOSTEROID-INSENSITIVE 2 through proteasome-mediated protein degradation.

Journal: Molecular plant20080101

Title: The application and relevance of ex vivo culture systems for assessment of IBD treatment in murine models of colitis.

Journal: Pharmacological research20080101

Title: A single mutation at lysine 241 alters expression and trafficking of the D2 dopamine receptor.

Journal: Journal of receptor and signal transduction research20080101

Title: Local induction of heat shock protein 70 (Hsp70) by proteasome inhibition confers chondroprotection during surgically induced osteoarthritis in the rat knee.

Journal: Bio-medical materials and engineering20080101

Title: tabAnti-HER2 (erbB-2) oncogene effects of phenolic compounds directly isolated from commercial Extra-Virgin Olive Oil (EVOO).

Journal: BMC cancer20080101

Title: c-IAP1 cooperates with Myc by acting as a ubiquitin ligase for Mad1.

Journal: Molecular cell20071214

Title: Reduction of infectious bursal disease virus replication in cultured cells by proteasome inhibitors.

Journal: Virus genes20071201

Title: Trafficking of the bZIP transmembrane transcription factor CREB-H into alternate pathways of ERAD and stress-regulated intramembrane proteolysis.

Journal: Traffic (Copenhagen, Denmark)20071201

Title: PPARalpha agonists inhibit nitric oxide production by enhancing iNOS degradation in LPS-treated macrophages.

Journal: British journal of pharmacology20071201

Title: Absence of Bax switched MG132-induced apoptosis to non-apoptotic cell death that could be suppressed by transcriptional or translational inhibition.

Journal: Apoptosis : an international journal on programmed cell death20071201

Title: Curcumin, both histone deacetylase and p300/CBP-specific inhibitor, represses the activity of nuclear factor kappa B and Notch 1 in Raji cells.

Journal: Basic & clinical pharmacology & toxicology20071201

Title: A mutation in CHN-1/CHIP suppresses muscle degeneration in Caenorhabditis elegans.

Journal: Developmental biology20071201

Title: The complete removal of cohesin from chromosome arms depends on separase.

Journal: Journal of cell science20071201

Title: The protein degradation response of Saccharomyces cerevisiae to classical DNA-damaging agents.

Journal: Chemical research in toxicology20071201

Title: NKp30 ligation induces rapid activation of the canonical NF-kappaB pathway in NK cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20071201

Title: Viral control of the SUMO pathway: Gam1, a model system.

Journal: Biochemical Society transactions20071201

Title: [Protective effect of proteasome inhibitor MG-132 in rats with severe acute pancreatitis and lung injury].

Journal: Nan fang yi ke da xue xue bao = Journal of Southern Medical University20071201

Title: Hsp70B' regulation and function.

Journal: Cell stress & chaperones20071201

Title: Proteasomes control caspase-1 activation in anthrax lethal toxin-mediated cell killing.

Journal: The Journal of biological chemistry20071123

Title: Ubiquitin-conjugating enzyme Cdc34 mediates cadmium resistance in budding yeast through ubiquitination of the transcription factor Met4.

Journal: Biochemical and biophysical research communications20071123

Title: Tamoxifen accelerates proteasomal degradation of O6-methylguanine DNA methyltransferase in human cancer cells.

Journal: International journal of cancer20071115

Title: NSAIDs enhance proteasomic degradation of survivin, a mechanism of gastric epithelial cell injury and apoptosis.

Journal: Biochemical pharmacology20071115

Title: Aryl hydrocarbon receptor signaling in rainbow trout hepatocytes: role of hsp90 and the proteasome.

Journal: Comparative biochemistry and physiology. Toxicology & pharmacology : CBP20071101

Title: Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases.

Journal: American journal of physiology. Cell physiology20071101

Title: Identification of ubiquitin target proteins using cell-based arrays.

Journal: Journal of proteome research20071101

Title: Inhibition of paclitaxel-induced proteasome activation influences paclitaxel cytotoxicity in breast cancer cells in a sequence-dependent manner.

Journal: Cell cycle (Georgetown, Tex.)20071101

Title: Mutant and misfolded human growth hormone is rapidly degraded through the proteasomal degradation pathway in a cellular model for isolated growth hormone deficiency type II.

Journal: Journal of neuroendocrinology20071101

Title: The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle.

Journal: Cell metabolism20071101

Title: Heat Shock Protein 90 regulates the stability of c-Jun in HEK293 Cells.

Journal: Molecules and cells20071031

Title: Inhibition of estrogen action by 2-phenylchromone as AhR agonist in MCF-7 cells.

Journal: Life sciences20071027

Title: Regulation of repp86 stability by human Siah2.

Journal: Biochemical and biophysical research communications20071019

Title: Caspase-8 dependent osteosarcoma cell apoptosis induced by proteasome inhibitor MG132.

Journal: Cell biology international20071001

Title: Human GCIP interacts with CT847, a novel Chlamydia trachomatis type III secretion substrate, and is degraded in a tissue-culture infection model.

Journal: Cellular microbiology20071001

Title: Induction of death receptor 5 and suppression of survivin contribute to sensitization of TRAIL-induced cytotoxicity by quercetin in non-small cell lung cancer cells.

Journal: Carcinogenesis20071001

Title: Hypoxia stabilizes type 2 deiodinase activity in rat astrocytes.

Journal: Endocrinology20071001

Title: Cell cycle-and proteasome-dependent formation of etoposide-induced replication protein A (RPA) or Mre11/Rad50/Nbs1 (MRN) complex repair foci.

Journal: Cell cycle (Georgetown, Tex.)20071001

Title: PERK-dependent compartmentalization of ERAD and unfolded protein response machineries during ER stress.

Journal: Experimental cell research20071001

Title: Ascorbate (vitamin C) induces cell death through the apoptosis-inducing factor in human breast cancer cells.

Journal: Oncology reports20071001

Title: The proteasome and intracellular redox status: implications for apoptotic regulation in lens epithelial cells.

Journal: Current eye research20071001

Title: House dust mite induces expression of intercellular adhesion molecule-1 in EoL-1 human eosinophilic leukemic cells.

Journal: Journal of Korean medical science20071001

Title: EF24 induces G2/M arrest and apoptosis in cisplatin-resistant human ovarian cancer cells by increasing PTEN expression.

Journal: The Journal of biological chemistry20070928

Title: Hsp70-GlcNAc-binding activity is released by stress, proteasome inhibition, and protein misfolding.

Journal: Biochemical and biophysical research communications20070921

Title: Intramolecular disulfide bond is a critical check point determining degradative fates of ATP-binding cassette (ABC) transporter ABCG2 protein.

Journal: The Journal of biological chemistry20070921

Title: Inhibitors of the proteasome suppress homologous DNA recombination in mammalian cells.

Journal: Cancer research20070915

Title: Topoisomerase IIbeta mediated DNA double-strand breaks: implications in doxorubicin cardiotoxicity and prevention by dexrazoxane.

Journal: Cancer research20070915

Title: Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex.

Journal: The Journal of biological chemistry20070907

Title: Therapeutic proteasome inhibition in experimental acute pancreatitis.

Journal: World journal of gastroenterology20070907

Title: SCRAPPER-dependent ubiquitination of active zone protein RIM1 regulates synaptic vesicle release.

Journal: Cell20070907

Title: Histone deacetylase degradation and MEF2 activation promote the formation of slow-twitch myofibers.

Journal: The Journal of clinical investigation20070904

Title: Regulation of the cell cycle inhibitor p27 and its ubiquitin ligase Skp2 in differentiation of human embryonic stem cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20070901

Title: The role of androgen in determining differentiation and regulation of androgen receptor expression in the human prostatic epithelium transient amplifying population.

Journal: Journal of cellular physiology20070901

Title: Increased wild-type p53-induced phosphatase 1 (Wip1 or PPM1D) expression correlated with downregulation of checkpoint kinase 2 in human gastric carcinoma.

Journal: Pathology international20070901

Title: Oriental herbs as a source of novel anti-androgen and prostate cancer chemopreventive agents.

Journal: Acta pharmacologica Sinica20070901

Title: HDAC6 controls major cell response pathways to cytotoxic accumulation of protein aggregates.

Journal: Genes & development20070901

Title: DBC2 resistance is achieved by enhancing 26S proteasome-mediated protein degradation.

Journal: Biochemical and biophysical research communications20070831

Title: Proteasome-dependent degradation of guanosine 5'-triphosphate cyclohydrolase I causes tetrahydrobiopterin deficiency in diabetes mellitus.

Journal: Circulation20070821

Title: NAC1 regulates the recruitment of the proteasome complex into dendritic spines.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20070815

Title: Translational repression of MCL-1 couples stress-induced eIF2 alpha phosphorylation to mitochondrial apoptosis initiation.

Journal: The Journal of biological chemistry20070803

Title: Cyclin B1 proteolysis via p38 MAPK signaling participates in G2 checkpoint elicited by arsenite.

Journal: Journal of cellular physiology20070801

Title: COX-2 expression induced by diesel particles involves chromatin modification and degradation of HDAC1.

Journal: American journal of respiratory cell and molecular biology20070801

Title: Maspin augments proteasome inhibitor-induced apoptosis in prostate cancer cells.

Journal: Journal of cellular physiology20070801

Title: Human hydroxysteroid sulfotransferase SULT2B1 pharmacogenomics: gene sequence variation and functional genomics.

Journal: The Journal of pharmacology and experimental therapeutics20070801

Title: A comparative study of proteasomal inhibition and apoptosis induced in N27 mesencephalic cells by dopamine and MG132.

Journal: Journal of neurochemistry20070801

Title: Reprogramming following somatic cell nuclear transfer in primates is dependent upon nuclear remodeling.

Journal: Human reproduction (Oxford, England)20070801

Title: Sperm proteasomes are responsible for the acrosome reaction and sperm penetration of the vitelline envelope during fertilization of the sea urchin Pseudocentrotus depressus.

Journal: Developmental biology20070801

Title: Transcriptional activation and posttranscriptional modification of Cyp1a1 by arsenite, cadmium, and chromium.

Journal: Toxicology letters20070801

Title: Linking of autophagy to ubiquitin-proteasome system is important for the regulation of endoplasmic reticulum stress and cell viability.

Journal: The American journal of pathology20070801

Title: Control of chronic pain by the ubiquitin proteasome system in the spinal cord.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20070801

Title: An endogenous serine/threonine protein phosphatase inhibitor, G-substrate, reduces vulnerability in models of Parkinson's disease.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20070801

Title: Proteasome function is required for DNA damage response and fanconi anemia pathway activation.

Journal: Cancer research20070801

Title: Hsp70B' regulation and function.

Journal: Cell stress & chaperones20070801

Title: The Cdc25A is involved in S-phase checkpoint induced by benzo(a)pyrene.

Journal: Toxicology20070731

Title: ABA modulates the degradation of phosphoenolpyruvate carboxylase kinase in sorghum leaves.

Journal: FEBS letters20070724

Title: Characterization of the physiological turnover of native and inactivated cytochromes P450 3A in cultured rat hepatocytes: a role for the cytosolic AAA ATPase p97?

Journal: Biochemistry20070703

Title: Different induction of GRP78 and CHOP as a predictor of sensitivity to proteasome inhibitors in thyroid cancer cells.

Journal: Endocrinology20070701

Title: Hypoxic upregulation of glucose transporters in BeWo choriocarcinoma cells is mediated by hypoxia-inducible factor-1.

Journal: American journal of physiology. Cell physiology20070701

Title: Effects of proteasome inhibitors on fertilization of the sea urchin Anthocidaris crassispina.

Journal: Biological & pharmaceutical bulletin20070701

Title: Downregulation of p63 upon exposure to bile salts and acid in normal and cancer esophageal cells in culture.

Journal: American journal of physiology. Gastrointestinal and liver physiology20070701

Title: A proteomic approach towards the Hsp90-dependent ubiquitinylated proteome.

Journal: Proteomics20070701

Title: Specific blockage of ligand-induced degradation of the Ah receptor by proteasome but not calpain inhibitors in cell culture lines from different species.

Journal: Biochemical pharmacology20070630

Title: Long-term memory consolidation depends on proteasome activity in the crab Chasmagnathus.

Journal: Neuroscience20070615

Title: Effect of a single nucleotide polymorphism in the murine double minute 2 promoter (SNP309) on the sensitivity to topoisomerase II-targeting drugs.

Journal: Cancer research20070615

Title: The co-chaperone CHIP is induced in various stresses and confers protection to cells.

Journal: Biochemical and biophysical research communications20070608

Title: Liver-X-receptor activator prevents homocysteine-induced production of IgG antibodies from murine B lymphocytes via the ROS-NF-kappaB pathway.

Journal: Biochemical and biophysical research communications20070608

Title: Involvement of the betaTrCP in the ubiquitination and stability of the HIV-1 Vpu protein.

Journal: Biochemical and biophysical research communications20070608

Title: CLCP1 interacts with semaphorin 4B and regulates motility of lung cancer cells.

Journal: Oncogene20070607

Title: TNF-alpha upregulates VCAM-1 and NF-kappaB in fibroblasts from nasal polyps.

Journal: Auris, nasus, larynx20070601

Title: Induction of cyclooxygenase-2 expression by manganese in cultured astrocytes.

Journal: Neurochemistry international20070601

Title: p45, an ATPase subunit of the 19S proteasome, targets the polyglutamine disease protein ataxin-3 to the proteasome.

Journal: Journal of neurochemistry20070601

Title: Retrodifferentiation and rejuvenation of senescent monocytic cells requires PARP-1.

Journal: Experimental gerontology20070601

Title: Interaction of Toll-like receptors with bacterial components induces expression of CDX2 and MUC2 in rat biliary epithelium in vivo and in culture.

Journal: Laboratory investigation; a journal of technical methods and pathology20070601

Title: BubR1 and CENP-E have antagonistic effects upon the stability of microtubule-kinetochore attachments in Drosophila S2 cell mitosis.

Journal: Cell cycle (Georgetown, Tex.)20070601

Title: Adrenoleukodystrophy: subcellular localization and degradation of adrenoleukodystrophy protein (ALDP/ABCD1) with naturally occurring missense mutations.

Journal: Journal of neurochemistry20070601

Title: Differential regulation of estrogen receptor alpha turnover and transactivation by Mdm2 and stress-inducing agents.

Journal: Cancer research20070601

Title: In vivo effects of an inhibitor of nuclear factor-kappa B on thrombogenic properties of antiphospholipid antibodies.

Journal: Annals of the New York Academy of Sciences20070601

Title: Energy-dependent nucleolar localization of p53 in vitro requires two discrete regions within the p53 carboxyl terminus.

Journal: Oncogene20070531

Title: Role of epidermal growth factor receptor degradation in gemcitabine-mediated cytotoxicity.

Journal: Oncogene20070517

Title: The proteasome function is required for Mycobacterium leprae-induced apoptosis and cytokine secretion.

Journal: Immunology letters20070515

Title: The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.

Journal: Cancer research20070515

Title: Synthesis and pharmacological evaluation of a selected library of new potential anti-inflammatory agents bearing the gamma-hydroxybutenolide scaffold: a new class of inhibitors of prostanoid production through the selective modulation of microsomal prostaglandin E synthase-1 expression.

Journal: Journal of medicinal chemistry20070503

Title: Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells.

Journal: Carcinogenesis20070501

Title: Expression of islet inducible nitric oxide synthase and inhibition of glucose-stimulated insulin release after long-term lipid infusion in the rat is counteracted by PACAP27.

Journal: American journal of physiology. Endocrinology and metabolism20070501

Title: Molecular mechanisms involved in interleukin-4-induced human neutrophils: expression and regulation of suppressor of cytokine signaling.

Journal: Journal of leukocyte biology20070501

Title: Hydroxyurea increases eNOS protein levels through inhibition of proteasome activity.

Journal: Nitric oxide : biology and chemistry20070501

Title: Protein kinase C-ERK1/2 signal pathway switches glucose depletion-induced necrosis to apoptosis by regulating superoxide dismutases and suppressing reactive oxygen species production in A549 lung cancer cells.

Journal: Journal of cellular physiology20070501

Title: Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease.

Journal: Journal of cell science20070501

Title: Stress-induced retrotranslocation of clusterin/ApoJ into the cytosol.

Journal: Traffic (Copenhagen, Denmark)20070501

Title: Mouse homologue of yeast Prp19 interacts with mouse SUG1, the regulatory subunit of 26S proteasome.

Journal: Biochemical and biophysical research communications20070427

Title: Recruitment of activated IRF-3 and CBP/p300 to herpes simplex virus ICP0 nuclear foci: Potential role in blocking IFN-beta induction.

Journal: Virology20070410

Title: Action spectrum of Drosophila cryptochrome.

Journal: The Journal of biological chemistry20070406

Title: Phytochemicals induce breast cancer resistance protein in Caco-2 cells and enhance the transport of benzo[a]pyrene-3-sulfate.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20070401

Title: Retinol decreases beta-catenin protein levels in retinoic acid-resistant colon cancer cell lines.

Journal: Molecular carcinogenesis20070401

Title: Proteasome inhibitors sensitize ovarian cancer cells to TRAIL induced apoptosis.

Journal: Apoptosis : an international journal on programmed cell death20070401

Title: CHIP and HSPs interact with beta-APP in a proteasome-dependent manner and influence Abeta metabolism.

Journal: Human molecular genetics20070401

Title: Lafora disease proteins malin and laforin are recruited to aggresomes in response to proteasomal impairment.

Journal: Human molecular genetics20070401

Title: Interleukin-1beta inhibits the hypoxic inducibility of the erythropoietin enhancer by suppressing hepatocyte nuclear factor-4alpha.

Journal: Cellular and molecular life sciences : CMLS20070401

Title: Proteasome inhibition specifically sensitizes leukemic cells to anthracyclin-induced apoptosis through the accumulation of Bim and Bax pro-apoptotic proteins.

Journal: Cancer biology & therapy20070401

Title: Peroxisome proliferator-activated receptor gamma-independent suppression of androgen receptor expression by troglitazone mechanism and pharmacologic exploitation.

Journal: Cancer research20070401

Title: Immunosuppressive and anti-angiogenic sphingosine 1-phosphate receptor-1 agonists induce ubiquitinylation and proteasomal degradation of the receptor.

Journal: The Journal of biological chemistry20070323

Title: Synthesis, structure, and estrogenic activity of 4-amino-3-(2-methylbenzyl)coumarins on human breast carcinoma cells.

Journal: Bioorganic & medicinal chemistry20070315

Title: Expression, protein stability and transcriptional activity of retinoic acid receptors are affected by microtubules interfering agents and all-trans-retinoic acid in primary rat hepatocytes.

Journal: Molecular and cellular endocrinology20070315

Title: [Role of MG132, a proteasome inhibitor, in inducing expression of costimulatory molecules CD86 in leukemic cells and its effect on allogeneic mixed lymphocyte reaction].

Journal: Zhonghua yi xue za zhi20070313

Title: [The effect of selectively inhibiting the nuclear factor kappaB activation on survivin expression in leukemic cells].

Journal: Zhonghua yi xue za zhi20070313

Title: A histidine-rich cluster mediates the ubiquitination and degradation of the human zinc transporter, hZIP4, and protects against zinc cytotoxicity.

Journal: The Journal of biological chemistry20070309

Title: Proteasome function is required for activation of programmed cell death in heat shocked tobacco Bright-Yellow 2 cells.

Journal: FEBS letters20070306

Title: Curcumin suppresses AP1 transcription factor-dependent differentiation and activates apoptosis in human epidermal keratinocytes.

Journal: The Journal of biological chemistry20070302

Title: Glutamate stimulates glutamate receptor interacting protein 1 degradation by ubiquitin-proteasome system to regulate surface expression of GluR2.

Journal: Neuroscience20070302

Title: Activation of non-canonical NF-kappaB pathway mediated by STP-A11, an oncoprotein of Herpesvirus saimiri.

Journal: Virology20070301

Title: Two N-linked glycans are required to maintain the transport activity of the bile salt export pump (ABCB11) in MDCK II cells.

Journal: American journal of physiology. Gastrointestinal and liver physiology20070301

Title: Defective hepatocyte aquaporin-8 expression and reduced canalicular membrane water permeability in estrogen-induced cholestasis.

Journal: American journal of physiology. Gastrointestinal and liver physiology20070301

Title: Inhibition of agonist-induced down-regulation of the delta-opioid receptor with a proteasome inhibitor attenuates opioid tolerance in human embryonic kidney 293 cells.

Journal: The Journal of pharmacology and experimental therapeutics20070301

Title: p53-dependent neuronal cell death in a DJ-1-deficient zebrafish model of Parkinson's disease.

Journal: Journal of neurochemistry20070301

Title: Accumulation of retinoid X receptor-alpha in uterine leiomyomas is associated with a delayed ligand-dependent proteasome-mediated degradation and an alteration of its transcriptional activity.

Journal: Molecular endocrinology (Baltimore, Md.)20070301

Title: Expression of a mutant p193/CUL7 molecule confers resistance to MG132- and etoposide-induced apoptosis independent of p53 or Parc binding.

Journal: Biochimica et biophysica acta20070301

Title: p27 degradation by an ellipticinium series of compound via ubiquitin-proteasome pathway.

Journal: Cancer biology & therapy20070301

Title: A coordinated action of Bax, PUMA, and p53 promotes MG132-induced mitochondria activation and apoptosis in colon cancer cells.

Journal: Molecular cancer therapeutics20070301

Title: Proteasome inhibition induces glutathione synthesis and protects cells from oxidative stress: relevance to Parkinson disease.

Journal: The Journal of biological chemistry20070216

Title: Suppression of the hypoxia-inducible factor-1 response in cervical carcinoma xenografts by proteasome inhibitors.

Journal: Cancer research20070215

Title: Absence of reciprocal feedback between MPF and ERK2 MAP kinase in mitotic Xenopus laevis embryo cell-free extract.

Journal: Cell cycle (Georgetown, Tex.)20070215

Title: Proteasome inhibition-induces endoplasmic reticulum dysfunction and cell death of human cholangiocarcinoma cells.

Journal: World journal of gastroenterology20070214

Title: Proteomic expression analysis of cardiomyocytes subjected to proteasome inhibition.

Journal: Biochemical and biophysical research communications20070209

Title: Involvement of Ca2+-dependent proteasome in the degradation of both cyclin B1 and Mos during spontaneous activation of matured rat oocytes.

Journal: Theriogenology20070201

Title: Differential involvement of NF-kappaB and MAP kinase pathways in the generation of inflammatory cytokines by human neutrophils.

Journal: Journal of leukocyte biology20070201

Title: Turnover of StAR protein: roles for the proteasome and mitochondrial proteases.

Journal: Molecular and cellular endocrinology20070201

Title: A novel interaction between N-myristoylation and the 26S proteasome during cell morphogenesis.

Journal: Molecular microbiology20070201

Title: Transforming growth factor-beta, estrogen, and progesterone converge on the regulation of p27Kip1 in the normal and malignant endometrium.

Journal: Cancer research20070201

Title: NF-kappaB-independent sensitization of glioblastoma cells for TRAIL-induced apoptosis by proteasome inhibition.

Journal: Oncogene20070125

Title: Degradation of NFAT5, a transcriptional regulator of osmotic stress-related genes, is a critical event for doxorubicin-induced cytotoxicity in cardiac myocytes.

Journal: The Journal of biological chemistry20070112

Title: Sulindac induces specific degradation of the HPV oncoprotein E7 and causes growth arrest and apoptosis in cervical carcinoma cells.

Journal: Cancer letters20070108

Title: The platelet-derived growth factor receptor alpha is destabilized by geldanamycins in cancer cells.

Journal: The Journal of biological chemistry20070105

Title: Proteasome dysfunction inhibits surfactant protein gene expression in lung epithelial cells: mechanism of inhibition of SP-B gene expression.

Journal: American journal of physiology. Lung cellular and molecular physiology20070101

Title: Purification and characterization of C-terminal truncated forms of histone H2A in monocytic THP-1 cells.

Journal: The international journal of biochemistry & cell biology20070101

Title: Proteasome activator enhances survival of Huntington's disease neuronal model cells.

Journal: PloS one20070101

Title: Amino acids and insulin act additively to regulate components of the ubiquitin-proteasome pathway in C2C12 myotubes.

Journal: BMC molecular biology20070101

Title: A homeostatic model of IkappaB metabolism to control constitutive NF-kappaB activity.

Journal: Molecular systems biology20070101

Title: Effect of enucleation on inactivation of cytostatic factor activity in matured rat oocytes.

Journal: Cloning and stem cells20070101

Title: Study on the putative contribution of caspases and the proteasome to the degradation of Aph-1a and Pen-2.

Journal: Neuro-degenerative diseases20070101

Title: Degradation of the non-palmitoylated invertebrate visual guanine-nucleotide binding protein, iGq alpha(C3,4A), by the ubiquitin-proteasomal pathway is regulated by its activation and translocation to the cytoplasm.

Journal: Visual neuroscience20070101

Title: The effects of delayed activation and MG132 treatment on nuclear remodeling and preimplantation development of embryos cloned by electrofusion are correlated with the age of recipient cytoplasts.

Journal: Cloning and stem cells20070101

Title: Ubiquitin-dependent distribution of the transcriptional coactivator p300 in cytoplasmic inclusion bodies.

Journal: Epigenetics20070101

Title: Knockdown of NHERF1 enhances degradation of temperature rescued DeltaF508 CFTR from the cell surface of human airway cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20070101

Title: Proteasome inhibition potentiates the cytotoxic effects of hyperthermia in HT-29 colon cancer cells through inhibition of heat shock protein 27.

Journal: Oncology20070101

Title: Effect of proteasome inhibition on toxicity and CYP3A23 induction in cultured rat hepatocytes: comparison with arsenite.

Journal: Toxicology and applied pharmacology20061215

Title: NF-kB inhibition as a strategy to enhance etoposide-induced apoptosis in K562 cell line.

Journal: American journal of hematology20061201

Title: Ligand-dependent and -independent degradation of the human aryl hydrocarbon receptor (hAHR) in cell culture models.

Journal: Chemico-biological interactions20061201

Title: Histone deacetylase inhibitor reduces monocyte adhesion to endothelium through the suppression of vascular cell adhesion molecule-1 expression.

Journal: Arteriosclerosis, thrombosis, and vascular biology20061201

Title: Cellular FLICE-inhibitory protein down-regulation contributes to celecoxib-induced apoptosis in human lung cancer cells.

Journal: Cancer research20061201

Title: Histone deacetylase inhibitor enhances 5-fluorouracil cytotoxicity by down-regulating thymidylate synthase in human cancer cells.

Journal: Molecular cancer therapeutics20061201

Title: The proteasome inhibitor MG-132 protects hypoxic SiHa cervical carcinoma cells after cyclic hypoxia/reoxygenation from ionizing radiation.

Journal: Neoplasia (New York, N.Y.)20061201

Title: Regulation of amino acid transporter ATA2 by ubiquitin ligase Nedd4-2.

Journal: The Journal of biological chemistry20061124

Title: Proteasome inhibition induces both pro- and anti-cell death pathways in prostate cancer cells.

Journal: Cancer letters20061118

Title: The internalization and degradation of human copper transporter 1 following cisplatin exposure.

Journal: Cancer research20061115

Title: Phosphorylation-independent ubiquitylation and endocytosis of Fc gammaRIIA.

Journal: The Journal of biological chemistry20061103

Title: Coupling caspase cleavage and ubiquitin-proteasome-dependent degradation of SSRP1 during apoptosis.

Journal: Cell death and differentiation20061101

Title: Taxol and tau overexpression induced calpain-dependent degradation of the microtubule-destabilizing protein SCG10.

Journal: Experimental neurology20061101

Title: The interleukin 1beta-induced expression of human prostaglandin F2alpha receptor messenger RNA in human myometrial-derived ULTR cells requires the transcription factor, NFkappaB.

Journal: Biology of reproduction20061101

Title: Increased level of p27 subunit of proteasomes and its co-localization with tyrosinase in amelanotic melanoma cells indicate its direct role in the regulation of melanin biosynthesis.

Journal: Cell biology international20061101

Title: Curcumin inhibits hypoxia-inducible factor-1 by degrading aryl hydrocarbon receptor nuclear translocator: a mechanism of tumor growth inhibition.

Journal: Molecular pharmacology20061101

Title: Calpain mediates the dioxin-induced activation and down-regulation of the aryl hydrocarbon receptor.

Journal: Molecular pharmacology20061101

Title: Inhibition of Aurora kinases perturbs chromosome alignment and spindle checkpoint signaling in rat spermatocytes.

Journal: Experimental cell research20061101

Title: Heat induced release of Hsp70 from prostate carcinoma cells involves both active secretion and passive release from necrotic cells.

Journal: International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group20061101

Title: Effect of aspirin on the Wnt/beta-catenin pathway is mediated via protein phosphatase 2A.

Journal: Oncogene20061019

Title: Regulation of expression of BIK proapoptotic protein in human breast cancer cells: p53-dependent induction of BIK mRNA by fulvestrant and proteasomal degradation of BIK protein.

Journal: Cancer research20061015

Title: Differential effects of NF-kappaB on apoptosis induced by DNA-damaging agents: the type of DNA damage determines the final outcome.

Journal: Oncogene20061012

Title: Repression of androgen receptor in prostate cancer cells by phenethyl isothiocyanate.

Journal: Carcinogenesis20061001

Title: Modulation of inflammatory response in sepsis by proteasome inhibition.

Journal: International journal of experimental pathology20061001

Title: Suppression of human lens epithelial cell proliferation by proteasome inhibition, a potential defense against posterior capsular opacification.

Journal: Investigative ophthalmology & visual science20061001

Title: Nitric oxide-induced down-regulation of beta-catenin in colon cancer cells by a proteasome-independent specific pathway.

Journal: Gastroenterology20061001

Title: Aspirin induces apoptosis through the inhibition of proteasome function.

Journal: The Journal of biological chemistry20060929

Title: Novel thioredoxin inhibitors paradoxically increase hypoxia-inducible factor-alpha expression but decrease functional transcriptional activity, DNA binding, and degradation.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20060915

Title: The tyrosine phosphatase HD-PTP is regulated by FGF-2 through proteasome degradation.

Journal: Frontiers in bioscience : a journal and virtual library20060901

Title: Multilevel regulation of leptin storage, turnover, and secretion by feeding and insulin in rat adipose tissue.

Journal: Journal of lipid research20060901

Title: Proteasome inhibitor MG-132 induces dopaminergic degeneration in cell culture and animal models.

Journal: Neurotoxicology20060901

Title: Akt and Mammalian target of rapamycin regulate separate systems of proteolysis in renal tubular cells.

Journal: Journal of the American Society of Nephrology : JASN20060901

Title: Local sharing as a predominant determinant of synaptic matrix molecular dynamics.

Journal: PLoS biology20060901

Title: Pressure-induced regulation of IL-6 in retinal glial cells: involvement of the ubiquitin/proteasome pathway and NFkappaB.

Journal: Investigative ophthalmology & visual science20060901

Title: Flavopiridol induces cellular FLICE-inhibitory protein degradation by the proteasome and promotes TRAIL-induced early signaling and apoptosis in breast tumor cells.

Journal: Cancer research20060901

Title: UbcH7 interacts with the glucocorticoid receptor and mediates receptor autoregulation.

Journal: The Journal of endocrinology20060901

Title: Proteolytic turnover of the Gal4 transcription factor is not required for function in vivo.

Journal: Nature20060831

Title: Dynamic translational and proteasomal regulation of fragile X mental retardation protein controls mGluR-dependent long-term depression.

Journal: Neuron20060817

Title: Novel covalent modifications of alpha-synuclein during the recovery from proteasomal dysfunction.

Journal: Biochemical and biophysical research communications20060811

Title: Photoactivated phytochrome induces rapid PIF3 phosphorylation prior to proteasome-mediated degradation.

Journal: Molecular cell20060804

Title: The Spen homolog Msx2-interacting nuclear target protein interacts with the E2 ubiquitin-conjugating enzyme UbcH8.

Journal: Molecular and cellular biochemistry20060801

Title: Mechanisms of glucosamine-induced suppression of the hepatic assembly and secretion of apolipoprotein B-100-containing lipoproteins.

Journal: Journal of lipid research20060801

Title: Roles of the ubiquitin/proteasome pathway in pollen tube growth with emphasis on MG132-induced alterations in ultrastructure, cytoskeleton, and cell wall components.

Journal: Plant physiology20060801

Title: Apoptotic effect of ethyl-4-isothiocyanatobutanoate is associated with DNA damage, proteasomal activity and induction of p53 and p21cip1/waf1.

Journal: Apoptosis : an international journal on programmed cell death20060801

Title: Cloning and characterization of a novel isoform of iodotyrosine dehalogenase 1 (DEHAL1) DEHAL1C from human thyroid: comparisons with DEHAL1 and DEHAL1B.

Journal: Thyroid : official journal of the American Thyroid Association20060801

Title: Cyclin B dissociation from CDK1 precedes its degradation upon MPF inactivation in mitotic extracts of Xenopus laevis embryos.

Journal: Cell cycle (Georgetown, Tex.)20060801

Title: [Inhibitory effect of carbamazepine on proliferation of estrogen-dependent breast cancer cells].

Journal: Ai zheng = Aizheng = Chinese journal of cancer20060801

Title: A CK2-dependent mechanism for degradation of the PML tumor suppressor.

Journal: Cell20060728

Title: Geminin is essential to prevent endoreduplication and to form pluripotent cells during mammalian development.

Journal: Genes & development20060715

Title: CaMKII-independent effects of KN93 and its inactive analog KN92: reversible inhibition of L-type calcium channels.

Journal: Biochemical and biophysical research communications20060714

Title: Specific positive and negative effects of FLIP on cell survival in human prostate cancer.

Journal: Carcinogenesis20060701

Title: Modulation of IgE-dependent COX-2 gene expression by reactive oxygen species in human neutrophils.

Journal: Journal of leukocyte biology20060701

Title: The TRAIL apoptotic pathway mediates proteasome inhibitor induced apoptosis in primary chronic lymphocytic leukemia cells.

Journal: Apoptosis : an international journal on programmed cell death20060701

Title: Cannabinoid signalling in TNF-alpha induced IL-8 release.

Journal: European journal of pharmacology20060701

Title: Cholesterol depletion facilitates ubiquitylation of NPC1 and its association with SKD1/Vps4.

Journal: Journal of cell science20060701

Title: In vivo heteromer formation. Expression of soluble betaA4-crystallin requires coexpression of a heteromeric partner.

Journal: The FEBS journal20060701

Title: IL-25 regulates the expression of adhesion molecules on eosinophils: mechanism of eosinophilia in allergic inflammation.

Journal: Allergy20060701

Title: Altered cleavage and localization of PINK1 to aggresomes in the presence of proteasomal stress.

Journal: Journal of neurochemistry20060701

Title: Acetylcholine inhibits the hypoxia-induced reduction of connexin43 protein in rat cardiomyocytes.

Journal: Journal of pharmacological sciences20060701

Title: Dipeptidyl peptidase II and leukocyte cell death.

Journal: Biochemical pharmacology20060628

Title: Proteasome inhibitor MG-132 enhances whole-body protein turnover in rat.

Journal: Biochemical and biophysical research communications20060623

Title: Comparative selectivity and specificity of the proteasome inhibitors BzLLLCOCHO, PS-341, and MG-132.

Journal: Cancer research20060615

Title: Nontoxic proteasome inhibition activates a protective antioxidant defense response in endothelial cells.

Journal: Free radical biology & medicine20060615

Title: Halofuginone induces matrix metalloproteinases in rat hepatic stellate cells via activation of p38 and NFkappaB.

Journal: The Journal of biological chemistry20060602

Title: Mitogen-activated protein kinases mediate arsenic-induced down-regulation of survivin in human lung adenocarcinoma cells.

Journal: Archives of toxicology20060601

Title: Grb10 mediates insulin-stimulated degradation of the insulin receptor: a mechanism of negative regulation.

Journal: American journal of physiology. Endocrinology and metabolism20060601

Title: Knockdown of Skp2 by siRNA inhibits melanoma cell growth in vitro and in vivo.

Journal: Journal of dermatological science20060601

Title: Proteasome inhibition by MG-132 induces apoptotic cell death and mitochondrial dysfunction in cultured rat brain oligodendrocytes but not in astrocytes.

Journal: Glia20060601

Title: Inhibition of p38alpha MAPK enhances proteasome inhibitor-induced apoptosis of myeloma cells by modulating Hsp27, Bcl-X(L), Mcl-1 and p53 levels in vitro and inhibits tumor growth in vivo.

Journal: Leukemia20060601

Title: Ubiquitin-proteasome-dependent degradation of mammalian ER stearoyl-CoA desaturase.

Journal: Journal of cell science20060601

Title: Cytokines differentially regulate ICAM-1 and VCAM-1 expression on human gingival fibroblasts.

Journal: Clinical and experimental immunology20060601

Title: [Leukemic stem cell targeting therapy].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20060601

Title: Inhibition of breast cancer cell growth and induction of cell death by 1,1-bis(3'-indolyl)methane (DIM) and 5,5'-dibromoDIM.

Journal: Cancer letters20060518

Title: TIMP-1 regulation of cell cycle in human breast epithelial cells via stabilization of p27(KIP1) protein.

Journal: Oncogene20060518

Title: Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and cellular properties of potent, selective proteasome inhibitors.

Journal: Journal of medicinal chemistry20060518

Title: Glucocorticoid hormones decrease proliferation of embryonic neural stem cells through ubiquitin-mediated degradation of cyclin D1.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20060517

Title: c-Jun NH(2)-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells.

Journal: Cancer research20060515

Title: Cullin 4A-mediated proteolysis of DDB2 protein at DNA damage sites regulates in vivo lesion recognition by XPC.

Journal: The Journal of biological chemistry20060512

Title: Mutations affecting beta-tubulin folding and degradation.

Journal: The Journal of biological chemistry20060512

Title: Nuclear factor-kappaB activated by capacitative Ca2+ entry enhances muscarinic receptor-mediated soluble amyloid precursor protein (sAPPalpha) release in SH-SY5Y cells.

Journal: The Journal of biological chemistry20060505

Title: Involvement of protein synthesis and degradation in long-term potentiation of Schaffer collateral CA1 synapses.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20060503

Title: SOCS-2 interferes with myotube formation and potentiates osteoblast differentiation through upregulation of JunB in C2C12 cells.

Journal: Journal of cellular physiology20060501

Title: Evidence that hypoxia-inducible factor-1 (HIF-1) mediates transcriptional activation of interleukin-1beta (IL-1beta) in astrocyte cultures.

Journal: Journal of neuroimmunology20060501

Title: Selectively enhanced radiation sensitivity in prostate cancer cells associated with proteasome inhibition.

Journal: Oncology reports20060501

Title: Role of the proteasome in TGF-beta signaling in lens epithelial cells.

Journal: Investigative ophthalmology & visual science20060501

Title: [Proteomic analysis of G2/M arrest of HL-60 cells induced by MG132].

Journal: Ai zheng = Aizheng = Chinese journal of cancer20060501

Title: Preincubation with the proteasome inhibitor MG-132 enhances proteasome activity via the Nrf2 transcription factor in aging human skin fibroblasts.

Journal: Annals of the New York Academy of Sciences20060501

Title: Calcium-sensing receptor ubiquitination and degradation mediated by the E3 ubiquitin ligase dorfin.

Journal: The Journal of biological chemistry20060428

Title: Proteasome inhibitor-induced cyclooxygenase-2 expression in Raw264.7 cells is potentiated by inhibition of c-Jun N-terminal kinase activation.

Journal: Biochemical and biophysical research communications20060421

Title: Proteasome inhibitor MG132 sensitizes HPV-positive human cervical cancer cells to rhTRAIL-induced apoptosis.

Journal: International journal of cancer20060415

Title: Nuclear factor-kappaB p65 and upregulation of interleukin-6 in retinal ischemia/reperfusion injury in rats.

Journal: Brain research20060407

Title: The E5 protein of BPV-4 interacts with the heavy chain of MHC class I and irreversibly retains the MHC complex in the Golgi apparatus.

Journal: Oncogene20060406

Title: Ubiquitin-dependent degradation of p53 protein despite phosphorylation at its N terminus by acetaminophen.

Journal: The Journal of pharmacology and experimental therapeutics20060401

Title: Up-regulation of the clusterin gene after proteotoxic stress: implication of HSF1-HSF2 heterocomplexes.

Journal: The Biochemical journal20060401

Title: Chemokine gene activation in human bone marrow-derived osteoblasts following exposure to particulate wear debris.

Journal: Journal of biomedical materials research. Part A20060401

Title: Inhibition of cardiac hypertrophy by triflusal (4-trifluoromethyl derivative of salicylate) and its active metabolite.

Journal: Molecular pharmacology20060401

Title: C-peptide signals via Galpha i to protect against TNF-alpha-mediated apoptosis of opossum kidney proximal tubular cells.

Journal: Journal of the American Society of Nephrology : JASN20060401

Title: Lysocellin, a metabolite of the novel drug 'alopestatin', induces G1 arrest and prevents cytotoxicity induced by etoposide.

Journal: International journal of oncology20060401

Title: Ubiquitin-proteasome system stress sensitizes ovarian cancer to proteasome inhibitor-induced apoptosis.

Journal: Cancer research20060401

Title: MG132 induced apoptosis is associated with p53-independent induction of pro-apoptotic Noxa and transcriptional activity of beta-catenin.

Journal: Apoptosis : an international journal on programmed cell death20060401

Title: Oncostatin M receptor-mediated signal transduction is negatively regulated by SOCS3 through a receptor tyrosine-independent mechanism.

Journal: The Journal of biological chemistry20060331

Title: Rapid degradation of Bim by the ubiquitin-proteasome pathway mediates short-term ischemic tolerance in cultured neurons.

Journal: The Journal of biological chemistry20060317

Title: Expression of the ubiquitin variant ubR48 decreases proteolytic activity in Arabidopsis and induces cell death.

Journal: Planta20060301

Title: Prolonged activation of NF-kappaB by human cytomegalovirus promotes efficient viral replication and late gene expression.

Journal: Virology20060301

Title: Proteasome blockade exerts an antifibrotic activity by coordinately down-regulating type I collagen and tissue inhibitor of metalloproteinase-1 and up-regulating metalloproteinase-1 production in human dermal fibroblasts.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20060301

Title: A novel mouse Smad4 mutation reduces protein stability and wild-type protein levels.

Journal: Mammalian genome : official journal of the International Mammalian Genome Society20060301

Title: Proteasome inhibition sensitizes hepatocellular carcinoma cells to TRAIL by suppressing caspase inhibitors and AKT pathway.

Journal: Anti-cancer drugs20060301

Title: The BTB-kelch protein LZTR-1 is a novel Golgi protein that is degraded upon induction of apoptosis.

Journal: The Journal of biological chemistry20060224

Title: Merlin facilitates ubiquitination and degradation of transactivation-responsive RNA-binding protein.

Journal: Oncogene20060223

Title: P38MAPK-dependent phosphorylation and degradation of SRC-3/AIB1 and RARalpha-mediated transcription.

Journal: The EMBO journal20060222

Title: Function and subcellular location of Ro52beta.

Journal: Biochemical and biophysical research communications20060217

Title: Inefficient proteasomal-degradation pathway stabilizes AP-2alpha and activates HER-2/neu gene in breast cancer.

Journal: International journal of cancer20060215

Title: Intracellular composition of fatty acid affects the processing and function of tyrosinase through the ubiquitin-proteasome pathway.

Journal: The Biochemical journal20060215

Title: Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis.

Journal: Experimental cell research20060215

Title: Retinoid-mediated stimulation of steroid sulfatase activity in myeloid leukemic cell lines requires RARalpha and RXR and involves the phosphoinositide 3-kinase and ERK-MAP kinase pathways.

Journal: Journal of cellular biochemistry20060201

Title: Pharmacological rescue of the dystrophin-glycoprotein complex in Duchenne and Becker skeletal muscle explants by proteasome inhibitor treatment.

Journal: American journal of physiology. Cell physiology20060201

Title: Dynamics of lipid droplet-associated proteins during hormonally stimulated lipolysis in engineered adipocytes: stabilization and lipid droplet binding of adipocyte differentiation-related protein/adipophilin.

Journal: Molecular endocrinology (Baltimore, Md.)20060201

Title: Lack of direct role of parkin in the steady-state level and aggregation of alpha-synuclein and the clearance of pre-formed aggregates.

Journal: Experimental neurology20060201

Title: Roles of Ras and extracellular signal-regulated kinase-dependent IkappaBalpha degradation in oridonin-enhanced phagocytosis of apoptotic cells by human macrophage-like U937 cells.

Journal: International immunopharmacology20060201

Title: Proteasome inhibition induces hepatic stellate cell apoptosis.

Journal: Hepatology (Baltimore, Md.)20060201

Title: Mechanisms of cell death induced by histone deacetylase inhibitors in androgen receptor-positive prostate cancer cells.

Journal: Molecular cancer research : MCR20060201

Title: E6AP and calmodulin reciprocally regulate estrogen receptor stability.

Journal: The Journal of biological chemistry20060127

Title: Dominant-negative effect of mutant valosin-containing protein in aggresome formation.

Journal: FEBS letters20060123

Title: Chemical blockage of the proteasome inhibitory function of bortezomib: impact on tumor cell death.

Journal: The Journal of biological chemistry20060113

Title: Transcriptional regulation of the NAD(P)H:quinone oxidoreductase 1 and glutathione S-transferase ya genes by mercury, lead, and copper.

Journal: Drug metabolism and disposition: the biological fate of chemicals20060101

Title: Two different stages of epidermal growth factor (EGF) receptor endocytosis are sensitive to free ubiquitin depletion produced by proteasome inhibitor MG132.

Journal: Cell biology international20060101

Title: Oxidative stress response results in increased p21WAF1/CIP1 degradation in cystic fibrosis lung epithelial cells.

Journal: Free radical biology & medicine20060101

Title: The kinase p38 regulates peroxisome proliferator activated receptor-gamma in human trophoblasts.

Journal: Placenta20060101

Title: Inhibition of TRIP1/S8/hSug1, a component of the human 19S proteasome, enhances mitotic apoptosis induced by spindle poisons.

Journal: Molecular cancer therapeutics20060101

Title: Degradation of perilipin is mediated through ubiquitination-proteasome pathway.

Journal: Biochimica et biophysica acta20060101

Title: The cyclin D1 proto-oncogene is sequestered in the cytoplasm of mammalian cancer cell lines.

Journal: Molecular cancer20060101

Title: Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.

Journal: Molecular cancer20060101

Title: Peroxynitrite induces an alternative NF-kappaB activation pathway in L8 rat myoblasts.

Journal: Antioxidants & redox signaling20060101

Title: Opposite effects of proteasome inhibitors in the adrenergic induction of arylalkylamine N-acetyltransferase in rat pinealocytes.

Journal: Chronobiology international20060101

Title: Presenilin 1 forms aggresomal deposits in response to heat shock.

Journal: Journal of molecular neuroscience : MN20060101

Title: Apoptosis induced by proteasome inhibition in human myoblast cultures.

Journal: European journal of histochemistry : EJH20060101

Title: Proteasome inhibitors eliminate protective effect of postconditioning in cultured neonatal cardiomyocytes.

Journal: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994)20060101

Title: Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels.

Journal: BMC cell biology20060101

Title: The dynamic instability of microtubules is required for aggresome formation in oligodendroglial cells after proteolytic stress.

Journal: Journal of molecular neuroscience : MN20060101

Title: Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.

Journal: Pathology oncology research : POR20060101

Title: P53 and p73 differ in their ability to inhibit glucocorticoid receptor (GR) transcriptional activity.

Journal: Molecular cancer20060101

Title: Effect of proteasome inhibitors on expression of HLA-G isoforms.

Journal: Neoplasma20060101

Title: [Artifitial increase of HIV-1 reverse transcriptase turnover through proteasome pathway].

Journal: Molekuliarnaia biologiia20060101

Title: Antiviral activity of proteasome inhibitors in herpes simplex virus-1 infection: role of nuclear factor-kappaB.

Journal: Antiviral therapy20060101

Title: Post-translational regulation of adipose differentiation-related protein by the ubiquitin/proteasome pathway.

Journal: The Journal of biological chemistry20051230

Title: hnRNP K: an HDM2 target and transcriptional coactivator of p53 in response to DNA damage.

Journal: Cell20051216

Title: Tetrahydrobiopterin depletion and ubiquitylation of neuronal nitric oxide synthase.

Journal: Brain research. Molecular brain research20051207

Title: Role of protein turnover in the activation of p38 mitogen-activated protein kinase in rat pinealocytes.

Journal: Biochemical pharmacology20051205

Title: Comparison of the SUMO1 and ubiquitin conjugation pathways during the inhibition of proteasome activity with evidence of SUMO1 recycling.

Journal: The Biochemical journal20051201

Title: Advanced glycation end-product induces fractalkine gene upregulation in normal rat glomeruli.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20051201

Title: The proteasome inhibitor MG132 induces apoptosis in human pancreatic cancer cells.

Journal: Oncology reports20051201

Title: Combination of proteasomal inhibitors lactacystin and MG132 induced synergistic apoptosis in prostate cancer cells.

Journal: Neoplasia (New York, N.Y.)20051201

Title: Evidence for proteasomal degradation of Kv1.5 channel protein.

Journal: Biochemical and biophysical research communications20051111

Title: The proteasome metabolizes peptide-mediated nonviral gene delivery systems.

Journal: Gene therapy20051101

Title: Regulatory mechanisms modulating the expression of cytochrome P450 1A1 gene by heavy metals.

Journal: Toxicological sciences : an official journal of the Society of Toxicology20051101

Title: Proteasomal proteolysis in the adrenergic induction of arylalkylamine-N-acetyltransferase in rat pinealocytes.

Journal: Endocrinology20051101

Title: Induction and attenuation of neuronal apoptosis by proteasome inhibitors in murine cortical cell cultures.

Journal: Journal of neurochemistry20051101

Title: UV-A light regulation of arylalkylamine N-acetyltransferase activity in the chick pineal gland: role of cAMP and proteasomal proteolysis.

Journal: Journal of pineal research20051101

Title: The proteasome inhibitor MG132 protects against acute pancreatitis.

Journal: Free radical biology & medicine20051101

Title: Arsenite induces endothelial cytotoxicity by down-regulation of vascular endothelial nitric oxide synthase.

Journal: Toxicology and applied pharmacology20051101

Title: Apoptosis induced by the kinase inhibitor BAY 43-9006 in human leukemia cells involves down-regulation of Mcl-1 through inhibition of translation.

Journal: The Journal of biological chemistry20051021

Title: Preliminary studies of new proteasome inhibitors in the tumor targeting approach: synthesis and in vitro cytotoxicity.

Journal: Journal of medicinal chemistry20051020

Title: Differential effect of calmodulin antagonists on MG132-induced mitochondrial dysfunction and cell death in PC12 cells.

Journal: Brain research bulletin20051015

Title: Low-level expression of proapoptotic Bcl-2-interacting mediator in leukemic cells in patients with chronic myeloid leukemia: role of BCR/ABL, characterization of underlying signaling pathways, and reexpression by novel pharmacologic compounds.

Journal: Cancer research20051015

Title: Phosphorylation of RelA/p65 on serine 536 defines an I{kappa}B{alpha}-independent NF-{kappa}B pathway.

Journal: The Journal of biological chemistry20051014

Title: Adeno-associated virus (AAV)-7 and -8 poorly transduce vascular endothelial cells and are sensitive to proteasomal degradation.

Journal: Gene therapy20051001

Title: The cyclopentenone 15-deoxy-delta(12,14)-prostaglandin J2 inhibits G1/S transition and retinoblastoma protein phosphorylation in immortalized lymphocytes from Alzheimer's disease patients.

Journal: Experimental neurology20051001

Title: Proteasome inhibition improves fractionated radiation treatment against non-small cell lung cancer: an antioxidant connection.

Journal: International journal of oncology20051001

Title: The proteasomal inhibitor MG132 increases the efficiency of mouse embryo production after cloning by electrofusion.

Journal: Reproduction (Cambridge, England)20051001

Title: Topotecan-triggered degradation of topoisomerase I is p53-dependent and impacts cell survival.

Journal: Cancer research20051001

Title: Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system.

Journal: Biological chemistry20051001

Title: [The protective effect of MG132 on post-ischemia reperfusion injury of rat livers by activation of nuclear factor kappa B].

Journal: Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology20051001

Title: Association of DJ-1 with chaperones and enhanced association and colocalization with mitochondrial Hsp70 by oxidative stress.

Journal: Free radical research20051001

Title: Exogenous auxin enhances the degradation of a light down-regulated and nuclear-localized OsiIAA1, an Aux/IAA protein from rice, via proteasome.

Journal: Biochimica et biophysica acta20050925

Title: Regulation of elastin gene transcription by proteasome dysfunction.

Journal: American journal of physiology. Cell physiology20050901

Title: Spindle pole fragmentation due to proteasome inhibition.

Journal: Journal of cellular physiology20050901

Title: Ataxia telangiectasia-mutated, a DNA damage-inducible kinase, contributes to high NaCl-induced nuclear localization of transcription factor TonEBP/OREBP.

Journal: American journal of physiology. Renal physiology20050901

Title: Depressant effect of mitochondrial respiratory complex inhibitors on proteasome inhibitor-induced mitochondrial dysfunction and cell death in PC12 cells.

Journal: Neurochemical research20050901

Title: Proteasome comprising a beta1 inducible subunit acts as a negative regulator of NADPH oxidase during elicitation of plant defense reactions.

Journal: FEBS letters20050829

Title: Protein phosphatase 2A regulates estrogen receptor alpha (ER) expression through modulation of ER mRNA stability.

Journal: The Journal of biological chemistry20050819

Title: Functional analysis of six human aryl hydrocarbon receptor variants in a Japanese population.

Journal: Drug metabolism and disposition: the biological fate of chemicals20050801

Title: Distinct IkappaB kinase regulation in adult T cell leukemia and HTLV-I-transformed cells.

Journal: Experimental cell research20050801

Title: Polyamine depletion reduces TNFalpha/MG132-induced apoptosis in bone marrow stromal cells.

Journal: Stem cells (Dayton, Ohio)20050801

Title: TGF-beta1 enhances degradation of IFN-gamma-induced iNOS protein via proteasomes in RAW 264.7 cells.

Journal: Nitric oxide : biology and chemistry20050801

Title: Proteasome inhibition by lactacystin in primary neuronal cells induces both potentially neuroprotective and pro-apoptotic transcriptional responses: a microarray analysis.

Journal: Journal of neurochemistry20050801

Title: Functional role of the AAA peroxins in dislocation of the cycling PTS1 receptor back to the cytosol.

Journal: Nature cell biology20050801

Title: Inhibition of the proteasome strongly affects cadmium stimulated laccase activity in Trametes versicolor.

Journal: Biochimie20050801

Title: Cross talk in hormonally regulated gene transcription through induction of estrogen receptor ubiquitylation.

Journal: Molecular and cellular biology20050801

Title: [Effects of MG132 , an inhibitor of proteasome , on the pollen germination and tube growth of Pecea wilsonii].

Journal: Shi yan sheng wu xue bao20050801

Title: FBI-1 enhances transcription of the nuclear factor-kappaB (NF-kappaB)-responsive E-selectin gene by nuclear localization of the p65 subunit of NF-kappaB.

Journal: The Journal of biological chemistry20050729

Title: Proteasome inhibitors abrogate osteoclast differentiation and osteoclast function.

Journal: Biochemical and biophysical research communications20050722

Title: Synergic action of insulin and genistein on Na+/K+/2Cl- cotransporter in renal epithelium.

Journal: Biochemical and biophysical research communications20050715

Title: Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo.

Journal: Experimental cell research20050715

Title: Selective induction of the tumor marker glutathione S-transferase P1 by proteasome inhibitors.

Journal: The Journal of biological chemistry20050701

Title: Eukaryotic translation initiation factor 4E is a cellular target for toxicity and death due to exposure to cadmium chloride.

Journal: The Journal of biological chemistry20050701

Title: Rapid turnover of GATA-2 via ubiquitin-proteasome protein degradation pathway.

Journal: Genes to cells : devoted to molecular & cellular mechanisms20050701

Title: Proteasome inhibitor MG132 induces death receptor 5 through CCAAT/enhancer-binding protein homologous protein.

Journal: Cancer research20050701

Title: Mechanisms of deregulation of IFN regulatory factor-1 in ras-transformed fibroblasts.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20050701

Title: Interactive effects of HDAC inhibitors and TRAIL on apoptosis are associated with changes in mitochondrial functions and expressions of cell cycle regulatory genes in multiple myeloma.

Journal: Neoplasia (New York, N.Y.)20050701

Title: Calcium-activated proteases are critical for refilling depleted vesicle stores in cultured sensory-motor synapses of Aplysia.

Journal: Learning & memory (Cold Spring Harbor, N.Y.)20050701

Title: Proteasome inhibitors-mediated TRAIL resensitization and Bik accumulation.

Journal: Cancer biology & therapy20050701

Title: Increasing expression of heme oxygenase-1 by proteasome inhibition protects astrocytes from heme-mediated oxidative injury.

Journal: Current neurovascular research20050701

Title: Ubiquitin-dependent degradation of interferon regulatory factor-8 mediated by Cbl down-regulates interleukin-12 expression.

Journal: The Journal of biological chemistry20050624

Title: Degradation of glyceraldehyde-3-phosphate dehydrogenase triggered by 4-hydroxy-2-nonenal and 4-hydroxy-2-hexenal.

Journal: Archives of biochemistry and biophysics20050615

Title: Membrane insertion of betaine/GABA transporter during hypertonic stress correlates with nuclear accumulation of TonEBP.

Journal: Biochimica et biophysica acta20050615

Title: Seliciclib (CYC202, R-Roscovitine) induces cell death in multiple myeloma cells by inhibition of RNA polymerase II-dependent transcription and down-regulation of Mcl-1.

Journal: Cancer research20050615

Title: Degradation of Saccharomyces cervisiae Rck2 upon exposure of cells to high levels of zinc is dependent on Pep4.

Journal: Molecular genetics and genomics : MGG20050601

Title: Effects of mechanistically distinct NF-kappaB inhibitors on glial inducible nitric-oxide synthase expression.

Journal: Nitric oxide : biology and chemistry20050601

Title: Induction and activation of the aryl hydrocarbon receptor by IL-4 in B cells.

Journal: International immunology20050601

Title: Upregulation of heat shock protein expression by proteasome inhibition: an antiapoptotic mechanism in the lens.

Journal: Investigative ophthalmology & visual science20050601

Title: Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20050601

Title: [Reversal of chemoresistance to vincristine in gastric cancer cells by NF-kappaB inhibitor].

Journal: Zhonghua zhong liu za zhi [Chinese journal of oncology]20050601

Title: PKCalpha is involved in phorbol ester TPA-mediated stabilization of p14ARF.

Journal: Biochemical and biophysical research communications20050520

Title: Activation of hypoxia-induced transcription in normoxia.

Journal: Experimental cell research20050515

Title: Nitric oxide reverses desferrioxamine- and hypoxia-evoked HIF-1alpha accumulation--implications for prolyl hydroxylase activity and iron.

Journal: Experimental cell research20050515

Title: Growth hormone receptor is a target for presenilin-dependent gamma-secretase cleavage.

Journal: The Journal of biological chemistry20050513

Title: Cdk2-dependent phosphorylation of homeobox transcription factor CDX2 regulates its nuclear translocation and proteasome-mediated degradation in human intestinal epithelial cells.

Journal: The Journal of biological chemistry20050506

Title: Rapamycin induces apoptosis of JN-DSRCT-1 cells by increasing the Bax : Bcl-xL ratio through concurrent mechanisms dependent and independent of its mTOR inhibitory activity.

Journal: Oncogene20050505

Title: Simvastatin inhibits MMP-9 secretion from human saphenous vein smooth muscle cells by inhibiting the RhoA/ROCK pathway and reducing MMP-9 mRNA levels.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20050501

Title: Recombinant adeno-associated virus type 2-mediated gene transfer into human keratinocytes is influenced by both the ubiquitin/proteasome pathway and epidermal growth factor receptor tyrosine kinase.

Journal: Archives of dermatological research20050501

Title: Differential roles of constitutively activated ERK1/2 and NF-kappa B in cytotoxicity and proliferation by human NK cell lines.

Journal: International immunopharmacology20050501

Title: Death receptor-mediated apoptosis in human malignant glioma cells: modulation by the CD40/CD40L system.

Journal: Journal of neuroimmunology20050501

Title: Activity probe for in vivo profiling of the specificity of proteasome inhibitor bortezomib.

Journal: Nature methods20050501

Title: The regulation of pro-inflammatory gene expression induced by pigment epithelium-derived factor in rat cultured microglial cells.

Journal: Neuroscience letters20050501

Title: [Inhibiting expression of human telomerase reverse transcriptase promotes degradation of survivin protein].

Journal: Ai zheng = Aizheng = Chinese journal of cancer20050501

Title: Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.

Journal: Blood20050415

Title: Schistosoma mansoni: functional proteasomes are required for development in the vertebrate host.

Journal: Experimental parasitology20050401

Title: Phosphorylation-dependent degradation of p300 by doxorubicin-activated p38 mitogen-activated protein kinase in cardiac cells.

Journal: Molecular and cellular biology20050401

Title: Proteasome inhibition enhances AAV-mediated transgene expression in human synoviocytes in vitro and in vivo.

Journal: Molecular therapy : the journal of the American Society of Gene Therapy20050401

Title: Cytosolic prion protein (PrP) is not toxic in N2a cells and primary neurons expressing pathogenic PrP mutations.

Journal: The Journal of biological chemistry20050325

Title: Inhibitory effect of dicationic diphenylfurans on production of type I collagen by human fibroblasts and activated hepatic stellate cells.

Journal: Life sciences20050311

Title: Proteasome inhibitors induce peroxisome proliferator-activated receptor transactivation through RXR accumulation and a protein kinase C-dependent pathway.

Journal: Experimental cell research20050310

Title: Inhibition of MG132-induced mitochondrial dysfunction and cell death in PC12 cells by 3-morpholinosydnonimine.

Journal: Brain research20050302

Title: Growth-associated protein-43 is degraded via the ubiquitin-proteasome system.

Journal: Journal of neuroscience research20050301

Title: Regulation of Wallerian degeneration and nerve growth factor withdrawal-induced pruning of axons of sympathetic neurons by the proteasome and the MEK/Erk pathway.

Journal: Molecular and cellular neurosciences20050301

Title: Does proteasome [corrected] inhibition decrease or accelerate toxin-induced dopaminergic neurodegeneration?

Journal: Journal of pharmacological sciences20050301

Title: Inhibition of the 26S proteasome blocks progesterone receptor-dependent transcription through failed recruitment of RNA polymerase II.

Journal: The Journal of steroid biochemistry and molecular biology20050301

Title: Role of the proteasome in the regulation of estrogen receptor alpha turnover and function in MCF-7 breast carcinoma cells.

Journal: The Journal of steroid biochemistry and molecular biology20050301

Title: DET1 regulates the proteasomal degradation of LHY, a component of the Arabidopsis circadian clock.

Journal: Plant molecular biology20050301

Title: 15-Deoxy-delta 12,14-prostaglandin J2 induces apoptosis in human malignant B cells: an effect associated with inhibition of NF-kappa B activity and down-regulation of antiapoptotic proteins.

Journal: Blood20050215

Title: L-dopa and dopamine enhance the formation of aggregates under proteasome inhibition in PC12 cells.

Journal: FEBS letters20050214

Title: E1AF degradation by a ubiquitin-proteasome pathway.

Journal: Biochemical and biophysical research communications20050211

Title: Proteasomal degradation of human CYP1B1: effect of the Asn453Ser polymorphism on the post-translational regulation of CYP1B1 expression.

Journal: Molecular pharmacology20050201

Title: Disruption of microtubules leads to glucocorticoid receptor degradation in HeLa cell line.

Journal: Cellular signalling20050201

Title: Herpes virus proteins ICP0 and BICP0 can activate NF-kappaB by catalyzing IkappaBalpha ubiquitination.

Journal: Cellular signalling20050201

Title: Protease inhibitor MG132 in cloning: no end to the nightmare.

Journal: Trends in biotechnology20050201

Title: Intercellular communication via gap junctions in activated rat hepatic stellate cells.

Journal: Gastroenterology20050201

Title: Contribution of high p34cdc2 kinase activity to premature chromosome condensation of injected somatic cell nuclei in rat oocytes.

Journal: Reproduction (Cambridge, England)20050201

Title: The HTLV-I Tax oncoprotein targets the retinoblastoma protein for proteasomal degradation.

Journal: Oncogene20050120

Title: Proteasome inhibition and Tau proteolysis: an unexpected regulation.

Journal: FEBS letters20050103

Title: Butyrate-induced apoptosis and cell cycle arrest in bovine kidney epithelial cells: involvement of caspase and proteasome pathways.

Journal: Journal of animal science20050101

Title: Adenosine kinase inhibitor attenuates the expression of inducible nitric oxide synthase in glial cells.

Journal: Neuropharmacology20050101

Title: Hypertonic upregulation of betaine transport in renal cells is blocked by a proteasome inhibitor.

Journal: Cell biochemistry and function20050101

Title: The proteasome inhibitor MG-132 sensitizes PC-3 prostate cancer cells to ionizing radiation by a DNA-PK-independent mechanism.

Journal: BMC cancer20050101

Title: Proteasome inhibitors abolish cell death downstream of caspase activation during anti-microtubule drug-induced apoptosis in leukemia cells.

Journal: Anticancer research20050101

Title: Anthracyclines, proteasome activity and multi-drug-resistance.

Journal: BMC cancer20050101

Title: Cell-specific inhibition of paramyxovirus maturation by proteasome inhibitors.

Journal: Microbiology and immunology20050101

Title: Interleukin-3, -5, and granulocyte macrophage colony-stimulating factor induce adhesion and chemotaxis of human eosinophils via p38 mitogen-activated protein kinase and nuclear factor kappaB.

Journal: Immunopharmacology and immunotoxicology20050101

Title: Osmotic regulation of MG-132-induced MAP-kinase phosphatase MKP-1 expression in H4IIE rat hepatoma cells.

Journal: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology20050101

Title: Proteomic analysis of ubiquitinated proteins from human MCF-7 breast cancer cells by immunoaffinity purification and mass spectrometry.

Journal: Journal of proteome research20050101

Title: Nuclear localization destabilizes the stress-regulated transcription factor Msn2.

Journal: The Journal of biological chemistry20041231

Title: c-Myc localization within the nucleus: evidence for association with the PML nuclear body.

Journal: Journal of cellular biochemistry20041215

Title: Aggresome formation and pharmacogenetics: sulfotransferase 1A3 as a model system.

Journal: Biochemical and biophysical research communications20041210

Title: Epidermal growth factor and interleukin-1beta utilize divergent signaling pathways to synergistically upregulate cyclooxygenase-2 gene expression in human amnion-derived WISH cells.

Journal: Biology of reproduction20041201

Title: Degradation of survival motor neuron (SMN) protein is mediated via the ubiquitin/proteasome pathway.

Journal: Neurochemistry international20041201

Title: A novel UBA and UBX domain protein that binds polyubiquitin and VCP and is a substrate for SAPKs.

Journal: The Biochemical journal20041201

Title: Dual role of cAMP in iNOS expression in glial cells and macrophages is mediated by differential regulation of p38-MAPK/ATF-2 activation and iNOS stability.

Journal: Free radical biology & medicine20041201

Title: Effects of proteasome inhibitors MG132, ZL3VS and AdaAhx3L3VS on protein metabolism in septic rats.

Journal: International journal of experimental pathology20041201

Title: Histone deacetylase inhibitor trichostatin A represses estrogen receptor alpha-dependent transcription and promotes proteasomal degradation of cyclin D1 in human breast carcinoma cell lines.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20041201

Title: Troglitazone inhibits cyclin D1 expression and cell cycling independently of PPARgamma in normal mouse skin keratinocytes.

Journal: The Journal of investigative dermatology20041201

Title: Ligand-independent and agonist-mediated degradation of estrogen receptor-alpha in breast carcinoma cells: evidence for distinct degradative pathways.

Journal: Molecular and cellular endocrinology20041130

Title: cAMP-dependent protein kinase regulates ubiquitin-proteasome-mediated degradation and subcellular localization of the nuclear receptor coactivator GRIP1.

Journal: The Journal of biological chemistry20041119

Title: Effects of a redox-active agent on lymphocyte activation and early gene expression patterns.

Journal: Free radical biology & medicine20041115

Title: Proteasomal interference prevents zona pellucida penetration and fertilization in mammals.

Journal: Biology of reproduction20041101

Title: Inhibiting proteasomal proteolysis sustains estrogen receptor-alpha activation.

Journal: Molecular endocrinology (Baltimore, Md.)20041101

Title: Proteasomes act in the pre-mitochondrial signal transduction route towards roscovitine-induced apoptosis.

Journal: International journal of oncology20041101

Title: Retinoic acid induces neuroblastoma cell death by inhibiting proteasomal degradation of retinoic acid receptor alpha.

Journal: Cancer research20041101

Title: A proteasomal stress response: pre-treatment with proteasome inhibitors increases proteasome activity and reduces neuronal vulnerability to oxidative injury.

Journal: Journal of neurochemistry20041101

Title: Inhibition of proteasome by MG-132 treatment causes extra phragmoplast formation and cortical microtubule disorganization during M/G1 transition in synchronized tobacco cells.

Journal: Plant & cell physiology20041101

Title: Ectopic expression of nonliganded retinoic acid receptor beta abrogates AP-1 activity by selective degradation of c-Jun in cervical carcinoma cells.

Journal: The Journal of biological chemistry20041029

Title: The Rac1 C-terminal polybasic region regulates the nuclear localization and protein degradation of Rac1.

Journal: The Journal of biological chemistry20041015

Title: Ubiquitin-proteasome pathway modulates mouse oocyte meiotic maturation and fertilization via regulation of MAPK cascade and cyclin B1 degradation.

Journal: Mechanisms of development20041001

Title: Inhibitory effect of ubiquitin-proteasome pathway on proliferation of esophageal carcinoma cells.

Journal: World journal of gastroenterology20041001

Title: Downregulation of matrix metalloproteinases and collagens and suppression of cardiac fibrosis by inhibition of the proteasome.

Journal: Hypertension (Dallas, Tex. : 1979)20041001

Title: Increased expression of p62 in expanded polyglutamine-expressing cells and its association with polyglutamine inclusions.

Journal: Journal of neurochemistry20041001

Title: Superinduction of CYP1A1 in MCF10A cultures by cycloheximide, anisomycin, and puromycin: a process independent of effects on protein translation and unrelated to suppression of aryl hydrocarbon receptor proteolysis by the proteasome.

Journal: Molecular pharmacology20041001

Title: Dual regulation of Snail by GSK-3beta-mediated phosphorylation in control of epithelial-mesenchymal transition.

Journal: Nature cell biology20041001

Title: GSK-3beta sets Snail's pace.

Journal: Nature cell biology20041001

Title: [Mechanism of G2/M cell cycle arrest before apoptosis in leukemia cell line HL-60 induced by proteasome inhibitor MG132].

Journal: Ai zheng = Aizheng = Chinese journal of cancer20041001

Title: Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells.

Journal: Toxicology and applied pharmacology20040915

Title: Proteasome-dependent degradation of cyclin D1 in 1-methyl-4-phenylpyridinium ion (MPP+)-induced cell cycle arrest.

Journal: The Journal of biological chemistry20040910

Title: In situ dynamically monitoring the proteolytic function of the ubiquitin-proteasome system in cultured cardiac myocytes.

Journal: American journal of physiology. Heart and circulatory physiology20040901

Title: Regulation of ubiquitin-proteasome pathway on pig oocyte meiotic maturation and fertilization.

Journal: Biology of reproduction20040901

Title: Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20040901

Title: Inhibition of the ubiquitin-proteasome pathway activates stress kinases and induces apoptosis in renal cancer cells.

Journal: International journal of oncology20040901

Title: The proteasome inhibitor, MG132, promotes the reprogramming of translation in C2C12 myoblasts and facilitates the association of hsp25 with the eIF4F complex.

Journal: European journal of biochemistry20040901

Title: Ceramide, an apoptotic rheostat, inhibits CCAAT/enhancer binding protein-beta and NF-E2-related factor-2 activation: the role in glutathione S-transferase A2 gene repression.

Journal: Drug metabolism and disposition: the biological fate of chemicals20040901

Title: Nrf2 is a key transcription factor that regulates antioxidant defense in macrophages and epithelial cells: protecting against the proinflammatory and oxidizing effects of diesel exhaust chemicals.

Journal: Journal of immunology (Baltimore, Md. : 1950)20040901

Title: Nitric oxide acts on the mitochondria and protects human endothelial cells from apoptosis.

Journal: The Journal of laboratory and clinical medicine20040901

Title: Differential response of MG132 cytotoxicity against small cell lung cancer cells to changes in cellular GSH contents.

Journal: Biochemical pharmacology20040815

Title: Phosphorylation of the histone deacetylase 7 modulates its stability and association with 14-3-3 proteins.

Journal: The Journal of biological chemistry20040813

Title: c-Fos phosphorylation induced by H2O2 prevents proteasomal degradation of c-Fos in cardiomyocytes.

Journal: The Journal of biological chemistry20040806

Title: Fertilization and InsP3-induced Ca2+ release stimulate a persistent increase in the rate of degradation of cyclin B1 specifically in mature mouse oocytes.

Journal: Developmental biology20040801

Title: Regulation of IFN regulatory factor-7 and IFN-alpha production by enveloped virus and lipopolysaccharide in human plasmacytoid dendritic cells.

Journal: Journal of immunology (Baltimore, Md. : 1950)20040801

Title: Inhibition of constitutively activated nuclear factor-kappaB radiosensitizes human melanoma cells.

Journal: Molecular cancer therapeutics20040801

Title: The Ah receptor inhibits estrogen-induced estrogen receptor beta in breast cancer cells.

Journal: Biochemical and biophysical research communications20040716

Title: HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function.

Journal: Oncogene20040701

Title: Human hRad1 but not hRad9 protects hHus1 from ubiquitin-proteasomal degradation.

Journal: Oncogene20040701

Title: Reactive oxygen species mediate chloroquine-induced expression of chemokines by human astroglial cells.

Journal: Glia20040701

Title: The ubiquitin-proteasome machinery is essential for nuclear translocation of incoming minute virus of mice.

Journal: Virology20040701

Title: Glial cell line-derived neurotrophic factor enhances nuclear factor-kappaB activity and invasive potential in human pancreatic cancer cells.

Journal: Pancreas20040701

Title: Estrogen responsiveness of IBEP-2, a new human cell line derived from breast carcinoma.

Journal: Breast cancer research and treatment20040701

Title: Mechanism of NF-kappaB inactivation induced by survival signal withdrawal in cerebellar granule neurons.

Journal: The European journal of neuroscience20040701

Title: Down-regulation of melanogenesis by phospholipase D2 through ubiquitin proteasome-mediated degradation of tyrosinase.

Journal: The Journal of biological chemistry20040625

Title: Granulocyte macrophage colony-stimulating factor signaling and proteasome inhibition delay neutrophil apoptosis by increasing the stability of Mcl-1.

Journal: The Journal of biological chemistry20040625

Title: Rapid degradation of Cdt1 upon UV-induced DNA damage is mediated by SCFSkp2 complex.

Journal: The Journal of biological chemistry20040625

Title: High glucose down-regulates intercellular communication in retinal endothelial cells by enhancing degradation of connexin 43 by a proteasome-dependent mechanism.

Journal: The Journal of biological chemistry20040625

Title: Transcriptional activation of p62/A170/ZIP during the formation of the aggregates: possible mechanisms and the role in Lewy body formation in Parkinson's disease.

Journal: Brain research20040625

Title: Beta-adrenergic stimulation induces interleukin-18 expression via beta2-AR, PI3K, Akt, IKK, and NF-kappaB.

Journal: Biochemical and biophysical research communications20040625

Title: Proteolytic stress causes heat shock protein induction, tau ubiquitination, and the recruitment of ubiquitin to tau-positive aggregates in oligodendrocytes in culture.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20040623

Title: Endosome disruption enhances the functional nuclear delivery of Tat-fusion proteins.

Journal: Biochemical and biophysical research communications20040618

Title: Transcriptional repression of E2F gene by proteasome inhibitors in human osteosarcoma cells.

Journal: Biochemical and biophysical research communications20040611

Title: Degradation of the LDL receptor class 2 mutants is mediated by a proteasome-dependent pathway.

Journal: Journal of lipid research20040601

Title: Control of peroxisome proliferator-activated receptor gamma2 stability and activity by SUMOylation.

Journal: Obesity research20040601

Title: 15-deoxy-delta12,14-prostaglandin J2 inhibits Bay 11-7085-induced sustained extracellular signal-regulated kinase phosphorylation and apoptosis in human articular chondrocytes and synovial fibroblasts.

Journal: The Journal of biological chemistry20040521

Title: Proteasomal degradation of N-acetyltransferase 1 is prevented by acetylation of the active site cysteine: a mechanism for the slow acetylator phenotype and substrate-dependent down-regulation.

Journal: The Journal of biological chemistry20040521

Title: Hereditary early-onset Parkinson's disease caused by mutations in PINK1.

Journal: Science (New York, N.Y.)20040521

Title: Proteasome inhibitors up-regulate haem oxygenase-1 gene expression: requirement of p38 MAPK (mitogen-activated protein kinase) activation but not of NF-kappaB (nuclear factor kappaB) inhibition.

Journal: The Biochemical journal20040501

Title: CDDO induces apoptosis via the intrinsic pathway in lymphoid cells.

Journal: Leukemia20040501

Title: Induction of apoptosis by the proteasome inhibitor MG132 in human HCC cells: Possible correlation with specific caspase-dependent cleavage of beta-catenin and inhibition of beta-catenin-mediated transactivation.

Journal: International journal of molecular medicine20040501

Title: Effect of proteasome inhibitor MG132 on in vitro maturation of pig oocytes.

Journal: Zygote (Cambridge, England)20040501

Title: A cathepsin L isoform that is devoid of a signal peptide localizes to the nucleus in S phase and processes the CDP/Cux transcription factor.

Journal: Molecular cell20040423

Title: Cardiac myocytes activated by septic plasma promote neutrophil transendothelial migration: role of platelet-activating factor and the chemokines LIX and KC.

Journal: Circulation research20040416

Title: HIV-1 auxiliary regulatory protein Vpr promotes ubiquitination and turnover of Vpr mutants containing the L64P mutation.

Journal: FEBS letters20040409

Title: AP-1-independent sensitization to oxidative stress-induced apoptosis by proteasome inhibitors.

Journal: Biochemical and biophysical research communications20040402

Title: Proteasome inhibitor MG132 upregulates death receptor 5 and cooperates with Apo2L/TRAIL to induce apoptosis in Bax-proficient and -deficient cells.

Journal: Oncogene20040401

Title: Influence of p53 and p21Waf1 expression on G2/M phase arrest of colorectal carcinoma HCT116 cells to proteasome inhibitors.

Journal: International journal of oncology20040401

Title: Withdrawal of ovarian steroids stimulates prostaglandin F2alpha production through nuclear factor-kappaB activation via oxygen radicals in human endometrial stromal cells: potential relevance to menstruation.

Journal: The Journal of reproduction and development20040401

Title: Involvement of suppressor for Gal 1 in the ubiquitin/proteasome-mediated degradation of estrogen receptors.

Journal: The Journal of biological chemistry20040326

Title: Resveratrol modulates the phosphoinositide 3-kinase pathway through an estrogen receptor alpha-dependent mechanism: relevance in cell proliferation.

Journal: International journal of cancer20040320

Title: Proteasome mediates dopaminergic neuronal degeneration, and its inhibition causes alpha-synuclein inclusions.

Journal: The Journal of biological chemistry20040312

Title: Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells.

Journal: Blood20040301

Title: Proteasome inhibition increases HuR level, restores heat-inducible HSP72 expression and thermotolerance in WI-38 senescent human fibroblasts.

Journal: Experimental gerontology20040301

Title: Degradation of AP2 during reticulocyte maturation enhances binding of hsc70 and Alix to a common site on TFR for sorting into exosomes.

Journal: Traffic (Copenhagen, Denmark)20040301

Title: Vif overcomes the innate antiviral activity of APOBEC3G by promoting its degradation in the ubiquitin-proteasome pathway.

Journal: The Journal of biological chemistry20040227

Title: Differential effects of Parkinson's disease-associated mutations on stability and folding of DJ-1.

Journal: The Journal of biological chemistry20040220

Title: Glucocorticoids regulate mRNA levels for subunits of the 19 S regulatory complex of the 26 S proteasome in fast-twitch skeletal muscles.

Journal: The Biochemical journal20040215

Title: Sensitivity of proteasome to its inhibitors increases during cAMP-induced differentiation of neuroblastoma cells in culture and causes decreased viability.

Journal: Cancer letters20040210

Title: Proteasome inhibition and aggregation in Parkinson's disease: a comparative study in untransfected and transfected cells.

Journal: Journal of neurochemistry20040201

Title: Overexpression of torsinA in PC12 cells protects against toxicity.

Journal: Journal of neurochemistry20040201

Title: Long-term up-regulation of eNOS and improvement of endothelial function by inhibition of the ubiquitin-proteasome pathway.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20040201

Title: Laminar shear stress up-regulates inducible nitric oxide synthase in the endothelium.

Journal: Hypertension research : official journal of the Japanese Society of Hypertension20040201

Title: p53-mediated mitochondrial dysfunction by proteasome inhibition in dopaminergic SH-SY5Y cells.

Journal: Neuroscience letters20040116

Title: Estradiol binding to maxi-K channels induces their down-regulation via proteasomal degradation.

Journal: The Journal of biological chemistry20040109

Title: Temporal control of NF-kappaB activation by ERK differentially regulates interleukin-1beta-induced gene expression.

Journal: The Journal of biological chemistry20040109

Title: The ubiquitin-proteasome pathway is required for the function of the viral VP16 transcriptional activation domain.

Journal: FEBS letters20040102

Title: Induction of murine NAD(P)H:quinone oxidoreductase by 2,3,7,8-tetrachlorodibenzo-p-dioxin requires the CNC (cap 'n' collar) basic leucine zipper transcription factor Nrf2 (nuclear factor erythroid 2-related factor 2): cross-interaction between AhR (aryl hydrocarbon receptor) and Nrf2 signal transduction.

Journal: The Biochemical journal20040101

Title: The role of [beta]-transducin repeat-containing protein ([beta]-TrCP) in the regulation of NF-[kappa]B in vascular smooth muscle cells.

Journal: Arteriosclerosis, thrombosis, and vascular biology20040101

Title: Parkin is recruited into aggresomes in a stress-specific manner: over-expression of parkin reduces aggresome formation but can be dissociated from parkin's effect on neuronal survival.

Journal: Human molecular genetics20040101

Title: Activation of the Raf-1/MEK/Erk kinase pathway by a novel Cdc25 inhibitor in human prostate cancer cells.

Journal: The Prostate20040101

Title: Altered proteasome function and subunit composition in aged muscle.

Journal: Archives of biochemistry and biophysics20040101

Title: Interferon-gamma induces apoptosis of lens alphaTN4-1 cells and proteasome inhibition has an antiapoptotic effect.

Journal: Investigative ophthalmology & visual science20040101

Title: Degradation of poly(A)-binding protein in apoptotic cells and linkage to translation regulation.

Journal: Apoptosis : an international journal on programmed cell death20040101

Title: Contribution of the constitutive and inducible degradation of Smad3 by the ubiquitin-proteasome pathway to transforming growth factor-beta signaling.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20040101

Title: The proteosome inhibitor MG132 attenuates retinoic acid receptor trans-activation and enhances trans-repression of nuclear factor kappaB. Potential relevance to chemo-preventive interventions with retinoids.

Journal: Molecular cancer20040101

Title: Proteasome inhibition induces a senescence-like phenotype in primary human fibroblasts cultures.

Journal: Biogerontology20040101

Title: Inhibition of the proteasome reduces transfer-induced diabetes in nonobese diabetic mice.

Journal: Scandinavian journal of immunology20040101

Title: Proteasome inhibitors: their effects on arachidonic acid release from cells in culture and arachidonic acid metabolism in rat liver cells.

Journal: BMC pharmacology20040101

Title: Induction of heat shock protein 70 (Hsp70) by proteasome inhibitor MG 132 protects articular chondrocytes from cellular death in vitro and in vivo.

Journal: Biorheology20040101

Title: [Effect of synthetic proteasomal inhibitor MG132 on dynamics of EGF-receptor complexes endocytosis in A431 cells].

Journal: Tsitologiia20040101

Title: The co-repressor hairless protects RORalpha orphan nuclear receptor from proteasome-mediated degradation.

Journal: The Journal of biological chemistry20031226

Title: Induction of cIAP-2 in human colon cancer cells through PKC delta/NF-kappa B.

Journal: The Journal of biological chemistry20031219

Title: Redistribution of intracellular oxygen in hypoxia by nitric oxide: effect on HIF1alpha.

Journal: Science (New York, N.Y.)20031212

Title: Coordinate expression of the alpha and beta subunits of heterotrimeric G proteins involves regulation of protein degradation in CHO cells.

Journal: FEBS letters20031204

Title: Ubiquitin-mediated proteasome activity is required for agonist-induced endocytosis of GluRs.

Journal: Current biology : CB20031202

Title: The ubiquitin-vacuolar protein sorting system is selectively required during entry of influenza virus into host cells.

Journal: Traffic (Copenhagen, Denmark)20031201

Title: SHP-1 suppresses cancer cell growth by promoting degradation of JAK kinases.

Journal: Journal of cellular biochemistry20031201

Title: Cysteine proteases and cell differentiation: excystment of the ciliated protist Sterkiella histriomuscorum.

Journal: Eukaryotic cell20031201

Title: Proteasome inhibitors: a novel tool to suppress human cytomegalovirus replication and virus-induced immune modulation.

Journal: Antiviral therapy20031201

Title: NF-kappaB inhibition restores sensitivity to Fas-mediated apoptosis in lymphoma cell lines.

Journal: Annals of the New York Academy of Sciences20031201

Title: Homogeneous assays for cellular protein degradation using beta-galactosidase complementation: NF-kappaB/IkappaB pathway signaling.

Journal: Assay and drug development technologies20031201

Title: Upregulation of the truncated basic hair keratin 1(hHb1-DeltaN) in carcinoma cells by Epstein-Barr virus (EBV).

Journal: International journal of cancer20031120

Title: Generation of fertile cloned rats by regulating oocyte activation.

Journal: Science (New York, N.Y.)20031114

Title: Effect of MG132, a proteasome inhibitor, on the expression of growth related oncogene protein-alpha in human umbilical vein endothelial cells.

Journal: Cytokine20031107

Title: Lipopolysaccharide and proinflammatory cytokines stimulate interleukin-6 expression in C2C12 myoblasts: role of the Jun NH2-terminal kinase.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20031101

Title: Metabolic stabilization of MAP kinase phosphatase-2 in senescence of human fibroblasts.

Journal: Experimental cell research20031101

Title: Effects of TNFalpha on expression of ICAM-1 in human airway epithelial cells in vitro: oxidant-mediated pathways and transcription factors.

Journal: Free radical biology & medicine20031101

Title: Inhibition of proteasome function leads to NF-kappaB-independent IL-8 expression in human hepatocytes.

Journal: Hepatology (Baltimore, Md.)20031101

Title: Lipopolysaccharide activates nuclear factor-kappaB through toll-like receptors and related molecules in cultured biliary epithelial cells.

Journal: Laboratory investigation; a journal of technical methods and pathology20031101

Title: Cks1 is degraded via the ubiquitin-proteasome pathway in a cell cycle-dependent manner.

Journal: Genes to cells : devoted to molecular & cellular mechanisms20031101

Title: Chlamydia pneumoniae induces the expression of inhibitor of apoptosis 2 (c-IAP2) in a human monocytic cell line by an NF-kappaB-dependent pathway.

Journal: International journal of medical microbiology : IJMM20031101

Title: Ubiquitination regulates PSD-95 degradation and AMPA receptor surface expression.

Journal: Neuron20031030

Title: Proteasome inhibition induces nuclear translocation of the dioxin receptor through an Sp1 and protein kinase C-dependent pathway.

Journal: Journal of molecular biology20031017

Title: Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-kappaB-dependent process.

Journal: Oncogene20031016

Title: The meiosis I-to-meiosis II transition in mouse oocytes requires separase activity.

Journal: Current biology : CB20031014

Title: Overexpression of PREP-1 in F9 teratocarcinoma cells leads to a functionally relevant increase of PBX-2 by preventing its degradation.

Journal: The Journal of biological chemistry20031003

Title: Regulation of follitropin receptor cell surface residency by the ubiquitin-proteasome pathway.

Journal: Endocrinology20031001

Title: Proteasome inhibitor (MG-132) treatment of mdx mice rescues the expression and membrane localization of dystrophin and dystrophin-associated proteins.

Journal: The American journal of pathology20031001

Title: Proteasome inhibition stabilizes tau inclusions in oligodendroglial cells that occur after treatment with okadaic acid.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20031001

Title: Blockade of Hsp27 overcomes Bortezomib/proteasome inhibitor PS-341 resistance in lymphoma cells.

Journal: Cancer research20031001

Title: Proteasome-mediated degradation of RNase L in response to phorbol-12-myristate-13-acetate (PMA) treatment of mouse L929 cells.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20031001

Title: Regulation of nuclear factor-kappaB in intestinal epithelial cells in a cell model of inflammation.

Journal: Mediators of inflammation20031001

Title: Degradation of retinoid X receptor alpha by TPA through proteasome pathway in gastric cancer cells.

Journal: World journal of gastroenterology20030915

Title: Copper modulates the degradation of copper chaperone for Cu,Zn superoxide dismutase by the 26 S proteosome.

Journal: The Journal of biological chemistry20030912

Title: Involvement of the proteasome in activation of endothelial nitric oxide synthase.

Journal: Life sciences20030912

Title: Protein kinase C inhibition induces DNA fragmentation in COLO 205 cells which is blocked by cysteine protease inhibition but not mediated through caspase-3.

Journal: Experimental cell research20030910

Title: Conditions associated with ER dysfunction activate homer 1a expression.

Journal: Journal of neurochemistry20030901

Title: A novel structural class of potent inhibitors of NF-kappa B activation: structure-activity relationships and biological effects of 6-aminoquinazoline derivatives.

Journal: Bioorganic & medicinal chemistry20030901

Title: Sulindac metabolites induce caspase- and proteasome-dependent degradation of beta-catenin protein in human colon cancer cells.

Journal: Molecular cancer therapeutics20030901

Title: Transforming growth factor-beta inhibition of proteasomal activity: a potential mechanism of growth arrest.

Journal: American journal of physiology. Cell physiology20030801

Title: Phosphorylation of threonine 10 on CKBBP1/SAG/ROC2/Rbx2 by protein kinase CKII promotes the degradation of IkappaBalpha and p27Kip1.

Journal: The Journal of biological chemistry20030801

Title: Induction of apoptosis in human osteosarcoma Saos-2 cells by the proteasome inhibitor MG132 and the protective effect of pRb.

Journal: Cell death and differentiation20030801

Title: A transgenic mouse model of the ubiquitin/proteasome system.

Journal: Nature biotechnology20030801

Title: The proteasome as a lipopolysaccharide-binding protein in macrophages: differential effects of proteasome inhibition on lipopolysaccharide-induced signaling events.

Journal: Journal of immunology (Baltimore, Md. : 1950)20030801

Title: Thiopental inhibits tumor necrosis factor alpha-induced activation of nuclear factor kappaB through suppression of kappaB kinase activity.

Journal: Anesthesiology20030801

Title: Stimulation of protein degradation by low pH in L6G8C5 skeletal muscle cells is independent of apoptosis but dependent on differentiation state.

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association20030801

Title: Proteomic analysis of ubiquitin-proteasome effects: insight into the function of eukaryotic initiation factor 5A.

Journal: Oncogene20030731

Title: Development of an in vitro assay for the proteolytic processing of the CDP/Cux transcription factor.

Journal: Journal of biochemistry and molecular biology20030731

Title: Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.

Journal: The Journal of biological chemistry20030725

Title: Involvement of the ubiquitin-proteasome system in the early stages of wallerian degeneration.

Journal: Neuron20030717

Title: BCL6 overexpression prevents increase in reactive oxygen species and inhibits apoptosis induced by chemotherapeutic reagents in B-cell lymphoma cells.

Journal: Oncogene20030717

Title: UVB irradiation reduces the half-life and transactivation potential of the human papillomavirus 16 E2 protein.

Journal: Oncogene20030717

Title: The C-terminal T peptide of acetylcholinesterase enhances degradation of unassembled active subunits through the ERAD pathway.

Journal: The EMBO journal20030715

Title: Interleukin-3, -5, and granulocyte macrophage colony-stimulating factor-induced adhesion molecule expression on eosinophils by p38 mitogen-activated protein kinase and nuclear factor-[kappa] B.

Journal: American journal of respiratory cell and molecular biology20030701

Title: Specific ubiquitin-conjugating enzymes promote degradation of specific nuclear receptor coactivators.

Journal: Molecular endocrinology (Baltimore, Md.)20030701

Title: Recovery of gap junctional intercellular communication after phorbol ester treatment requires proteasomal degradation of protein kinase C.

Journal: Carcinogenesis20030701

Title: Characterization of the expression of the hepatitis C virus F protein.

Journal: The Journal of general virology20030701

Title: Imaging 26S proteasome activity and inhibition in living mice.

Journal: Nature medicine20030701

Title: Platelet-type 12-lipoxygenase activates NF-kappaB in prostate cancer cells.

Journal: Prostaglandins & other lipid mediators20030701

Title: The cleavage product deltaPML-RARalpha contributes to all-trans retinoic acid-mediated differentiation in acute promyelocytic leukemia cells.

Journal: Oncogene20030626

Title: Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation.

Journal: Genes & development20030615

Title: Suppression of cytochrome P450 3A protein levels by proteasome inhibitors.

Journal: The Journal of pharmacology and experimental therapeutics20030601

Title: Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells.

Journal: Hepatology (Baltimore, Md.)20030601

Title: Vanadate and rapamycin synergistically enhance insulin-stimulated glucose uptake.

Journal: Metabolism: clinical and experimental20030601

Title: Inhibition of the proteasome by lactacystin enhances oligodendroglial cell differentiation.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience20030601

Title: Cellular senescence in human keratinocytes: unchanged proteolytic capacity and increased protein load.

Journal: Experimental gerontology20030601

Title: Apoptosis meets proteasome, an invaluable therapeutic target of anticancer drugs.

Journal: The Italian journal of biochemistry20030601

Title: Activation of Nrf2 and accumulation of ubiquitinated A170 by arsenic in osteoblasts.

Journal: Biochemical and biophysical research communications20030530

Title: Early degradation of paternal mitochondria in domestic pig (Sus scrofa) is prevented by selective proteasomal inhibitors lactacystin and MG132.

Journal: Biology of reproduction20030501

Title: Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substrates.

Journal: The international journal of biochemistry & cell biology20030501

Title: Diminished NF-kappaB activation and PDGF-B expression in glomerular endothelial cells subjected to chronic shear stress.

Journal: Microvascular research20030501

Title: Concomitant differentiation and partial proteasome inhibition trigger apoptosis in neuroblastoma cells.

Journal: Journal of neuro-oncology20030501

Title: Distinct protein kinase C isoforms mediate regulation of vascular endothelial growth factor expression by A2A adenosine receptor activation and phorbol esters in pheochromocytoma PC12 cells.

Journal: The Journal of biological chemistry20030425

Title: p62 overexpression in breast tumors and regulation by prostate-derived Ets factor in breast cancer cells.

Journal: Oncogene20030417

Title: P53 facilitates degradation of human T-cell leukaemia virus type I Tax-binding protein through a proteasome-dependent pathway.

Journal: The Journal of general virology20030401

Title: NF-kappaB regulates intestinal epithelial cell and bile salt-induced migration after injury.

Journal: Annals of surgery20030401

Title: Oxidized low-density lipoprotein sensitizes human vascular smooth muscle cells to FAS (CD95)-mediated apoptosis.

Journal: Clinical and experimental pharmacology & physiology20030401

Title: Cacospongionolide B suppresses the expression of inflammatory enzymes and tumour necrosis factor-alpha by inhibiting nuclear factor-kappa B activation.

Journal: British journal of pharmacology20030401

Title: Stress-induced release of HSC70 from human tumors.

Journal: Cellular immunology20030401

Title: Bio-effectiveness of Tat-catalase conjugate: a potential tool for the identification of H2O2-dependent cellular signal transduction pathways.

Journal: Biochemical and biophysical research communications20030328

Title: Methyl-CpG-DNA binding proteins in human prostate cancer: expression of CXXC sequence containing MBD1 and repression of MBD2 and MeCP2.

Journal: Biochemical and biophysical research communications20030321

Title: Dissecting temporal and spatial control of cytokinesis with a myosin II Inhibitor.

Journal: Science (New York, N.Y.)20030314

Title: Presenilin-dependent gamma-secretase activity mediates the intramembranous cleavage of CD44.

Journal: Oncogene20030313

Title: C/EBP family transcription factors are degraded by the proteasome but stabilized by forming dimer.

Journal: Oncogene20030306

Title: The human herpes virus 8-encoded viral FLICE inhibitory protein protects against growth factor withdrawal-induced apoptosis via NF-kappa B activation.

Journal: Blood20030301

Title: RNA polymerase II stalled on a DNA template during transcription elongation is ubiquitinated and the ubiquitination facilitates displacement of the elongation complex.

Journal: International journal of oncology20030301

Title: Functional analysis of murine aryl hydrocarbon (AH) receptors defective in nuclear import: impact on AH receptor degradation and gene regulation.

Journal: Molecular pharmacology20030301

Title: Facilitation of fas mediated apoptosis of human chondrocytes by the proteasome inhibitor and actinomycin D.

Journal: The Journal of rheumatology20030301

Title: The aryl hydrocarbon receptor mediates degradation of estrogen receptor alpha through activation of proteasomes.

Journal: Molecular and cellular biology20030301

Title: Inhibition of the NF-kappaB signaling pathway mediates the anti-inflammatory effects of petrosaspongiolide M.

Journal: Biochemical pharmacology20030301

Title: Inducible p27(Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors.

Journal: Cell death and differentiation20030301

Title: EphA2 overexpression correlates with poor prognosis in esophageal squamous cell carcinoma.

Journal: International journal of cancer20030220

Title: Activation of multiple caspases and modification of cell surface fas (CD95) in proteasome inhibitor-induced apoptosis of rat natural killer cells.

Journal: Journal of cellular biochemistry20030215

Title: Increased protein stability as a mechanism that enhances Nrf2-mediated transcriptional activation of the antioxidant response element. Degradation of Nrf2 by the 26 S proteasome.

Journal: The Journal of biological chemistry20030214

Title: Regulation of the dephosphorylation of Stat6. Participation of Tyr-713 in the interleukin-4 receptor alpha, the tyrosine phosphatase SHP-1, and the proteasome.

Journal: The Journal of biological chemistry20030207

Title: C-terminal Hsp-interacting protein slows androgen receptor synthesis and reduces its rate of degradation.

Journal: Archives of biochemistry and biophysics20030201

Title: Tumour necrosis factor-alpha-induced expression of intercellular adhesion molecule-1 on human eosinophilic leukaemia EoL-1 cells is mediated by the activation of nuclear factor-kappaB pathway.

Journal: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology20030201

Title: Enhancement of TNF-alpha-mediated cell death in vascular smooth muscle cells through cytochrome c-independent pathway by the proteasome inhibitor.

Journal: FEBS letters20030130

Title: Phosphorylation of connexin 43 acts as a stimuli for proteasome-dependent degradation of the protein in lens epithelial cells.

Journal: Molecular vision20030130

Title: Degradation of transcription factor Nrf2 via the ubiquitin-proteasome pathway and stabilization by cadmium.

Journal: The Journal of biological chemistry20030124

Title: Endoproteolytic activity of the proteasome.

Journal: Science (New York, N.Y.)20030117

Title: Interleukin-6 induces thermotolerance in cultured Caco-2 cells independent of the heat shock response.

Journal: Cytokine20030107

Title: p53 and MDM2 are regulated by PI-3-kinases on multiple levels under stress induced by UV radiation and proteasome dysfunction.

Journal: Cellular signalling20030101

Title: Increased proteasome-dependent degradation of estrogen receptor-alpha by TGF-beta1 in breast cancer cell lines.

Journal: Journal of cellular biochemistry20030101

Title: The highly conserved Ndc80 complex is required for kinetochore assembly, chromosome congression, and spindle checkpoint activity.

Journal: Genes & development20030101

Title: Antineoplastic therapy in colorectal cancer through proteasome inhibition.

Journal: The American surgeon20030101

Title: Ubiquitinylation and proteasome-dependent degradation of the phosphoinositide-specific phospholipase C gamma 1 in A-431 cells.

Journal: Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections20030101

Title: [Effect of EGF on ubiquitination and proteasome-dependent degradation of phospholipase C gamma1 in A431 cells].

Journal: Tsitologiia20030101

Title: Involvement of proteasome in the dynamic assembly of the androgen receptor transcription complex.

Journal: The Journal of biological chemistry20021213

Title: TGF-beta induced G(1) cell cycle arrest requires the activity of the proteasome pathway. Transforming growth factor.

Journal: Experimental cell research20021210

Title: Regulation of the 14-3-3-binding protein p39 by growth factors and nutrients in rat PC12 pheochromocytoma cells.

Journal: The Biochemical journal20021201

Title: Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation.

Journal: Gastroenterology20021201

Title: Attenuation of glucocorticoid signaling through targeted degradation of p300 via the 26S proteasome pathway.

Journal: Molecular endocrinology (Baltimore, Md.)20021201

Title: TNF-alpha protects human primary articular chondrocytes from nitric oxide-induced apoptosis via nuclear factor-kappaB.

Journal: Laboratory investigation; a journal of technical methods and pathology20021201

Title: Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol.

Journal: Science (New York, N.Y.)20021129

Title: Neurotoxicity and neurodegeneration when PrP accumulates in the cytosol.

Journal: Science (New York, N.Y.)20021129

Title: Removal of Pex3p is an important initial stage in selective peroxisome degradation in Hansenula polymorpha.

Journal: The Journal of biological chemistry20021108

Title: A novel phenoxazine derivative suppresses surface IgM expression in DT40 B cell line.

Journal: British journal of pharmacology20021101

Title: Human chorionic gonadotropin (HCG) activates monocytes to produce interleukin-8 via a different pathway from luteinizing hormone/HCG receptor system.

Journal: The Journal of clinical endocrinology and metabolism20021101

Title: Sustained activation of N-WASP through phosphorylation is essential for neurite extension.

Journal: Developmental cell20021101

Title: The life cycle of the steroidogenic acute regulatory (StAR) protein: from transcription through proteolysis.

Journal: Endocrine research20021101

Title: Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop.

Journal: Science (New York, N.Y.)20021025

Title: Regulation of Egr-1 by association with the proteasome component C8.

Journal: Biochimica et biophysica acta20021021

Title: Jak2 is involved in c-Myc induction by Bcr-Abl.

Journal: Oncogene20021017

Title: Orthovanadate decreases the leptin content in isolated mouse fat pads via proteasome activation.

Journal: Archives of biochemistry and biophysics20021015

Title: Transcriptional activation of the human stress-inducible transcriptional repressor ATF3 gene promoter by p53.

Journal: Biochemical and biophysical research communications20021011

Title: Ligand-dependent and independent modulation of aryl hydrocarbon receptor localization, degradation, and gene regulation.

Journal: Molecular pharmacology20021001

Title: Apoptosis induced in hepatoblastoma HepG2 cells by the proteasome inhibitor MG132 is associated with hydrogen peroxide production, expression of Bcl-XS and activation of caspase-3.

Journal: International journal of oncology20021001

Title: Hypoxia induces proteasome-dependent degradation of estrogen receptor alpha in ZR-75 breast cancer cells.

Journal: Molecular endocrinology (Baltimore, Md.)20021001

Title: Synphilin-1 degradation by the ubiquitin-proteasome pathway and effects on cell survival.

Journal: Journal of neurochemistry20021001

Title: Accelerated degradation of mislocalized UDP-glucuronosyltransferase family 1 (UGT1) proteins in Gunn rat hepatocytes.

Journal: Archives of biochemistry and biophysics20020915

Title: Proteasomal activity modulates TGF-ss signaling in a gene-specific manner.

Journal: FEBS letters20020911

Title: Proteasome inhibitors regulate tyrosine phosphorylation of IRS-1 and insulin signaling in adipocytes.

Journal: Biochemical and biophysical research communications20020906

Title: Glucocorticoid-mediated attenuation of the hsp70 response in trout hepatocytes involves the proteasome.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20020901

Title: Lipopolysaccharide regulates proinflammatory cytokine expression in mouse myoblasts and skeletal muscle.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20020901

Title: c-Cbl is a negative regulator of GH-stimulated STAT5-mediated transcription.

Journal: Endocrinology20020901

Title: Glucocorticoid receptors in hippocampal neurons that do not engage proteasomes escape from hormone-dependent down-regulation but maintain transactivation activity.

Journal: Molecular endocrinology (Baltimore, Md.)20020901

Title: Proteasome inhibitors induce apoptosis in growth hormone- and prolactin-secreting rat pituitary tumor cells.

Journal: The Journal of endocrinology20020901

Title: Proteasome-dependent downregulation of p21(Waf1/Cip1) induced by reactive oxygen species.

Journal: Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research20020901

Title: Proteasome inhibitors stimulate activator protein-1 pathway via reactive oxygen species production.

Journal: FEBS letters20020828

Title: Induction and superinduction of 2,3,7,8-tetrachlorodibenzo-rho-dioxin-inducible poly(ADP-ribose) polymerase: role of the aryl hydrocarbon receptor/aryl hydrocarbon receptor nuclear translocator transcription activation domains and a labile transcription repressor.

Journal: Archives of biochemistry and biophysics20020815

Title: Proteasome inhibitors stimulate interleukin-8 expression via Ras and apoptosis signal-regulating kinase-dependent extracellular signal-related kinase and c-Jun N-terminal kinase activation.

Journal: American journal of respiratory cell and molecular biology20020801

Title: Nuclear factor-kappa B is required for tumor necrosis factor-alpha-induced manganese superoxide dismutase expression in human endometrial stromal cells.

Journal: The Journal of clinical endocrinology and metabolism20020801

Title: TNF-alpha-mediated apoptosis in chondrocytes sensitized by MG132 or actinomycin D.

Journal: Biochemical and biophysical research communications20020726

Title: E3 ubiquitin ligase that recognizes sugar chains.

Journal: Nature20020725

Title: Cellular steady-state levels of 'high risk' but not 'low risk' human papillomavirus (HPV) E6 proteins are increased by inhibition of proteasome-dependent degradation independent of their p53- and E6AP-binding capabilities.

Journal: Virology20020720

Title: Expression of kinin B(1) receptor in fresh or cultured rabbit aortic smooth muscle: role of NF-kappa B.

Journal: American journal of physiology. Heart and circulatory physiology20020701

Title: NF-kappaB p50 and p52 expression is not required for RANK-expressing osteoclast progenitor formation but is essential for RANK- and cytokine-mediated osteoclastogenesis.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research20020701

Title: The effect of proteasome inhibitors on mammalian erythroid terminal differentiation.

Journal: Experimental hematology20020701

Title: Cell adhesion protects c-Raf-1 against ubiquitin-dependent degradation by the proteasome.

Journal: Biochemical and biophysical research communications20020628

Title: Localization and roles in fertilization of sperm proteasomes in the ascidian Halocynthia roretzi.

Journal: Molecular reproduction and development20020601

Title: The role of the proteasome in apoptosis induced by anthracycline anticancer agents.

Journal: International journal of oncology20020601

Title: Further pharmacological evidence of nuclear factor-kappa B pathway involvement in bradykinin B1 receptor-sensitized responses in human umbilical vein.

Journal: The Journal of pharmacology and experimental therapeutics20020601

Title: Interleukin-17 stimulates the expression of interleukin-8, growth-related oncogene-alpha, and granulocyte-colony-stimulating factor by human airway epithelial cells.

Journal: American journal of respiratory cell and molecular biology20020601

Title: Human papillomavirus E6-induced degradation of E6TP1 is mediated by E6AP ubiquitin ligase.

Journal: Cancer research20020601

Title: The expression of decorin in human ovarian tumors.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research20020601

Title: Activation of p38 mitogen-activated protein kinase and nuclear factor-kappaB in tumour necrosis factor-induced eotaxin release of human eosinophils.

Journal: Clinical and experimental immunology20020601

Title: Proteasome inhibitor MG-132 enhances the expression of interleukin-6 in human umbilical vein endothelial cells: Involvement of MAP/ERK kinase.

Journal: Immunology and cell biology20020601

Title: Cell-cycle dependent dynamic change of 26S proteasome distribution in tobacco BY-2 cells.

Journal: Plant & cell physiology20020601

Title: Proteasome inhibitors in the treatment of B-cell malignancies.

Journal: Clinical lymphoma20020601

Title: A gene trap Dissociation insertion line, associated with a RING-H2 finger gene, shows tissue specific and developmental regulated expression of the gene in Arabidopsis.

Journal: Gene20020515

Title: Ammonia induces MK-801-sensitive nitration and phosphorylation of protein tyrosine residues in rat astrocytes.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology20020501

Title: Divergence of apoptosis-inducing and preventing signals in bacteria-faced macrophages through myeloid differentiation factor 88 and IL-1 receptor-associated kinase members.

Journal: Journal of immunology (Baltimore, Md. : 1950)20020501

Title: Geldanamycin induces degradation of hypoxia-inducible factor 1alpha protein via the proteosome pathway in prostate cancer cells.

Journal: Cancer research20020501

Title: Nuclear factor (NF)-kappa B blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial cells.

Journal: Biochemical and biophysical research communications20020426

Title: Inhibition of mu and delta opioid receptor ligand binding by the peptide aldehyde protease inhibitor, leupeptin.

Journal: Regulatory peptides20020415

Title: Proteasome inhibitors induce heat shock response and increase IL-6 expression in human intestinal epithelial cells.

Journal: American journal of physiology. Regulatory, integrative and comparative physiology20020401

Title: Inhibition of proteasomes induces accumulation, phosphorylation, and recruitment of HSP27 and alphaB-crystallin to aggresomes.

Journal: Journal of biochemistry20020401

Title: PDTC and Mg132, inhibitors of NF-kappaB, block endotoxin induced vasodilation of isolated rat skeletal muscle arterioles.

Journal: Shock (Augusta, Ga.)20020401

Title: A proteasome inhibitor confers cardioprotection.

Journal: Cardiovascular research20020401

Title: Hypoxia enhances the expression of plasminogen activator inhibitor-1 in human lung cancer cells, EBC-1.

Journal: The Tohoku journal of experimental medicine20020401

Title: Nuclear factor-kappa B-independent regulation of lipopolysaccharide-mediated interleukin-6 biosynthesis.

Journal: Biochemical and biophysical research communications20020308

Title: Inhibition of the ubiquitin-proteasome pathway induces differential heat-shock protein response in cardiomyocytes and renders early cardiac protection.

Journal: Biochemical and biophysical research communications20020301

Title: Both ALG-2 and peflin, penta-EF-hand (PEF) proteins, are stabilized by dimerization through their fifth EF-hand regions.

Journal: Archives of biochemistry and biophysics20020301

Title: A cycloheximide-sensitive factor regulates TCDD-induced degradation of the aryl hydrocarbon receptor.

Journal: Chemosphere20020301

Title: A possible intermediate step during apoptotic execution.

Journal: Human cell20020301

Title: The susceptibility to Fas-induced apoptosis in normal enterocytes is regulated on the level of cIAP1 and 2.

Journal: Biochemical and biophysical research communications20020201

Title: Inhibition of nuclear factor-kappaB activation un-masks the ability of TNF-alpha to induce human eosinophil apoptosis.

Journal: European journal of immunology20020201

Title: Translocation of small heat shock proteins to the actin cytoskeleton upon proteasomal inhibition.

Journal: Journal of molecular and cellular cardiology20020201

Title: Intracellular mechanisms mediating the inhibition of apoB-containing lipoprotein synthesis and secretion in HepG2 cells by avasimibe (CI-1011), a novel acyl-coenzyme A: cholesterol acyltransferase (ACAT) inhibitor.

Journal: Biochemical pharmacology20020201

Title: Ubiquitin, proteasome, and restenosis: a brave new world for cardiovascular research.

Journal: Circulation20020129

Title: Ubiquitin-proteasome pathway as a new target for the prevention of restenosis.

Journal: Circulation20020129

Title: Proteasome inhibitors activate the transcription factors C/EBP-beta and delta in human intestinal epithelial cells.

Journal: Biochemical and biophysical research communications20020111

Title: Arsenite stabilizes IkappaBalpha and prevents NF-kappaB activation in IL-1 beta-stimulated Caco-2 cells independent of the heat shock response.

Journal: Journal of cellular biochemistry20020101

Title: Evidence for a pre-restriction point Cdk3 activity.

Journal: Journal of cellular biochemistry20020101

Title: The PEST sequence does not contribute to the stability of the cystic fibrosis transmembrane conductance regulator.

Journal: BMC biochemistry20020101

Title: Induction of histone acetylation and inhibition of growth of mouse erythroleukemia cells by S-allylmercaptocysteine.

Journal: Nutrition and cancer20020101

Title: Effects of proteasome inhibitors on the synaptic localization of Vesl-1S/Homer-1a proteins.

Journal: Brain research. Molecular brain research20011230

Title: Transfected synphilin-1 forms cytoplasmic inclusions in HEK293 cells.

Journal: Brain research. Molecular brain research20011216

Title: Combined modulation of the mesangial machinery for monocyte recruitment by inhibition of NF-kappaB.

Journal: American journal of physiology. Cell physiology20011201

Title: Possible new role for NF-kappaB in the resolution of inflammation.

Journal: Nature medicine20011201

Title: Regulation of functional nuclear pore size in fibroblasts.

Journal: Journal of cell science20011201

Title: 6-Hydroxydopamine increases ubiquitin-conjugates and protein degradation: implications for the pathogenesis of Parkinson's disease.

Journal: Cellular and molecular neurobiology20011201

Title: The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes.

Journal: The Journal of biological chemistry20011130

Title: Role of ATP in influenza virus budding.

Journal: Virology20011125

Title: Redundancy of mammalian proteasome beta subunit function during endoplasmic reticulum associated degradation.

Journal: Biochemistry20011106

Title: Nuclear factor-kappa B augments beta(2)-adrenergic receptor expression in human airway epithelial cells.

Journal: American journal of physiology. Lung cellular and molecular physiology20011101

Title: Regulation of rheumatoid synoviocyte proliferation by endogenous p53 induction.

Journal: Clinical and experimental immunology20011101

Title: Leukemia stem cells and constitutive activation of NF-kappaB.

Journal: Blood20011015

Title: Nuclear factor-kappaB is constitutively activated in primitive human acute myelogenous leukemia cells.

Journal: Blood20011015

Title: Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha.

Journal: Biochemical pharmacology20011001

Title: Regulation and distribution of MAdCAM-1 in endothelial cells in vitro.

Journal: American journal of physiology. Cell physiology20011001

Title: Proteasome-mediated degradation of BRCA1 protein in MCF-7 human breast cancer cells.

Journal: International journal of oncology20011001

Title: Proteasome inhibitors differentially affect heat shock protein response in cancer cells.

Journal: International journal of molecular medicine20011001

Title: Enhanced proteolysis of IkappaBalpha and IkappaBbeta proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: a potential mechanism of NF-kappaB activation.

Journal: Journal of neurovirology20011001

Title: Inflammatory gene transcription in human astrocytes exposed to hypoxia: roles of the nuclear factor-kappaB and autocrine stimulation.

Journal: Journal of neuroimmunology20011001

Title: Molecular pathways that modify tumor radiation response.

Journal: American journal of clinical oncology20011001

Title: Proteasome activity is critical for the cAMP-induced differentiation of neuroblastoma cells.

Journal: Cellular and molecular neurobiology20011001

Title: The deubiquitinating enzyme DUB-2 prolongs cytokine-induced signal transducers and activators of transcription activation and suppresses apoptosis following cytokine withdrawal.

Journal: Blood20010915

Title: Proteasome inhibitor enhances growth hormone-binding protein release.

Journal: Molecular and cellular endocrinology20010901

Title: Proteasome inhibitor-induced apoptosis of B-chronic lymphocytic leukaemia cells involves cytochrome c release and caspase activation, accompanied by formation of an approximately 700 kDa Apaf-1 containing apoptosome complex.

Journal: Leukemia20010901

Title: Role of the proteasome in the regulation of fetal fibronectin secretion in human placenta.

Journal: Annals of the New York Academy of Sciences20010901

Title: Proteasome inhibitors and immunosuppressive drugs promote the cleavage of eIF4GI and eIF4GII by caspase-8-independent mechanisms in Jurkat T cell lines.

Journal: FEBS letters20010817

Title: Different effects of p14ARF on the levels of ubiquitinated p53 and Mdm2 in vivo.

Journal: Oncogene20010816

Title: Inhibition of proteasome function induced apoptosis in gastric cancer.

Journal: International journal of cancer20010815

Title: The human type 2 iodothyronine deiodinase is a selenoprotein highly expressed in a mesothelioma cell line.

Journal: The Journal of biological chemistry20010810

Title: Both Rb and E7 are regulated by the ubiquitin proteasome pathway in HPV-containing cervical tumor cells.

Journal: Oncogene20010802

Title: Removal of oxidatively damaged proteins from lens cells by the ubiquitin-proteasome pathway.

Journal: Experimental eye research20010801

Title: Unexpected transcriptional induction of monocyte chemoattractant protein 1 by proteasome inhibition: involvement of the c-Jun N-terminal kinase-activator protein 1 pathway.

Journal: Journal of immunology (Baltimore, Md. : 1950)20010801

Title: Effects of arachidonic and docosahexaenoic acids on secretion and degradation of bile salt-dependent lipase in AR4-2J cells.

Journal: Journal of lipid research20010801

Title: Nuclear factor-kappa B is upregulated in colorectal cancer.

Journal: Surgery20010801

Title: Reversion of temperature-sensitive mutation by inhibition of proteasome-mediated degradation of mutated D123 protein.

Journal: Cell structure and function20010801

Title: Liver alcohol dehydrogenase is degraded by the ubiquitin-proteasome pathway.

Journal: Biochemical and biophysical research communications20010720

Title: Heat-induced proteasomic degradation of HSF1 in serum-starved human fibroblasts aging in vitro.

Journal: Experimental cell research20010715

Title: PKCdelta-dependent deubiquitination and stabilization of Gadd45 in A431 cells overexposed to EGF.

Journal: Biochemical and biophysical research communications20010713

Title: Tumor necrosis factor alpha induces expression of genes for matrix degradation in human chondrocyte-like HCS-2/8 cells through activation of NF-kappaB: abrogation of the tumor necrosis factor alpha effect by proteasome inhibitors.

Journal: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research20010701

Title: Inhibition of proteasome activity strongly affects kiwifruit pollen germination. Involvement of the ubiquitin/proteasome pathway as a major regulator.

Journal: Plant physiology20010701

Title: Trehalose accumulation during cellular stress protects cells and cellular proteins from damage by oxygen radicals.

Journal: The Journal of biological chemistry20010629

Title: Secretase targets for Alzheimer's disease: identification and therapeutic potential.

Journal: Journal of medicinal chemistry20010621

Title: Cyclic AMP-independent activation of protein kinase A by vasoactive peptides.

Journal: The Journal of biological chemistry20010615

Title: Involvement of proteasomes in gene induction by interferon and double-stranded RNA.

Journal: Cytokine20010607

Title: Involvement of all-trans-retinoic acid in the breakdown of retinoic acid receptors alpha and gamma through proteasomes in MCF-7 human breast cancer cells.

Journal: Biochemical pharmacology20010601

Title: Differential degradation of the three fibrinogen chains by proteasomes: involvement of Sec61p and cytosolic Hsp70.

Journal: Archives of biochemistry and biophysics20010601

Title: Effect of NF-kappa B Inhibition on TNF-alpha-induced apoptosis and downstream pathways in cardiomyocytes.

Journal: Journal of molecular and cellular cardiology20010601

Title: The effect of hydrogen peroxide on the cyclin D expression in fibroblasts.

Journal: Cellular and molecular life sciences : CMLS20010601

Title: Potential role of nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase in apoptosis and oxidative stress.

Journal: Journal of cell science20010501

Title: Accumulation of soluble and nucleolar-associated p53 proteins following cellular stress.

Journal: Journal of cell science20010501

Title: Differentiation-dependent sensitivity to cell death induced in the developing retina by inhibitors of the ubiquitin-proteasome proteolytic pathway.

Journal: The European journal of neuroscience20010501

Title: Biochemical characterization of the gamma-secretase activity that produces beta-amyloid peptides.

Journal: Biochemistry20010424

Title: Enac degradation in A6 cells by the ubiquitin-proteosome proteolytic pathway.

Journal: The Journal of biological chemistry20010420

Title: IFNalpha sensitizes ME-180 human cervical cancer cells to TNFalpha-induced apoptosis by inhibiting cytoprotective NF-kappaB activation.

Journal: FEBS letters20010420

Title: Role of proteasomal degradation in the cell cycle-dependent regulation of DNA topoisomerase IIalpha expression.

Journal: Biochemical pharmacology20010401

Title: Characterization of NF-kappaB expression in Hodgkin's disease: inhibition of constitutively expressed NF-kappaB results in spontaneous caspase-independent apoptosis in Hodgkin and Reed-Sternberg cells.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc20010401

Title: Relationship of fiber surface iron and active oxygen species to expression of procollagen, PDGF-A, and TGF-beta(1) in tracheal explants exposed to amosite asbestos.

Journal: American journal of respiratory cell and molecular biology20010401

Title: Specific inhibitors prevent proteolytic degradation of recombinant proteins expressed in High Five cells.

Journal: BioTechniques20010401

Title: Roles of NF-kappaB and 26 S proteasome in apoptotic cell death induced by topoisomerase I and II poisons in human nonsmall cell lung carcinoma.

Journal: The Journal of biological chemistry20010316

Title: Agonist-specific regulation of monocyte chemoattractant protein-1 expression by cyclooxygenase metabolites in hepatic stellate cells.

Journal: Hepatology (Baltimore, Md.)20010301

Title: Pro-caspase-3 overexpression sensitises ovarian cancer cells to proteasome inhibitors.

Journal: Cell death and differentiation20010301

Title: Impairment of bile salt-dependent lipase secretion in AR4-2J rat pancreatic cells induces its degradation by the proteasome.

Journal: Biochimica et biophysica acta20010226

Title: Proteasome inhibitors sensitize human vascular smooth muscle cells to Fas (CD95)-mediated death.

Journal: Biochemical and biophysical research communications20010223

Title: Ubiquitin-mediated degradation of hepatitis C virus core protein is regulated by processing at its carboxyl terminus.

Journal: Virology20010215

Title: Inhibition of NF-kappaB sensitizes human pancreatic carcinoma cells to apoptosis induced by etoposide (VP16) or doxorubicin.

Journal: Oncogene20010215

Title: The protease inhibitor, MG132, blocks maturation of the amyloid precursor protein Swedish mutant preventing cleavage by beta-Secretase.

Journal: The Journal of biological chemistry20010209

Title: The proteasome inhibitor MG132 promotes accumulation of the steroidogenic acute regulatory protein (StAR) and steroidogenesis.

Journal: FEBS letters20010209

Title: Proteasome inhibitor induces nucleolar translocation of Epstein-Barr virus-encoded EBNA-5.

Journal: The Journal of general virology20010201

Title: Double-stranded RNA-dependent protein kinase is not required for double-stranded RNA-induced nitric oxide synthase expression or nuclear factor-kappaB activation by islets.

Journal: Diabetes20010201

Title: Relationship between NF-kappaB and trypsinogen activation in rat pancreas after supramaximal caerulein stimulation.

Journal: Biochemical and biophysical research communications20010112

Title: The proteasome regulates receptor-mediated endocytosis of interleukin-2.

Journal: The Journal of biological chemistry20010105

Title: Expression of the NF-kappa B target gene IEX-1 (p22/PRG1) does not prevent cell death but instead triggers apoptosis in Hela cells.

Journal: Oncogene20010104

Title: FRAP reveals that mobility of oestrogen receptor-alpha is ligand- and proteasome-dependent.

Journal: Nature cell biology20010101

Title: Blockade NF-kappaB activation prohibits TNF-alpha-induced cyclooxygenase-2 gene expression in ED27 trophoblast-like cells.

Journal: Placenta20010101

Title: Inhibition of NF-kappa B with proteasome inhibitors enhances apoptosis in human lung adenocarcinoma cells in vitro.

Journal: Anticancer research20010101

Title: JNK phosphorylates the HSF1 transcriptional activation domain: role of JNK in the regulation of the heat shock response.

Journal: Journal of cellular biochemistry20010101

Title: Potential of the proteasomal inhibitor MG-132 as an anticancer agent, alone and in combination.

Journal: Anticancer research20010101

Title: Differential mRNA expression of prostaglandin receptor subtypes in macrophage activation.

Journal: Prostaglandins, leukotrienes, and essential fatty acids20010101

Title: Proteasome inhibition interferes with gag polyprotein processing, release, and maturation of HIV-1 and HIV-2.

Journal: Proceedings of the National Academy of Sciences of the United States of America20001121

Title: Crosstalk between estrogen receptor alpha and the aryl hydrocarbon receptor in breast cancer cells involves unidirectional activation of proteasomes.

Journal: FEBS letters20000728

Title: Proteasome inhibitors block intracellular growth and replication of Toxoplasma gondii.

Journal: Parasitology20000701

Title: Polycyclic aromatic hydrocarbon carcinogens increase ubiquitination of p21 protein after the stabilization of p53 and the expression of p21.

Journal: American journal of respiratory cell and molecular biology20000601

Title: Superinduction of CYP1A1 gene expression. Regulation of 2,3,7, 8-tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximide.

Journal: The Journal of biological chemistry20000428

Title: 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced degradation of aryl hydrocarbon receptor (AhR) by the ubiquitin-proteasome pathway. Role of the transcription activaton and DNA binding of AhR.

Journal: The Journal of biological chemistry20000324

Title: Protease inhibitors: current status and future prospects.

Journal: Journal of medicinal chemistry20000210

Title: Bioflavonoid quercetin inhibits interleukin-1-induced transcriptional expression of monocyte chemoattractant protein-1 in glomerular cells via suppression of nuclear factor-kappaB.

Journal: Journal of the American Society of Nephrology : JASN19991101

Title: The apoptotic effects and synergistic interaction of sodium butyrate and MG132 in human retinoblastoma Y79 cells.

Journal: Cancer research19991101

Title: Aryl hydrocarbon receptor imported into the nucleus following ligand binding is rapidly degraded via the cytosplasmic proteasome following nuclear export.

Journal: The Journal of biological chemistry19991001

Title: Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K(+)-ATPase through proteasomal and endo-/lysosomal proteolytic pathways.

Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology19991001

Title: Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids.

Journal: Bioorganic & medicinal chemistry letters19980217

Title: Purification and characterization of a Z-Leu-Leu-Leu-MCA degrading protease expected to regulate neurite formation: a novel catalytic activity in proteasome.

Journal: Biochemical and biophysical research communications19931115

Title: Phosphorylation of activation function-1 regulates proteasome-dependent nuclear mobility and E6-associated protein ubiquitin ligase recruitment to the estrogen receptor beta.

Journal: Molecular endocrinology (Baltimore, Md.)

Title: RelB/NF-κB2 regulates corticotropin-releasing hormone in the human placenta.

Journal: Molecular endocrinology (Baltimore, Md.)

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