Home Imidazoles 1848-69-7
1848-69-7,MFCD02671066
Catalog No.:AA0074PY

1848-69-7 | 1-Phenylimidazolidin-2-one

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250mg
98%
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$145.00   $102.00
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1g
98%
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$394.00   $276.00
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5g
98%
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$1,175.00   $823.00
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10g
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$1,733.00   $1,213.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0074PY
Chemical Name:
1-Phenylimidazolidin-2-one
CAS Number:
1848-69-7
Molecular Formula:
C9H10N2O
Molecular Weight:
162.1885
MDL Number:
MFCD02671066
SMILES:
O=C1NCCN1c1ccccc1
NSC Number:
80633
Properties
Computed Properties
 
Complexity:
175  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
12  
Hydrogen Bond Acceptor Count:
1  
Hydrogen Bond Donor Count:
1  
Rotatable Bond Count:
1  
XLogP3:
0.9  

Downstream Synthesis Route

[1]Patent:US2518264,1946,

64-17-5   
<i>N</i>-(2-bromo-ethyl)-<i>N</i>-phenyl-urea 
  141-52-6    1848-69-7 

[1]Experientia,1957,vol.13,p.183

[1]JournaloftheAmericanChemicalSociety,1950,vol.72,p.3659

[1]JournalofMedicinalChemistry,2011,vol.54,p.4559-4580

[2]Patent:WO2011/100840,2011,A1.Locationinpatent:Page/Pagecolumn25;84-85

[3]EuropeanJournalofMedicinalChemistry,2011,vol.46,p.5327-5342

[4]ChemischeBerichte,1895,vol.28,p.2933

[5]Bioorganicandmedicinalchemistryletters,1999,vol.9,p.749-754

[6]JournalofMedicinalChemistry,2017,vol.60,p.4963-4982

[7]BioorganicandMedicinalChemistry,2018,vol.26,p.5045-5052

[1]Patent:US2517750,1943,

Literature

Title: Substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonamides as antimitotics. Antiproliferative, antiangiogenic and antitumoral activity, and quantitative structure-activity relationships.

Journal: European journal of medicinal chemistry 20111101

Title: Design, synthesis, biological evaluation, and structure-activity relationships of substituted phenyl 4-(2-oxoimidazolidin-1-yl)benzenesulfonates as new tubulin inhibitors mimicking combretastatin A-4.

Journal: Journal of medicinal chemistry 20110714

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

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SDS
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