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Home Other Building Blocks 177582-20-6
177582-20-6,MFCD05663448
Catalog No.:AA0078GP

177582-20-6 | S-4-Methoxyltrityl-L-cysteine

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Purity
Availability
Price(USD)
Quantity
  
1g
≥ 97% (HPLC)
in stock  
$72.00   $51.00
- +
5g
≥ 97% (HPLC)
in stock  
$195.00   $137.00
- +
25g
≥ 97% (HPLC)
in stock  
$618.00   $433.00
- +
  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA0078GP
Chemical Name:
S-4-Methoxyltrityl-L-cysteine
CAS Number:
177582-20-6
Molecular Formula:
C23H23NO3S
Molecular Weight:
393.4986
MDL Number:
MFCD05663448
SMILES:
OCc1ccc(cc1)C(c1ccccc1)(c1ccccc1)SC[C@@H](C(=O)O)N
Properties
Computed Properties
 
Complexity:
462  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
5  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  
XLogP3:
1.9  

Literature

Title: Triphenylbutanamines: kinesin spindle protein inhibitors with in vivo antitumor activity.

Journal: Journal of medicinal chemistry 20120223

Title: Synthesis and characterization of tritylthioethanamine derivatives with potent KSP inhibitory activity.

Journal: Bioorganic & medicinal chemistry 20110915

Title: Structure-activity relationship and multidrug resistance study of new S-trityl-L-cysteine derivatives as inhibitors of Eg5.

Journal: Journal of medicinal chemistry 20110324

Title: A potent chemotherapeutic strategy in prostate cancer: S-(methoxytrityl)-L-cysteine, a novel Eg5 inhibitor.

Journal: Asian journal of andrology 20110301

Title: Bis(hetero)aryl derivatives as unique kinesin spindle protein inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20090215

Title: Structure-activity relationship of S-trityl-L-cysteine analogues as inhibitors of the human mitotic kinesin Eg5.

Journal: Journal of medicinal chemistry 20080313

Title: Synthesis and biological evaluation of L-cysteine derivatives as mitotic kinesin Eg5 inhibitors.

Journal: Bioorganic & medicinal chemistry letters 20070715

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SDS
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Tags:177582-20-6 Molecular Formula|177582-20-6 MDL|177582-20-6 SMILES|177582-20-6 S-4-Methoxyltrityl-L-cysteine