112885-42-4,MFCD01666680
Catalog No.:AA0078N2

112885-42-4 | Mosapride citrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1g
98%(HPLC)powder
in stock  
$40.00   $28.00
- +
5g
98%(HPLC)powder
in stock  
$91.00   $64.00
- +
10g
98%(HPLC)powder
in stock  
$158.00   $110.00
- +
25g
98%(HPLC)powder
in stock  
$313.00   $219.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
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Technical Information
Catalog Number:
AA0078N2
Chemical Name:
Mosapride citrate
CAS Number:
112885-42-4
Molecular Formula:
C27H33ClFN3O10
Molecular Weight:
614.0164
MDL Number:
MFCD01666680
SMILES:
OC(=O)CC(C(=O)O)(CC(=O)O)O.CCOc1cc(N)c(cc1C(=O)NCC1OCCN(C1)Cc1ccc(cc1)F)Cl
Properties
Computed Properties
 
Complexity:
749  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
0  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
42  
Hydrogen Bond Acceptor Count:
13  
Hydrogen Bond Donor Count:
6  
Isotope Atom Count:
0  
Rotatable Bond Count:
12  
Undefined Atom Stereocenter Count:
1  
Undefined Bond Stereocenter Count:
0  

Literature

Title: Metabolic and toxicological considerations for the latest drugs used to treat irritable bowel syndrome.

Journal: Expert opinion on drug metabolism & toxicology 20130401

Title: Effect of mosapride on prednisolone-induced gastric mucosal injury and gastric-emptying disorder in dog.

Journal: The Journal of veterinary medical science 20120901

Title: Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.

Journal: Pharmacological research 20120901

Title: Pharmacokinetic and bioavailability studies of 5 mg mosapride tablets in healthy Korean volunteers.

Journal: International journal of clinical pharmacology and therapeutics 20120701

Title: Effect of mosapride citrate on gastric emptying in interferon-induced gastroparesis.

Journal: Digestive diseases and sciences 20120601

Title: The effects of 5-HT4 receptor agonist, mosapride citrate, on visceral hypersensitivity in a rat model.

Journal: Digestive diseases and sciences 20120601

Title: Efficacy of mosapride citrate with polyethylene glycol solution for colonoscopy preparation.

Journal: World journal of gastroenterology 20120528

Title: A prospective randomized trial of mosapride vs. placebo in constipation-predominant irritable bowel syndrome.

Journal: The American journal of gastroenterology 20120501

Title: Comparison of PPIs and H2-receptor antagonists plus prokinetics for dysmotility-like dyspepsia.

Journal: World journal of gastroenterology 20120407

Title: Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anastomosis in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20120315

Title: Stability-indicating methods for the determination of mosapride citrate in the presence of its degradation products according to ICH guidelines.

Journal: Drug testing and analysis 20120201

Title: Influence of gastric acid on gastric emptying and gastric distension-induced pain response in rats--effects of famotidine and mosapride.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20120201

Title: Large-scale randomized clinical study on functional dyspepsia treatment with mosapride or teprenone: Japan Mosapride Mega-Study (JMMS).

Journal: Journal of gastroenterology and hepatology 20120101

Title: Oral hypertonic electrolyte-glucose/mosapride complex solution for resuscitation of burn shock in dogs.

Journal: Journal of burn care & research : official publication of the American Burn Association 20120101

Title: Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH.

Journal: BMC gastroenterology 20120101

Title: Efficacy of omeprazole, famotidine, mosapride and teprenone in patients with upper gastrointestinal symptoms: an omeprazole-controlled randomized study (J-FOCUS).

Journal: BMC gastroenterology 20120101

Title: Prokinetic effect of the 5-HT4R agonist mosapride on canine gastric motility.

Journal: The Journal of veterinary medical science 20111201

Title: Characterization and optimization of orodispersible mosapride film formulations.

Journal: AAPS PharmSciTech 20111201

Title: Relative bioavailability of a 5 mg mosapride/10 mg rabeprazole fixed dose combination tablet versus separate single tablets in healthy volunteers: a single-dose randomized open-label crossover study.

Journal: Current medical research and opinion 20111101

Title: Formulation optimization of solid dispersion of mosapride hydrochloride.

Journal: Archives of pharmacal research 20110901

Title: Mosapride citrate improves postoperative ileus of patients with colectomy.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 20110801

Title: Effect of 5-HT4 receptor agonist mosapride citrate on rectosigmoid sensorimotor function in patients with irritable bowel syndrome.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110801

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry 20110714

Title: Effects of mosapride on esophageal secondary peristalsis in humans.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20110701

Title: Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus.

Journal: Gut 20110501

Title: Addition of prokinetic therapy to a PPI in reflux diseases.

Journal: Alimentary pharmacology & therapeutics 20110401

Title: Simotang enhances gastrointestinal motility, motilin and cholecystokinin expression in chronically stressed mice.

Journal: World journal of gastroenterology 20110328

Title: In vitro enhanced differentiation of neural networks in ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation.

Journal: Biochemical and biophysical research communications 20110325

Title: Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride.

Journal: The Journal of pharmacology and experimental therapeutics 20110301

Title: Effect of chronic pain on morphine-induced respiratory depression in mice.

Journal: Neuroscience 20110203

Title: Proton pump inhibitor versus prokinetic therapy in patients with functional dyspepsia: is therapeutic response predicted by Rome III subgroups?

Journal: Journal of gastroenterology 20110201

Title: Randomised clinical trial: efficacy of the addition of a prokinetic, mosapride citrate, to omeprazole in the treatment of patients with non-erosive reflux disease - a double-blind, placebo-controlled study.

Journal: Alimentary pharmacology & therapeutics 20110201

Title: Effects of mosapride citrate, a 5-HT4-receptor agonist, on gastric distension-induced visceromotor response in conscious rats.

Journal: Journal of pharmacological sciences 20110101

Title: Pharmacokinetics and bioequivalence study of two mosapride citrate formulations after single-dose administration in healthy Chinese male volunteers.

Journal: Arzneimittel-Forschung 20110101

Title: Are symptomatic changes in irritable bowel syndrome correlated with the capsule endoscopy transit time? A pilot study using the 5-HT4 receptor agonist mosapride.

Journal: Hepato-gastroenterology 20110101

Title: Usefulness of a slow nutrient drinking test for evaluating gastric perception and accommodation.

Journal: Digestion 20110101

Title: Ultrasonographic evaluation of vincristine-induced gastric hypomotility and the prokinetic effect of mosapride in dogs.

Journal: Journal of veterinary internal medicine 20110101

Title: Efficacy of mosapride citrate in proximal gastric accommodation and gastrointestinal motility in healthy volunteers: a double-blind placebo-controlled ultrasonographic study.

Journal: Journal of gastroenterology 20101201

Title: Development of a novel combination tablet containing trimebutine maleate and mosapride citrate for the treatment of functional dyspepsia.

Journal: International journal of pharmaceutics 20101115

Title: Pharmacokinetics of the gastroprokinetic agent mosapride citrate after single oral administration in horses.

Journal: The Journal of veterinary medical science 20100801

Title: Mosapride as an adjunct to lansoprazole for symptom relief of reflux oesophagitis.

Journal: British journal of clinical pharmacology 20100801

Title: A 5-HT(4)-receptor activation-induced neural plasticity enhances in vivo reconstructs of enteric nerve circuit insult.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20100701

Title: Effects of mosapride on esophageal functions and gastroesophageal reflux.

Journal: Journal of gastroenterology and hepatology 20100601

Title: Antiangiogenic effect of a selective 5-HT4 receptor agonist.

Journal: The Journal of surgical research 20100401

Title: The prokinetic effect of mosapride citrate combined with omeprazole therapy improves clinical symptoms and gastric emptying in PPI-resistant NERD patients with delayed gastric emptying.

Journal: Journal of gastroenterology 20100401

Title: HPLC-fluorescence assay for measuring mosapride in small volumes of rat plasma.

Journal: Biomedical chromatography : BMC 20100301

Title: The effect of mosapride (5HT-4 receptor agonist) on insulin sensitivity and GLUT4 translocation.

Journal: Diabetes research and clinical practice 20100301

Title: The 5-HT4 receptor agonist mosapride attenuates NSAID-induced gastric mucosal damage.

Journal: Journal of gastroenterology 20100201

Title: The effect of mosapride citrate on constipation in patients with diabetes.

Journal: Diabetes research and clinical practice 20100101

Title: Endoscopic evaluation of gastric emptying and effect of mosapride citrate on gastric emptying.

Journal: Yonsei medical journal 20100101

Title: Protracted cisplatin-induced vomiting responding to mosapride.

Journal: Indian journal of cancer 20100101

Title: [Effect of electro-acupuncture in treating morphine sulfate caused constipation in tumor patients].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20091001

Title: Characterization of metabolic profile of mosapride citrate in rat and identification of two new metabolites: Mosapride N-oxide and morpholine ring-opened mosapride by UPLC-ESI-MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis 20090815

Title: Effect of mosapride citrate hydrate on the colon cleansing action of polyethylene glycol electrolyte lavage solution (PEG-ELS) in guinea pigs.

Journal: Journal of pharmacological sciences 20090801

Title: Assessment of gastric motor function by cine magnetic resonance imaging.

Journal: Journal of gastroenterology and hepatology 20090801

Title: [Effect of prokinetic agents on the electrical activity of stomach and duodenum in rats].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences 20090701

Title: Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy.

Journal: Journal of veterinary science 20090601

Title: [Clinical observation on transcutaneous electrical acupoint stimulation for treatment of functional dyspepsia].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion 20090601

Title: [Study on colonic motility and efficacy analysis in patients with slow-transit constipation treated with self-formulated Xingchang Decoction].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine 20090501

Title: Effects of mosapride citrate, metoclopramide hydrochloride, lidocaine hydrochloride, and cisapride citrate on equine gastric emptying, small intestinal and caecal motility.

Journal: Research in veterinary science 20090401

Title: Mosapride and postoperative ileus.

Journal: Diseases of the colon and rectum 20090401

Title: The plasticity of the defecation reflex pathway in the enteric nervous system of guinea pigs.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20090201

Title: Rapid effect of mosapride citrate, 5-HT4 receptor agonist, on fasting blood glucose in Type 2 diabetes patients.

Journal: Journal of diabetes and its complications 20090101

Title: Impaired gastric motility and its relationship to reflux symptoms in patients with nonerosive gastroesophageal reflux disease.

Journal: Journal of gastroenterology 20090101

Title: Early effects of oral administration of lafutidine with mosapride compared with lafutidine alone on intragastric pH values.

Journal: BMC gastroenterology 20090101

Title: Indirect spectrofluorimetric determination of mosapride citrate in pharmaceutical formulations.

Journal: Acta poloniae pharmaceutica 20090101

Title: Effect of mosapride on recovery of intestinal motility after hand-assisted laparoscopic colectomy for carcinoma.

Journal: Diseases of the colon and rectum 20081101

Title: Choledochoscope manometry about different drugs on the Sphincter of Oddi.

Journal: World journal of gastroenterology 20081014

Title: Validation of 13C-acetic acid breath test by measuring effects of loperamide, morphine, mosapride, and itopride on gastric emptying in mice.

Journal: Biological & pharmaceutical bulletin 20081001

Title: Frequency scale symptoms for gastroesophageal reflux disease (Frequency Scale for Symptoms of GERD) predicts need for addition of prokinetics to proton pump inhibitor therapy.

Journal: Journal of gastroenterology and hepatology 20080801

Title: Multiple system atrophy and impaired gallbladder emptying.

Journal: Movement disorders : official journal of the Movement Disorder Society 20080715

Title: The in vivo gastrointestinal activity of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080701

Title: The in vitro pharmacological profile of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.

Journal: Naunyn-Schmiedeberg's archives of pharmacology 20080701

Title: The prokinetic effect of mosapride citrate on horse gastric emptying rates.

Journal: The Journal of veterinary medical science 20080601

Title: A new possibility for repairing the anal dysfunction by promoting regeneration of the reflex pathways in the enteric nervous system.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20080401

Title: The effect of mosapride citrate on proximal and distal colonic motor function in the guinea-pig in vitro.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society 20080201

Title: High-performance liquid chromatography and thin-layer chromatography for the simultaneous quantitation of rabeprazole and mosapride in pharmaceutical products.

Journal: Journal of chromatographic science 20080101

Title: Mosapride in gastrointestinal disorders.

Journal: Drugs 20080101

Title: Efficacy of prokinetic agents in improving bowel preparation for colonoscopy.

Journal: Digestion 20080101

Title: Effects of mosapride citrate on patients after vagal nerve, lower esophageal sphincter, and pyloric sphincter-preserving nearly total gastrectomy reconstructed by jejunal J pouch interposition, and postoperative quality of life.

Journal: Hepato-gastroenterology 20080101

Title: Role of ion channel modifiers in reversal of morphine-induced gastrointestinal inertia by prokinetic agents in mice.

Journal: Indian journal of experimental biology 20080101

Title: Prokinetics influence the pharmacokinetics of rabeprazole.

Journal: Digestion 20080101

Title: Liquid chromatography-tandem mass spectrometric method for determination of mosapride citrate in equine tissues.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20071015

Title: Effect of mosapride on gastrointestinal transit time and diagnostic yield of capsule endoscopy.

Journal: Journal of gastroenterology and hepatology 20071001

Title: Treatment of functional dyspepsia with serotonin agonists: a meta-analysis of randomized controlled trials.

Journal: Journal of gastroenterology and hepatology 20071001

Title: The 5-HT(4) agonists cisapride, mosapride, and CJ-033466, a Novel potent compound, exhibit different human ether-a-go-go-related gene (hERG)-blocking activities.

Journal: Journal of pharmacological sciences 20071001

Title: [Determination of mosapride in human plasma by high performance liquid chromatography tandem mass spectrometry].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20070801

Title: Quantification of pseudoephedrine in human plasma by LC-MS/MS using mosapride as internal standard.

Journal: Biomedical chromatography : BMC 20070301

Title: Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia.

Journal: Journal of gastroenterology and hepatology 20070301

Title: Quantification of fexofenadine in human plasma by liquid chromatography coupled to electrospray tandem mass spectrometry using mosapride as internal standard.

Journal: Biomedical chromatography : BMC 20070201

Title: Mosapride citrate prolongs survival in stroke patients with gastrostomy.

Journal: Journal of the American Geriatrics Society 20070101

Title: Enhancement of the intrinsic defecation reflex by mosapride, a 5-HT4 agonist, in chronically lumbosacral denervated guinea pigs.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi 20061001

Title: [Serotonin 5- HT4 receptor agonist (mosapride citrate)].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20060801

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: The effect of mosapride on esophageal motility and bolus transit in asymptomatic volunteers.

Journal: Journal of clinical gastroenterology 20060401

Title: Enantioselective determination of a gastroprokinetic drug using amylose tris-(3,5-dimethylphenylcarbamate) as a stationary phase by HPLC.

Journal: Journal of pharmaceutical and biomedical analysis 20060213

Title: Effects of mosapride citrate on patients after vagal nerve preserving distal gastrectomy reconstructed by interposition of a jejunal J pouch with a jejunal conduit for early gastric cancer.

Journal: World journal of surgery 20060201

Title: Measurement of 5-HT4 receptor-mediated esophageal responses by digital sonomicrometry in the anesthetized rat.

Journal: Journal of pharmacological and toxicological methods 20060101

Title: Mosapride improves food intake, while not worsening glycemic control and obesity, in ob/ob obese mice with decreased gastric emptying.

Journal: Journal of diabetes and its complications 20060101

Title: Increased gastric motility during 5-HT4 agonist therapy reduces response fluctuations in Parkinson's disease.

Journal: Parkinsonism & related disorders 20051201

Title: Validation and application of a high-performance liquid chromatography--tandem mass spectrometry assay for mosapride in human plasma.

Journal: Biomedical chromatography : BMC 20050901

Title: The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression.

Journal: Clinical pharmacology and therapeutics 20050901

Title: A 5-HT4 agonist, mosapride, enhances intrinsic rectorectal and rectoanal reflexes after removal of extrinsic nerves in guinea pigs.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20050801

Title: Effects of mosapride, a 5-hydroxytryptamine 4 receptor agonist, on electrical activity of the small intestine and cecum in horses.

Journal: American journal of veterinary research 20050801

Title: Mosapride citrate, a novel 5-HT4 agonist and partial 5-HT3 antagonist, ameliorates constipation in parkinsonian patients.

Journal: Movement disorders : official journal of the Movement Disorder Society 20050601

Title: Usefulness of famotidine in functional dyspepsia patient treatment: comparison among prokinetic, acid suppression and antianxiety therapies.

Journal: Alimentary pharmacology & therapeutics 20050601

Title: Effects of famotidine, mosapride and tandospirone for treatment of functional dyspepsia.

Journal: Alimentary pharmacology & therapeutics 20050601

Title: New strategy of therapy for functional dyspepsia using famotidine, mosapride and amitriptyline.

Journal: Alimentary pharmacology & therapeutics 20050601

Title: Persistent cough following pulmonary resection: observational and empiric study of possible causes.

Journal: The Annals of thoracic surgery 20050101

Title: Randomised, double-blind, comparative study to evaluate the efficacy and safety of ganaton (itopride hydrochloride) and mosapride citrate in the management of functional dyspepsia.

Journal: Journal of the Indian Medical Association 20041201

Title: Development and validation of a liquid chromatographic method for determination of related-substances of mosapride citrate in bulk drugs and pharmaceuticals.

Journal: Journal of pharmaceutical and biomedical analysis 20041119

Title: [The effect of mosapride on quality of life in functional dyspepsia].

Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi 20040301

Title: [A randomized controlled Multi-center clinical trial on mosapride in the treatment of functional dyspepsia].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi 20040201

Title: [New preparation method for barium enema: efficacy and administration of oral intestinal lavage solution with gastrointestinal prokinetic agent].

Journal: Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica 20040101

Title: Comparison of efficacy of pantoprazole alone versus pantoprazole plus mosapride in therapy of gastroesophageal reflux disease: a randomized trial.

Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus 20040101

Title: The effect of mosapride on oesophageal motor function and acid reflux in patients with gastro-oesophageal reflux disease.

Journal: European journal of gastroenterology & hepatology 20031001

Title: Effect of mosapride on glycemic control and gastric emptying in type 2 diabetes mellitus patients with gastropathy.

Journal: Diabetes research and clinical practice 20030901

Title: Investigation into the effects of mosapride on motility of Guinea pig stomach, ileum, and colon.

Journal: Yonsei medical journal 20030830

Title: A 5-HT4 agonist mosapride enhances rectorectal and rectoanal reflexes in guinea pigs.

Journal: American journal of physiology. Gastrointestinal and liver physiology 20030801

Title: Application of LC-MS/MS for the identification of a polar impurity in mosapride, a gastroprokinetic drug.

Journal: Journal of pharmaceutical and biomedical analysis 20030601

Title: Relative efficacy of some prokinetic drugs in morphine-induced gastrointestinal transit delay in mice.

Journal: World journal of gastroenterology 20030415

Title: Drug interaction between mosapride and erythromycin without electrocardiographic changes.

Journal: Japanese heart journal 20030301

Title: Effect of temperature on the reversal in the retention order of the enantiomers of mosapride on Chiral-AGP.

Journal: Journal of biochemical and biophysical methods 20021231

Title: Effects of mosapride citrate, a 5-HT4 receptor agonist, on colonic motility in conscious guinea pigs.

Journal: Japanese journal of pharmacology 20021201

Title: A validated RP-HPLC method for the determination of mosapride citrate in bulk drug samples and pharmaceutical formulations.

Journal: Die Pharmazie 20021201

Title: The determination of mosapride citrate in bulk drug samples and pharmaceutical dosage forms using HPLC.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry 20021101

Title: [Reflux esophagitis].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020801

Title: 5-HT4 receptor enhances the propulsive power of the peristaltic reflex in the rat distal colon.

Journal: Autonomic neuroscience : basic & clinical 20020731

Title: Mosapride, a 5HT-4 receptor agonist, improves insulin sensitivity and glycaemic control in patients with Type II diabetes mellitus.

Journal: Diabetologia 20020601

Title: Dose finding study of mosapride in functional dyspepsia: a placebo-controlled, randomized study.

Journal: Alimentary pharmacology & therapeutics 20020501

Title: Drug-induced ventricular tachyarrhythmia in isolated rabbit hearts with atrioventricular block.

Journal: Pharmacology & toxicology 20020501

Title: [Prokinetics of gastrointestinal system; its newer aspects with regard to motillity stimulants].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20020201

Title: Teratogenicity of the I(Kr)-blocker cisapride: relation to embryonic cardiac arrhythmia.

Journal: Reproductive toxicology (Elmsford, N.Y.) 20020101

Title: Influence of mosapride citrate on gastric motility and autonomic nervous function: evaluation by spectral analyses of heart rate and blood pressure variabilities, and by electrogastrography.

Journal: Journal of gastroenterology 20020101

Title: Gastrointestinal prokinetic drugs have different affinity for the human cardiac human ether-à-gogo K(+) channel.

Journal: The Journal of pharmacology and experimental therapeutics 20011201

Title: Characteristics of fluvoxamine-induced nausea.

Journal: Psychiatry research 20011130

Title: Effects of mosapride citrate on human plasma levels of motilin, gastrin, somatostatin, and secretin.

Journal: Biological & pharmaceutical bulletin 20010901

Title: Effects of 5-HT(4) receptor agonists, cisapride and mosapride citrate on electrocardiogram in anaesthetized rats and guinea-pigs and conscious cats.

Journal: Pharmacology & toxicology 20010801

Title: Torsades de pointes ventricular tachycardia induced by mosapride and flecainide in the presence of hypokalemia.

Journal: Pacing and clinical electrophysiology : PACE 20010101

Title: The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate.

Journal: Drug metabolism and disposition: the biological fate of chemicals 20001001

Title: Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-67.

Title: Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68(7):981-91.

Title: Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate). Nihon Rinsho. 2006 Aug;64(8):1491-4.

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SDS
Tags:112885-42-4 Molecular Formula|112885-42-4 MDL|112885-42-4 SMILES|112885-42-4 Mosapride citrate
Catalog No.: AA0078N2
112885-42-4,MFCD01666680
112885-42-4 | Mosapride citrate
Pack Size: 1g
Purity: 98%(HPLC)powder
in stock
$40.00 $28.00
Pack Size: 5g
Purity: 98%(HPLC)powder
in stock
$91.00 $64.00
Pack Size: 10g
Purity: 98%(HPLC)powder
in stock
$158.00 $110.00
Pack Size: 25g
Purity: 98%(HPLC)powder
in stock
$313.00 $219.00
Quantity
- +
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Technical Information
Catalog Number: AA0078N2
Chemical Name: Mosapride citrate
CAS Number: 112885-42-4
Molecular Formula: C27H33ClFN3O10
Molecular Weight: 614.0164
MDL Number: MFCD01666680
SMILES: OC(=O)CC(C(=O)O)(CC(=O)O)O.CCOc1cc(N)c(cc1C(=O)NCC1OCCN(C1)Cc1ccc(cc1)F)Cl
Properties
Complexity: 749  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 0  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 42  
Hydrogen Bond Acceptor Count: 13  
Hydrogen Bond Donor Count: 6  
Isotope Atom Count: 0  
Rotatable Bond Count: 12  
Undefined Atom Stereocenter Count: 1  
Undefined Bond Stereocenter Count: 0  
Literature fold

Title: Metabolic and toxicological considerations for the latest drugs used to treat irritable bowel syndrome.

Journal: Expert opinion on drug metabolism & toxicology20130401

Title: Effect of mosapride on prednisolone-induced gastric mucosal injury and gastric-emptying disorder in dog.

Journal: The Journal of veterinary medical science20120901

Title: Dual role of serotonin in the pathogenesis of indomethacin-induced small intestinal ulceration: pro-ulcerogenic action via 5-HT3 receptors and anti-ulcerogenic action via 5-HT4 receptors.

Journal: Pharmacological research20120901

Title: Pharmacokinetic and bioavailability studies of 5 mg mosapride tablets in healthy Korean volunteers.

Journal: International journal of clinical pharmacology and therapeutics20120701

Title: Effect of mosapride citrate on gastric emptying in interferon-induced gastroparesis.

Journal: Digestive diseases and sciences20120601

Title: The effects of 5-HT4 receptor agonist, mosapride citrate, on visceral hypersensitivity in a rat model.

Journal: Digestive diseases and sciences20120601

Title: Efficacy of mosapride citrate with polyethylene glycol solution for colonoscopy preparation.

Journal: World journal of gastroenterology20120528

Title: A prospective randomized trial of mosapride vs. placebo in constipation-predominant irritable bowel syndrome.

Journal: The American journal of gastroenterology20120501

Title: Comparison of PPIs and H2-receptor antagonists plus prokinetics for dysmotility-like dyspepsia.

Journal: World journal of gastroenterology20120407

Title: Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anastomosis in rats.

Journal: American journal of physiology. Gastrointestinal and liver physiology20120315

Title: Stability-indicating methods for the determination of mosapride citrate in the presence of its degradation products according to ICH guidelines.

Journal: Drug testing and analysis20120201

Title: Influence of gastric acid on gastric emptying and gastric distension-induced pain response in rats--effects of famotidine and mosapride.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society20120201

Title: Large-scale randomized clinical study on functional dyspepsia treatment with mosapride or teprenone: Japan Mosapride Mega-Study (JMMS).

Journal: Journal of gastroenterology and hepatology20120101

Title: Oral hypertonic electrolyte-glucose/mosapride complex solution for resuscitation of burn shock in dogs.

Journal: Journal of burn care & research : official publication of the American Burn Association20120101

Title: Early effect of oral administration of omeprazole with mosapride as compared with those of omeprazole alone on the intragastric pH.

Journal: BMC gastroenterology20120101

Title: Efficacy of omeprazole, famotidine, mosapride and teprenone in patients with upper gastrointestinal symptoms: an omeprazole-controlled randomized study (J-FOCUS).

Journal: BMC gastroenterology20120101

Title: Prokinetic effect of the 5-HT4R agonist mosapride on canine gastric motility.

Journal: The Journal of veterinary medical science20111201

Title: Characterization and optimization of orodispersible mosapride film formulations.

Journal: AAPS PharmSciTech20111201

Title: Relative bioavailability of a 5 mg mosapride/10 mg rabeprazole fixed dose combination tablet versus separate single tablets in healthy volunteers: a single-dose randomized open-label crossover study.

Journal: Current medical research and opinion20111101

Title: Formulation optimization of solid dispersion of mosapride hydrochloride.

Journal: Archives of pharmacal research20110901

Title: Mosapride citrate improves postoperative ileus of patients with colectomy.

Journal: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract20110801

Title: Effect of 5-HT4 receptor agonist mosapride citrate on rectosigmoid sensorimotor function in patients with irritable bowel syndrome.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society20110801

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry20110714

Title: Effects of mosapride on esophageal secondary peristalsis in humans.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society20110701

Title: Neuronal stimulation with 5-hydroxytryptamine 4 receptor induces anti-inflammatory actions via α7nACh receptors on muscularis macrophages associated with postoperative ileus.

Journal: Gut20110501

Title: Addition of prokinetic therapy to a PPI in reflux diseases.

Journal: Alimentary pharmacology & therapeutics20110401

Title: Simotang enhances gastrointestinal motility, motilin and cholecystokinin expression in chronically stressed mice.

Journal: World journal of gastroenterology20110328

Title: In vitro enhanced differentiation of neural networks in ES gut-like organ from mouse ES cells by a 5-HT4-receptor activation.

Journal: Biochemical and biophysical research communications20110325

Title: Acotiamide hydrochloride (Z-338), a new selective acetylcholinesterase inhibitor, enhances gastric motility without prolonging QT interval in dogs: comparison with cisapride, itopride, and mosapride.

Journal: The Journal of pharmacology and experimental therapeutics20110301

Title: Effect of chronic pain on morphine-induced respiratory depression in mice.

Journal: Neuroscience20110203

Title: Proton pump inhibitor versus prokinetic therapy in patients with functional dyspepsia: is therapeutic response predicted by Rome III subgroups?

Journal: Journal of gastroenterology20110201

Title: Randomised clinical trial: efficacy of the addition of a prokinetic, mosapride citrate, to omeprazole in the treatment of patients with non-erosive reflux disease - a double-blind, placebo-controlled study.

Journal: Alimentary pharmacology & therapeutics20110201

Title: Effects of mosapride citrate, a 5-HT4-receptor agonist, on gastric distension-induced visceromotor response in conscious rats.

Journal: Journal of pharmacological sciences20110101

Title: Pharmacokinetics and bioequivalence study of two mosapride citrate formulations after single-dose administration in healthy Chinese male volunteers.

Journal: Arzneimittel-Forschung20110101

Title: Are symptomatic changes in irritable bowel syndrome correlated with the capsule endoscopy transit time? A pilot study using the 5-HT4 receptor agonist mosapride.

Journal: Hepato-gastroenterology20110101

Title: Usefulness of a slow nutrient drinking test for evaluating gastric perception and accommodation.

Journal: Digestion20110101

Title: Ultrasonographic evaluation of vincristine-induced gastric hypomotility and the prokinetic effect of mosapride in dogs.

Journal: Journal of veterinary internal medicine20110101

Title: Efficacy of mosapride citrate in proximal gastric accommodation and gastrointestinal motility in healthy volunteers: a double-blind placebo-controlled ultrasonographic study.

Journal: Journal of gastroenterology20101201

Title: Development of a novel combination tablet containing trimebutine maleate and mosapride citrate for the treatment of functional dyspepsia.

Journal: International journal of pharmaceutics20101115

Title: Pharmacokinetics of the gastroprokinetic agent mosapride citrate after single oral administration in horses.

Journal: The Journal of veterinary medical science20100801

Title: Mosapride as an adjunct to lansoprazole for symptom relief of reflux oesophagitis.

Journal: British journal of clinical pharmacology20100801

Title: A 5-HT(4)-receptor activation-induced neural plasticity enhances in vivo reconstructs of enteric nerve circuit insult.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society20100701

Title: Effects of mosapride on esophageal functions and gastroesophageal reflux.

Journal: Journal of gastroenterology and hepatology20100601

Title: Antiangiogenic effect of a selective 5-HT4 receptor agonist.

Journal: The Journal of surgical research20100401

Title: The prokinetic effect of mosapride citrate combined with omeprazole therapy improves clinical symptoms and gastric emptying in PPI-resistant NERD patients with delayed gastric emptying.

Journal: Journal of gastroenterology20100401

Title: HPLC-fluorescence assay for measuring mosapride in small volumes of rat plasma.

Journal: Biomedical chromatography : BMC20100301

Title: The effect of mosapride (5HT-4 receptor agonist) on insulin sensitivity and GLUT4 translocation.

Journal: Diabetes research and clinical practice20100301

Title: The 5-HT4 receptor agonist mosapride attenuates NSAID-induced gastric mucosal damage.

Journal: Journal of gastroenterology20100201

Title: The effect of mosapride citrate on constipation in patients with diabetes.

Journal: Diabetes research and clinical practice20100101

Title: Endoscopic evaluation of gastric emptying and effect of mosapride citrate on gastric emptying.

Journal: Yonsei medical journal20100101

Title: Protracted cisplatin-induced vomiting responding to mosapride.

Journal: Indian journal of cancer20100101

Title: [Effect of electro-acupuncture in treating morphine sulfate caused constipation in tumor patients].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20091001

Title: Characterization of metabolic profile of mosapride citrate in rat and identification of two new metabolites: Mosapride N-oxide and morpholine ring-opened mosapride by UPLC-ESI-MS/MS.

Journal: Journal of pharmaceutical and biomedical analysis20090815

Title: Effect of mosapride citrate hydrate on the colon cleansing action of polyethylene glycol electrolyte lavage solution (PEG-ELS) in guinea pigs.

Journal: Journal of pharmacological sciences20090801

Title: Assessment of gastric motor function by cine magnetic resonance imaging.

Journal: Journal of gastroenterology and hepatology20090801

Title: [Effect of prokinetic agents on the electrical activity of stomach and duodenum in rats].

Journal: Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences20090701

Title: Effects of mosapride on motility of the small intestine and caecum in normal horses after jejunocaecostomy.

Journal: Journal of veterinary science20090601

Title: [Clinical observation on transcutaneous electrical acupoint stimulation for treatment of functional dyspepsia].

Journal: Zhongguo zhen jiu = Chinese acupuncture & moxibustion20090601

Title: [Study on colonic motility and efficacy analysis in patients with slow-transit constipation treated with self-formulated Xingchang Decoction].

Journal: Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine20090501

Title: Effects of mosapride citrate, metoclopramide hydrochloride, lidocaine hydrochloride, and cisapride citrate on equine gastric emptying, small intestinal and caecal motility.

Journal: Research in veterinary science20090401

Title: Mosapride and postoperative ileus.

Journal: Diseases of the colon and rectum20090401

Title: The plasticity of the defecation reflex pathway in the enteric nervous system of guinea pigs.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi20090201

Title: Rapid effect of mosapride citrate, 5-HT4 receptor agonist, on fasting blood glucose in Type 2 diabetes patients.

Journal: Journal of diabetes and its complications20090101

Title: Impaired gastric motility and its relationship to reflux symptoms in patients with nonerosive gastroesophageal reflux disease.

Journal: Journal of gastroenterology20090101

Title: Early effects of oral administration of lafutidine with mosapride compared with lafutidine alone on intragastric pH values.

Journal: BMC gastroenterology20090101

Title: Indirect spectrofluorimetric determination of mosapride citrate in pharmaceutical formulations.

Journal: Acta poloniae pharmaceutica20090101

Title: Effect of mosapride on recovery of intestinal motility after hand-assisted laparoscopic colectomy for carcinoma.

Journal: Diseases of the colon and rectum20081101

Title: Choledochoscope manometry about different drugs on the Sphincter of Oddi.

Journal: World journal of gastroenterology20081014

Title: Validation of 13C-acetic acid breath test by measuring effects of loperamide, morphine, mosapride, and itopride on gastric emptying in mice.

Journal: Biological & pharmaceutical bulletin20081001

Title: Frequency scale symptoms for gastroesophageal reflux disease (Frequency Scale for Symptoms of GERD) predicts need for addition of prokinetics to proton pump inhibitor therapy.

Journal: Journal of gastroenterology and hepatology20080801

Title: Multiple system atrophy and impaired gallbladder emptying.

Journal: Movement disorders : official journal of the Movement Disorder Society20080715

Title: The in vivo gastrointestinal activity of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20080701

Title: The in vitro pharmacological profile of TD-5108, a selective 5-HT(4) receptor agonist with high intrinsic activity.

Journal: Naunyn-Schmiedeberg's archives of pharmacology20080701

Title: The prokinetic effect of mosapride citrate on horse gastric emptying rates.

Journal: The Journal of veterinary medical science20080601

Title: A new possibility for repairing the anal dysfunction by promoting regeneration of the reflex pathways in the enteric nervous system.

Journal: American journal of physiology. Gastrointestinal and liver physiology20080401

Title: The effect of mosapride citrate on proximal and distal colonic motor function in the guinea-pig in vitro.

Journal: Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society20080201

Title: High-performance liquid chromatography and thin-layer chromatography for the simultaneous quantitation of rabeprazole and mosapride in pharmaceutical products.

Journal: Journal of chromatographic science20080101

Title: Mosapride in gastrointestinal disorders.

Journal: Drugs20080101

Title: Efficacy of prokinetic agents in improving bowel preparation for colonoscopy.

Journal: Digestion20080101

Title: Effects of mosapride citrate on patients after vagal nerve, lower esophageal sphincter, and pyloric sphincter-preserving nearly total gastrectomy reconstructed by jejunal J pouch interposition, and postoperative quality of life.

Journal: Hepato-gastroenterology20080101

Title: Role of ion channel modifiers in reversal of morphine-induced gastrointestinal inertia by prokinetic agents in mice.

Journal: Indian journal of experimental biology20080101

Title: Prokinetics influence the pharmacokinetics of rabeprazole.

Journal: Digestion20080101

Title: Liquid chromatography-tandem mass spectrometric method for determination of mosapride citrate in equine tissues.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences20071015

Title: Effect of mosapride on gastrointestinal transit time and diagnostic yield of capsule endoscopy.

Journal: Journal of gastroenterology and hepatology20071001

Title: Treatment of functional dyspepsia with serotonin agonists: a meta-analysis of randomized controlled trials.

Journal: Journal of gastroenterology and hepatology20071001

Title: The 5-HT(4) agonists cisapride, mosapride, and CJ-033466, a Novel potent compound, exhibit different human ether-a-go-go-related gene (hERG)-blocking activities.

Journal: Journal of pharmacological sciences20071001

Title: [Determination of mosapride in human plasma by high performance liquid chromatography tandem mass spectrometry].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica20070801

Title: Quantification of pseudoephedrine in human plasma by LC-MS/MS using mosapride as internal standard.

Journal: Biomedical chromatography : BMC20070301

Title: Meta-analysis of the effects of prokinetic agents in patients with functional dyspepsia.

Journal: Journal of gastroenterology and hepatology20070301

Title: Quantification of fexofenadine in human plasma by liquid chromatography coupled to electrospray tandem mass spectrometry using mosapride as internal standard.

Journal: Biomedical chromatography : BMC20070201

Title: Mosapride citrate prolongs survival in stroke patients with gastrostomy.

Journal: Journal of the American Geriatrics Society20070101

Title: Enhancement of the intrinsic defecation reflex by mosapride, a 5-HT4 agonist, in chronically lumbosacral denervated guinea pigs.

Journal: Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi20061001

Title: [Serotonin 5- HT4 receptor agonist (mosapride citrate)].

Journal: Nihon rinsho. Japanese journal of clinical medicine20060801

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: The effect of mosapride on esophageal motility and bolus transit in asymptomatic volunteers.

Journal: Journal of clinical gastroenterology20060401

Title: Enantioselective determination of a gastroprokinetic drug using amylose tris-(3,5-dimethylphenylcarbamate) as a stationary phase by HPLC.

Journal: Journal of pharmaceutical and biomedical analysis20060213

Title: Effects of mosapride citrate on patients after vagal nerve preserving distal gastrectomy reconstructed by interposition of a jejunal J pouch with a jejunal conduit for early gastric cancer.

Journal: World journal of surgery20060201

Title: Measurement of 5-HT4 receptor-mediated esophageal responses by digital sonomicrometry in the anesthetized rat.

Journal: Journal of pharmacological and toxicological methods20060101

Title: Mosapride improves food intake, while not worsening glycemic control and obesity, in ob/ob obese mice with decreased gastric emptying.

Journal: Journal of diabetes and its complications20060101

Title: Increased gastric motility during 5-HT4 agonist therapy reduces response fluctuations in Parkinson's disease.

Journal: Parkinsonism & related disorders20051201

Title: Validation and application of a high-performance liquid chromatography--tandem mass spectrometry assay for mosapride in human plasma.

Journal: Biomedical chromatography : BMC20050901

Title: The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression.

Journal: Clinical pharmacology and therapeutics20050901

Title: A 5-HT4 agonist, mosapride, enhances intrinsic rectorectal and rectoanal reflexes after removal of extrinsic nerves in guinea pigs.

Journal: American journal of physiology. Gastrointestinal and liver physiology20050801

Title: Effects of mosapride, a 5-hydroxytryptamine 4 receptor agonist, on electrical activity of the small intestine and cecum in horses.

Journal: American journal of veterinary research20050801

Title: Mosapride citrate, a novel 5-HT4 agonist and partial 5-HT3 antagonist, ameliorates constipation in parkinsonian patients.

Journal: Movement disorders : official journal of the Movement Disorder Society20050601

Title: Usefulness of famotidine in functional dyspepsia patient treatment: comparison among prokinetic, acid suppression and antianxiety therapies.

Journal: Alimentary pharmacology & therapeutics20050601

Title: Effects of famotidine, mosapride and tandospirone for treatment of functional dyspepsia.

Journal: Alimentary pharmacology & therapeutics20050601

Title: New strategy of therapy for functional dyspepsia using famotidine, mosapride and amitriptyline.

Journal: Alimentary pharmacology & therapeutics20050601

Title: Persistent cough following pulmonary resection: observational and empiric study of possible causes.

Journal: The Annals of thoracic surgery20050101

Title: Randomised, double-blind, comparative study to evaluate the efficacy and safety of ganaton (itopride hydrochloride) and mosapride citrate in the management of functional dyspepsia.

Journal: Journal of the Indian Medical Association20041201

Title: Development and validation of a liquid chromatographic method for determination of related-substances of mosapride citrate in bulk drugs and pharmaceuticals.

Journal: Journal of pharmaceutical and biomedical analysis20041119

Title: [The effect of mosapride on quality of life in functional dyspepsia].

Journal: The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi20040301

Title: [A randomized controlled Multi-center clinical trial on mosapride in the treatment of functional dyspepsia].

Journal: Zhonghua liu xing bing xue za zhi = Zhonghua liuxingbingxue zazhi20040201

Title: [New preparation method for barium enema: efficacy and administration of oral intestinal lavage solution with gastrointestinal prokinetic agent].

Journal: Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica20040101

Title: Comparison of efficacy of pantoprazole alone versus pantoprazole plus mosapride in therapy of gastroesophageal reflux disease: a randomized trial.

Journal: Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus20040101

Title: The effect of mosapride on oesophageal motor function and acid reflux in patients with gastro-oesophageal reflux disease.

Journal: European journal of gastroenterology & hepatology20031001

Title: Effect of mosapride on glycemic control and gastric emptying in type 2 diabetes mellitus patients with gastropathy.

Journal: Diabetes research and clinical practice20030901

Title: Investigation into the effects of mosapride on motility of Guinea pig stomach, ileum, and colon.

Journal: Yonsei medical journal20030830

Title: A 5-HT4 agonist mosapride enhances rectorectal and rectoanal reflexes in guinea pigs.

Journal: American journal of physiology. Gastrointestinal and liver physiology20030801

Title: Application of LC-MS/MS for the identification of a polar impurity in mosapride, a gastroprokinetic drug.

Journal: Journal of pharmaceutical and biomedical analysis20030601

Title: Relative efficacy of some prokinetic drugs in morphine-induced gastrointestinal transit delay in mice.

Journal: World journal of gastroenterology20030415

Title: Drug interaction between mosapride and erythromycin without electrocardiographic changes.

Journal: Japanese heart journal20030301

Title: Effect of temperature on the reversal in the retention order of the enantiomers of mosapride on Chiral-AGP.

Journal: Journal of biochemical and biophysical methods20021231

Title: Effects of mosapride citrate, a 5-HT4 receptor agonist, on colonic motility in conscious guinea pigs.

Journal: Japanese journal of pharmacology20021201

Title: A validated RP-HPLC method for the determination of mosapride citrate in bulk drug samples and pharmaceutical formulations.

Journal: Die Pharmazie20021201

Title: The determination of mosapride citrate in bulk drug samples and pharmaceutical dosage forms using HPLC.

Journal: Analytical sciences : the international journal of the Japan Society for Analytical Chemistry20021101

Title: [Reflux esophagitis].

Journal: Nihon rinsho. Japanese journal of clinical medicine20020801

Title: 5-HT4 receptor enhances the propulsive power of the peristaltic reflex in the rat distal colon.

Journal: Autonomic neuroscience : basic & clinical20020731

Title: Mosapride, a 5HT-4 receptor agonist, improves insulin sensitivity and glycaemic control in patients with Type II diabetes mellitus.

Journal: Diabetologia20020601

Title: Dose finding study of mosapride in functional dyspepsia: a placebo-controlled, randomized study.

Journal: Alimentary pharmacology & therapeutics20020501

Title: Drug-induced ventricular tachyarrhythmia in isolated rabbit hearts with atrioventricular block.

Journal: Pharmacology & toxicology20020501

Title: [Prokinetics of gastrointestinal system; its newer aspects with regard to motillity stimulants].

Journal: Nihon rinsho. Japanese journal of clinical medicine20020201

Title: Teratogenicity of the I(Kr)-blocker cisapride: relation to embryonic cardiac arrhythmia.

Journal: Reproductive toxicology (Elmsford, N.Y.)20020101

Title: Influence of mosapride citrate on gastric motility and autonomic nervous function: evaluation by spectral analyses of heart rate and blood pressure variabilities, and by electrogastrography.

Journal: Journal of gastroenterology20020101

Title: Gastrointestinal prokinetic drugs have different affinity for the human cardiac human ether-à-gogo K(+) channel.

Journal: The Journal of pharmacology and experimental therapeutics20011201

Title: Characteristics of fluvoxamine-induced nausea.

Journal: Psychiatry research20011130

Title: Effects of mosapride citrate on human plasma levels of motilin, gastrin, somatostatin, and secretin.

Journal: Biological & pharmaceutical bulletin20010901

Title: Effects of 5-HT(4) receptor agonists, cisapride and mosapride citrate on electrocardiogram in anaesthetized rats and guinea-pigs and conscious cats.

Journal: Pharmacology & toxicology20010801

Title: Torsades de pointes ventricular tachycardia induced by mosapride and flecainide in the presence of hypokalemia.

Journal: Pacing and clinical electrophysiology : PACE20010101

Title: The involvement of flavin-containing monooxygenase but not CYP3A4 in metabolism of itopride hydrochloride, a gastroprokinetic agent: comparison with cisapride and mosapride citrate.

Journal: Drug metabolism and disposition: the biological fate of chemicals20001001

Title: Tack J, et al. Systematic review: cardiovascular safety profile of 5-HT(4) agonists developed for gastrointestinal disorders. Aliment Pharmacol Ther. 2012 Apr;35(7):745-67.

Title: Curran MP, et al. Mosapride in gastrointestinal disorders. Drugs. 2008;68(7):981-91.

Title: Odaka T, et al. Serotonin 5- HT4 receptor agonist (mosapride citrate). Nihon Rinsho. 2006 Aug;64(8):1491-4.

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