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159190-45-1,MFCD00270890
Catalog No.:AA007DT3

159190-45-1 | L-NIL dihydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
10mg
≥95%
in stock  
$58.00   $40.00
- +
50mg
≥95%
in stock  
$212.00   $148.00
- +
100mg
≥95%
in stock  
$395.00   $276.00
- +
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  • Technical Information
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Technical Information
Catalog Number:
AA007DT3
Chemical Name:
L-NIL dihydrochloride
CAS Number:
159190-45-1
Molecular Formula:
C8H19Cl2N3O2
Molecular Weight:
260.1614
MDL Number:
MFCD00270890
SMILES:
CC(=NCCCCC(C(=O)O)N)N.Cl.Cl
Properties
Computed Properties
 
Complexity:
192  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
15  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
6  

Literature

Title: Synthesis and biological characterization of L-N(6)-(1-iminoethyl)lysine 5-tetrazole-amide, a prodrug of a selective iNOS inhibitor.

Journal: Journal of medicinal chemistry 20020411

Title: Consuelo Pasten, et al. l-NIL prevents the ischemia and reperfusion injury involving TLR-4, GST, clusterin, and NFAT-5 in mice. Am J Physiol Renal Physiol. 2019 Apr 1;316(4):F624-F634.

Title: Sharon Angela Tanuseputero, et al. Intravenous Arginine Administration Downregulates NLRP3 Inflammasome Activity and Attenuates Acute Kidney Injury in Mice with Polymicrobial Sepsis. Mediators Inflamm. 2020 May 11;2020:3201635.

Title: W M Moore, et al. L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase. J Med Chem. 1994 Nov 11;37(23):3886-8.

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Tags:159190-45-1 Molecular Formula|159190-45-1 MDL|159190-45-1 SMILES|159190-45-1 L-NIL dihydrochloride