Title: Understanding renal nuclear protein accumulation: an in vitro approach to explain an in vivo phenomenon.
Journal: Archives of toxicology 20171101
Title: Troxerutin inhibits 2,2',4,4'-tetrabromodiphenyl ether (BDE-47)-induced hepatocyte apoptosis by restoring proteasome function.
Journal: Toxicology letters 20150318
Title: Scutellarin inhibits high glucose-induced and hypoxia-mimetic agent-induced angiogenic effects in human retinal endothelial cells through reactive oxygen species/hypoxia-inducible factor-1α/vascular endothelial growth factor pathway.
Journal: Journal of cardiovascular pharmacology 20140901
Title: Broad-spectrum antimalarial activity of peptido sulfonyl fluorides, a new class of proteasome inhibitors.
Journal: Antimicrobial agents and chemotherapy 20130801
Title: Revisiting the role of the immunoproteasome in the activation of the canonical NF-κB pathway.
Journal: Molecular bioSystems 20120901
Title: Prenylation of Rho G-proteins: a novel mechanism regulating gene expression and protein stability in human trabecular meshwork cells.
Journal: Molecular neurobiology 20120801
Title: Fundamental reaction pathway and free energy profile for inhibition of proteasome by Epoxomicin.
Journal: Journal of the American Chemical Society 20120627
Title: Coordination between proteasome impairment and caspase activation leading to TAU pathology: neuroprotection by cAMP.
Journal: Cell death & disease 20120601
Title: The ubiquitin/proteasome system mediates entry and endosomal trafficking of Kaposi's sarcoma-associated herpesvirus in endothelial cells.
Journal: PLoS pathogens 20120501
Title: High sensitivity of embryonic stem cells to proteasome inhibitors correlates with low expression of heat shock protein and decrease of pluripotent cell marker expression.
Journal: BMB reports 20120501
Title: Proteasome inhibition can impair caspase-8 activation upon submaximal stimulation of apoptotic tumor necrosis factor-related apoptosis inducing ligand (TRAIL) signaling.
Journal: The Journal of biological chemistry 20120427
Title: Current advances in detection and treatment of babesiosis.
Journal: Current medicinal chemistry 20120401
Title: GILZ inhibits the mTORC2/AKT pathway in BCR-ABL(+) cells.
Journal: Oncogene 20120315
Title: Peptidomic analysis of HEK293T cells: effect of the proteasome inhibitor epoxomicin on intracellular peptides.
Journal: Journal of proteome research 20120302
Title: Protein repertoire impact of Ubiquitin-Proteasome System impairment: insight into the protective role of beta-estradiol.
Journal: Journal of proteomics 20120202
Title: Bortezomib resistance in a myeloma cell line is associated to PSMβ5 overexpression and polyploidy.
Journal: Leukemia research 20120201
Title: Mitochondrial calpain 10 is degraded by Lon protease after oxidant injury.
Journal: Archives of biochemistry and biophysics 20120115
Title: The origin of proteasome-inhibitor resistant HLA class I peptidomes: a study with HLA-A*68:01.
Journal: Molecular & cellular proteomics : MCP 20120101
Title: Distinct proteasome subpopulations in the alveolar space of patients with the acute respiratory distress syndrome.
Journal: Mediators of inflammation 20120101
Title: The biology of sexual development of Plasmodium: the design and implementation of transmission-blocking strategies.
Journal: Malaria journal 20120101
Title: Linkage of bacterial protein synthesis and presentation of MHC class I-restricted Listeria monocytogenes-derived antigenic peptides.
Journal: PloS one 20120101
Title: Protein quality control disruption by PKCβII in heart failure; rescue by the selective PKCβII inhibitor, βIIV5-3.
Journal: PloS one 20120101
Title: Derlin-1 deficiency is embryonic lethal, Derlin-3 deficiency appears normal, and Herp deficiency is intolerant to glucose load and ischemia in mice.
Journal: PloS one 20120101
Title: Direct ubiquitin independent recognition and degradation of a folded protein by the eukaryotic proteasomes-origin of intrinsic degradation signals.
Journal: PloS one 20120101
Title: Activity of clinically relevant antimalarial drugs on Plasmodium falciparum mature gametocytes in an ATP bioluminescence 'transmission blocking' assay.
Journal: PloS one 20120101
Title: Parkinson's disease DJ-1 L166P alters rRNA biogenesis by exclusion of TTRAP from the nucleolus and sequestration into cytoplasmic aggregates via TRAF6.
Journal: PloS one 20120101
Title: Disruption of the autophagy-lysosome pathway is involved in neuropathology of the nclf mouse model of neuronal ceroid lipofuscinosis.
Journal: PloS one 20120101
Title: Mechanism of chemical activation of Nrf2.
Journal: PloS one 20120101
Title: Escape from the Phagosome: The Explanation for MHC-I Processing of Mycobacterial Antigens?
Journal: Frontiers in immunology 20120101
Title: Dephosphorylation of specific sites in the kinase-specificity sequence domain leads to ubiquitin-mediated degradation of the tyrosine phosphatase STEP.
Journal: The Biochemical journal 20111115
Title: Smad3 signaling is required for satellite cell function and myogenic differentiation of myoblasts.
Journal: Cell research 20111101
Title: Involvement of ubiquitin-proteasome system in icariin-induced cardiomyocyte differentiation of embryonic stem cells using two-dimensional gel electrophoresis.
Journal: Journal of cellular biochemistry 20111101
Title: Relative contribution of different l-arginine sources to the substrate supply of endothelial nitric oxide synthase.
Journal: Journal of molecular and cellular cardiology 20111101
Title: The carboxypeptidase ACE shapes the MHC class I peptide repertoire.
Journal: Nature immunology 20111101
Title: Natural toxins implicated in the development of Parkinson's disease.
Journal: Therapeutic advances in neurological disorders 20111101
Title: P73 regulates cisplatin-induced apoptosis in ovarian cancer cells via a calcium/calpain-dependent mechanism.
Journal: Oncogene 20111013
Title: Proteasome inhibition can induce an autophagy-dependent apical activation of caspase-8.
Journal: Cell death and differentiation 20111001
Title: Cell stress induces TDP-43 pathological changes associated with ERK1/2 dysfunction: implications in ALS.
Journal: Acta neuropathologica 20110901
Title: Targeting of a chlamydial protease impedes intracellular bacterial growth.
Journal: PLoS pathogens 20110901
Title: The laminin-induced acrosome reaction in human sperm is mediated by Src kinases and the proteasome.
Journal: Biology of reproduction 20110801
Title: Leishmania donovani: proteasome-mediated down-regulation of methionine adenosyltransferase.
Journal: Parasitology 20110801
Title: Novel cell- and tissue-based assays for detecting misfolded and aggregated protein accumulation within aggresomes and inclusion bodies.
Journal: Cell biochemistry and biophysics 20110701
Title: Insulin-like growth factor-I mediates neuroprotection in proteasome inhibition-induced cytotoxicity in SH-SY5Y cells.
Journal: Molecular and cellular neurosciences 20110701
Title: Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: association with sequestosome 1/p62.
Journal: The Journal of biological chemistry 20110624
Title: Calcium dysregulation, mitochondrial pathology and protein aggregation in a culture model of amyotrophic lateral sclerosis: mechanistic relationship and differential sensitivity to intervention.
Journal: Neurobiology of disease 20110601
Title: A malaria gametocytocidal assay using oxidoreduction indicator, alamarBlue.
Journal: Molecular and biochemical parasitology 20110601
Title: Proteasome function is required for biological timing throughout the twenty-four hour cycle.
Journal: Current biology : CB 20110524
Title: Broad activation of the ubiquitin-proteasome system by Parkin is critical for mitophagy.
Journal: Human molecular genetics 20110501
Title: Proteasome inhibitors induce the presentation of an Epstein-Barr virus nuclear antigen 1-derived cytotoxic T lymphocyte epitope in Burkitt's lymphoma cells.
Journal: Immunology 20110501
Title: CMPG1-dependent cell death follows perception of diverse pathogen elicitors at the host plasma membrane and is suppressed by Phytophthora infestans RXLR effector AVR3a.
Journal: The New phytologist 20110501
Title: The role of the proteasome in the generation of MHC class I ligands and immune responses.
Journal: Cellular and molecular life sciences : CMLS 20110501
Title: The antiviral efficacy of HIV-specific CD8⁺ T-cells to a conserved epitope is heavily dependent on the infecting HIV-1 isolate.
Journal: PLoS pathogens 20110501
Title: CTL escape mediated by proteasomal destruction of an HIV-1 cryptic epitope.
Journal: PLoS pathogens 20110501
Title: A large and intact viral particle penetrates the endoplasmic reticulum membrane to reach the cytosol.
Journal: PLoS pathogens 20110501
Title: Semi-high throughput method of measuring proteasome inhibition in vitro and in cultured cells.
Journal: Cell biology and toxicology 20110401
Title: Participation of the sperm proteasome during in vitro fertilisation and the acrosome reaction in cattle.
Journal: Andrologia 20110401
Title: Geranylgeranylation facilitates proteasomal degradation of rho G-proteins in human trabecular meshwork cells.
Journal: Investigative ophthalmology & visual science 20110325
Title: Ikaros is degraded by proteasome-dependent mechanism in the early phase of apoptosis induction.
Journal: Biochemical and biophysical research communications 20110318
Title: The accumulation of neurotoxic proteins, induced by proteasome inhibition, is reverted by trehalose, an enhancer of autophagy, in human neuroblastoma cells.
Journal: Neurochemistry international 20110301
Title: Processing of optineurin in neuronal cells.
Journal: The Journal of biological chemistry 20110204
Title: A simple cell based assay to measure Parkin activity.
Journal: Journal of neurochemistry 20110201
Title: Bcl-2 homology domain 3-only proteins Puma and Bim mediate the vulnerability of CA1 hippocampal neurons to proteasome inhibition in vivo.
Journal: The European journal of neuroscience 20110201
Title: Environmental exposure, obesity, and Parkinson's disease: lessons from fat and old worms.
Journal: Environmental health perspectives 20110101
Title: Proteasome inhibition induces developmentally deregulated programs of apoptotic and autophagic cell death during Drosophila melanogaster oogenesis.
Journal: Cell biology international 20110101
Title: Proteasome activity imaging and profiling characterizes bacterial effector syringolin A.
Journal: Plant physiology 20110101
Title: Perturbation with intrabodies reveals that calpain cleavage is required for degradation of huntingtin exon 1.
Journal: PloS one 20110101
Title: Sperm proteasomes degrade sperm receptor on the egg zona pellucida during mammalian fertilization.
Journal: PloS one 20110101
Title: Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts.
Journal: PloS one 20110101
Title: Resveratrol protects leukemic cells against cytotoxicity induced by proteasome inhibitors via induction of FOXO1 and p27Kip1.
Journal: BMC cancer 20110101
Title: Cytotoxicity testing: measuring viable cells, dead cells, and detecting mechanism of cell death.
Journal: Methods in molecular biology (Clifton, N.J.) 20110101
Title: Production of free methylarginines via the proteasome and autophagy pathways in cultured cells.
Journal: Molecular medicine reports 20110101
Title: Firefly luciferase and RLuc8 exhibit differential sensitivity to oxidative stress in apoptotic cells.
Journal: PloS one 20110101
Title: Concurrent detection of autolysosome formation and lysosomal degradation by flow cytometry in a high-content screen for inducers of autophagy.
Journal: BMC biology 20110101
Title: Emerging role of carfilzomib in treatment of relapsed and refractory lymphoid neoplasms and multiple myeloma.
Journal: Core evidence 20110101
Title: Combined 3D-QSAR, molecular docking and molecular dynamics study on derivatives of peptide epoxyketone and tyropeptin-boronic acid as inhibitors against the β5 subunit of human 20S proteasome.
Journal: International journal of molecular sciences 20110101
Title: A ubiquitin independent degradation pathway utilized by a hepatitis B virus envelope protein to limit antigen presentation.
Journal: PloS one 20110101
Title: Dysregulation of iron metabolism in Alzheimer's disease, Parkinson's disease, and amyotrophic lateral sclerosis.
Journal: Advances in pharmacological sciences 20110101
Title: Molecular mechanisms of bortezomib resistant adenocarcinoma cells.
Journal: PloS one 20110101
Title: Bifunctional anti-huntingtin proteasome-directed intrabodies mediate efficient degradation of mutant huntingtin exon 1 protein fragments.
Journal: PloS one 20110101
Title: Lysine 419 targets human glucocorticoid receptor for proteasomal degradation.
Journal: Steroids 20101201
Title: Metabolism and action of proteasome inhibitors in primary human hepatocytes.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20101201
Title: Prolongation of myocardial viability by proteasome inhibition during hypothermic organ preservation.
Journal: Biochemical and biophysical research communications 20101029
Title: Sugar amino acid based peptide epoxyketones as potential proteasome inhibitors.
Journal: Bioorganic chemistry 20101001
Title: Proteasome inhibition in medaka brain induces the features of Parkinson's disease.
Journal: Journal of neurochemistry 20101001
Title: Secreted immunodominant Mycobacterium tuberculosis antigens are processed by the cytosolic pathway.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20101001
Title: Biological effects of induced MYCN hyper-expression in MYCN-amplified neuroblastomas.
Journal: International journal of oncology 20101001
Title: Epstein Barr virus-encoded EBNA1 interference with MHC class I antigen presentation reveals a close correlation between mRNA translation initiation and antigen presentation.
Journal: PLoS pathogens 20101001
Title: Characterization of a new series of non-covalent proteasome inhibitors with exquisite potency and selectivity for the 20S beta5-subunit.
Journal: The Biochemical journal 20100915
Title: Alpha,beta-unsaturated N-acylpyrrole peptidyl derivatives: new proteasome inhibitors.
Journal: Journal of medicinal chemistry 20100909
Title: Activation of PKN mediates survival of cardiac myocytes in the heart during ischemia/reperfusion.
Journal: Circulation research 20100903
Title: Accumulation of polyubiquitylated proteins in response to Ala-Ala-Phe-chloromethylketone is independent of the inhibition of Tripeptidyl peptidase II.
Journal: Biochimica et biophysica acta 20100901
Title: Activity-based profiling reveals reactivity of the murine thymoproteasome-specific subunit beta5t.
Journal: Chemistry & biology 20100827
Title: Effect of endogenous mutant and wild-type PINK1 on Parkin in fibroblasts from Parkinson disease patients.
Journal: Human molecular genetics 20100815
Title: Malaria gametocytogenesis.
Journal: Molecular and biochemical parasitology 20100801
Title: sAPPalpha antagonizes dendritic degeneration and neuron death triggered by proteasomal stress.
Journal: Molecular and cellular neurosciences 20100801
Title: The Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide.
Journal: PLoS pathogens 20100801
Title: A caspase cleaved form of tau is preferentially degraded through the autophagy pathway.
Journal: The Journal of biological chemistry 20100716
Title: CR6-interacting factor 1 (CRIF1) regulates NF-E2-related factor 2 (NRF2) protein stability by proteasome-mediated degradation.
Journal: The Journal of biological chemistry 20100709
Title: Regulation of aurora B kinase by the lipid raft protein flotillin-1.
Journal: The Journal of biological chemistry 20100702
Title: Evidence for a role of immunoproteasomes in regulating cardiac muscle mass in diabetic mice.
Journal: Journal of molecular and cellular cardiology 20100701
Title: Differential expression patterns of Puma and Hsp70 following proteasomal stress in the hippocampus are key determinants of neuronal vulnerability.
Journal: Journal of neurochemistry 20100701
Title: Zinc mesoporphyrin induces rapid proteasomal degradation of hepatitis C nonstructural 5A protein in human hepatoma cells.
Journal: Gastroenterology 20100501
Title: Autophagy is the predominant process induced by arsenite in human lymphoblastoid cell lines.
Journal: Toxicology and applied pharmacology 20100501
Title: Production of an antigenic peptide by insulin-degrading enzyme.
Journal: Nature immunology 20100501
Title: Induced, selective proteolysis of MLK3 negatively regulates MLK3/JNK signalling.
Journal: The Biochemical journal 20100414
Title: Reciprocal effects of alpha-synuclein overexpression and proteasome inhibition in neuronal cells and tissue.
Journal: Neurotoxicity research 20100401
Title: Effect of proteasome inhibitors with different chemical structures on the ubiquitin-proteasome system in vitro.
Journal: Veterinary pathology 20100301
Title: Evaluation of the in vitro growth-inhibitory effect of epoxomicin on Babesia parasites.
Journal: Veterinary parasitology 20100120
Title: Ischaemic preconditioning improves proteasomal activity and increases the degradation of deltaPKC during reperfusion.
Journal: Cardiovascular research 20100115
Title: The cell senescence inducing gene product MORF4 is regulated by degradation via the ubiquitin/proteasome pathway.
Journal: Experimental cell research 20100101
Title: Central insulin signaling is attenuated by long-term insulin exposure via insulin receptor substrate-1 serine phosphorylation, proteasomal degradation, and lysosomal insulin receptor degradation.
Journal: Endocrinology 20100101
Title: Circulating proteasomes after burn injury.
Journal: Journal of burn care & research : official publication of the American Burn Association 20100101
Title: Loss of ALS2/Alsin exacerbates motor dysfunction in a SOD1-expressing mouse ALS model by disturbing endolysosomal trafficking.
Journal: PloS one 20100101
Title: Inhibition of hypoxia-inducible factor-1alpha (HIF-1alpha) protein synthesis by DNA damage inducing agents.
Journal: PloS one 20100101
Title: CD8+ T cell priming by dendritic cell vaccines requires antigen transfer to endogenous antigen presenting cells.
Journal: PloS one 20100101
Title: Characterization of the Brain 26S Proteasome and its Interacting Proteins.
Journal: Frontiers in molecular neuroscience 20100101
Title: Methylglyoxal alters the function and stability of critical components of the protein quality control.
Journal: PloS one 20100101
Title: BAMBI is expressed in endothelial cells and is regulated by lysosomal/autolysosomal degradation.
Journal: PloS one 20100101
Title: Regulators of the proteasome pathway, Uch37 and Rpn13, play distinct roles in mouse development.
Journal: PloS one 20100101
Title: Cell type-specific neuroprotective activity of untranslocated prion protein.
Journal: PloS one 20100101
Title: Structural determinants of PINK1 topology and dual subcellular distribution.
Journal: BMC cell biology 20100101
Title: Proteasome inhibition and its therapeutic potential in multiple myeloma.
Journal: Biologics : targets & therapy 20100101
Title: The chaperone-dependent ubiquitin ligase CHIP targets HIF-1α for degradation in the presence of methylglyoxal.
Journal: PloS one 20100101
Title: Huntingtin cleavage product A forms in neurons and is reduced by gamma-secretase inhibitors.
Journal: Molecular neurodegeneration 20100101
Title: Chemical genetics approach to restoring p27Kip1 reveals novel compounds with antiproliferative activity in prostate cancer cells.
Journal: BMC biology 20100101
Title: Niclosamide prevents the formation of large ubiquitin-containing aggregates caused by proteasome inhibition.
Journal: PloS one 20100101
Title: A subset of 26S proteasomes is activated at critically low ATP concentrations and contributes to myocardial injury during cold ischemia.
Journal: Biochemical and biophysical research communications 20091225
Title: The ubiquitin-interacting motifs of S5a as a unique upstream inhibitor of the 26S proteasome.
Journal: Biochemical and biophysical research communications 20091030
Title: The microtubule-targeting agent T0070907 induces proteasomal degradation of tubulin.
Journal: Biochemical and biophysical research communications 20091016
Title: Spirodiepoxides: synthesis of epoxomicinoids.
Journal: The Journal of organic chemistry 20091016
Title: Perturbation of DNA repair pathways by proteasome inhibitors corresponds to enhanced chemosensitivity of cells to DNA damage-inducing agents.
Journal: Cancer chemotherapy and pharmacology 20091001
Title: Regulation of stathmin phosphorylation in mouse liver progenitor-29 cells during proteasome inhibition.
Journal: Proteomics 20091001
Title: Parkin deficiency increases the resistance of midbrain neurons and glia to mild proteasome inhibition: the role of autophagy and glutathione homeostasis.
Journal: Journal of neurochemistry 20090901
Title: Limiting transport steps and novel interactions of Connexin-43 along the secretory pathway.
Journal: Histochemistry and cell biology 20090901
Title: Intermediate filament transcription in astrocytes is repressed by proteasome inhibition.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090801
Title: Proteasome inhibitors impair RANKL-induced NF-kappaB activity in osteoclast-like cells via disruption of p62, TRAF6, CYLD, and IkappaBalpha signaling cascades.
Journal: Journal of cellular physiology 20090801
Title: Nonsense-mediated mRNA decay and ubiquitin-proteasome system regulate cardiac myosin-binding protein C mutant levels in cardiomyopathic mice.
Journal: Circulation research 20090731
Title: Modulation of skeletal muscle insulin signaling with chronic caloric restriction in cynomolgus monkeys.
Journal: Diabetes 20090701
Title: Alveolar extracellular 20S proteasome in patients with acute respiratory distress syndrome.
Journal: American journal of respiratory and critical care medicine 20090615
Title: Proteasome inhibitor differentially regulates expression of the major immediate early genes of human cytomegalovirus in human central nervous system-derived cell lines.
Journal: Virus research 20090601
Title: Induction of macroautophagy by overexpression of the Parkinson's disease-associated GPR37 receptor.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20090601
Title: Effect of proteasome inhibitors on endotoxin-induced diaphragm dysfunction.
Journal: American journal of physiology. Lung cellular and molecular physiology 20090601
Title: Targeting transcription factor NFkappaB: comparative analysis of proteasome and IKK inhibitors.
Journal: Cell cycle (Georgetown, Tex.) 20090515
Title: Upregulation and maintenance of gap junctional communication in lens cells.
Journal: Experimental eye research 20090501
Title: Participation of the human sperm proteasome in the capacitation process and its regulation by protein kinase A and tyrosine kinase.
Journal: Biology of reproduction 20090501
Title: Transcriptional and posttranslational regulation of clusterin by the two main cellular proteolytic pathways.
Journal: Free radical biology & medicine 20090501
Title: Cell-based bioluminescent assays for all three proteasome activities in a homogeneous format.
Journal: Analytical biochemistry 20090415
Title: PKA rapidly enhances proteasome assembly and activity in in vivo canine hearts.
Journal: Journal of molecular and cellular cardiology 20090401
Title: New cyclic peptide proteasome inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20090401
Title: The Mycobacterium tuberculosis phagosome is a HLA-I processing competent organelle.
Journal: PLoS pathogens 20090401
Title: Proteasomal inhibition reduces parkin mRNA in PC12 and SH-SY5Y cells.
Journal: Parkinsonism & related disorders 20090301
Title: Contrasting proteome biology and functional heterogeneity of the 20 S proteasome complexes in mammalian tissues.
Journal: Molecular & cellular proteomics : MCP 20090201
Title: Inhibition of the 20S proteosome by a protein proteinase inhibitor: evidence that a natural serine proteinase inhibitor can inhibit a threonine proteinase.
Journal: Journal of biochemistry 20090201
Title: Detection and possible role of proteasomes in the bronchoalveolar space of the injured lung.
Journal: Physiological research 20090101
Title: Ectodermal-neural cortex 1 down-regulates Nrf2 at the translational level.
Journal: PloS one 20090101
Title: Regulation of ErbB2 receptor status by the proteasomal DUB POH1.
Journal: PloS one 20090101
Title: Proteasome-independent degradation of HIV-1 in naturally non-permissive human placental trophoblast cells.
Journal: Retrovirology 20090101
Title: Concentration-dependent effects of proteasomal inhibition on tau processing in a cellular model of tauopathy.
Journal: International journal of clinical and experimental pathology 20090101
Title: Protein kinase Cdelta stimulates proteasome-dependent degradation of C/EBPalpha during apoptosis induction of leukemic cells.
Journal: PloS one 20090101
Title: Loss of anti-Bax function in Gerstmann-Sträussler-Scheinker syndrome-associated prion protein mutants.
Journal: PloS one 20090101
Title: Immature and mature species of the human Prostacyclin Receptor are ubiquitinated and targeted to the 26S proteasomal or lysosomal degradation pathways, respectively.
Journal: Journal of molecular signaling 20090101
Title: Proteasomes in human bronchoalveolar lavage fluid after burn and inhalation injury.
Journal: Journal of burn care & research : official publication of the American Burn Association 20090101
Title: Consequences of the DYT1 mutation on torsinA oligomerization and degradation.
Journal: Neuroscience 20081202
Title: The peroxin Pex14p is involved in LC3-dependent degradation of mammalian peroxisomes.
Journal: Experimental cell research 20081115
Title: Induction of BAG2 protein during proteasome inhibitor-induced apoptosis in thyroid carcinoma cells.
Journal: British journal of pharmacology 20081101
Title: Assessment of circulating proteasome chymotrypsin-like activity in plasma of patients with acute and chronic leukemias.
Journal: Clinical biochemistry 20081101
Title: Urea-mediated cross-presentation of soluble Epstein-Barr virus BZLF1 protein.
Journal: PLoS pathogens 20081101
Title: Gamma-secretase represents a therapeutic target for the treatment of invasive glioma mediated by the p75 neurotrophin receptor.
Journal: PLoS biology 20081101
Title: Oxidants and Ca+2 induce PGC-1alpha degradation through calpain.
Journal: Archives of biochemistry and biophysics 20081015
Title: Proteasome inhibition decreases cardiac remodeling after initiation of pressure overload.
Journal: American journal of physiology. Heart and circulatory physiology 20081001
Title: Proteasome inhibition in hypertrophied myocardium.
Journal: American journal of physiology. Heart and circulatory physiology 20081001
Title: Proteomic profiling of gamma-secretase substrates and mapping of substrate requirements.
Journal: PLoS biology 20081001
Title: Human papillomavirus type 45 E7 is a transforming protein inducing retinoblastoma protein degradation and anchorage-independent cell cycle progression.
Journal: Virology 20080915
Title: Overexpression of endoplasmic reticulum-resident chaperone attenuates cardiomyocyte death induced by proteasome inhibition.
Journal: Cardiovascular research 20080901
Title: Proteasome inhibition and stress compromise the heart in chemotherapy.
Journal: Cardiovascular research 20080901
Title: Protein Never in Mitosis Gene A Interacting-1 (PIN1) regulates degradation of inducible nitric oxide synthase in endothelial cells.
Journal: American journal of physiology. Cell physiology 20080901
Title: Limitations of SLLVY-AMC in calpain and proteasome measurements.
Journal: Biochemical and biophysical research communications 20080704
Title: C-terminal constrained phenylalanine as a pharmacophoric unit in peptide-based proteasome inhibitors.
Journal: European journal of medicinal chemistry 20080701
Title: Modulation of peroxisome proliferator-activated receptor gamma stability and transcriptional activity in adipocytes by resveratrol.
Journal: Metabolism: clinical and experimental 20080701
Title: Proteasomal abnormalities in cortical Lewy body disease and the impact of proteasomal inhibition within cortical and cholinergic systems.
Journal: Journal of neural transmission (Vienna, Austria : 1996) 20080601
Title: Two-dimensional patterning by a trapping/depletion mechanism: the role of TTG1 and GL3 in Arabidopsis trichome formation.
Journal: PLoS biology 20080601
Title: Cigarette smoke induces genetic instability in airway epithelial cells by suppressing FANCD2 expression.
Journal: British journal of cancer 20080520
Title: Aspirin sensitizes cancer cells to TRAIL-induced apoptosis by reducing survivin levels.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20080515
Title: Proteasomes cleave at multiple sites within polyglutamine tracts: activation by PA28gamma(K188E).
Journal: The Journal of biological chemistry 20080509
Title: Proteasomal degradation of TRIM5alpha during retrovirus restriction.
Journal: PLoS pathogens 20080501
Title: Immunocytochemical and ultrastructural analyses of the function of the ubiquitin-proteasome system during spermiogenesis with the use of the inhibitors of proteasome proteolytic activity in the alga, Chara vulgaris.
Journal: Biology of reproduction 20080401
Title: Upregulation of DR5 by proteasome inhibitors potently sensitizes glioma cells to TRAIL-induced apoptosis.
Journal: The FEBS journal 20080401
Title: Vinyl ester-based cyclic peptide proteasome inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20080315
Title: Incomplete nonsense-mediated decay of mutant lamin A/C mRNA provokes dilated cardiomyopathy and ventricular tachycardia.
Journal: Journal of molecular medicine (Berlin, Germany) 20080301
Title: Effect of proteasome inhibitors on proliferation and apoptosis of human cutaneous melanoma-derived cell lines.
Journal: The British journal of dermatology 20080301
Title: Tripeptidyl peptidase II is dispensable for the generation of both proteasome-dependent and proteasome-independent ligands of HLA-B27 and other class I molecules.
Journal: European journal of immunology 20080301
Title: Zinc mesoporphyrin induces rapid and marked degradation of the transcription factor Bach1 and up-regulates HO-1.
Journal: Biochimica et biophysica acta 20080301
Title: Proteasome activation during cardiac hypertrophy by the chaperone H11 Kinase/Hsp22.
Journal: Cardiovascular research 20080201
Title: Oxidative injury induces selective rather than global inhibition of proteasomal activity.
Journal: Journal of molecular and cellular cardiology 20080201
Title: Antioxidants block proteasome inhibitor function in endometrial carcinoma cells.
Journal: Anti-cancer drugs 20080201
Title: Cardiac proteasome dysfunction during cold ischemic storage and reperfusion in a murine heart transplantation model.
Journal: Biochemical and biophysical research communications 20080125
Title: Lrig1 is an endogenous inhibitor of Ret receptor tyrosine kinase activation, downstream signaling, and biological responses to GDNF.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20080102
Title: Components of the ubiquitin-proteasome pathway compete for surfaces on Rad23 family proteins.
Journal: BMC biochemistry 20080101
Title: Dominant negative mutant cyclin T1 proteins inhibit HIV transcription by specifically degrading Tat.
Journal: Retrovirology 20080101
Title: Riluzole increases the amount of latent HSF1 for an amplified heat shock response and cytoprotection.
Journal: PloS one 20080101
Title: Comprehensive study of proteasome inhibitors against Plasmodium falciparum laboratory strains and field isolates from Gabon.
Journal: Malaria journal 20080101
Title: The UPS: a promising target for breast cancer treatment.
Journal: BMC biochemistry 20080101
Title: Transcription Regulation by Class III Histone Deacetylases (HDACs)-Sirtuins.
Journal: Translational oncogenomics 20080101
Title: Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes.
Journal: Bioorganic & medicinal chemistry letters 20071115
Title: The E3 Ligase MuRF1 degrades myosin heavy chain protein in dexamethasone-treated skeletal muscle.
Journal: Cell metabolism 20071101
Title: Turnover of mitochondrial steroidogenic acute regulatory (StAR) protein by Lon protease: the unexpected effect of proteasome inhibitors.
Journal: Molecular endocrinology (Baltimore, Md.) 20070901
Title: Hepatitis C virus induces E6AP-dependent degradation of the retinoblastoma protein.
Journal: PLoS pathogens 20070901
Title: Control of chronic pain by the ubiquitin proteasome system in the spinal cord.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20070801
Title: Specific blockage of ligand-induced degradation of the Ah receptor by proteasome but not calpain inhibitors in cell culture lines from different species.
Journal: Biochemical pharmacology 20070630
Title: Real-time fluorescence detection of ERAD substrate retrotranslocation in a mammalian in vitro system.
Journal: Cell 20070601
Title: The proteasome inhibitor PS-341 (bortezomib) up-regulates DR5 expression leading to induction of apoptosis and enhancement of TRAIL-induced apoptosis despite up-regulation of c-FLIP and survivin expression in human NSCLC cells.
Journal: Cancer research 20070515
Title: Mixing of peptides and electrophilic traps gives rise to potent, broad-spectrum proteasome inhibitors.
Journal: Organic & biomolecular chemistry 20070507
Title: Extracellular proteasome in the human alveolar space: a new housekeeping enzyme?
Journal: American journal of physiology. Lung cellular and molecular physiology 20070501
Title: Proteasome-independent HLA-B27 ligands arise mainly from small basic proteins.
Journal: Molecular & cellular proteomics : MCP 20070501
Title: Effect of fibronectin on proteasome activity, acrosome reaction, tyrosine phosphorylation and intracellular calcium concentrations of human sperm.
Journal: Human reproduction (Oxford, England) 20070501
Title: Dose-dependent inhibition of proteasome activity by a mutant ubiquitin associated with neurodegenerative disease.
Journal: Journal of cell science 20070501
Title: Analysis of nucleolar protein dynamics reveals the nuclear degradation of ribosomal proteins.
Journal: Current biology : CB 20070501
Title: Ubiquitinated-protein aggregates form in pancreatic beta-cells during diabetes-induced oxidative stress and are regulated by autophagy.
Journal: Diabetes 20070401
Title: Peroxisome proliferator-activated receptor gamma-independent suppression of androgen receptor expression by troglitazone mechanism and pharmacologic exploitation.
Journal: Cancer research 20070401
Title: Apoptosis induced by proteasome inhibition in cancer cells: predominant role of the p53/PUMA pathway.
Journal: Oncogene 20070315
Title: Arkadia enhances Nodal/TGF-beta signaling by coupling phospho-Smad2/3 activity and turnover.
Journal: PLoS biology 20070301
Title: The proteasome inhibitors bortezomib and PR-171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells.
Journal: British journal of haematology 20070301
Title: PPARgamma inhibitors reduce tubulin protein levels by a PPARgamma, PPARdelta and proteasome-independent mechanism, resulting in cell cycle arrest, apoptosis and reduced metastasis of colorectal carcinoma cells.
Journal: International journal of cancer 20070201
Title: High-throughput bioluminescence screening of ubiquitin-proteasome pathway inhibitors from chemical and natural sources.
Journal: Journal of biomolecular screening 20070201
Title: Turnover of StAR protein: roles for the proteasome and mitochondrial proteases.
Journal: Molecular and cellular endocrinology 20070201
Title: Proteasomal chymotrypsin-like peptidase activity is required for essential functions of human monocyte-derived dendritic cells.
Journal: Immunology 20070101
Title: SIVSM/HIV-2 Vpx proteins promote retroviral escape from a proteasome-dependent restriction pathway present in human dendritic cells.
Journal: Retrovirology 20070101
Title: Role of ubiquitination in IGF-1 receptor signaling and degradation.
Journal: PloS one 20070101
Title: The regulation of cyclin D1 degradation: roles in cancer development and the potential for therapeutic invention.
Journal: Molecular cancer 20070101
Title: HIV-1 Vpr activates the G2 checkpoint through manipulation of the ubiquitin proteasome system.
Journal: Virology journal 20070101
Title: Proteasome activity and its relationship with protein phosphorylation during capacitation and acrosome reaction in human spermatozoa.
Journal: Society of Reproduction and Fertility supplement 20070101
Title: Role of the ubiquitin proteasome system in Parkinson's disease.
Journal: BMC biochemistry 20070101
Title: Patented small molecule inhibitors in the ubiquitin proteasome system.
Journal: BMC biochemistry 20070101
Title: The ubiquitin proteasome system in Huntington's disease and the spinocerebellar ataxias.
Journal: BMC biochemistry 20070101
Title: Role of proteasomes in disease.
Journal: BMC biochemistry 20070101
Title: Targeting human immunodeficiency virus type 1 assembly, maturation and budding.
Journal: Drug target insights 20070101
Title: Comparison of the neurotoxic effects of proteasomal inhibitors in primary mesencephalic cultures.
Journal: Experimental neurology 20061201
Title: AbetaPP-overexpression and proteasome inhibition increase alphaB-crystallin in cultured human muscle: relevance to inclusion-body myositis.
Journal: Neuromuscular disorders : NMD 20061201
Title: Activation of the cardiac proteasome during pressure overload promotes ventricular hypertrophy.
Journal: Circulation 20061024
Title: Proteasomal regulation of cardiac hypertrophy: is demolition necessary for building?
Journal: Circulation 20061024
Title: Deubiquitinating enzyme Ubp6 functions noncatalytically to delay proteasomal degradation.
Journal: Cell 20061006
Title: Cyclic AMP delays neutrophil apoptosis via stabilization of Mcl-1.
Journal: FEBS letters 20060821
Title: Roles of the ubiquitin/proteasome pathway in pollen tube growth with emphasis on MG132-induced alterations in ultrastructure, cytoskeleton, and cell wall components.
Journal: Plant physiology 20060801
Title: Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.
Journal: Annals of neurology 20060801
Title: Histone H2A.z is essential for cardiac myocyte hypertrophy but opposed by silent information regulator 2alpha.
Journal: The Journal of biological chemistry 20060714
Title: Plasmodia express two threonine-peptidase complexes during asexual development.
Journal: Molecular and biochemical parasitology 20060701
Title: HIV-1 reverse transcriptase targeted for proteasomal degradation as a prototype vaccine against drug-resistant HIV-1.
Journal: Vaccine 20060522
Title: Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and cellular properties of potent, selective proteasome inhibitors.
Journal: Journal of medicinal chemistry 20060518
Title: Extracellular matrix metalloproteinase inducer (CD147) confers resistance of breast cancer cells to Anoikis through inhibition of Bim.
Journal: The Journal of biological chemistry 20060407
Title: The involvement of immunoproteasomes in induction of MHC class I-restricted immunity targeting Toxoplasma SAG1.
Journal: Microbes and infection 20060401
Title: Ubiquitin-proteasome system stress sensitizes ovarian cancer to proteasome inhibitor-induced apoptosis.
Journal: Cancer research 20060401
Title: Glial cell line-derived neurotrophic factor-dependent recruitment of Ret into lipid rafts enhances signaling by partitioning Ret from proteasome-dependent degradation.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20060308
Title: Proteasome inhibitor-induced apoptosis in human monocyte-derived dendritic cells.
Journal: European journal of immunology 20060301
Title: Major histocompatibility complex class I restricted T-cell autoreactivity in human peripheral blood mononuclear cells.
Journal: Cellular immunology 20060301
Title: Characterization of endoplasmic reticulum-associated degradation of a protein S mutant identified in a family of quantitative protein S deficiency.
Journal: Thrombosis research 20060101
Title: Histone deacetylase inhibitor, trichostatin A induces ubiquitin-dependent cyclin D1 degradation in MCF-7 breast cancer cells.
Journal: Molecular cancer 20060101
Title: Probing protein function with small molecules.
Journal: Ernst Schering Research Foundation workshop 20060101
Title: Presenilin-dependent intramembrane cleavage of ephrin-B1.
Journal: Molecular neurodegeneration 20060101
Title: Proteasome inhibitors sensitize colon carcinoma cells to TRAIL-induced apoptosis via enhanced release of Smac/DIABLO from the mitochondria.
Journal: Pathology oncology research : POR 20060101
Title: Detection of a proteasome in Pneumocystis carinii and its modulation by specific proteasome inhibitors.
Journal: The Journal of eukaryotic microbiology 20060101
Title: [Artifitial increase of HIV-1 reverse transcriptase turnover through proteasome pathway].
Journal: Molekuliarnaia biologiia 20060101
Title: Antiviral activity of proteasome inhibitors in herpes simplex virus-1 infection: role of nuclear factor-kappaB.
Journal: Antiviral therapy 20060101
Title: Assessing neuroprotection in Parkinson's disease: from the animal models to molecular neuroimaging in vivo.
Journal: Journal of neural transmission. Supplementum 20060101
Title: Role of the cytokine-induced SH2 domain-containing protein CIS in growth hormone receptor internalization.
Journal: The Journal of biological chemistry 20051111
Title: The proteasome metabolizes peptide-mediated nonviral gene delivery systems.
Journal: Gene therapy 20051101
Title: Identification of mono-ubiquitinated LDH-A in skeletal muscle cells exposed to oxidative stress.
Journal: Biochemical and biophysical research communications 20051028
Title: [Development of BMP-related drugs].
Journal: Nihon rinsho. Japanese journal of clinical medicine 20051001
Title: Deubiquitination by proteasome is coordinated with substrate translocation for proteolysis in vivo.
Journal: Experimental cell research 20050715
Title: MAG induces regulated intramembrane proteolysis of the p75 neurotrophin receptor to inhibit neurite outgrowth.
Journal: Neuron 20050616
Title: Cooperative cytotoxicity of proteasome inhibitors and tumor necrosis factor-related apoptosis-inducing ligand in chemoresistant Bcl-2-overexpressing cells.
Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20050601
Title: Dopaminergic neurons in rat ventral midbrain cultures undergo selective apoptosis and form inclusions, but do not up-regulate iHSP70, following proteasomal inhibition.
Journal: Journal of neurochemistry 20050601
Title: Tau is not normally degraded by the proteasome.
Journal: Journal of neuroscience research 20050501
Title: Evidence for a protective role of Mcl-1 in proteasome inhibitor-induced apoptosis.
Journal: Blood 20050415
Title: Evidence that insulin secretion influences SNAP-25 through proteasomal activation.
Journal: Biochemical and biophysical research communications 20050415
Title: Peroxisome proliferator-activated receptor gamma-independent ablation of cyclin D1 by thiazolidinediones and their derivatives in breast cancer cells.
Journal: Molecular pharmacology 20050401
Title: Transforming growth factor-beta differentially inhibits MyD88-dependent, but not TRAM- and TRIF-dependent, lipopolysaccharide-induced TLR4 signaling.
Journal: The Journal of biological chemistry 20050218
Title: Presentation of endogenously synthesized MHC class II-restricted epitopes by MHC class II cancer vaccines is independent of transporter associated with Ag processing and the proteasome.
Journal: Journal of immunology (Baltimore, Md. : 1950) 20050215
Title: Assaying degradation and deubiquitination of a ubiquitinated substrate by purified 26S proteasomes.
Journal: Methods in enzymology 20050101
Title: Development and characterization of proteasome inhibitors.
Journal: Methods in enzymology 20050101
Title: Spirodiepoxides in total synthesis: epoxomicin.
Journal: Journal of the American Chemical Society 20041201
Title: NPM/ALK downregulates p27Kip1 in a PI-3K-dependent manner.
Journal: Experimental hematology 20041201
Title: Inhibitors of the eukaryotic 20S proteasome core particle: a structural approach.
Journal: Biochimica et biophysica acta 20041129
Title: Coordination of oxidized protein hydrolase and the proteasome in the clearance of cytotoxic denatured proteins.
Journal: Biochemical and biophysical research communications 20041105
Title: Proteasome-dependent degradation of ERalpha but not ERbeta in cultured mouse aorta smooth muscle cells.
Journal: Molecular and cellular endocrinology 20040930
Title: Ubiquitin-dependent lysosomal degradation of the HNE-modified proteins in lens epithelial cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20040901
Title: Trypanocidal effect of alpha',beta'-epoxyketones indicates that trypanosomes are particularly sensitive to inhibitors of proteasome trypsin-like activity.
Journal: International journal of antimicrobial agents 20040901
Title: Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease.
Journal: Annals of neurology 20040701
Title: Extracellular localization of proteasomes in human sperm.
Journal: Molecular reproduction and development 20040501
Title: GSK3 beta-dependent phosphorylation of the alpha NAC coactivator regulates its nuclear translocation and proteasome-mediated degradation.
Journal: Biochemistry 20040316
Title: Long term proteasome inhibition does not preferentially afflict motor neurons in organotypical spinal cord cultures.
Journal: Amyotrophic lateral sclerosis and other motor neuron disorders : official publication of the World Federation of Neurology, Research Group on Motor Neuron Diseases 20040301
Title: Purification of the Arabidopsis 26 S proteasome: biochemical and molecular analyses revealed the presence of multiple isoforms.
Journal: The Journal of biological chemistry 20040220
Title: Establishment and some characteristics of epoxomicin (a proteasome inhibitor) resistant variants of the human squamous cell carcinoma cell line, A431.
Journal: International journal of oncology 20040201
Title: Proteasome inhibition induces a senescence-like phenotype in primary human fibroblasts cultures.
Journal: Biogerontology 20040101
Title: Proteasome inhibitors: their effects on arachidonic acid release from cells in culture and arachidonic acid metabolism in rat liver cells.
Journal: BMC pharmacology 20040101
Title: Endoplasmic reticulum degradation impedes olfactory G-protein coupled receptor functional expression.
Journal: BMC cell biology 20040101
Title: Cytosolic prion protein is not toxic and protects against Bax-mediated cell death in human primary neurons.
Journal: The Journal of biological chemistry 20031017
Title: Fine structure and biochemical mechanisms underlying nigrostriatal inclusions and cell death after proteasome inhibition.
Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20031001
Title: Requirement of the proteasome for the trimming of signal peptide-derived epitopes presented by the nonclassical major histocompatibility complex class I molecule HLA-E.
Journal: The Journal of biological chemistry 20030905
Title: Dysfunction of mitochondrial complex I and the proteasome: interactions between two biochemical deficits in a cellular model of Parkinson's disease.
Journal: Journal of neurochemistry 20030901
Title: A transgenic mouse model of the ubiquitin/proteasome system.
Journal: Nature biotechnology 20030801
Title: Central role of the proteasome in senescence and survival of human fibroblasts: induction of a senescence-like phenotype upon its inhibition and resistance to stress upon its activation.
Journal: The Journal of biological chemistry 20030725
Title: Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro.
Journal: The Journal of clinical investigation 20030601
Title: Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substrates.
Journal: The international journal of biochemistry & cell biology 20030501
Title: Loss of function and impaired degradation of a cataract-associated mutant connexin50.
Journal: European journal of cell biology 20030501
Title: An essential role for tripeptidyl peptidase in the generation of an MHC class I epitope.
Journal: Nature immunology 20030401
Title: Parkin prevents mitochondrial swelling and cytochrome c release in mitochondria-dependent cell death.
Journal: Human molecular genetics 20030301
Title: Inducible p27(Kip1) expression inhibits proliferation of K562 cells and protects against apoptosis induction by proteasome inhibitors.
Journal: Cell death and differentiation 20030301
Title: Effect of proteasome inhibitor on cultured mesencephalic dopaminergic neurons.
Journal: Brain research 20030227
Title: Defective expression of the T-cell receptor-CD3 zeta chain in T-cell acute lymphoblastic leukaemia.
Journal: British journal of haematology 20030101
Title: The influence of epoxomicin, inhibitor of proteasomal proteolytic activity, on spermiogenesis in Chara vulgaris.
Journal: Folia histochemica et cytobiologica 20030101
Title: Conversion of PrP to a self-perpetuating PrPSc-like conformation in the cytosol.
Journal: Science (New York, N.Y.) 20021129
Title: The life cycle of the steroidogenic acute regulatory (StAR) protein: from transcription through proteolysis.
Journal: Endocrine research 20021101
Title: Role of Rpn11 metalloprotease in deubiquitination and degradation by the 26S proteasome.
Journal: Science (New York, N.Y.) 20021018
Title: Activation of Syk tyrosine kinase is required for c-Cbl-mediated ubiquitination of Fcepsilon RI and Syk in RBL cells.
Journal: The Journal of biological chemistry 20021004
Title: Ezrin turnover and cell shape changes catalyzed by proteasome in oxidatively stressed cells.
Journal: FASEB journal : official publication of the Federation of American Societies for Experimental Biology 20021001
Title: Effect of geranylgeranylaceton on cellular damage induced by proteasome inhibition in cultured spinal neurons.
Journal: Journal of neuroscience research 20020801
Title: CXCR4/CCR5 down-modulation and chemotaxis are regulated by the proteasome pathway.
Journal: The Journal of biological chemistry 20020517
Title: Transient aggregation of ubiquitinated proteins during dendritic cell maturation.
Journal: Nature 20020509
Title: Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
Journal: Human molecular genetics 20020501
Title: Probing structural determinants distal to the site of hydrolysis that control substrate specificity of the 20S proteasome.
Journal: Chemistry & biology 20020501
Title: A principal role for the proteasome in endoplasmic reticulum-associated degradation of misfolded intracellular cystic fibrosis transmembrane conductance regulator.
Journal: The Journal of biological chemistry 20020405
Title: Proteasome inhibitors: complex tools for a complex enzyme.
Journal: Current topics in microbiology and immunology 20020101
Title: The proteasome participates in degradation of mutant alpha 1-antitrypsin Z in the endoplasmic reticulum of hepatoma-derived hepatocytes.
Journal: The Journal of biological chemistry 20011130
Title: E2-induced degradation of uterine insulin receptor substrate-2: requirement for an IGF-I-stimulated, proteasome-dependent pathway.
Journal: Endocrinology 20010901
Title: Extended peptide-based inhibitors efficiently target the proteasome and reveal overlapping specificities of the catalytic beta-subunits.
Journal: Chemistry & biology 20010901
Title: Crystal structure of the 20 S proteasome:TMC-95A complex: a non-covalent proteasome inhibitor.
Journal: Journal of molecular biology 20010817
Title: Effect of proteasome inhibition on cellular oxidative damage, antioxidant defences and nitric oxide production.
Journal: Journal of neurochemistry 20010701
Title: Inhibition of proteasome activity strongly affects kiwifruit pollen germination. Involvement of the ubiquitin/proteasome pathway as a major regulator.
Journal: Plant physiology 20010701
Title: Proteasome inhibition in oxidative stress neurotoxicity: implications for heat shock proteins.
Journal: Journal of neurochemistry 20010501
Title: Lactacystin inhibits cathepsin A activity in melanoma cell lines.
Journal: Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 20010101
Title: Epoxomicin, a new antitumor agent of microbial origin.
Journal: The Journal of antibiotics 19921101
Title: Hanada M, et al. Epoxomicin, a new antitumor agent of microbial origin. J Antibiot (Tokyo). 1992 Nov;45(11):1746-52.
Title: Kim KB, et al. Proteasome inhibition by the natural products epoxomicin and dihydroeponemycin: insights into specificity and potency. Bioorg Med Chem Lett. 1999 Dec 6;9(23):3335-40.
Title: Meng L, et al. Epoxomicin, a potent and selective proteasome inhibitor, exhibits in vivo antiinflammatory activity. Proc Natl Acad Sci U S A. 1999 Aug 31;96(18):10403-8.
Title: McNaught KS, et al. Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease. Ann Neurol. 2004 Jul;56(1):149-62.
Title: Garrett IR, et al. Selective inhibitors of the osteoblast proteasome stimulate bone formation in vivo and in vitro. J Clin Invest. 2003 Jun;111(11):1771-82.
