Home Imidazoles 13395-35-2
13395-35-2,MFCD00066150
Catalog No.:AA007MKE

13395-35-2 | 5-[(3aS,4S,6aR)-2-imino-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid

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10mg
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$46.00   $32.00
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50mg
≥98%
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$112.00   $78.00
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100mg
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$199.00   $139.00
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1g
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA007MKE
Chemical Name:
5-[(3aS,4S,6aR)-2-imino-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid
CAS Number:
13395-35-2
Molecular Formula:
C10H17N3O2S
Molecular Weight:
243.3259
MDL Number:
MFCD00066150
SMILES:
NC1=N[C@@H]2[C@H](N1)[C@H](CCCCC(=O)O)SC2
Properties
Computed Properties
 
Complexity:
308  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
16  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
5  
XLogP3:
-0.2  

Downstream Synthesis Route

[1]Hofmann;Axelrod[JournalofBiologicalChemistry,1950,vol.187,p.29,31]

Literature

Title: Selective and nonselective neuronal NOS inhibitors impair cognitive function in the three panel runway and passive avoidance tasks in rats.

Journal: Pharmacology, biochemistry, and behavior 20120601

Title: Effects of hydrogen peroxide on the electrochemical decomposition of layer-by-layer thin films composed of 2-iminobiotin-labeled poly(ethyleneimine) and avidin.

Journal: Journal of colloid and interface science 20071101

Title: Gender-specific neuroprotection by 2-iminobiotin after hypoxia-ischemia in the neonatal rat via a nitric oxide independent pathway.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20070201

Title: Gender-dependent pathways of hypoxia-ischemia-induced cell death and neuroprotection in the immature P3 rat.

Journal: Developmental neuroscience 20070101

Title: Stimuli-sensitive thin films prepared by a layer-by-layer deposition of 2-iminobiotin-labeled poly(ethyleneimine) and avidin.

Journal: Langmuir : the ACS journal of surfaces and colloids 20050830

Title: Disintegration of layer-by-layer assemblies composed of 2-iminobiotin-labeled poly(ethyleneimine) and avidin.

Journal: Biomacromolecules 20050101

Title: Long-term neuroprotection with 2-iminobiotin, an inhibitor of neuronal and inducible nitric oxide synthase, after cerebral hypoxia-ischemia in neonatal rats.

Journal: Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 20050101

Title: Nitrosylation precedes caspase-3 activation and translocation of apoptosis-inducing factor in neonatal rat cerebral hypoxia-ischaemia.

Journal: Journal of neurochemistry 20040701

Title: Redox state of near infrared spectroscopy-measured cytochrome aa(3) correlates with delayed cerebral energy failure following perinatal hypoxia-ischaemia in the newborn pig.

Journal: Experimental brain research 20040501

Title: Influence of architecture on the kinetic stability of molecular assemblies.

Journal: Journal of the American Chemical Society 20040211

Title: Pharmacological interventions in the newborn piglet in the first 24 h after hypoxia-ischemia. A hemodynamic and electrophysiological perspective.

Journal: Experimental brain research 20021101

Title: Neuroprotection by selective nitric oxide synthase inhibition at 24 hours after perinatal hypoxia-ischemia.

Journal: Stroke 20020901

Title: Contributions to the binding free energy of ligands to avidin and streptavidin.

Journal: Proteins 20020501

Title: Effects of selective nitric oxide synthase inhibition on IGF-1, caspases and cytokines in a newborn piglet model of perinatal hypoxia-ischaemia.

Journal: Developmental neuroscience 20020101

Title: UV resonance Raman study of streptavidin binding of biotin and 2-iminobiotin: comparison with avidin.

Journal: Biopolymers 20010101

Title: Sup SJ, et al. 2-Iminobiotin is an inhibitor of nitric oxide synthases. Biochem Biophys Res Commun. 1994 Oct 28;204(2):962-8.

Title: Zitta K, et al. 2-Iminobiotin Superimposed on Hypothermia Protects Human Neuronal Cells from Hypoxia-Induced Cell Damage: An in Vitro Study. Front Pharmacol. 2018 Jan 11;8:971.

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Tags:13395-35-2 Molecular Formula|13395-35-2 MDL|13395-35-2 SMILES|13395-35-2 5-[(3aS,4S,6aR)-2-imino-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid