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128-62-1,MFCD00069316
Catalog No.:AA007O0S

128-62-1 | Noscapine

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10g
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$259.00   $182.00
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25g
98%
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  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA007O0S
Chemical Name:
Noscapine
CAS Number:
128-62-1
Molecular Formula:
C22H23NO7
Molecular Weight:
413.4205
MDL Number:
MFCD00069316
SMILES:
COc1ccc2c(c1OC)C(=O)OC2[C@@H]1N(C)CCc2c1c(OC)c1c(c2)OCO1
Properties
Computed Properties
 
Complexity:
647  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
8  
Rotatable Bond Count:
4  
XLogP3:
2.7  

Literature

Title: From the Cover: Does the Assessment of Nondisjunction Provide a More Sensitive Assay for the Detection of Aneugens?

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20170501

Title: Metabolic map and bioactivation of the anti-tumour drug noscapine.

Journal: British journal of pharmacology 20121101

Title: Peloruside, laulimalide, and noscapine interactions with beta-tubulin.

Journal: Pharmaceutical research 20121101

Title: Genetic and chemical components analysis of Papaver setigerum naturalized in Korea.

Journal: Forensic science international 20121010

Title: Induction of robust de novo centrosome amplification, high-grade spindle multipolarity and metaphase catastrophe: a novel chemotherapeutic approach.

Journal: Cell death & disease 20120701

Title: A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine.

Journal: Science (New York, N.Y.) 20120629

Title: Plant science. Plant gene clusters and opiates.

Journal: Science (New York, N.Y.) 20120629

Title: Albumin-binding domain conjugate for near-infrared fluorescence lymphatic imaging.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20120601

Title: A rapid method for profiling samples of illicit heroin.

Journal: Drug testing and analysis 20120601

Title: Integration of deep transcript and targeted metabolite profiles for eight cultivars of opium poppy.

Journal: Plant molecular biology 20120601

Title: Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy.

Journal: Plant physiology 20120601

Title: Noscapine induces mitochondria-mediated apoptosis in human colon cancer cells in vivo and in vitro.

Journal: Biochemical and biophysical research communications 20120511

Title: Molecular cycloencapsulation augments solubility and improves therapeutic index of brominated noscapine in prostate cancer cells.

Journal: Molecular pharmaceutics 20120507

Title: Copper(I) mediated facile synthesis of potent tubulin polymerization inhibitor, 9-amino-α-noscapine from natural α-noscapine.

Journal: Bioorganic & medicinal chemistry letters 20120415

Title: Tubulin binding, protein-bound conformation in solution, and antimitotic cellular profiling of noscapine and its derivatives.

Journal: Journal of medicinal chemistry 20120308

Title: Phytotherapeutic and naturopathic adjuvant therapies in otorhinolaryngology.

Journal: European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 20120201

Title: In silico inspired design and synthesis of a novel tubulin-binding anti-cancer drug: folate conjugated noscapine (Targetin).

Journal: Journal of computer-aided molecular design 20120201

Title: Graphene nanosheets modified glassy carbon electrode for simultaneous detection of heroine, morphine and noscapine.

Journal: Biosensors & bioelectronics 20120115

Title: Noscapinoids with anti-cancer activity against human acute lymphoblastic leukemia cells (CEM): a three dimensional chemical space pharmacophore modeling and electronic feature analysis.

Journal: Journal of molecular modeling 20120101

Title: Synthesis and evaluation of macrocyclic diarylether heptanoid natural products and their analogs.

Journal: Bioorganic & medicinal chemistry letters 20120101

Title: Exposure of consumers to morphine from poppy seeds in Hungary.

Journal: Food additives & contaminants. Part A, Chemistry, analysis, control, exposure & risk assessment 20120101

Title: Cationic albumin nanoparticles for enhanced drug delivery to treat breast cancer: preparation and in vitro assessment.

Journal: Journal of drug delivery 20120101

Title: Improving the magnetic resonance imaging contrast and detection methods with engineered magnetic nanoparticles.

Journal: Theranostics 20120101

Title: Zinc oxide nanoparticles selectively induce apoptosis in human cancer cells through reactive oxygen species.

Journal: International journal of nanomedicine 20120101

Title: Development and validation of a reversed-phase HPLC method for determination of alkaloids from Papaver somniferum L. (Papaveraceae).

Journal: Journal of AOAC International 20120101

Title: Noscapine induced apoptosis via downregulation of survivin in human neuroblastoma cells having wild type or null p53.

Journal: PloS one 20120101

Title: [Summary of NHG practice guideline 'Acute cough'].

Journal: Nederlands tijdschrift voor geneeskunde 20120101

Title: Biochemical genomics for gene discovery in benzylisoquinoline alkaloid biosynthesis in opium poppy and related species.

Journal: Methods in enzymology 20120101

Title: Noscapine inhibits tumor growth in TMZ-resistant gliomas.

Journal: Cancer letters 20111222

Title: Chronic Opium Treatment Can Differentially Induce Brain and Liver Cells Apoptosis in Diabetic and Non-diabetic Male and Female Rats.

Journal: The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology 20111201

Title: The ability of the mouse lymphoma TK assay to detect aneugens.

Journal: Mutagenesis 20111101

Title: Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy.

Journal: Plant physiology 20111101

Title: Extraction and determination of opium alkaloids in urine samples using dispersive liquid-liquid microextraction followed by high-performance liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20111015

Title: Determination of noscapine's localization and interaction with the tubulin-α/β heterodimer.

Journal: Chemical biology & drug design 20111001

Title: Rational design of novel anti-microtubule agent (9-azido-noscapine) from quantitative structure activity relationship (QSAR) evaluation of noscapinoids.

Journal: Journal of biomolecular screening 20111001

Title: Sequence capture and next generation resequencing of the MHC region highlights potential transplantation determinants in HLA identical haematopoietic stem cell transplantation.

Journal: DNA research : an international journal for rapid publication of reports on genes and genomes 20110801

Title: Second generation benzofuranone ring substituted noscapine analogs: synthesis and biological evaluation.

Journal: Biochemical pharmacology 20110715

Title: Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Journal: Journal of medicinal chemistry 20110714

Title: Long-circulating poly(ethylene glycol)-grafted gelatin nanoparticles customized for intracellular delivery of noscapine: preparation, in-vitro characterization, structure elucidation, pharmacokinetics, and cytotoxicity analyses.

Journal: Anti-cancer drugs 20110701

Title: Noscapine sensitizes chemoresistant ovarian cancer cells to cisplatin through inhibition of HIF-1α.

Journal: Cancer letters 20110601

Title: Molecular modelling and competition binding study of Br-noscapine and colchicine provide insight into noscapinoid-tubulin binding site.

Journal: Journal of molecular graphics & modelling 20110601

Title: Rational design, synthesis and biological evaluations of amino-noscapine: a high affinity tubulin-binding noscapinoid.

Journal: Journal of computer-aided molecular design 20110501

Title: A novel microtubule-modulating noscapinoid triggers apoptosis by inducing spindle multipolarity via centrosome amplification and declustering.

Journal: Cell death and differentiation 20110401

Title: Noscapine induces mitochondria-mediated apoptosis in gastric cancer cells in vitro and in vivo.

Journal: Cancer chemotherapy and pharmacology 20110301

Title: Anticancer activity of Noscapine, an opioid alkaloid in combination with Cisplatin in human non-small cell lung cancer.

Journal: Lung cancer (Amsterdam, Netherlands) 20110301

Title: Fixed drug eruption caused by noscapine.

Journal: The Journal of dermatology 20110301

Title: Enhanced noscapine delivery using uPAR-targeted optical-MR imaging trackable nanoparticles for prostate cancer therapy.

Journal: Journal of controlled release : official journal of the Controlled Release Society 20110210

Title: Antitumor activity of Noscapine in combination with Doxorubicin in triple negative breast cancer.

Journal: PloS one 20110101

Title: Pharmacological and clinical overview of cloperastine in treatment of cough.

Journal: Therapeutics and clinical risk management 20110101

Title: Decreased therapeutic effects of noscapine combined with imatinib mesylate on human glioblastoma in vitro and the effect of midkine.

Journal: Cancer cell international 20110101

Title: Mitotic and antiapoptotic effects of nanoparticles coencapsulating human VEGF and human angiopoietin-1 on vascular endothelial cells.

Journal: International journal of nanomedicine 20110101

Title: In vitro antiproliferativeactivity of Annona reticulata roots on human cancer cell lines.

Journal: Pharmacognosy research 20110101

Title: Reversible exposure of hydrophobic residues on albumin as a novel strategy for formulation of nanodelivery vehicles for taxanes.

Journal: International journal of nanomedicine 20110101

Title: Predictors of atrial fibrillation following coronary artery bypass grafting.

Journal: Clinical Medicine Insights. Cardiology 20110101

Title: Preparation and characterization of a coacervate extended-release microparticulate delivery system for Lactobacillus rhamnosus.

Journal: International journal of nanomedicine 20110101

Title: Enhanced anticancer activity of gemcitabine in combination with noscapine via antiangiogenic and apoptotic pathway against non-small cell lung cancer.

Journal: PloS one 20110101

Title: Cell death signaling and anticancer therapy.

Journal: Frontiers in oncology 20110101

Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.

Journal: Bioorganic & medicinal chemistry letters 20101101

Title: Clinically significant CYP2C inhibition by noscapine but not by glucosamine.

Journal: Clinical pharmacology and therapeutics 20100901

Title: Evaluation of ligand-selector interaction from effective diffusion coefficient.

Journal: Analytical chemistry 20100701

Title: Efficacy and safety of modified sequential three-step empirical therapy for chronic cough.

Journal: Respirology (Carlton, Vic.) 20100701

Title: Induction of reactive oxygen species-mediated autophagy by a novel microtubule-modulating agent.

Journal: The Journal of biological chemistry 20100611

Title: A novel microtubule-modulating agent induces mitochondrially driven caspase-dependent apoptosis via mitotic checkpoint activation in human prostate cancer cells.

Journal: European journal of cancer (Oxford, England : 1990) 20100601

Title: Noscapine, a benzylisoquinoline alkaloid, sensitizes leukemic cells to chemotherapeutic agents and cytokines by modulating the NF-kappaB signaling pathway.

Journal: Cancer research 20100415

Title: Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy.

Journal: Nature chemical biology 20100401

Title: (3R*,5'S*)-6,7-Dimeth-oxy-3-(4'-meth-oxy-6'-methyl-5',6',7',8'-tetra-hydro-1,3-dioxolo[4,5-g]isoquinolin-5'-yl)isobenzofuran-1(3H)-one (racemic α-noscapine).

Journal: Acta crystallographica. Section E, Structure reports online 20100301

Title: Inclusion complexes of noscapine in beta-cyclodextrin offer better solubility and improved pharmacokinetics.

Journal: Cancer chemotherapy and pharmacology 20100201

Title: Simultaneous chemiluminescence determination of thebaine and noscapine using support vector machine regression.

Journal: Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 20100201

Title: Time-dependent inhibition (TDI) of CYP3A4 and CYP2C9 by noscapine potentially explains clinical noscapine-warfarin interaction.

Journal: British journal of clinical pharmacology 20100201

Title: Prophylactic noscapine therapy inhibits human prostate cancer progression and metastasis in a mouse model.

Journal: Anticancer research 20100201

Title: Simultaneous liquid chromatography-mass spectrometry quantification of urinary opiates, cocaine, and metabolites in opiate-dependent pregnant women in methadone-maintenance treatment.

Journal: Journal of analytical toxicology 20100101

Title: Potent anti-inflammatory activity of novel microtubule-modulating brominated noscapine analogs.

Journal: PloS one 20100101

Title: BIAdb: a curated database of benzylisoquinoline alkaloids.

Journal: BMC pharmacology 20100101

Title: Radiolabeling, biodistribution and gamma scintigraphy of noscapine hydrochloride in normal and polycystic ovary induced rats.

Journal: Journal of ovarian research 20100101

Title: Griseofulvin stabilizes microtubule dynamics, activates p53 and inhibits the proliferation of MCF-7 cells synergistically with vinblastine.

Journal: BMC cancer 20100101

Title: Validation of the ERS standard citric acid cough challenge in healthy adult volunteers.

Journal: Cough (London, England) 20100101

Title: Human serum albumin nanoparticles as an efficient noscapine drug delivery system for potential use in breast cancer: preparation and in vitro analysis.

Journal: International journal of nanomedicine 20100101

Title: Xenobiotic exposure and autoimmune hepatitis.

Journal: Hepatitis research and treatment 20100101

Title: Relevance of an opioid, noscapine in reducing cystogeneses in rat experimental model of polycystic ovary syndrome.

Journal: Journal of endocrinological investigation 20091101

Title: Recent patents reveal microtubules as persistent promising target for novel drug development for cancers.

Journal: Recent patents on anti-infective drug discovery 20091101

Title: General unknown screening procedure for the characterization of human drug metabolites in forensic toxicology: applications and constraints.

Journal: Journal of separation science 20090901

Title: Validated stability-indicating TLC method for the determination of noscapine.

Journal: Drug testing and analysis 20090701

Title: A validated hybrid quadrupole linear ion-trap LC-MS method for the analysis of morphine and morphine glucuronides applied to opiate deaths.

Journal: Forensic science international 20090530

Title: [Pharmacological treatment of acute cough].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090514

Title: Validation of a liquid chromatography-tandem mass spectrometric assay for the quantitative determination of hydrastine and berberine in human serum.

Journal: Journal of pharmaceutical and biomedical analysis 20090501

Title: 9-bromonoscapine-induced mitotic arrest of cigarette smoke condensate-transformed breast epithelial cells.

Journal: Journal of cellular biochemistry 20090415

Title: Adulterant profile of illicit street heroin and reduction of its precipitated physical dependence withdrawal syndrome by extracts of St John's wort (Hypericum perforatum).

Journal: Phytotherapy research : PTR 20090401

Title: Capillary zone electrophoresis with diode-array detection for analysis of local anaesthetics and opium alkaloids in urine samples.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20090315

Title: [Noscapine and warfarin--a potentially dangerous interaction].

Journal: Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke 20090312

Title: 2,3-Disubstituted-1,4-naphthoquinones, 12H-benzo[b]phenothiazine-6,11-diones and related compounds: synthesis and biological evaluation as potential antiproliferative and antifungal agents.

Journal: European journal of medicinal chemistry 20090301

Title: Tubulin-interactive natural products as anticancer agents.

Journal: Journal of natural products 20090301

Title: Simultaneous determination of codeine and noscapine by flow-injection chemiluminescence method using N-PLS regression.

Journal: Journal of pharmaceutical and biomedical analysis 20090220

Title: The anti-cancer activity of noscapine: a review.

Journal: Recent patents on anti-cancer drug discovery 20090101

Title: EM011 activates a survivin-dependent apoptotic program in human non-small cell lung cancer cells.

Journal: Molecular cancer 20090101

Title: Electrochemical sensors based on carbon nanotubes.

Journal: Sensors (Basel, Switzerland) 20090101

Title: Antitumor activity of noscapine in human non-small cell lung cancer xenograft model.

Journal: Cancer chemotherapy and pharmacology 20081201

Title: Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.

Journal: Archives of toxicology 20081201

Title: Antiangiogenic effects of noscapine enhance radioresponse for GL261 tumors.

Journal: International journal of radiation oncology, biology, physics 20080801

Title: Effect of noscapine and vincristine combination on demyelination and cell proliferation in vitro.

Journal: Leukemia & lymphoma 20080801

Title: Noscapine induces apoptosis in human glioma cells by an apoptosis-inducing factor-dependent pathway.

Journal: Anti-cancer drugs 20080701

Title: Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Journal: Journal of medicinal chemistry 20080612

Title: Applicability of ultra-performance liquid chromatography-tandem mass spectrometry for heroin profiling.

Journal: Journal of chromatography. A 20080425

Title: Persistence of DNA threads in human anaphase cells suggests late completion of sister chromatid decatenation.

Journal: Chromosoma 20080401

Title: Warfarin-noscapine interaction: a series of four case reports.

Journal: The Annals of pharmacotherapy 20080301

Title: Noscapine may increase the effect of warfarin.

Journal: British journal of clinical pharmacology 20080201

Title: Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.

Journal: Journal of medicinal chemistry 20080124

Title: Quantitative 1H NMR metabolomics reveals extensive metabolic reprogramming of primary and secondary metabolism in elicitor-treated opium poppy cell cultures.

Journal: BMC plant biology 20080101

Title: Role of CAP350 in centriolar tubule stability and centriole assembly.

Journal: PloS one 20080101

Title: Noscapine inhibits human prostate cancer progression and metastasis in a mouse model.

Journal: Anticancer research 20080101

Title: Differentiation of opium and poppy straw using capillary electrophoresis and pattern recognition techniques.

Journal: Analytica chimica acta 20071212

Title: Simultaneous voltammetric determination of morphine and noscapine by adsorptive differential pulse stripping method and least-squares support vector machines.

Journal: Talanta 20071130

Title: Preclinical pharmacokinetics and bioavailability of noscapine, a tubulin-binding anticancer agent.

Journal: Cancer chemotherapy and pharmacology 20071101

Title: Apoptotic pathway induced by noscapine in human myelogenous leukemic cells.

Journal: Anti-cancer drugs 20071101

Title: Separation and determination of five major opium alkaloids with mixed mode of hydrophilic/cation-exchange monolith by pressurized capillary electrochromatography.

Journal: Journal of separation science 20071101

Title: Fatal poisoning by alcohol and heroin.

Journal: Arhiv za higijenu rada i toksikologiju 20070901

Title: Optimum conditions for detecting hepatic micronuclei caused by numerical chromosome aberration inducers in mice.

Journal: Mutation research 20070815

Title: A simple and rapid flow-injection chemiluminescence method for the determination of noscapine with Ru(phen)3(2+)-Ce(IV) system.

Journal: Annali di chimica 20070801

Title: p53 and p21 determine the sensitivity of noscapine-induced apoptosis in colon cancer cells.

Journal: Cancer research 20070415

Title: Validation of meconin as a marker for illicit opiate use.

Journal: Journal of analytical toxicology 20070301

Title: Synthesis and biological evaluation of a cyclic ether fluorinated noscapine analog.

Journal: Bioorganic & medicinal chemistry 20061215

Title: Synthesis and in vitro cytotoxicity of haloderivatives of noscapine.

Journal: Bioorganic & medicinal chemistry 20061001

Title: Treatment of hormone-refractory breast cancer: apoptosis and regression of human tumors implanted in mice.

Journal: Molecular cancer therapeutics 20060901

Title: Synthesis of microtubule-interfering halogenated noscapine analogs that perturb mitosis in cancer cells followed by cell death.

Journal: Biochemical pharmacology 20060814

Title: The significance of putative urinary markers of illicit heroin use after consumption of poppy seed products.

Journal: Therapeutic drug monitoring 20060801

Title: Quantitative analysis of morphine and noscapine using corona discharge ion mobility spectrometry with ammonia reagent gas.

Journal: Talanta 20060615

Title: Development of a novel nitro-derivative of noscapine for the potential treatment of drug-resistant ovarian cancer and T-cell lymphoma.

Journal: Molecular pharmacology 20060601

Title: Evaluation of the HER2/neu-derived peptide GP2 for use in a peptide-based breast cancer vaccine trial.

Journal: Cancer 20060601

Title: Coated wire potentiometric detection for capillary electrophoresis studied using organic amines, drugs, and biogenic amines.

Journal: Analytical chemistry 20060601

Title: Noscapine inhibits hypoxia-mediated HIF-1alpha expression andangiogenesis in vitro: a novel function for an old drug.

Journal: International journal of oncology 20060501

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Noscapine and diltiazem augment taxol and radiation-induced S-phase arrest and clonogenic death of C6 glioma in vitro.

Journal: Surgical neurology 20060501

Title: Rational design of the microtubule-targeting anti-breast cancer drug EM015.

Journal: Cancer research 20060401

Title: Drug-resistant T-lymphoid tumors undergo apoptosis selectively in response to an antimicrotubule agent, EM011.

Journal: Blood 20060315

Title: Interaction of papaverine with the enalapril-induced cough in guinea pig.

Journal: Acta physiologica Hungarica 20060301

Title: Atmospheric pressure ionisation mass spectrometric fragmentation pathways of noscapine and papaverine revealed by multistage mass spectrometry and in-source deuterium labelling.

Journal: Rapid communications in mass spectrometry : RCM 20060101

Title: Anxiolytic effect of noscapine in mice.

Journal: Pharmacological reports : PR 20060101

Title: Validation of techniques to detect illicit heroin use in patients prescribed pharmaceutical heroin for the management of opioid dependence.

Journal: Addiction (Abingdon, England) 20051201

Title: Identification of novel and improved antimitotic agents derived from noscapine.

Journal: Journal of medicinal chemistry 20051117

Title: A rapid and reliable solid-phase extraction method for high-performance liquid chromatographic analysis of opium alkaloids from papaver plants.

Journal: Chemical & pharmaceutical bulletin 20051101

Title: [Analysis of two year heroin seizures in the Liege area].

Journal: Revue medicale de Liege 20050901

Title: Noscapine suppresses angiotensin converting enzyme inhibitors-induced cough.

Journal: Nephrology (Carlton, Vic.) 20050801

Title: Principal opium alkaloids as possible biochemical markers for the source identification of Indian opium.

Journal: Journal of separation science 20050801

Title: Synthesis and radioligand binding studies of C-5- and C-8-substituted 1-(3,4-dimethoxybenzyl)-2,2-dimethyl-1,2,3,4-tetrahydroisoquinoliniums as SK channel blockers related to N-methyl-laudanosine and N-methyl-noscapine.

Journal: Journal of medicinal chemistry 20050728

Title: Automated multiple development thin-layer chromatography for separation of opiate alkaloids and derivatives.

Journal: Journal of chromatography. A 20050708

Title: Simultaneous determination of methylephedrine and noscapine in human plasma by liquid chromatography-tandem mass spectrometry.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20050625

Title: Comparative qualitative and quantitative determination of alkaloids in narcotic and condiment Papaver somniferum cultivars.

Journal: Journal of natural products 20050501

Title: Discovery of S-phase arresting agents derived from noscapine.

Journal: Journal of medicinal chemistry 20050421

Title: Yeast DEL assay detects clastogens.

Journal: Mutation research 20050404

Title: Simultaneous determination of ingredients in a cold medicine by cyclodextrin-modified microemulsion electrokinetic chromatography.

Journal: Journal of pharmaceutical and biomedical analysis 20050309

Title: Development and validation of a capillary electrophoresis method for the determination of codeine, diphenhydramine, ephedrine and noscapine in pharmaceuticals.

Journal: Farmaco (Societa chimica italiana : 1989) 20050101

Title: Targeting microtubules for cancer chemotherapy.

Journal: Current medicinal chemistry. Anti-cancer agents 20050101

Title: PIKE GTPase signaling and function.

Journal: International journal of biological sciences 20050101

Title: Thin-layer chromatography-densitometry and liquid chromatography analysis of alkaloids in leaves of Papaver somniferum under stress conditions.

Journal: Journal of AOAC International 20050101

Title: Validated assay for the determination of markers of illicit heroin in urine samples for the control of patients in a heroin prescription program.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20041105

Title: Electrophysiological characterization of the SK channel blockers methyl-laudanosine and methyl-noscapine in cell lines and rat brain slices.

Journal: British journal of pharmacology 20041101

Title: Noscapine crosses the blood-brain barrier and inhibits glioblastoma growth.

Journal: Clinical cancer research : an official journal of the American Association for Cancer Research 20040801

Title: Modulatory influence of noscapine on the ethanol-altered hepatic biotransformation system enzymes, glutathione content and lipid peroxidation in vivo in rats.

Journal: European journal of drug metabolism and pharmacokinetics 20040101

Title: A preliminary report on the application of noscapine in the treatment of stroke.

Journal: European journal of clinical pharmacology 20031101

Title: HPLC determination of aminophylline, methoxyphenamine hydrochloride, noscapine and chlorphenamine maleate in compound dosage forms with an aqueous-organic mobile phase.

Journal: Journal of pharmaceutical and biomedical analysis 20030915

Title: Measuring the mitotic index in chemically-treated human lymphocyte cultures by flow cytometry.

Journal: Mutation research 20030606

Title: Liquid chromatographic-atmospheric pressure chemical ionization mass spectrometric analysis of opiates and metabolites in rat urine after inhalation of opium.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20030605

Title: Noscapine hydrochloride-induced numerical aberrations in cultured human lymphocytes: a comparison of FISH detection methods and multiple end-points.

Journal: Mutagenesis 20030501

Title: Application of capillary zone electrophoresis in the separation and determination of the principal gum opium alkaloids.

Journal: Electrophoresis 20030501

Title: Brominated derivatives of noscapine are potent microtubule-interfering agents that perturb mitosis and inhibit cell proliferation.

Journal: Molecular pharmacology 20030401

Title: Use of dynamically coated capillaries with added cyclodextrins for the analysis of opium using capillary electrophoresis.

Journal: Journal of chromatography. A 20030110

Title: Interaction of noscapine with the bradykinin mediation of the cough response.

Journal: Acta physiologica Hungarica 20030101

Title: Reduction of the prenatal hypoxic-ischemic brain edema with noscapine.

Journal: Acta physiologica Hungarica 20030101

Title: [Influence of fertilizers on yield and yield components of opium from Papaver somniferum Linn].

Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20030101

Title: Enhancing the in vitro and in vivo detection of aneuploidy by fluorescence in situ hybridization with the use of bromodeoxyuridine as a proliferation marker.

Journal: Mutation research 20021126

Title: Paclitaxel-resistant human ovarian cancer cells undergo c-Jun NH2-terminal kinase-mediated apoptosis in response to noscapine.

Journal: The Journal of biological chemistry 20021018

Title: Noscapine alters microtubule dynamics in living cells and inhibits the progression of melanoma.

Journal: Cancer research 20020715

Title: Novel substituted methylenedioxy lignan suppresses proliferation of cancer cells by inhibiting telomerase and activation of c-myc and caspases leading to apoptosis.

Journal: British journal of cancer 20020701

Title: GC/MS determination of pyrolysis products from diacetylmorphine and adulterants of street heroin samples.

Journal: Journal of forensic sciences 20020701

Title: Minor alteration of microtubule dynamics causes loss of tension across kinetochore pairs and activates the spindle checkpoint.

Journal: The Journal of biological chemistry 20020510

Title: Sustained ER Ca2+ depletion suppresses protein synthesis and induces activation-enhanced cell death in mast cells.

Journal: The Journal of biological chemistry 20020419

Title: Mass spectral studies on aryl-substituted N-carbamoyl/N-thiocarbamoyl narcotine and related compounds.

Journal: Rapid communications in mass spectrometry : RCM 20020101

Title: Sustained activation of p34(cdc2) is required for noscapine-induced apoptosis.

Journal: The Journal of biological chemistry 20011214

Title: Detection of non-prescription heroin markers in urine with liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.

Journal: Journal of analytical toxicology 20010901

Title: Characterization of an unknown component in Noscapine using liquid chromatography-mass spectrometry and proton nuclear magnetic resonance spectroscopy.

Journal: Journal of chromatography. A 20010824

Title: Peripheral T-cell lymphoma with aberrant expression of CD79a and CD20: a diagnostic pitfall.

Journal: Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 20010201

Title: Isoquinoline alkaloid production by transformed cultures of Papaver somniferum.

Journal: Kokuritsu Iyakuhin Shokuhin Eisei Kenkyujo hokoku = Bulletin of National Institute of Health Sciences 20010101

Title: Efffect of noscapine, the antitussive opioid alkaloid, on bradykinin-induced smooth muscle contraction in the isolated ileum of the guinea-pig.

Journal: Acta physiologica Hungarica 20010101

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Tags:128-62-1 Molecular Formula|128-62-1 MDL|128-62-1 SMILES|128-62-1 Noscapine