[1]Hayashi,Kazuya;Takahata,Masahiro;Kawamura,Yasuhito;Todo,Yozo[Arzneimittel-Forschung/DrugResearch,2002,vol.52,#12,p.903-913]
[1]Peek,James;Koirala,Bimal;Brady,SeanF.[BioorganicandMedicinalChemistryLetters,2022,vol.57]
[2]Peek,James;Koirala,Bimal;Brady,SeanF.[BioorganicandMedicinalChemistryLetters,2022,vol.57]
Title: In vitro antichlamydial activity of garenoxacin against Chlamydia trachomatis.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20120801
Title: Inhibitory activity of garenoxacin against DNA gyrase of Mycoplasma pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20120801
Title: In vitro pharmacodynamic evaluation of garenoxacin against quinolone-resistant Streptococcus pneumoniae.
Journal: International journal of antimicrobial agents 20120201
Title: Optimal dose finding of garenoxacin based on population pharmacokinetics/pharmacodynamics and Monte Carlo simulation.
Journal: European journal of clinical pharmacology 20120101
Title: Anaphylaxis due to intravenous levofloxacin with tolerance to garenoxacin.
Journal: Internal medicine (Tokyo, Japan) 20120101
Title: Anti-inflammatory effects of garenoxacin on IL-8 production and ERK1/2 activation induced by lipopolysaccharides in A549 and THP-1 cells.
Journal: European journal of pharmacology 20111001
Title: In vitro and in vivo antibacterial activities of garenoxacin against group G Streptococcus dysgalactiae subsp. equisimilis.
Journal: International journal of antimicrobial agents 20110901
Title: Pulmonary nocardiosis caused by Nocardia exalbida complicating Pneumocystis pneumonia in an HIV-infected patient.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110801
Title: Garenoxacin-induced increase of CD11b expression on human polymorphonuclear neutrophils does not affect phagocytosis and killing of Staphylococcus aureus.
Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20110401
Title: [Mutant prevention concentrations of garenoxacin against Streptococcus pneumoniae isolates from otorhinolaryngological infections].
Journal: The Japanese journal of antibiotics 20100801
Title: Pharmacokinetics of garenoxacin in elderly patients with respiratory tract infections.
Journal: International journal of antimicrobial agents 20100601
Title: Torsades de Pointes induced by a combination of garenoxacin and disopyramide and other cytochrome P450, family 3, subfamily A polypeptide-4-influencing drugs during hypokalemia due to licorice.
Journal: Clinical and experimental nephrology 20100401
Title: Design, synthesis and biological evaluations of novel 7-[3-(1-aminocycloalkyl)pyrrolidin-1-yl]-6-desfluoro-8-methoxyquinolones with potent antibacterial activity against multi-drug resistant Gram-positive bacteria.
Journal: Bioorganic & medicinal chemistry 20091001
Title: [Antimicrobial susceptibility surveillance of recent isolates from otorhinolaryngological infections to garenoxacin and other antimicrobial drugs].
Journal: The Japanese journal of antibiotics 20090401
Title: Quinolones with enhanced bactericidal activity induce autolysis in Streptococcus pneumoniae.
Journal: Chemotherapy 20090101
Title: Clinical studies of garenoxacin.
Journal: International journal of antimicrobial agents 20081201
Title: Comparative pharmacodynamics of garenoxacin, gemifloxacin, and moxifloxacin in community-acquired pneumonia caused by Streptococcus pneumoniae: a Monte Carlo simulation analysis.
Journal: Clinical therapeutics 20071201
Title: Potency and spectrum of garenoxacin tested against an international collection of skin and soft tissue infection pathogens: report from the SENTRY antimicrobial surveillance program (1999-2004).
Journal: Diagnostic microbiology and infectious disease 20070501
Title: In vitro activity of garenoxacin tested against a worldwide collection of ciprofloxacin-susceptible and ciprofloxacin-resistant Enterobacteriaceae strains (1999-2004).
Journal: Diagnostic microbiology and infectious disease 20070501
Title: The effect of omeprazole on the bioavailability and safety of garenoxacin in healthy volunteers.
Journal: Journal of clinical pharmacology 20070501
Title: Activity of garenoxacin, an investigational des-F(6)-quinolone, tested against pathogens from community-acquired respiratory tract infections, including those with elevated or resistant-level fluoroquinolone MIC values.
Journal: Diagnostic microbiology and infectious disease 20070501
Title: Garenoxacin activity against isolates form patients hospitalized with community-acquired pneumonia and multidrug-resistant Streptococcus pneumoniae.
Journal: Diagnostic microbiology and infectious disease 20070501
Title: Simultaneous determination and validation of antimicrobials in plasma and tissue of actinomycetoma by high-performance liquid chromatography with diode array and fluorescence detection.
Journal: Journal of pharmaceutical and biomedical analysis 20070411
Title: Garenoxacin pharmacokinetics in subjects with renal impairment.
Journal: Current medical research and opinion 20070301
Title: [In-vitro and in-vivo activities of moxifloxacin and garenoxacin against Mycobacterium leprae].
Journal: Nihon Hansenbyo Gakkai zasshi = Japanese journal of leprosy : official organ of the Japanese Leprosy Association 20070201
Title: 3-aminoquinazolinediones as a new class of antibacterial agents demonstrating excellent antibacterial activity against wild-type and multidrug resistant organisms.
Journal: Journal of medicinal chemistry 20061102
Title: Pharmacodynamic activity of garenoxacin against ciprofloxacin-resistant Streptococcus pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20060701
Title: Intravitreal toxicity of garenoxacin.
Journal: Retina (Philadelphia, Pa.) 20060201
Title: Comparative in vitro antimicrobial activity of a novel quinolone, garenoxacin, against aerobic and anaerobic microbial isolates recovered from general, vascular, cardiothoracic and otolaryngologic surgical patients.
Journal: The Journal of antimicrobial chemotherapy 20051101
Title: In vitro susceptibility of Mycobacterium tuberculosis clinical isolates to garenoxacin and DA-7867.
Journal: Antimicrobial agents and chemotherapy 20051001
Title: Comparison of the minimum inhibitory, mutant prevention and minimum bactericidal concentrations of ciprofloxacin, levofloxacin and garenoxacin against enteric Gram-negative urinary tract infection pathogens.
Journal: Journal of chemotherapy (Florence, Italy) 20051001
Title: Comparative activity of quinolones (ciprofloxacin, levofloxacin, moxifloxacin and garenoxacin) against extracellular and intracellular infection by Listeria monocytogenes and Staphylococcus aureus in J774 macrophages.
Journal: The Journal of antimicrobial chemotherapy 20050401
Title: Bactericidal activity of garenoxacin tested by kill-curve methodology against wild type and QRDR mutant strains of Streptococcus pneumoniae.
Journal: Diagnostic microbiology and infectious disease 20041101
Title: Mycobacterium tuberculosis DNA gyrase: interaction with quinolones and correlation with antimycobacterial drug activity.
Journal: Antimicrobial agents and chemotherapy 20040401
Title: Concentrations of the des-F(6)-quinolone garenoxacin in plasma and joint cartilage of immature rats.
Journal: Archives of toxicology 20040201
Title: Comparisons of the in vitro susceptibility testing results for garenoxacin using six different national methods: report from the garenoxacin international bridging study.
Journal: The Journal of antimicrobial chemotherapy 20040201
Title: Comparative activity of garenoxacin and other agents by susceptibility and time-kill testing against Staphylococcus aureus, Streptococcus pyogenes and respiratory pathogens.
Journal: The Journal of antimicrobial chemotherapy 20031101
Title: Metabolism and disposition of novel des-fluoro quinolone garenoxacin in experimental animals and an interspecies scaling of pharmacokinetic parameters.
Journal: Drug metabolism and disposition: the biological fate of chemicals 20031101
Title: Accumulation of garenoxacin by Bacteroides fragilis compared with that of five fluoroquinolones.
Journal: The Journal of antimicrobial chemotherapy 20031001
Title: [Comparative in vitro activity of garenoxacin (BMS-284756). Sentry program, Spain (1999-2000)].
Journal: Enfermedades infecciosas y microbiologia clinica 20031001
Title: Ultrastructural changes induced by the des-F(6)-quinolone garenoxacin (BMS-284756) and two fluoroquinolones in Achilles tendon from immature rats.
Journal: Archives of toxicology 20030901
Title: In vitro activity of garenoxacin against recent clinical isolates of Chlamydia pneumoniae.
Journal: International journal of antimicrobial agents 20030601
Title: Re-evaluation of quality control guidelines for gatifloxacin and garenoxacin (BMS284756) when susceptibility testing Haemophilus influenzae and Streptococcus pneumoniae.
Journal: Diagnostic microbiology and infectious disease 20030601
Title: Comparative activity of garenoxacin (BMS 284756), a novel desfluoroquinolone, tested against 8,331 isolates from community-acquired respiratory tract infections: North American results from the SENTRY Antimicrobial Surveillance Program (1999-2001).
Journal: Diagnostic microbiology and infectious disease 20030401
Title: Pharmacological evaluation of garenoxacin, a novel des-F(6)-quinolone antimicrobial agent: effects on the central nervous system.
Journal: The Journal of toxicological sciences 20030201
Title: Garenoxacin (BMS-284756) and moxifloxacin in experimental meningitis caused by vancomycin-tolerant pneumococci.
Journal: Antimicrobial agents and chemotherapy 20030101
Title: Antimicrobial activity of a novel des-fluoro (6) quinolone, garenoxacin (BMS-284756), compared to other quinolones, against clinical isolates from cancer patients.
Journal: Diagnostic microbiology and infectious disease 20021001
Title: Intra-abdominal anaerobic infections: bacteriology and therapeutic potential of newer antimicrobial carbapenem, fluoroquinolone, and desfluoroquinolone therapeutic agents.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 20020901
Title: Comparative in vitro activity of garenoxacin against Chlamydia spp.
Journal: The Journal of antimicrobial chemotherapy 20020901
Title: Geographic variations in garenoxacin (BMS284756) activity tested against pathogens associated with skin and soft tissue infections: report from the SENTRY Antimicrobial Surveillance Program (2000).
Journal: Diagnostic microbiology and infectious disease 20020801
Title: Comparative articular toxicity of garenoxacin, a novel quinolone antimicrobial agent, in juvenile beagle dogs.
Journal: The Journal of toxicological sciences 20020801
Title: Synergistic activity of the novel des-fluoro(6) quinolone, garenoxacin (BMS-284756), in combination with other antimicrobial agents against Pseudomonas aeruginosa and related species.
Journal: International journal of antimicrobial agents 20020701
Title: Comparative antimicrobial spectrum and activity of the desfluoroquinolone BMS284756 (T-3811) tested against non-fermentative Gram-negative bacilli.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20020601
Title: Single- and multistep selection study of the antipneumococcal activity of BMS-284756 compared to ciprofloxacin, levofloxacin, trovafloxacin and moxifloxacin.
Journal: Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 20020601
Title: BMS284756 (formerly T-3811, a des-fluoroquinolone) potency and spectrum tested against over 10,000 bacterial bloodstream infection isolates from the SENTRY antimicrobial surveillance programme (2000).
Journal: The Journal of antimicrobial chemotherapy 20020501
Title: In vitro antibacterial activities of DQ-113, a potent quinolone, against clinical isolates.
Journal: Antimicrobial agents and chemotherapy 20020301
Title: Increased in vitro activity of the novel des-fluoro(6) quinolone BMS-284756 against genetically defined clinical isolates of Staphylococcus aureus.
Journal: The Journal of antimicrobial chemotherapy 20020201
Title: Antimicrobial resistance trends in community-acquired respiratory tract pathogens in the Western Pacific Region and South Africa: report from the SENTRY antimicrobial surveillance program, (1998-1999) including an in vitro evaluation of BMS284756.
Journal: International journal of antimicrobial agents 20020201
Title: Comparative antimicrobial spectrum and activity of BMS284756 (T-3811; a desfluoroquinolone) tested against an international collection of staphylococci and enterococci, including in vitro test development and intermethod comparisons.
Journal: Journal of chemotherapy (Florence, Italy) 20020201
Title: The in vitro activity of BMS-284756, a new des-fluorinated quinolone.
Journal: The Journal of antimicrobial chemotherapy 20020101
Title: Comparison of the bactericidal activities and post-antibiotic effects of the Des-F(6)-quinolone BMS-284756, levofloxacin, and ciprofloxacin against methicillin-susceptible and methicillin-resistant Staphylococcus aureus.
Journal: European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 20020101
Title: Synthesis, antibacterial activity, and toxicity of 7-(isoindolin-5-yl)-4-oxoquinoline-3-carboxylic acids. Discovery of the novel des-F(6)-quinolone antibacterial agent garenoxacin (T-3811 or BMS-284756).
Journal: Arzneimittel-Forschung 20020101
Title: Determination of BMS-284756, a new quinolone, in mouse serum by high-performance liquid chromatography with fluorescence detection.
Journal: Journal of chromatography. B, Biomedical sciences and applications 20011205
Title: BMS-284756 (T-3811ME) a new fluoroquinolone: in vitro activity against Legionella, efficacy in a guinea pig model of L. pneumophila pneumonia and pharmacokinetics in guinea pigs.
Journal: The Journal of antimicrobial chemotherapy 20011101
Title: Activity of the novel des-fluoro(6) quinolone BMS-284756 against methicillin-susceptible and -resistant staphylococci.
Journal: The Journal of antimicrobial chemotherapy 20011101
Title: Antimicrobial activity of BMS 284756 (T-3811) against Neisseria gonorrhoeae tested by three methods.
Journal: International journal of antimicrobial agents 20011101
Title: Comparison of the in vitro activities of BMS-284756 and four fluoroquinolones against Streptococcus pneumoniae.
Journal: The Journal of antimicrobial chemotherapy 20010901
Title: The inhibition and selectivity of bacterial topoisomerases by BMS-284756 and its analogues.
Journal: The Journal of antimicrobial chemotherapy 20010801
Title: Comparative antimicrobial spectrum and activity of BMS284756 (T-3811, a desfluoroquinolone) tested against 656 Enterobacteriaceae, including preliminary in vitro susceptibility test comparisons and development.
Journal: International journal of antimicrobial agents 20010801
Title: Comparative killing kinetics of the novel des-fluoro(6) quinolone BMS-284756, fluoroquinolones, vancomycin and beta-lactams.
Journal: International journal of antimicrobial agents 20010701
Title: Activity of BMS284756 against 2,681 recent clinical isolates of Haemophilus influenzae and Moraxella catarrhalis: Report from The SENTRY Antimicrobial Surveillance Program (2000) in Europe, Canada and the United States.
Journal: Diagnostic microbiology and infectious disease 20010401
Title: Activity and spectrum of BMS 284756, a new des-F (6) quinolone, tested against strains of ciprofloxacin-resistant Gram-positive cocci.
Journal: Diagnostic microbiology and infectious disease 20010201
Title: Activity of BMS284756 (T-3811) tested against anaerobic bacteria, Campylobacter jejuni, Helicobacter pylori and Legionella spp.
Journal: Diagnostic microbiology and infectious disease 20010101
Title: In vitro susceptibility study of BMS-284756 against Legionella species.
Journal: Diagnostic microbiology and infectious disease 20010101
Title: Antibacterial spectrum of a novel des-fluoro(6) quinolone, BMS-284756.
Journal: Antimicrobial agents and chemotherapy 20001201
Title: In vitro and in vivo antimicrobial activities of T-3811ME, a novel des-F(6)-quinolone.
Journal: Antimicrobial agents and chemotherapy 19990501