Home Fluorides 110234-68-9
110234-68-9,MFCD11099951
Catalog No.:AA007VCA

110234-68-9 | 4,4,4-Trifluoro-3-oxobutanenitrile

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250mg
95%
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$552.00   $387.00
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1g
95%
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$1,306.00   $914.00
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA007VCA
Chemical Name:
4,4,4-Trifluoro-3-oxobutanenitrile
CAS Number:
110234-68-9
Molecular Formula:
C4H2F3NO
Molecular Weight:
137.0600
MDL Number:
MFCD11099951
SMILES:
N#CCC(=O)C(F)(F)F
Properties
Computed Properties
 
Complexity:
162  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
9  
Hydrogen Bond Acceptor Count:
5  
Rotatable Bond Count:
1  
XLogP3:
1  

Downstream Synthesis Route

[1]JournalofMedicinalChemistry,2016,vol.59,p.8293-8305

[2]Patent:WO2008/33999,2008,A2.Locationinpatent:Page/Pagecolumn86-87

[1]Patent:JP2017/141196,2017,A.Locationinpatent:Paragraph0072-0074

[2]Patent:WO2005/49033,2005,A1.Locationinpatent:Page/Pagecolumn97

[3]Patent:WO2008/63671,2008,A2.Locationinpatent:Page/Pagecolumn133-134

[4]JournalofMedicinalChemistry,2017,vol.60,p.5099-5119

[1]CurrentPatentAssignee:XIEYOU-US5405829,1995,A

[1]Patent:US2009/264434,2009,A1.Locationinpatent:Page/Pagecolumn44

[1]Patent:WO2011/124930,2011,A1.Locationinpatent:Page/Pagecolumn54-55

Literature

Title: Determination and characterization of cysteine, glutathione and phytochelatins (PC₂₋₆) in Lolium perenne L. exposed to Cd stress under ambient and elevated carbon dioxide using HPLC with fluorescence detection.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20110615

Title: Mechanism of heparin acceleration of tissue inhibitor of metalloproteases-1 (TIMP-1) degradation by the human neutrophil elastase.

Journal: PloS one 20110101

Title: Synthesis and optimization of the labeling procedure of 99mTc-HYNIC-interleukin-2 for in vivo imaging of activated T lymphocytes.

Journal: Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 20101001

Title: Liquid chromatographic analysis of Hg(II) binding by thiol-rich peptides using both UV-vis and electrochemical detection.

Journal: Journal of chromatography. A 20090925

Title: Integrated proteomic analysis of human cancer cells and plasma from tumor bearing mice for ovarian cancer biomarker discovery.

Journal: PloS one 20090101

Title: A mouse to human search for plasma proteome changes associated with pancreatic tumor development.

Journal: PLoS medicine 20080601

Title: Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro.

Journal: Journal of inflammation (London, England) 20080101

Title: SELDI-TOF-MS determination of hepcidin in clinical samples using stable isotope labelled hepcidin as an internal standard.

Journal: Proteome science 20080101

Title: A rapid HPLC method for simultaneous determination of tretinoin and isotretinoin in dermatological formulations.

Journal: Journal of pharmaceutical and biomedical analysis 20070219

Title: The characterization of amphibian nucleoplasmins yields new insight into their role in sperm chromatin remodeling.

Journal: BMC genomics 20060101

Title: Optimum separation condition of peptides in reversed-phase liquid chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20040205

Title: Liquid chromatographic determination of pyronaridine in human plasma and oral dosage form.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 20031005

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