135304-07-3
[1]Patent:WO2010/90845,2010,A1.Locationinpatent:Page/Pagecolumn82
Title: N-acetyl-S-farnesyl-l-cysteine suppresses chemokine production by human dermal microvascular endothelial cells.
Journal: Experimental dermatology 20120901
Title: Evaluation of substrate and inhibitor binding to yeast and human isoprenylcysteine carboxyl methyltransferases (Icmts) using biotinylated benzophenone-containing photoaffinity probes.
Journal: Biochemical and biophysical research communications 20120622
Title: Amide-modified prenylcysteine based Icmt inhibitors: Structure-activity relationships, kinetic analysis and cellular characterization.
Journal: Bioorganic & medicinal chemistry 20120101
Title: N-Acetylfarnesylcysteine is a novel class of peroxisome proliferator-activated receptor γ ligand with partial and full agonist activity in vitro and in vivo.
Journal: The Journal of biological chemistry 20111202
Title: Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis.
Journal: Bioorganic & medicinal chemistry letters 20101101
Title: Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site.
Journal: The Journal of investigative dermatology 20080301
Title: Drugs affecting prelamin A processing: effects on heterochromatin organization.
Journal: Experimental cell research 20080201
Title: Genetic and pharmacologic analyses of the role of Icmt in Ras membrane association and function.
Journal: Methods in enzymology 20060101
Title: Purification, functional reconstitution, and characterization of the Saccharomyces cerevisiae isoprenylcysteine carboxylmethyltransferase Ste14p.
Journal: The Journal of biological chemistry 20050225
Title: Carboxyl methylation of Ras regulates membrane targeting and effector engagement.
Journal: The Journal of biological chemistry 20040220
Title: Studies on G-protein alpha.betagamma heterotrimer formation reveal a putative S-prenyl-binding site in the alpha subunit.
Journal: The Biochemical journal 20031201
Title: Prenylcysteine carboxymethyltransferase type III activity is decreased in retinoic acid-treated SH-SY5Y neuroblastoma cells.
Journal: The international journal of biochemistry & cell biology 20020501
Title: Role of isoprenylcysteine carboxyl methyltransferase in tumor necrosis factor-alpha stimulation of expression of vascular cell adhesion molecule-1 in endothelial cells.
Journal: Arteriosclerosis, thrombosis, and vascular biology 20020501
Title: Carboxyl-methylation of Rab3D in the rat pancreatic acinar tumor cell line AR42J.
Journal: Biochemical and biophysical research communications 20010720
Title: Farnesyl-L-cysteine analogs block SAM-induced Parkinson's disease-like symptoms in rats.
Journal: Pharmacology, biochemistry, and behavior 20000801
Title: Dislodgment and accelerated degradation of Ras.
Journal: Biochemistry 19980203
Title: Gordon JS, et al. Topical N-acetyl-S-farnesyl-L-cysteine inhibits mouse skin inflammation, and unlike dexamethasone, its effects are restricted to the application site.J Invest Dermatol. 2008 Mar;128(3):643-54. Epub 2007 Sep 20.
Title: Adhami K, et al. N-acetyl-S-farnesyl-l-cysteine suppresses chemokine production by human dermal microvascular endothelial cells.Exp Dermatol. 2012 Sep;21(9):700-5.
