118675-50-6,MFCD00877696
Catalog No.:AA0080WS

118675-50-6 | 4-Imidazolidineheptanoicacid, 3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxo-1-(phenylmethyl)-

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$125.00   $87.00
- +
5mg
≥98%
in stock  
$549.00   $384.00
- +
10mg
≥98%
in stock  
$972.00   $680.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA0080WS
Chemical Name:
4-Imidazolidineheptanoicacid, 3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxo-1-(phenylmethyl)-
CAS Number:
118675-50-6
Molecular Formula:
C25H37N3O5
Molecular Weight:
459.5784
MDL Number:
MFCD00877696
SMILES:
OC(=O)CCCCCCC1N(NCC(C2CCCCC2)O)C(=O)N(C1=O)Cc1ccccc1
Properties
Computed Properties
 
Complexity:
646  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
13  
Undefined Atom Stereocenter Count:
2  
XLogP3:
1.7  

Literature

Title: Complement C5a exhibits anxiolytic-like activity via the prostaglandin D2-DP1 receptor system coupled to adenosine A2A and GABAA receptors.

Journal: Prostaglandins & other lipid mediators 20120501

Title: PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis.

Journal: The Journal of allergy and clinical immunology 20120201

Title: Induction of apoptosis in non-small cell lung carcinoma A549 cells by PGD₂ metabolite, 15d-PGJ₂.

Journal: Cell biology international 20111101

Title: Complement C5a stimulates food intake via a prostaglandin D(2)- and neuropeptide Y-dependent mechanism in mice.

Journal: Prostaglandins & other lipid mediators 20091201

Title: GIF-0173 protects against cerebral infarction through DP1 receptor activation.

Journal: Experimental neurology 20091001

Title: Central prostaglandin D(2) exhibits anxiolytic-like activity via the DP(1) receptor in mice.

Journal: Prostaglandins & other lipid mediators 20090401

Title: Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.

Journal: Journal of leukocyte biology 20090101

Title: Involvement of chemical mediators in nasal allergic responses of HDC-KO mice.

Journal: European journal of pharmacology 20070719

Title: Effects of TS-022, a newly developed prostanoid DP1 receptor agonist, on experimental pruritus, cutaneous barrier disruptions and atopic dermatitis in mice.

Journal: European journal of pharmacology 20070205

Title: Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats.

Journal: European journal of pharmacology 20070112

Title: Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor.

Journal: The Journal of pharmacology and experimental therapeutics 20050301

Title: A functional study on prostanoid receptors involved in cultured human iridal melanocyte stimulation.

Journal: Experimental eye research 20010701

Title: Pharmacology and autoradiography of human DP prostanoid receptors using [(3)H]-BWA868C, a DP receptor-selective antagonist radioligand.

Journal: British journal of pharmacology 20001101

Title: Regulation of endothelial nitric oxide synthase by PGD(2) in the developing choroid.

Journal: American journal of physiology. Heart and circulatory physiology 20000101

Title: Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.

Journal: British journal of pharmacology 19980401

Title: Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.

Journal: British journal of pharmacology 19970901

Title: Molecular cloning and characterization of the human prostanoid DP receptor.

Journal: The Journal of biological chemistry 19950811

Title: The role of prostanoid TP- and DP-receptors in the bronchoconstrictor effect of inhaled PGD2 in anaesthetized guinea-pigs: effect of the DP-antagonist BW A868C.

Journal: British journal of pharmacology 19900801

Title: The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist.

Journal: British journal of pharmacology 19890201

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Tags:118675-50-6 Molecular Formula|118675-50-6 MDL|118675-50-6 SMILES|118675-50-6 4-Imidazolidineheptanoicacid, 3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxo-1-(phenylmethyl)-
Catalog No.: AA0080WS
118675-50-6,MFCD00877696
118675-50-6 | 4-Imidazolidineheptanoicacid, 3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxo-1-(phenylmethyl)-
Pack Size: 1mg
Purity: ≥98%
in stock
$125.00 $87.00
Pack Size: 5mg
Purity: ≥98%
in stock
$549.00 $384.00
Pack Size: 10mg
Purity: ≥98%
in stock
$972.00 $680.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA0080WS
Chemical Name: 4-Imidazolidineheptanoicacid, 3-[(2-cyclohexyl-2-hydroxyethyl)amino]-2,5-dioxo-1-(phenylmethyl)-
CAS Number: 118675-50-6
Molecular Formula: C25H37N3O5
Molecular Weight: 459.5784
MDL Number: MFCD00877696
SMILES: OC(=O)CCCCCCC1N(NCC(C2CCCCC2)O)C(=O)N(C1=O)Cc1ccccc1
Properties
Complexity: 646  
Covalently-Bonded Unit Count: 1  
Heavy Atom Count: 33  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 3  
Rotatable Bond Count: 13  
Undefined Atom Stereocenter Count: 2  
XLogP3: 1.7  
Literature fold

Title: Complement C5a exhibits anxiolytic-like activity via the prostaglandin D2-DP1 receptor system coupled to adenosine A2A and GABAA receptors.

Journal: Prostaglandins & other lipid mediators20120501

Title: PGD2 induces eotaxin-3 via PPARγ from sebocytes: a possible pathogenesis of eosinophilic pustular folliculitis.

Journal: The Journal of allergy and clinical immunology20120201

Title: Induction of apoptosis in non-small cell lung carcinoma A549 cells by PGD₂ metabolite, 15d-PGJ₂.

Journal: Cell biology international20111101

Title: Complement C5a stimulates food intake via a prostaglandin D(2)- and neuropeptide Y-dependent mechanism in mice.

Journal: Prostaglandins & other lipid mediators20091201

Title: GIF-0173 protects against cerebral infarction through DP1 receptor activation.

Journal: Experimental neurology20091001

Title: Central prostaglandin D(2) exhibits anxiolytic-like activity via the DP(1) receptor in mice.

Journal: Prostaglandins & other lipid mediators20090401

Title: Prostaglandin H2 induces the migration of human eosinophils through the chemoattractant receptor homologous molecule of Th2 cells, CRTH2.

Journal: Journal of leukocyte biology20090101

Title: Involvement of chemical mediators in nasal allergic responses of HDC-KO mice.

Journal: European journal of pharmacology20070719

Title: Effects of TS-022, a newly developed prostanoid DP1 receptor agonist, on experimental pruritus, cutaneous barrier disruptions and atopic dermatitis in mice.

Journal: European journal of pharmacology20070205

Title: Interactive effect of histamine and prostaglandin D2 on nasal allergic symptoms in rats.

Journal: European journal of pharmacology20070112

Title: Prostaglandin D2-induced eosinophilic airway inflammation is mediated by CRTH2 receptor.

Journal: The Journal of pharmacology and experimental therapeutics20050301

Title: A functional study on prostanoid receptors involved in cultured human iridal melanocyte stimulation.

Journal: Experimental eye research20010701

Title: Pharmacology and autoradiography of human DP prostanoid receptors using [(3)H]-BWA868C, a DP receptor-selective antagonist radioligand.

Journal: British journal of pharmacology20001101

Title: Regulation of endothelial nitric oxide synthase by PGD(2) in the developing choroid.

Journal: American journal of physiology. Heart and circulatory physiology20000101

Title: Characterization of the recombinant human prostanoid DP receptor and identification of L-644,698, a novel selective DP agonist.

Journal: British journal of pharmacology19980401

Title: Ligand binding specificities of the eight types and subtypes of the mouse prostanoid receptors expressed in Chinese hamster ovary cells.

Journal: British journal of pharmacology19970901

Title: Molecular cloning and characterization of the human prostanoid DP receptor.

Journal: The Journal of biological chemistry19950811

Title: The role of prostanoid TP- and DP-receptors in the bronchoconstrictor effect of inhaled PGD2 in anaesthetized guinea-pigs: effect of the DP-antagonist BW A868C.

Journal: British journal of pharmacology19900801

Title: The classification of prostaglandin DP-receptors in platelets and vasculature using BW A868C, a novel, selective and potent competitive antagonist.

Journal: British journal of pharmacology19890201

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