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Home Amines 1036260-43-1
1036260-43-1,MFCD09029034
Catalog No.:AA0085IB

1036260-43-1 | Cis-3-aminocyclobutanol

Pack Size
Purity
Availability
Price(USD)
Quantity
  
250mg
96%
in stock  
$311.00   $218.00
- +
1g
96%
in stock  
$760.00   $532.00
- +
5g
96%
in stock  
$2,672.00   $1,870.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA0085IB
Chemical Name:
Cis-3-aminocyclobutanol
CAS Number:
1036260-43-1
Molecular Formula:
C4H9NO
Molecular Weight:
87.1204
MDL Number:
MFCD09029034
SMILES:
N[C@@H]1C[C@@H](C1)O
Properties
Computed Properties
 
Complexity:
49.5  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
6  
Hydrogen Bond Acceptor Count:
2  
Hydrogen Bond Donor Count:
2  
XLogP3:
-0.8  

Downstream Synthesis Route

[1]Zhao,Yujun;Yu,Shanghai;Sun,Wei;Liu,Liu;Lu,Jianfeng;McEachern,Donna;Shargary,Sanjeev;Bernard,Denzil;Li,Xiaoqin;Zhao,Ting;Zou,Peng;Sun,Duxin;Wang,Shaomeng[JournalofMedicinalChemistry,2013,vol.56,#13,p.5553-5561]

1036260-43-1   
4-chloro-7-fluoro-6-6-(methoxymethyl)-3-pyridinyl-3-quinolinecarboxamide 
 
7-fluoro-4-((cis-3-hydroxycyclobutyl)amino)-6-(6-(methoxymethyl)pyridin-3-yl)quinoline-3-carboxamide 

[1]Pike,KurtG.;Barlaam,Bernard;Cadogan,Elaine;Campbell,Andrew;Chen,Yingxue;Colclough,Nicola;Davies,NicholaL.;De-Almeida,Camila;Degorce,SebastienL.;Didelot,Myriam;Dishington,Allan;Ducray,Richard;Durant,StephenT.;Hassall,LorraineA.;Holmes,Jane;Hughes,GarethD.;Macfaul,PhilipA.;Mulholland,KeithR.;McGuire,ThomasM.;Ouvry,Gilles;Pass,Martin;Robb,Graeme;Stratton,Natalie;Wang,Zhenhua;Wilson,Joanne;Zhai,Baochang;Zhao,Kang;Al-Huniti,Nidal[JournalofMedicinalChemistry,2018,vol.61,#9,p.3823-3841]

1036260-43-1    206257-39-8   
ethyl6-bromo-4-(cis-3-hydroxycyclobutyl)aminoquinoline-3-carboxylate 

[1]Pike,KurtG.;Barlaam,Bernard;Cadogan,Elaine;Campbell,Andrew;Chen,Yingxue;Colclough,Nicola;Davies,NicholaL.;De-Almeida,Camila;Degorce,SebastienL.;Didelot,Myriam;Dishington,Allan;Ducray,Richard;Durant,StephenT.;Hassall,LorraineA.;Holmes,Jane;Hughes,GarethD.;Macfaul,PhilipA.;Mulholland,KeithR.;McGuire,ThomasM.;Ouvry,Gilles;Pass,Martin;Robb,Graeme;Stratton,Natalie;Wang,Zhenhua;Wilson,Joanne;Zhai,Baochang;Zhao,Kang;Al-Huniti,Nidal[JournalofMedicinalChemistry,2018,vol.61,#9,p.3823-3841]

1036260-43-1    474659-26-2   
N-((1s,3s)-3-hydroxycyclobutyl)-7-methoxyquinoline-3-carboxamide 

[1]Deaton,DavidN.;Do,Young;Holt,Jason;Jeune,MichaelR.;Kramer,H.Fritz;Larkin,AndrewL.;Orband-Miller,LisaA.;Peckham,GregoryE.;Poole,Chuck;Price,DanielJ.;Schaller,LeeT.;Shen,Ying;Shewchuk,LisaM.;Stewart,EugeneL.;Stuart,J.Darren;Thomson,StephenA.;Ward,Paris;Wilson,JosephW.;Xu,Tianshun;Guss,JeffreyH.;Musetti,Caterina;Rendina,AlanR.;Affleck,Karen;Anders,David;Hancock,AshleyP.;Hobbs,Heather;Hodgson,SimonT.;Hutchinson,Jonathan;Leveridge,MelanieV.;Nicholls,Harry;Smith,IanE.D.;Somers,DonO.;Sneddon,HelenF.;Uddin,Sorif;Cleasby,Anne;Mortenson,PaulN.;Richardson,Caroline;Saxty,Gordon[BioorganicandMedicinalChemistry,2019,vol.27,#8,p.1456-1478]

1036260-43-1   
2-(5-amino-2-(furan-2-yl)-7H-pyrazolo4,3-e1,2,4triazolo1,5-cpyrimidin-7-yl)-2-phenylpropanoicacid 
 
2-(5-amino-2-(furan-2-yl)-7H-pyrazolo4,3-e1,2,4triazolo1,5-cpyrimidin-7-yl)-N-((1s,3s)-3-hydroxycyclobutyl)-2-phenylpropanamide 

[1]CurrentPatentAssignee:BEIGENELTD.-WO2019/196803,2019,A1Locationinpatent:Paragraph0534

Literature

Title: Stereoselective synthesis of cis-1,3-disubstituted cyclobutyl kinase inhibitors.

Journal: Organic letters 20040527

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Tags:1036260-43-1 Molecular Formula|1036260-43-1 MDL|1036260-43-1 SMILES|1036260-43-1 Cis-3-aminocyclobutanol