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Title: Ruthenium polypyridyl complexes and their modes of interaction with DNA: is there a correlation between these interactions and the antitumor activity of the compounds?
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Title: Organometallic osmium(II) arene anticancer complexes containing picolinate derivatives.
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Title: Guanine radical reaction processes: a computational description of proton transfer in X-irradiated 9-ethylguanine single crystals.
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Title: The contrasting chemistry and cancer cell cytotoxicity of bipyridine and bipyridinediol ruthenium(II) arene complexes.
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Title: Ruthenium(III) chloride complex with a tridentate bis(arylimino)pyridine ligand: synthesis, spectra, X-ray structure, 9-ethylguanine binding pattern, and in vitro cytotoxicity.
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Title: Incorporating molecular tools into early-stage clinical trials.
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Title: In vitro anticancer activity and biologically relevant metabolization of organometallic ruthenium complexes with carbohydrate-based ligands.
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Title: An enolisable barbiturate with adjustable hydrogen-bonding structure for UV/Vis detection of nucleic acid bases and related compounds.
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Title: Chlorido-, aqua-, 9-ethylguanine- and 9-ethyladenine-adducts of cytotoxic ruthenium arene complexes containing O,O-chelating ligands.
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Title: Bifunctional amine-tethered ruthenium(II) arene complexes form monofunctional adducts on DNA.
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Title: The mid-IR spectra of 9-ethyl guanine, guanosine, and 2-deoxyguanosine.
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Title: Interaction between the DNA model base 9-ethylguanine and a group of ruthenium polypyridyl complexes: kinetics and conformational temperature dependence.
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Title: Structure of radicals from X-irradiated guanine derivatives. 2. An experimental and computational study of 9-ethylguanine single crystals.
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Title: Determination of aciclovir and ganciclovir in human plasma by liquid chromatography-spectrofluorimetric detection and stability studies in blood samples.
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Title: Chloro half-sandwich osmium(II) complexes: influence of chelated N,N-ligands on hydrolysis, guanine binding, and cytotoxicity.
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Title: Interguanine hydrogen-bonding patterns in adducts with water and Zn-purine complexes (purine is 9-methyladenine and 9-methylguanine). Unexpected preference of Zn(II) for adenine-N7 over guanine-N7.
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Title: Tuning the hydrolytic aqueous chemistry of osmium arene complexes with N,O-chelating ligands to achieve cancer cell cytotoxicity.
Journal: Journal of the American Chemical Society 20070321
Title: Osmium(II) and ruthenium(II) arene maltolato complexes: rapid hydrolysis and nucleobase binding.
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Title: Dirhodium(II,II) complexes: molecular characteristics that affect in vitro activity.
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Title: Multiple metal binding to 6-oxopurine nucleobases as a source of deprotonation. The role of metal ions at N7 and N3.
Journal: Dalton transactions (Cambridge, England : 2003) 20060828
Title: Head-to-head cross-linked adduct between the antitumor unit bis(mu-N,N'-di-p-tolylformamidinato)dirhodium(II,II) and the DNA fragment d(GpG).
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Title: The neglected Pt-N(sulfonamido) bond in Pt chemistry. New fluorophore-containing Pt(II) complexes useful for assessing Pt(II) interactions with biomolecules.
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Title: Covalent and noncovalent interactions for [metal(dien)nucleobase](2+) complexes with L-tryptophan derivatives: formation of palladium-tryptophan species by nucleobase substitution under biologically relevant conditions.
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Title: Tuning the reactivity of osmium(II) and ruthenium(II) arene complexes under physiological conditions.
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Title: cis-[Rh2(mu-O2CCH3)2(CH3CN)6]2+ as a photoactivated cisplatin analog.
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Title: G-G base-pairing in nucleobase adducts of the anticancer drug cis-[PtCl2(NH3)(2-picoline)] and its trans isomer.
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Title: Cationic tetrakis(nucleobase)complexes of PtII as metalloligands and potential building blocks for molecular architectures.
Journal: Dalton transactions (Cambridge, England : 2003) 20050505
Title: Model platinum nucleobase and nucleoside complexes and antitumor activity: X-ray crystal structure of [PtIV(trans-1R,2R-diaminocyclohexane)trans-(acetate)2(9-ethylguanine)Cl]NO3.H2O.
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Title: Photoinitiated DNA Binding by cis-[Ru(bpy)2(NH3)2]2+.
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Title: A highly flexible dinuclear ruthenium(II)-platinum(II) complex: crystal structure and binding to 9-ethylguanine.
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Title: Coordination of 9-ethylguanine to the mixed-ligand compound alpha-[Ru(azpy)(bpy)Cl2] (azpy = 2-phenylazopyridine and bpy = 2,2'-bipyridine). An unprecedented ligand positional shift, correlated to the cytotoxicity of this type of [RuL2Cl2] (with L = azpy or bpy) complex.
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Title: Reactions of 9-substituted guanines with bromomalondialdehyde in aqueous solution predominantly yield glyoxal-derived adducts.
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Title: Unprecedented head-to-head conformers of d(GpG) bound to the antitumor active compound tetrakis (mu-carboxylato)dirhodium(II,II).
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Title: Novel binding interactions of the DNA fragment d(pGpG) cross-linked by the antitumor active compound tetrakis(mu-carboxylato)dirhodium(II,II).
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Title: Intrinsic acid-base properties of purine derivatives in aqueous solution and comparison of the acidifying effects of platinum(II) coordinated to N1 or N7: acidifying effects are reciprocal and the proton 'outruns' divalent metal ions.
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Title: Simultaneous N7,O6-binding of guanine to two zinc centers and its possible biological significance.
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Title: A novel isomerization on interaction of antitumor-active azole-bridged dinuclear platinum(II) complexes with 9-ethylguanine. Platinum(II) atom migration from N2 to N3 on 1,2,3-triazole.
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Title: Organometallic ruthenium(II) diamine anticancer complexes: arene-nucleobase stacking and stereospecific hydrogen-bonding in guanine adducts.
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Title: Metal-modified nucleobase sextet: joining four linear metal fragments (trans-a2PtII) and six model nucleobases to an exceedingly stable entity.
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Title: Alkylpurines as immunopotentiating agents. Synthesis and antiviral activity of certain alkylguanines.
Journal: Journal of medicinal chemistry 19931029
