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86329-79-5,MFCD00897059
Catalog No.:AA008EP3

86329-79-5 | Cefodizime Disodium

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Purity
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25mg
98%(HPLC)
in stock  
$47.00   $33.00
- +
100mg
98%(HPLC)
in stock  
$107.00   $75.00
- +
250mg
98%
in stock  
$149.00   $104.00
- +
1g
98%(HPLC)
in stock  
$320.00   $224.00
- +
5g
98%
in stock  
$893.00   $625.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008EP3
Chemical Name:
Cefodizime Disodium
CAS Number:
86329-79-5
Molecular Formula:
C20H18N6Na2O7S4
Molecular Weight:
628.6325
MDL Number:
MFCD00897059
SMILES:
CO/N=C(/c1csc(n1)N)\C(=O)N[C@@H]1C(=O)N2[C@@H]1SCC(=C2C(=O)[O-])CSc1nc(c(s1)CC(=O)[O-])C.[Na+].[Na+]
Properties
Computed Properties
 
Complexity:
1020  
Covalently-Bonded Unit Count:
3  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
15  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  

Literature

Title: BioDMET: a physiologically based pharmacokinetic simulation tool for assessing proposed solutions to complex biological problems.

Journal: Journal of pharmacokinetics and pharmacodynamics 20120201

Title: Effects of cefodizime on chemokines of liver tissues in mice with immunological hepatic injury.

Journal: Chinese medical journal 20110301

Title: Microemulsion and mixed micelle for oral administration as new drug formulations for highly hydrophilic drugs.

Journal: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V 20100201

Title: Implications of current recommendations for third-generation cephalosporin use in the WHO Western Pacific Region following the emergence of multiresistant gonococci.

Journal: Sexually transmitted infections 20090801

Title: Preparation, physicochemical characterization and biological evaluation of cefodizime metal ion complexes.

Journal: The Journal of pharmacy and pharmacology 20090601

Title: Inhibitory effects of Cefazolin and Cefodizime on the activity of mushroom tyrosinase.

Journal: Journal of enzyme inhibition and medicinal chemistry 20090201

Title: Population pharmacokinetics with a very small sample size.

Journal: Drug metabolism and drug interactions 20090101

Title: Multiple doses of cefodizime are necessary for the treatment of Neisseria gonorrhoeae pharyngeal infection.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060601

Title: The effects of some antibiotics on polymorphonuclear leukocyte functions of elderly patients in vitro before and after zinc supplementation.

Journal: International immunopharmacology 20060501

Title: Single-dose pharmacokinetics of cefodizime in critically ill elderly patients.

Journal: International journal of antimicrobial agents 20060401

Title: Single dose of cefodizime completely eradicated multidrug-resistant strain of Neisseria gonorrhoeae in urethritis and uterine cervicitis.

Journal: Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20060401

Title: Selective immediate hypersensitivity to cefodizime.

Journal: Allergy 20051201

Title: [Pharyngeal gonococcal infections].

Journal: Nihon Jibiinkoka Gakkai kaiho 20040801

Title: Influence of enhancers on the absorption and on the pharmacokinetics of cefodizime using in-vitro and in-vivo models.

Journal: The Journal of pharmacy and pharmacology 20040401

Title: Immunomodulating effects of cefodizime on Klebsiella pneumoniae-stimulated neutrophils.

Journal: Immunobiology 20040101

Title: [Gonococcal infection].

Journal: Nihon rinsho. Japanese journal of clinical medicine 20030201

Title: Outbreak of acute renal failure due to cefodizime-vancomycin association in a heart surgery unit.

Journal: Intensive care medicine 20011101

Title: In vitro effect of amikacin, imipenem, cefodizime, IFNalpha-2a alone and combinations of antibiotics with IFNalpha-2a on polymorphonuclear leukocyte function in chronic hepatitis patients.

Journal: Chemotherapy 20010101

Title: Induction of tumor necrosis factor-alpha by cefodizime in U-937 cells.

Journal: Revista de investigacion clinica; organo del Hospital de Enfermedades de la Nutricion 20010101

Title: Stability of cefodizime disodium in solid state.

Journal: Acta poloniae pharmaceutica 20010101

Title: [Acute toxicity study of cefodizime sodium].

Journal: The Journal of toxicological sciences 19880601

Title: [Six-month chronic intravenous toxicity study of cefodizime sodium in dogs].

Journal: The Journal of toxicological sciences 19880601

Title: [Nephrotoxicity of cefodizime sodium in rats--single and 14-day repeated intravenous administration].

Journal: The Journal of toxicological sciences 19880601

Title: [Six-month chronic subcutaneous toxicity study of cefodizime sodium in rats].

Journal: The Journal of toxicological sciences 19880601

Title: Barradell LB, et al. Cefodizime. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use. Drugs. 1992 Nov;44(5):800-34.

Title: Hu T, et al. Probing the interaction of cefodizime with human serum albumin using multi-spectroscopic and molecular docking techniques. J Pharm Biomed Anal. 2015 Mar 25;107:325-32.

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