Home Other Building Blocks 79236-56-9
79236-56-9,MFCD08669600
Catalog No.:AA008MJC

79236-56-9 | N-Methyl Protoporphyrin IX

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1mg
≥95% (a mixture of isomers)
in stock  
$112.00   $78.00
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5mg
≥95% (a mixture of isomers)
in stock  
$276.00   $193.00
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  • Technical Information
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008MJC
Chemical Name:
N-Methyl Protoporphyrin IX
CAS Number:
79236-56-9
Molecular Formula:
C35H36N4O4
Molecular Weight:
576.6847
MDL Number:
MFCD08669600
SMILES:
C=Cc1c2C=C3N=C(C(=C3C)CCC(=O)O)C=C3N=C(C=c4n(c(=Cc(c1C)[nH]2)c(C=C)c4C)C)C(=C3CCC(=O)O)C
Properties
Computed Properties
 
Complexity:
1040  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
43  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
8  
XLogP3:
4.6  

Literature

Title: Chronic Treatment with Isoniazid Causes Protoporphyrin IX Accumulation in Mouse Liver.

Journal: Chemical research in toxicology 20160815

Title: Heme and heme biosynthesis intermediates induce heme oxygenase-1 and cytochrome P450 2A5, enzymes with putative sequential roles in heme and bilirubin metabolism: different requirement for transcription factor nuclear factor erythroid- derived 2-like 2.

Journal: Toxicological sciences : an official journal of the Society of Toxicology 20121101

Title: Heme reversibly damps PERIOD2 rhythms in mouse suprachiasmatic nucleus explants.

Journal: Neuroscience 20091201

Title: Inhibition of heme synthesis alters Amyloid Precursor Protein processing.

Journal: Journal of neural transmission (Vienna, Austria : 1996) 20090101

Title: Impaired dexamethasone-mediated induction of tryptophan 2,3-dioxygenase in heme-deficient rat hepatocytes: translational control by a hepatic eIF2alpha kinase, the heme-regulated inhibitor.

Journal: The Journal of pharmacology and experimental therapeutics 20071201

Title: Modulation of inhibition of ferrochelatase by N-methylprotoporphyrin.

Journal: The Biochemical journal 20061001

Title: Recombinant cytochromes c biogenesis systems I and II and analysis of haem delivery pathways in Escherichia coli.

Journal: Molecular microbiology 20060501

Title: Heme-reversible impairment of CYP2B1/2 induction in heme-depleted rat hepatocytes in primary culture: translational control by a hepatic alpha-subunit of the eukaryotic initiation factor kinase?

Journal: The Journal of pharmacology and experimental therapeutics 20050701

Title: Erythropoietin induction in Hep3B cells is not affected by inhibition of heme biosynthesis.

Journal: Biochimica et biophysica acta 20000227

Title: Three-dimensional structure-activity analysis of a series of porphyrin derivatives with anti-HIV-1 activity targeted to the V3 loop of the gp120 envelope glycoprotein of the human immunodeficiency virus type 1.

Journal: Journal of medicinal chemistry 19940415

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