Home Amines 115416-38-1
115416-38-1,MFCD00216002
Catalog No.:AA008SMW

115416-38-1 | 5-(Biotinamido)pentylamine

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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
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  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
Technical Information
Catalog Number:
AA008SMW
Chemical Name:
5-(Biotinamido)pentylamine
CAS Number:
115416-38-1
Molecular Formula:
C15H28N4O2S
Molecular Weight:
328.4734
MDL Number:
MFCD00216002
SMILES:
NCCCCCNC(=O)CCCC[C@@H]1SC[C@H]2[C@@H]1NC(=O)N2
Properties
Computed Properties
 
Complexity:
381  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
3  
Heavy Atom Count:
22  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
4  
Rotatable Bond Count:
10  
XLogP3:
0.2  

Downstream Synthesis Route
1221343-14-1    115416-38-1   
C23H33BN4O5S 

[1]Guy,ColletteS.;Murray,Kathryn;Gibson,MatthewI.;Fullam,Elizabeth[OrganicandBiomolecularChemistry,2019,vol.17,#43,p.9524-9528]

756525-91-4    115416-38-1   
C31H57N5O9S 

[1]Esposito,Emiliano;Vlodavsky,Israel;Barash,Uri;Roscilli,Giuseppe;Milazzo,FerdinandoM.;Giannini,Giuseppe;Naggi,Annamaria[EuropeanJournalofMedicinalChemistry,2020,vol.186]

Literature

Title: Beta-actin is a target for transglutaminase activity at synaptic endings in chicken telencephalic cell cultures.

Journal: Journal of molecular neuroscience : MN 20120201

Title: Simultaneous activity assay of two transglutaminase isozymes, blood coagulation factor XIII and transglutaminase 2, by use of fibrinogen arrays.

Journal: Analytical chemistry 20111115

Title: N-formylkynurenine as a marker of high light stress in photosynthesis.

Journal: The Journal of biological chemistry 20110624

Title: Rapid determination of blood coagulation factor XIII activity using protein arrays for serodiagnosis of human plasma.

Journal: Analytical chemistry 20110315

Title: Dual induction of caspase 3- and transglutaminase-dependent apoptosis by acyclic retinoid in hepatocellular carcinoma cells.

Journal: Molecular cancer 20110101

Title: Cytosolic guanine nucledotide binding deficient form of transglutaminase 2 (R580a) potentiates cell death in oxygen glucose deprivation.

Journal: PloS one 20110101

Title: Astrocyte-derived tissue transglutaminase interacts with fibronectin: a role in astrocyte adhesion and migration?

Journal: PloS one 20110101

Title: Model thrombi formed under flow reveal the role of factor XIII-mediated cross-linking in resistance to fibrinolysis.

Journal: Journal of thrombosis and haemostasis : JTH 20100901

Title: Complete sequencing of the recombinant granulocyte-colony stimulating factor (filgrastim) and detection of biotinylation by mass spectrometry.

Journal: Amino acids 20100401

Title: Neuroprotective effects of calmodulin peptide 76-121aa: disruption of calmodulin binding to mutant huntingtin.

Journal: Brain pathology (Zurich, Switzerland) 20100101

Title: Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer.

Journal: PloS one 20100101

Title: Identification and ultrastructural imaging of photodynamic therapy-induced microfilaments by atomic force microscopy.

Journal: Ultramicroscopy 20091101

Title: Identification of the major TG4 cross-linking sites in the androgen-dependent SVS I exclusively expressed in mouse seminal vesicle.

Journal: Journal of cellular biochemistry 20090801

Title: A nonradioactive dot blot assay for transglutaminase activity.

Journal: Analytical biochemistry 20090701

Title: Intracellular localization and conformational state of transglutaminase 2: implications for cell death.

Journal: PloS one 20090101

Title: Reactivity of fish and microbial transglutaminases on glutaminyl sites of peptides derived from threadfin bream myosin.

Journal: Journal of agricultural and food chemistry 20080827

Title: Identification of new amine acceptor protein substrate candidates of transglutaminase in rat liver extract: use of 5-(biotinamido) pentylamine as a probe.

Journal: Bioscience, biotechnology, and biochemistry 20080401

Title: Transglutaminase activity in the hematopoietic tissue of a crustacean, Pacifastacus leniusculus, importance in hemocyte homeostasis.

Journal: BMC immunology 20080101

Title: Why alpha-antiplasmin must be converted to a derivative form for optimal function.

Journal: Journal of thrombosis and haemostasis : JTH 20071001

Title: State of differentiation defines buccal epithelial cell affinity for cross-linking to Candida albicans Hwp1.

Journal: Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 20070901

Title: Transglutaminase 1 stabilizes beta-actin in endothelial cells correlating with a stabilization of intercellular junctions.

Journal: Journal of vascular research 20070101

Title: Arterial vimentin is a transglutaminase substrate: a link between vasomotor activity and remodeling?

Journal: Journal of vascular research 20070101

Title: Construction of miniantibodies for the in vivo study of human autoimmune diseases in animal models.

Journal: BMC biotechnology 20070101

Title: The isothiocyanate class of bioactive nutrients covalently inhibit the MEKK1 protein kinase.

Journal: BMC cancer 20070101

Title: Development and evaluation of a modified colorimetric solid-phase microassay for measuring the activity of cellular and plasma (Factor XIII) transglutaminases.

Journal: Biotechnology and applied biochemistry 20060301

Title: Colorimetric transglutaminase assays combined with immunological signal amplification.

Journal: Analytical biochemistry 20060115

Title: Small artery remodeling depends on tissue-type transglutaminase.

Journal: Circulation research 20050107

Title: Immobilization of streptavidin-horseradish peroxidase onto a biotinylated poly(acrylic acid) backbone that had been radiation-grafted to a PTFE film.

Journal: Journal of biomaterials science. Polymer edition 20050101

Title: In vitro modification of betaine-homocysteine S-methyltransferase by tissue-type transglutaminase.

Journal: The international journal of biochemistry & cell biology 20041001

Title: Expression of transglutaminase substrate activity on Candida albicans germ tubes through a coiled, disulfide-bonded N-terminal domain of Hwp1 requires C-terminal glycosylphosphatidylinositol modification.

Journal: The Journal of biological chemistry 20040924

Title: Instability of the biotin-protein bond in human plasma.

Journal: Analytical biochemistry 20040415

Title: Proteomics identification of acyl-acceptor and acyl-donor substrates for transglutaminase in a human intestinal epithelial cell line. Implications for celiac disease.

Journal: The Journal of biological chemistry 20030822

Title: Expression and enzymatic activity of small intestinal tissue transglutaminase in celiac disease.

Journal: The American journal of gastroenterology 20030801

Title: Analysis of transglutaminase protein substrates by functional proteomics.

Journal: Protein science : a publication of the Protein Society 20030601

Title: Evaluation of a sensitive colorimetric FXIII incorporation assay. Effects of FXIII Val34Leu, plasma fibrinogen concentration and congenital FXIII deficiency.

Journal: Thrombosis research 20010401

Title: Three different human tau isoforms and rat neurofilament light, middle and heavy chain proteins are cellular substrates for transglutaminase.

Journal: Neuroscience letters 20010126

Title: An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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Tags:115416-38-1 Molecular Formula|115416-38-1 MDL|115416-38-1 SMILES|115416-38-1 5-(Biotinamido)pentylamine