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1207360-89-1,MFCD22417087
Catalog No.:AA008TDK

1207360-89-1 | Gdc-0349

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$89.00   $62.00
- +
5mg
≥99%
in stock  
$313.00   $219.00
- +
10mg
≥99%
in stock  
$477.00   $334.00
- +
25mg
≥99%
in stock  
$1,002.00   $702.00
- +
50mg
≥99%
in stock  
$1,900.00   $1,330.00
- +
100mg
≥99%
in stock  
$3,375.00   $2,363.00
- +
  • Technical Information
  • Properties
  • Downstream Synthesis Route
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008TDK
Chemical Name:
Gdc-0349
CAS Number:
1207360-89-1
Molecular Formula:
C24H32N6O3
Molecular Weight:
452.5493
MDL Number:
MFCD22417087
SMILES:
CCNC(=O)Nc1ccc(cc1)c1nc2CN(CCc2c(n1)N1CCOC[C@@H]1C)C1COC1
Properties
Computed Properties
 
Complexity:
656  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
33  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
5  
XLogP3:
1.4  

Downstream Synthesis Route

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2010/14939,2010,A1Locationinpatent:Page/Pagecolumn199

[2]Pei,Zhonghua;Blackwood,Elizabeth;Liu,Lichuan;Malek,Shiva;Belvin,Marcia;Koehler,MichaelF.T.;Ortwine,DanielF.;Chen,Huifen;Cohen,Frederick;Kenny,JaneR.;Bergeron,Philippe;Lau,Kevin;Ly,Cuong;Zhao,Xianrui;Estrada,AnthonyA.;Truong,Tom;Epler,JenniferA.;Nonomiya,Jim;Trinh,Lan;Sideris,Steve;Lesnick,John;Bao,Linda;Vijapurkar,Ulka;Mukadam,Sophie;Tay,Suzanne;Deshmukh,Gauri;Chen,Yung-Hsiang;Ding,Xiao;Friedman,LoriS.;Lyssikatos,JosephP.[ACSMedicinalChemistryLetters,2013,vol.4,#1,p.103-107]

Literature

Title: Pei Z, et al. Discovery and Biological Profiling of Potent and Selective mTOR Inhibitor GDC-0349. ACS Med Chem Lett. 2012 Nov 29;4(1):103-7.

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SDS
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Tags:1207360-89-1 Molecular Formula|1207360-89-1 MDL|1207360-89-1 SMILES|1207360-89-1 Gdc-0349
Catalog No.: AA008TDK
1207360-89-1,MFCD22417087
1207360-89-1 | Gdc-0349
Pack Size： 1mg
Purity： ≥98%
in stock
$89.00 $62.00
Pack Size： 5mg
Purity： ≥99%
in stock
$313.00 $219.00
Pack Size： 10mg
Purity： ≥99%
in stock
$477.00 $334.00
Pack Size： 25mg
Purity： ≥99%
in stock
$1,002.00 $702.00
Pack Size： 50mg
Purity： ≥99%
in stock
$1,900.00 $1,330.00
Pack Size： 100mg
Purity： ≥99%
in stock
$3,375.00 $2,363.00
Quantity
- +
Add to Card
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bulk Quotation Request
Technical Information
Catalog Number: AA008TDK
Chemical Name: Gdc-0349
CAS Number: 1207360-89-1
Molecular Formula: C24H32N6O3
Molecular Weight: 452.5493
MDL Number: MFCD22417087
SMILES: CCNC(=O)Nc1ccc(cc1)c1nc2CN(CCc2c(n1)N1CCOC[C@@H]1C)C1COC1
Properties
Complexity: 656  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 33  
Hydrogen Bond Acceptor Count: 7  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 5  
XLogP3: 1.4  
Downstream Synthesis Route
6704-31-0    1207358-58-4    1207360-89-1 

[1]CurrentPatentAssignee:ROCHEHOLDINGAG-WO2010/14939,2010,A1Locationinpatent:Page/Pagecolumn199

[2]Pei,Zhonghua;Blackwood,Elizabeth;Liu,Lichuan;Malek,Shiva;Belvin,Marcia;Koehler,MichaelF.T.;Ortwine,DanielF.;Chen,Huifen;Cohen,Frederick;Kenny,JaneR.;Bergeron,Philippe;Lau,Kevin;Ly,Cuong;Zhao,Xianrui;Estrada,AnthonyA.;Truong,Tom;Epler,JenniferA.;Nonomiya,Jim;Trinh,Lan;Sideris,Steve;Lesnick,John;Bao,Linda;Vijapurkar,Ulka;Mukadam,Sophie;Tay,Suzanne;Deshmukh,Gauri;Chen,Yung-Hsiang;Ding,Xiao;Friedman,LoriS.;Lyssikatos,JosephP.[ACSMedicinalChemistryLetters,2013,vol.4,#1,p.103-107]

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