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1047634-65-0,MFCD28144686
Catalog No.:AA008TDZ

1047634-65-0 | GSK2141795

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98+%
in stock  
$34.00   $24.00
- +
5mg
98+%
in stock  
$83.00   $58.00
- +
10mg
98+%
in stock  
$123.00   $86.00
- +
50mg
98+%
in stock  
$316.00   $221.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008TDZ
Chemical Name:
GSK2141795
CAS Number:
1047634-65-0
Molecular Formula:
C18H16Cl2F2N4O2
Molecular Weight:
429.2480
MDL Number:
MFCD28144686
SMILES:
NCC(NC(=O)c1oc(c(c1)c1c(Cl)cnn1C)Cl)Cc1ccc(c(c1)F)F
Properties
Computed Properties
 
Complexity:
550  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
28  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
6  
XLogP3:
3.4  

Literature

Title: Discovery of novel AKT inhibitors with enhanced anti-tumor effects in combination with the MEK inhibitor.

Journal: PloS one 20140101

Title: Pachl F, et al. Characterization of a chemical affinity probe targeting Akt kinases. J Proteome Res. 2013 Aug 2;12(8):3792-800.

Title: Jacobsen K, et al. Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer. Nat Commun. 2017 Sep 4;8(1):410.

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SDS
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Tags:1047634-65-0 Molecular Formula|1047634-65-0 MDL|1047634-65-0 SMILES|1047634-65-0 GSK2141795
Catalog No.: AA008TDZ
1047634-65-0,MFCD28144686
1047634-65-0 | GSK2141795
Pack Size： 1mg
Purity： 98+%
in stock
$34.00 $24.00
Pack Size： 5mg
Purity： 98+%
in stock
$83.00 $58.00
Pack Size： 10mg
Purity： 98+%
in stock
$123.00 $86.00
Pack Size： 50mg
Purity： 98+%
in stock
$316.00 $221.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA008TDZ
Chemical Name: GSK2141795
CAS Number: 1047634-65-0
Molecular Formula: C18H16Cl2F2N4O2
Molecular Weight: 429.2480
MDL Number: MFCD28144686
SMILES: NCC(NC(=O)c1oc(c(c1)c1c(Cl)cnn1C)Cl)Cc1ccc(c(c1)F)F
Properties
Complexity: 550  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 1  
Heavy Atom Count: 28  
Hydrogen Bond Acceptor Count: 6  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 6  
XLogP3: 3.4  
Literature fold

Title: Discovery of novel AKT inhibitors with enhanced anti-tumor effects in combination with the MEK inhibitor.

Journal: PloS one20140101

Title: Pachl F, et al. Characterization of a chemical affinity probe targeting Akt kinases. J Proteome Res. 2013 Aug 2;12(8):3792-800.

Title: Jacobsen K, et al. Convergent Akt activation drives acquired EGFR inhibitor resistance in lung cancer. Nat Commun. 2017 Sep 4;8(1):410.

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