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Title: Synthesis and structure-activity relationships of a novel and selective bone morphogenetic protein receptor (BMP) inhibitor derived from the pyrazolo[1.5-a]pyrimidine scaffold of dorsomorphin: the discovery of ML347 as an ALK2 versus ALK3 selective MLPCN probe.
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Title: ΔNp63α-mediated activation of bone morphogenetic protein signaling governs stem cell activity and plasticity in normal and malignant mammary epithelial cells.
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Title: Inhibition of mTORC1 kinase activates Smads 1 and 5 but not Smad8 in human prostate cancer cells, mediating cytostatic response to rapamycin.
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Title: Inhibition of bone morphogenetic protein signaling reduces vascular calcification and atherosclerosis.
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Title: Pharmacological suppression of hepcidin increases macrophage cholesterol efflux and reduces foam cell formation and atherosclerosis.
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Title: The specificities of small molecule inhibitors of the TGFß and BMP pathways.
Journal: Cellular signalling 20111101
Title: Dorsomorphin stimulates neurite outgrowth in PC12 cells via activation of a protein kinase A-dependent MEK-ERK1/2 signaling pathway.
Journal: Genes to cells : devoted to molecular & cellular mechanisms 20111101
Title: Application of small organic molecules reveals cooperative TGFβ and BMP regulation of mesothelial cell behaviors.
Journal: ACS chemical biology 20110916
Title: Dorsomorphin and LDN-193189 inhibit BMP-mediated Smad, p38 and Akt signalling in C2C12 cells.
Journal: The international journal of biochemistry & cell biology 20101101
Title: [Cytokines in bone diseases. BMP signaling and fibrodysplasia ossificans progressiva].
Journal: Clinical calcium 20101001
Title: Intersegmental vessel formation in zebrafish: requirement for VEGF but not BMP signalling revealed by selective and non-selective BMP antagonists.
Journal: British journal of pharmacology 20100901
Title: Structure-activity relationship study of bone morphogenetic protein (BMP) signaling inhibitors.
Journal: Bioorganic & medicinal chemistry letters 20080801
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