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1206524-86-8,MFCD25976701
Catalog No.:AA008TFE

1206524-86-8 | MK-5172 Potassium

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
99%
1 week  
$222.00   $155.00
- +
10mg
99%
1 week  
$317.00   $222.00
- +
50mg
99%
1 week  
$908.00   $635.00
- +
100mg
99%
1 week  
$1,289.00   $902.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008TFE
Chemical Name:
MK-5172 Potassium
CAS Number:
1206524-86-8
Molecular Formula:
C38H49KN6O9S
Molecular Weight:
804.9938
MDL Number:
MFCD25976701
SMILES:
C=CC1CC1(NC(=O)C1CC2CN1C(=O)C(NC(=O)OC1CC1CCCCCc1c(O2)nc2cc(OC)ccc2n1)C(C)(C)C)C(=O)[N-]S(=O)(=O)C1CC1.[K+]
Properties
Computed Properties
 
Complexity:
1590  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
7  
Heavy Atom Count:
55  
Hydrogen Bond Acceptor Count:
12  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  

Literature

Title: Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor.

Journal: ACS medicinal chemistry letters 20120412

Title: Steven Harper , John A. McCauley , Michael T. Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor. ACS Med. Chem. Lett., 2012, 3 (4), pp 332-336

Title: Summa V, Ludmerer SW, McCauley JA, MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. Antimicrob Agents Chemother. 2012 Aug;56(8):4161-7.

Title: Qi Sun, et al. Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease. Signal Transduct Target Ther. 2021 May 29;6(1):212.

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Tags:1206524-86-8 Molecular Formula|1206524-86-8 MDL|1206524-86-8 SMILES|1206524-86-8 MK-5172 Potassium
Catalog No.: AA008TFE
1206524-86-8,MFCD25976701
1206524-86-8 | MK-5172 Potassium
Pack Size： 5mg
Purity： 99%
1 week
$222.00 $155.00
Pack Size： 10mg
Purity： 99%
1 week
$317.00 $222.00
Pack Size： 50mg
Purity： 99%
1 week
$908.00 $635.00
Pack Size： 100mg
Purity： 99%
1 week
$1,289.00 $902.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA008TFE
Chemical Name: MK-5172 Potassium
CAS Number: 1206524-86-8
Molecular Formula: C38H49KN6O9S
Molecular Weight: 804.9938
MDL Number: MFCD25976701
SMILES: C=CC1CC1(NC(=O)C1CC2CN1C(=O)C(NC(=O)OC1CC1CCCCCc1c(O2)nc2cc(OC)ccc2n1)C(C)(C)C)C(=O)[N-]S(=O)(=O)C1CC1.[K+]
Properties
Complexity: 1590  
Covalently-Bonded Unit Count: 2  
Defined Atom Stereocenter Count: 7  
Heavy Atom Count: 55  
Hydrogen Bond Acceptor Count: 12  
Hydrogen Bond Donor Count: 2  
Rotatable Bond Count: 8  
Literature fold

Title: Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor.

Journal: ACS medicinal chemistry letters20120412

Title: Steven Harper , John A. McCauley , Michael T. Discovery of MK-5172, a Macrocyclic Hepatitis C Virus NS3/4a Protease Inhibitor. ACS Med. Chem. Lett., 2012, 3 (4), pp 332-336

Title: Summa V, Ludmerer SW, McCauley JA, MK-5172, a selective inhibitor of hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants. Antimicrob Agents Chemother. 2012 Aug;56(8):4161-7.

Title: Qi Sun, et al. Bardoxolone and bardoxolone methyl, two Nrf2 activators in clinical trials, inhibit SARS-CoV-2 replication and its 3C-like protease. Signal Transduct Target Ther. 2021 May 29;6(1):212.

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