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1001409-50-2,MFCD18642668
Catalog No.:AA008TG2

1001409-50-2 | PDK1 inhibitor

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
95%
1 week  
$109.00   $76.00
- +
5mg
95%
1 week  
$183.00   $128.00
- +
50mg
99%
1 week  
$1,225.00   $858.00
- +
100mg
99%
1 week  
$1,955.00   $1,369.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008TG2
Chemical Name:
PDK1 inhibitor
CAS Number:
1001409-50-2
Molecular Formula:
C28H22F2N4O4
Molecular Weight:
516.4955
MDL Number:
MFCD18642668
SMILES:
O=C(c1cccn(c1=O)Cc1ccc(c(c1)F)F)NC(c1ccccc1)COc1ccc2c(c1)[nH]c(=O)[nH]2
Properties
Computed Properties
 
Complexity:
953  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Heavy Atom Count:
38  
Hydrogen Bond Acceptor Count:
6  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
8  
XLogP3:
4  

Literature

Title: Discovery of novel, potent, and selective inhibitors of 3-phosphoinositide-dependent kinase (PDK1).

Journal: Journal of medicinal chemistry 20111222

Title: Daniele S, et al. Dual Inhibition of PDK1 and Aurora Kinase A: An Effective Strategy to Induce Differentiation and Apoptosis of Human Glioblastoma Multiforme Stem Cells. ACS Chem Neurosci. 2017 Jan 18;8(1):100-114.

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SDS
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