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1196070-26-4,MFCD30207874
Catalog No.:AA008TJA

1196070-26-4 | GSK2190915 (sodiuM salt)

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
99%
1 week  
$290.00   $203.00
- +
10mg
99%
1 week  
$450.00   $315.00
- +
50mg
99%
1 week  
$1,289.00   $902.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008TJA
Chemical Name:
GSK2190915 (sodiuM salt)
CAS Number:
1196070-26-4
Molecular Formula:
C38H42N3NaO4S
Molecular Weight:
659.8126
MDL Number:
MFCD30207874
SMILES:
CCOc1ccc(cn1)c1ccc(cc1)Cn1c(CC(C(=O)[O-])(C)C)c(c2c1ccc(c2)OCc1ccc(cn1)C)SC(C)(C)C.[Na+]
Properties
Computed Properties
 
Complexity:
973  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
47  
Hydrogen Bond Acceptor Count:
7  
Rotatable Bond Count:
13  

Literature

Title: 5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor.

Journal: Journal of medicinal chemistry 20111208

Title: Stock NS, et al. 5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3--tert-butylsulfanyl-1--(6-ethoxypyridin-3-yl)benzyl-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor. J Med Chem. 2011 Dec 8;54(23):8013-29.

Title: Lorrain DS, et al. Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation. Eur J Pharmacol. 2010 Aug 25;640(1-3):211-8.

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Tags:1196070-26-4 Molecular Formula|1196070-26-4 MDL|1196070-26-4 SMILES|1196070-26-4 GSK2190915 (sodiuM salt)
Catalog No.: AA008TJA
1196070-26-4,MFCD30207874
1196070-26-4 | GSK2190915 (sodiuM salt)
Pack Size： 5mg
Purity： 99%
1 week
$290.00 $203.00
Pack Size： 10mg
Purity： 99%
1 week
$450.00 $315.00
Pack Size： 50mg
Purity： 99%
1 week
$1,289.00 $902.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA008TJA
Chemical Name: GSK2190915 (sodiuM salt)
CAS Number: 1196070-26-4
Molecular Formula: C38H42N3NaO4S
Molecular Weight: 659.8126
MDL Number: MFCD30207874
SMILES: CCOc1ccc(cn1)c1ccc(cc1)Cn1c(CC(C(=O)[O-])(C)C)c(c2c1ccc(c2)OCc1ccc(cn1)C)SC(C)(C)C.[Na+]
Properties
Complexity: 973  
Covalently-Bonded Unit Count: 2  
Heavy Atom Count: 47  
Hydrogen Bond Acceptor Count: 7  
Rotatable Bond Count: 13  
Literature fold

Title: 5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3-[3-tert-butylsulfanyl-1-[4-(6-ethoxypyridin-3-yl)benzyl]-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl]-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor.

Journal: Journal of medicinal chemistry20111208

Title: Stock NS, et al. 5-Lipoxygenase-activating protein (FLAP) inhibitors. Part 4: development of 3--tert-butylsulfanyl-1--(6-ethoxypyridin-3-yl)benzyl-5-(5-methylpyridin-2-ylmethoxy)-1H-indol-2-yl-2,2-dimethylpropionic acid (AM803), a potent, oral, once daily FLAP inhibitor. J Med Chem. 2011 Dec 8;54(23):8013-29.

Title: Lorrain DS, et al. Pharmacology of AM803, a novel selective five-lipoxygenase-activating protein (FLAP) inhibitor in rodent models of acute inflammation. Eur J Pharmacol. 2010 Aug 25;640(1-3):211-8.

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