107534-93-0,MFCD09953803
Catalog No.:AA008TJP

107534-93-0 | Anwulignan

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
98% by HPLC
in stock  
$89.00   $62.00
- +
100mg
10mM in DMSO
in stock  
$5,207.00   $3,645.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
Technical Information
Catalog Number:
AA008TJP
Chemical Name:
Anwulignan
CAS Number:
107534-93-0
Molecular Formula:
C20H24O4
Molecular Weight:
328.4022
MDL Number:
MFCD09953803
SMILES:
COc1cc(ccc1O)C[C@@H]([C@@H](Cc1ccc2c(c1)OCO2)C)C
Properties
Computed Properties
 
Complexity:
388  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Defined Bond Stereocenter Count:
0  
Formal Charge:
0  
Heavy Atom Count:
24  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
1  
Isotope Atom Count:
0  
Rotatable Bond Count:
6  
Undefined Atom Stereocenter Count:
0  
Undefined Bond Stereocenter Count:
0  
XLogP3:
5.2  

Literature

Title: Macelignan inhibits histamine release and inflammatory mediator production in activated rat basophilic leukemia mast cells.

Journal: Inflammation 20121001

Title: Effects of macelignan isolated from Myristica fragrans (Nutmeg) on expression of matrix metalloproteinase-1 and type I procollagen in UVB-irradiated human skin fibroblasts.

Journal: Biological & pharmaceutical bulletin 20120101

Title: Macelignan inhibits melanosome transfer mediated by protease-activated receptor-2 in keratinocytes.

Journal: Biological & pharmaceutical bulletin 20110101

Title: Determination of macelignan in rat plasma by high-performance liquid chromatography with ultraviolet detection.

Journal: Archives of pharmacal research 20080701

Title: Inhibitory effects of macelignan isolated from Myristica fragrans HOUTT. on melanin biosynthesis.

Journal: Biological & pharmaceutical bulletin 20080501

Title: Structure and estrogenic activity of new lignans from Iryanthera lancifolia.

Journal: Bioorganic & medicinal chemistry 20080315

Title: In vitro anti-biofilm activity of macelignan isolated from Myristica fragrans Houtt. against oral primary colonizer bacteria.

Journal: Phytotherapy research : PTR 20080301

Title: Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.

Journal: Diabetes 20080301

Title: Protective Effects of macelignan on cisplatin-induced hepatotoxicity is associated with JNK activation.

Journal: Biological & pharmaceutical bulletin 20080201

Title: Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds.

Journal: Bioorganic & medicinal chemistry letters 20080101

Title: Macelignan protects HepG2 cells against tert-butylhydroperoxide-induced oxidative damage.

Journal: BioFactors (Oxford, England) 20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology 20060501

Title: Anticariogenic activity of macelignan isolated from Myristica fragrans (nutmeg) against Streptococcus mutans.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology 20060301

Title: Anti-oxidant and anti-inflammatory activities of macelignan in murine hippocampal cell line and primary culture of rat microglial cells.

Journal: Biochemical and biophysical research communications 20050617

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SDS
Tags:107534-93-0 Molecular Formula|107534-93-0 MDL|107534-93-0 SMILES|107534-93-0 Anwulignan
Catalog No.: AA008TJP
107534-93-0,MFCD09953803
107534-93-0 | Anwulignan
Pack Size: 1mg
Purity: 98% by HPLC
in stock
$89.00 $62.00
Pack Size: 100mg
Purity: 10mM in DMSO
in stock
$5,207.00 $3,645.00
Quantity
- +
Add to Card
Order Now
bulk Quotation Request
Technical Information
Catalog Number: AA008TJP
Chemical Name: Anwulignan
CAS Number: 107534-93-0
Molecular Formula: C20H24O4
Molecular Weight: 328.4022
MDL Number: MFCD09953803
SMILES: COc1cc(ccc1O)C[C@@H]([C@@H](Cc1ccc2c(c1)OCO2)C)C
Properties
Complexity: 388  
Covalently-Bonded Unit Count: 1  
Defined Atom Stereocenter Count: 2  
Defined Bond Stereocenter Count: 0  
Formal Charge: 0  
Heavy Atom Count: 24  
Hydrogen Bond Acceptor Count: 4  
Hydrogen Bond Donor Count: 1  
Isotope Atom Count: 0  
Rotatable Bond Count: 6  
Undefined Atom Stereocenter Count: 0  
Undefined Bond Stereocenter Count: 0  
XLogP3: 5.2  
Literature fold

Title: Macelignan inhibits histamine release and inflammatory mediator production in activated rat basophilic leukemia mast cells.

Journal: Inflammation20121001

Title: Effects of macelignan isolated from Myristica fragrans (Nutmeg) on expression of matrix metalloproteinase-1 and type I procollagen in UVB-irradiated human skin fibroblasts.

Journal: Biological & pharmaceutical bulletin20120101

Title: Macelignan inhibits melanosome transfer mediated by protease-activated receptor-2 in keratinocytes.

Journal: Biological & pharmaceutical bulletin20110101

Title: Determination of macelignan in rat plasma by high-performance liquid chromatography with ultraviolet detection.

Journal: Archives of pharmacal research20080701

Title: Inhibitory effects of macelignan isolated from Myristica fragrans HOUTT. on melanin biosynthesis.

Journal: Biological & pharmaceutical bulletin20080501

Title: Structure and estrogenic activity of new lignans from Iryanthera lancifolia.

Journal: Bioorganic & medicinal chemistry20080315

Title: In vitro anti-biofilm activity of macelignan isolated from Myristica fragrans Houtt. against oral primary colonizer bacteria.

Journal: Phytotherapy research : PTR20080301

Title: Therapeutic potential of peroxisome proliferators--activated receptor-alpha/gamma dual agonist with alleviation of endoplasmic reticulum stress for the treatment of diabetes.

Journal: Diabetes20080301

Title: Protective Effects of macelignan on cisplatin-induced hepatotoxicity is associated with JNK activation.

Journal: Biological & pharmaceutical bulletin20080201

Title: Low-density lipoprotein (LDL)-antioxidant lignans from Myristica fragrans seeds.

Journal: Bioorganic & medicinal chemistry letters20080101

Title: Macelignan protects HepG2 cells against tert-butylhydroperoxide-induced oxidative damage.

Journal: BioFactors (Oxford, England)20070101

Title: Microsphere-based protease assays and screening application for lethal factor and factor Xa.

Journal: Cytometry. Part A : the journal of the International Society for Analytical Cytology20060501

Title: Anticariogenic activity of macelignan isolated from Myristica fragrans (nutmeg) against Streptococcus mutans.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology20060301

Title: Anti-oxidant and anti-inflammatory activities of macelignan in murine hippocampal cell line and primary culture of rat microglial cells.

Journal: Biochemical and biophysical research communications20050617

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