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1201913-82-7,MFCD27665464
Catalog No.:AA008TKH

1201913-82-7 | Tofogliflozin hydrate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$46.00   $32.00
- +
5mg
≥95%
in stock  
$199.00   $139.00
- +
10mg
≥95%
in stock  
$329.00   $230.00
- +
25mg
≥95%
in stock  
$600.00   $420.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008TKH
Chemical Name:
Tofogliflozin hydrate
CAS Number:
1201913-82-7
Molecular Formula:
C22H28O7
Molecular Weight:
404.4535
MDL Number:
MFCD27665464
SMILES:
OC[C@H]1O[C@]2(OCc3c2cc(cc3)Cc2ccc(cc2)CC)[C@@H]([C@H]([C@@H]1O)O)O.O
Properties
Computed Properties
 
Complexity:
521  
Covalently-Bonded Unit Count:
2  
Defined Atom Stereocenter Count:
5  
Heavy Atom Count:
29  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
4  

Literature

Title: Tofogliflozin: first global approval.

Journal: Drugs 20140601

Title: Discovery of tofogliflozin, a novel C-arylglucoside with an O-spiroketal ring system, as a highly selective sodium glucose cotransporter 2 (SGLT2) inhibitor for the treatment of type 2 diabetes.

Journal: Journal of medicinal chemistry 20120913

Title: Tofogliflozin, a potent and highly specific sodium/glucose cotransporter 2 inhibitor, improves glycemic control in diabetic rats and mice.

Journal: The Journal of pharmacology and experimental therapeutics 20120601

Title: [Research progress of sodium-glucose co-transporter 2 inhibitors for treatment of type 2 diabetes].

Journal: Yao xue xue bao = Acta pharmaceutica Sinica 20120601

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