Home Other Building Blocks 1061318-81-7
1061318-81-7,MFCD18633209
Catalog No.:AA008TLW

1061318-81-7 | Debio 0932 ,CUDC-305

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$82.00   $57.00
- +
5mg
99% (HPLC)
in stock  
$270.00   $189.00
- +
10mg
99% (HPLC)
in stock  
$412.00   $288.00
- +
25mg
99% (HPLC)
in stock  
$800.00   $560.00
- +
50mg
99% (HPLC)
in stock  
$1,318.00   $923.00
- +
100mg
99% (HPLC)
in stock  
$2,234.00   $1,564.00
- +
500mg
99% (HPLC)
in stock  
$7,073.00   $4,951.00
- +
1000mg
99% (HPLC)
in stock  
$11,279.00   $7,896.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008TLW
Chemical Name:
Debio 0932 ,CUDC-305
CAS Number:
1061318-81-7
Molecular Formula:
C22H30N6O2S
Molecular Weight:
442.5776
MDL Number:
MFCD18633209
SMILES:
CN(c1cc2OCOc2cc1Sc1nc2c(n1CCNCC(C)(C)C)ccnc2N)C
Properties
Computed Properties
 
Complexity:
591  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
31  
Hydrogen Bond Acceptor Count:
8  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
8  
XLogP3:
3.6  

Literature

Title: Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non-small cell lung cancer.

Journal: Molecular cancer therapeutics 20091201

Title: Bao R, et al. CUDC-305, a novel synthetic HSP90 inhibitor with unique pharmacologic properties for cancer therapy. Clin Cancer Res. 2009 Jun 15;15(12):4046-57.

Title: Stenderup K, et al. Debio 0932, a new oral Hsp90 inhibitor, alleviates psoriasis in a xenograft transplantation model. Acta Derm Venereol. 2014 Nov;94(6):672-6.

Title: Bao R, et al. Targeting heat shock protein 90 with CUDC-305 overcomes erlotinib resistance in non-small cell lung cancer. Mol Cancer Ther. 2009 Dec;8(12):3296-306.

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SDS
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Tags:1061318-81-7 Molecular Formula|1061318-81-7 MDL|1061318-81-7 SMILES|1061318-81-7 Debio 0932 ,CUDC-305