Home Other Building Blocks 1135242-13-5
1135242-13-5,MFCD17215959
Catalog No.:AA008TMX

1135242-13-5 | VU 0357017 Hydrochloride

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
in stock  
$23.00   $16.00
- +
10mg
98%
in stock  
$33.00   $23.00
- +
25mg
98%
in stock  
$55.00   $39.00
- +
50mg
98%
in stock  
$92.00   $64.00
- +
100mg
98%
in stock  
$154.00   $108.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008TMX
Chemical Name:
VU 0357017 Hydrochloride
CAS Number:
1135242-13-5
Molecular Formula:
C18H28ClN3O3
Molecular Weight:
369.8862
MDL Number:
MFCD17215959
SMILES:
CCOC(=O)N1CCC(CC1)NCCNC(=O)c1ccccc1C.Cl
Properties
Computed Properties
 
Complexity:
408  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
25  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
3  
Rotatable Bond Count:
7  

Literature

Title: Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience 20120620

Title: Digby GJ, et al. Chemical modification of the M(1) agonist VU0364572 reveals molecular switches in pharmacology and a bitopic binding mode. ACS Chem Neurosci. 2012 Dec 19;3(12):1025-36.

Title: Lebois EP, et al. Discovery and characterization of novel subtype-selective allosteric agonists for the investigation of M(1) receptor function in the central nervous system. ACS Chem Neurosci. 2010;1(2):104-121.

Title: Digby GJ, et al. Novel allosteric agonists of M1 muscarinic acetylcholine receptors induce brain region-specific responses that correspond with behavioral effects in animal models. J Neurosci. 2012 Jun 20;32(25):8532-44.

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SDS
Tags:1135242-13-5 Molecular Formula|1135242-13-5 MDL|1135242-13-5 SMILES|1135242-13-5 VU 0357017 Hydrochloride