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10351-88-9,MFCD17166965
Catalog No.:AA008WF4

10351-88-9 | Phyllanthin

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Purity
Availability
Price(USD)
Quantity
  
1mg
≥98%
in stock  
$72.00   $50.00
- +
5mg
≥98%
in stock  
$306.00   $214.00
- +
10mg
≥98%
in stock  
$522.00   $365.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008WF4
Chemical Name:
Phyllanthin
CAS Number:
10351-88-9
Molecular Formula:
C24H34O6
Molecular Weight:
418.5232
MDL Number:
MFCD17166965
SMILES:
COC[C@H]([C@H](Cc1ccc(c(c1)OC)OC)COC)Cc1ccc(c(c1)OC)OC
NSC Number:
619043
Properties
Computed Properties
 
Complexity:
407  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
2  
Heavy Atom Count:
30  
Hydrogen Bond Acceptor Count:
6  
Rotatable Bond Count:
13  
XLogP3:
4.2  

Literature

Title: Hepatoprotective activity of Indian Phyllanthus.

Journal: Pharmaceutical biology 20120801

Title: Endothelium-independent effects of phyllanthin and hypophyllanthin on vascular tension.

Journal: Fitoterapia 20111201

Title: Inhibitory effects of Phyllanthus amarus and its major lignans on human microsomal cytochrome P450 activities: evidence for CYP3A4 mechanism-based inhibition.

Journal: Drug metabolism and pharmacokinetics 20110101

Title: Protective activity of phyllanthin in ethanol-treated primary culture of rat hepatocytes.

Journal: Journal of ethnopharmacology 20100302

Title: Isolation, characterization and antioxidative effect of phyllanthin against CCl4-induced toxicity in HepG2 cell line.

Journal: Chemico-biological interactions 20091030

Title: Chromium-induced changes in ultramorphology and secondary metabolites of Phyllanthus amarus Schum & Thonn. - an hepatoprotective plant.

Journal: Environmental monitoring and assessment 20081201

Title: Recent advances in plant hepatoprotectives: a chemical and biological profile of some important leads.

Journal: Medicinal research reviews 20080901

Title: Quantitative determination of phyllanthin and hypophyllanthin in Phyllanthus species by high-performance thin layer chromatography.

Journal: Phytochemical analysis : PCA 20060101

Title: Hanh ND, et al. Physicochemical characterization of phyllanthin from Phyllanthus amarus Schum. et Thonn. Drug Dev Ind Pharm. 2014 Jun;40(6):793-802.

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