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1110766-97-6,MFCD28502075
Catalog No.:AA008ZS5

1110766-97-6 | (S,E)-3-(2,6-Dichloro-4-((4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-yl)carbamoyl)phenyl)-2-methylacrylic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
97%
in stock  
$17.00   $12.00
- +
2mg
97%
in stock  
$24.00   $17.00
- +
10mg
97%
in stock  
$62.00   $43.00
- +
  • Technical Information
  • Properties
  • Literature
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  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA008ZS5
Chemical Name:
(S,E)-3-(2,6-Dichloro-4-((4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-yl)carbamoyl)phenyl)-2-methylacrylic acid
CAS Number:
1110766-97-6
Molecular Formula:
C29H32Cl2N2O5S
Molecular Weight:
591.5458
MDL Number:
MFCD28502075
SMILES:
CCCCCCO[C@H](c1cccc(c1OC)c1csc(n1)NC(=O)c1cc(Cl)c(c(c1)Cl)/C=C(/C(=O)O)\C)C
Properties
Computed Properties
 
Complexity:
822  
Covalently-Bonded Unit Count:
1  
Defined Atom Stereocenter Count:
1  
Defined Bond Stereocenter Count:
1  
Heavy Atom Count:
39  
Hydrogen Bond Acceptor Count:
7  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
13  
XLogP3:
7.7  

Literature

Title: Development of a new knock-in mouse model and evaluation of pharmacological activities of lusutrombopag, a novel, nonpeptidyl small-molecule agonist of the human thrombopoietin receptor c-Mpl.

Journal: Experimental hematology 20180301

Title: Efficacy of Repeated Lusutrombopag Administration for Thrombocytopenia in a Patient Scheduled for Invasive Hepatocellular Carcinoma Treatment.

Journal: Internal medicine (Tokyo, Japan) 20171101

Title: Lusutrombopag increases hematocytes in a compensated liver cirrhosis patient.

Journal: Clinical journal of gastroenterology 20170101

Title: [Avoidance of platelet transfusion with readministration of lusutrombopag before radiofrequency ablation in hepatocellular carcinoma:a case report].

Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology 20170101

Title: Lusutrombopag: First Global Approval.

Journal: Drugs 20160101

Title: Kim ES, et al. Lusutrombopag: First Global Approval. Drugs. 2016 Jan;76(1):155-8.

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SDS
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Tags:1110766-97-6 Molecular Formula|1110766-97-6 MDL|1110766-97-6 SMILES|1110766-97-6 (S,E)-3-(2,6-Dichloro-4-((4-(3-(1-(hexyloxy)ethyl)-2-methoxyphenyl)thiazol-2-yl)carbamoyl)phenyl)-2-methylacrylic acid