Home Other Building Blocks 1113-60-6
1113-60-6,MFCD00083380
Catalog No.:AA00921O

1113-60-6 | -Hydroxypyruvic acid

Pack Size
Purity
Availability
Price(USD)
Quantity
  
1mg
≥95%
in stock  
$236.00   $165.00
- +
5mg
≥95%
in stock  
$691.00   $484.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA00921O
Chemical Name:
-Hydroxypyruvic acid
CAS Number:
1113-60-6
Molecular Formula:
C3H4O4
Molecular Weight:
104.0615
MDL Number:
MFCD00083380
SMILES:
OCC(=O)C(=O)O
FEMA Number:
3843
Properties
Computed Properties
 
Complexity:
95.1  
Covalently-Bonded Unit Count:
1  
Heavy Atom Count:
7  
Hydrogen Bond Acceptor Count:
4  
Hydrogen Bond Donor Count:
2  
Rotatable Bond Count:
2  
XLogP3:
-1  

Literature

Title: A pH-based high-throughput assay for transketolase: fingerprinting of substrate tolerance and quantitative kinetics.

Journal: Chembiochem : a European journal of chemical biology 20121015

Title: Glyoxylate carboligase: a unique thiamin diphosphate-dependent enzyme that can cycle between the 4'-aminopyrimidinium and 1',4'-iminopyrimidine tautomeric forms in the absence of the conserved glutamate.

Journal: Biochemistry 20121009

Title: Enhancement of the substrate scope of transketolase.

Journal: Chembiochem : a European journal of chemical biology 20120903

Title: Investigating the reaction mechanism and organocatalytic synthesis of α,α'-dihydroxy ketones.

Journal: Organic & biomolecular chemistry 20120407

Title: Two alanine aminotranferases link mitochondrial glycolate oxidation to the major photorespiratory pathway in Arabidopsis and rice.

Journal: Journal of experimental botany 20120401

Title: S-Nitrosylated proteins in pea (Pisum sativum L.) leaf peroxisomes: changes under abiotic stress.

Journal: Journal of experimental botany 20120301

Title: Multiple strategies to prevent oxidative stress in Arabidopsis plants lacking the malate valve enzyme NADP-malate dehydrogenase.

Journal: Journal of experimental botany 20120201

Title: [Analysis of the binding domain of hydroxypyruvate isomerase homologues in hypertrophic scar fibroblasts].

Journal: Zhonghua shao shang za zhi = Zhonghua shaoshang zazhi = Chinese journal of burns 20120201

Title: Combined inactivation of the Clostridium cellulolyticum lactate and malate dehydrogenase genes substantially increases ethanol yield from cellulose and switchgrass fermentations.

Journal: Biotechnology for biofuels 20120101

Title: Molecular modelling, docking and interaction studies of human-plasmogen and salmonella enolase with enolase inhibitors.

Journal: Bioinformation 20120101

Title: Complete genome sequence, lifestyle, and multi-drug resistance of the human pathogen Corynebacterium resistens DSM 45100 isolated from blood samples of a leukemia patient.

Journal: BMC genomics 20120101

Title: Transgenic Introduction of a Glycolate Oxidative Cycle into A. thaliana Chloroplasts Leads to Growth Improvement.

Journal: Frontiers in plant science 20120101

Title: Transport proteins regulate the flux of metabolites and cofactors across the membrane of plant peroxisomes.

Journal: Frontiers in plant science 20120101

Title: NADP-dependent isocitrate dehydrogenase from Arabidopsis roots contributes in the mechanism of defence against the nitro-oxidative stress induced by salinity.

Journal: TheScientificWorldJournal 20120101

Title: Design and evaluation of novel primers for the detection of genes encoding diverse enzymes of methylotrophy and autotrophy.

Journal: Polish journal of microbiology 20120101

Title: Novel fungal phenylpyruvate reductase belongs to d-isomer-specific 2-hydroxyacid dehydrogenase family.

Journal: Biochimica et biophysica acta 20111201

Title: Structural and biochemical characterization of the C₃-C₄ intermediate Brassica gravinae and relatives, with particular reference to cellular distribution of Rubisco.

Journal: Journal of experimental botany 20111101

Title: Immobilised enzyme microreactor for screening of multi-step bioconversions: characterisation of a de novo transketolase-ω-transaminase pathway to synthesise chiral amino alcohols.

Journal: Journal of biotechnology 20110920

Title: Evolution of enzymes involved in the photorespiratory 2-phosphoglycolate cycle from cyanobacteria via algae toward plants.

Journal: Photosynthesis research 20110901

Title: Peroxisomal hydroxypyruvate reductase is not essential for photorespiration in Arabidopsis but its absence causes an increase in the stoichiometry of photorespiratory CO2 release.

Journal: Photosynthesis research 20110901

Title: Diastereoselective self-condensation of dihydroxyfumaric acid in water: potential route to sugars.

Journal: Angewandte Chemie (International ed. in English) 20110822

Title: Plasmid construction for genetic modification of dicotyledonous plants with a glycolate oxidizing pathway.

Journal: Genetics and molecular research : GMR 20110706

Title: Facultative methylotrophs from the human oral cavity and methylotrophy in strains of Gordonia, Leifsonia, and Microbacterium.

Journal: Archives of microbiology 20110601

Title: Cytotoxic molecular mechanisms and cytoprotection by enzymic metabolism or autoxidation for glyceraldehyde, hydroxypyruvate and glycolaldehyde.

Journal: Chemico-biological interactions 20110530

Title: Studies on a unique organelle localization of a liver enzyme, serine:pyruvate (or alanine:glyoxylate) aminotransferase.

Journal: Proceedings of the Japan Academy. Series B, Physical and biological sciences 20110511

Title: The Plant Organelles Database 2 (PODB2): an updated resource containing movie data of plant organelle dynamics.

Journal: Plant & cell physiology 20110201

Title: The hydroxypyruvate-reducing system in Arabidopsis: multiple enzymes for the same end.

Journal: Plant physiology 20110201

Title: Tartronate semialdehyde reductase defines a novel rate-limiting step in assimilation and bioconversion of glycerol in Ustilago maydis.

Journal: PloS one 20110101

Title: Evolution of exon-intron structure and alternative splicing.

Journal: PloS one 20110101

Title: Primary hyperoxaluria.

Journal: International journal of nephrology 20110101

Title: Neuroprotective peptide ADNF-9 in fetal brain of C57BL/6 mice exposed prenatally to alcohol.

Journal: Journal of biomedical science 20110101

Title: The evolution of metabolic networks of E. coli.

Journal: BMC systems biology 20110101

Title: An engineered pathway for glyoxylate metabolism in tobacco plants aimed to avoid the release of ammonia in photorespiration.

Journal: BMC biotechnology 20110101

Title: Defining the plant peroxisomal proteome: from Arabidopsis to rice.

Journal: Frontiers in plant science 20110101

Title: Potential cytotoxic effect of hydroxypyruvate produced from D-serine by astroglial D-amino acid oxidase.

Journal: Journal of biochemistry 20101201

Title: Structural insights into substrate specificity in variants of N-acetylneuraminic Acid lyase produced by directed evolution.

Journal: Journal of molecular biology 20101119

Title: Mitochondrial malate dehydrogenase lowers leaf respiration and alters photorespiration and plant growth in Arabidopsis.

Journal: Plant physiology 20101101

Title: Beyond the dopamine receptor: novel therapeutic targets for treating schizophrenia.

Journal: Dialogues in clinical neuroscience 20100901

Title: Differential proteomic response to heat stress in thermal Agrostis scabra and heat-sensitive Agrostis stolonifera.

Journal: Physiologia plantarum 20100601

Title: Tricarboxylic acid cycle activity regulates tomato root growth via effects on secondary cell wall production.

Journal: Plant physiology 20100601

Title: Glyoxylate rather than ascorbate is an efficient precursor for oxalate biosynthesis in rice.

Journal: Journal of experimental botany 20100601

Title: Structure and substrate docking of a hydroxy(phenyl)pyruvate reductase from the higher plant Coleus blumei Benth.

Journal: Acta crystallographica. Section D, Biological crystallography 20100501

Title: Identification of the 2-hydroxyglutarate and isovaleryl-CoA dehydrogenases as alternative electron donors linking lysine catabolism to the electron transport chain of Arabidopsis mitochondria.

Journal: The Plant cell 20100501

Title: Fatty acid beta-oxidation in germinating Arabidopsis seeds is supported by peroxisomal hydroxypyruvate reductase when malate dehydrogenase is absent.

Journal: Plant molecular biology 20100101

Title: Design and characterization of a prototype enzyme microreactor: quantification of immobilized transketolase kinetics.

Journal: Biotechnology progress 20100101

Title: In silico feasibility of novel biodegradation pathways for 1,2,4-trichlorobenzene.

Journal: BMC systems biology 20100101

Title: Transcriptional profiling of an Fd-GOGAT1/GLU1 mutant in Arabidopsis thaliana reveals a multiple stress response and extensive reprogramming of the transcriptome.

Journal: BMC genomics 20100101

Title: Comparative analysis of proteome maps of silkworm hemolymph during different developmental stages.

Journal: Proteome science 20100101

Title: The Role of PPARα Activation in Liver and Muscle.

Journal: PPAR research 20100101

Title: Methanol assimilation in Methylobacterium extorquens AM1: demonstration of all enzymes and their regulation.

Journal: PloS one 20100101

Title: Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5'-phosphate synthesis.

Journal: Molecular systems biology 20100101

Title: Metabolism gets lucky.

Journal: Molecular systems biology 20100101

Title: A systems biology approach uncovers cellular strategies used by Methylobacterium extorquens AM1 during the switch from multi- to single-carbon growth.

Journal: PloS one 20100101

Title: Potential diagnostic biomarkers in serum of idiopathic pulmonary arterial hypertension.

Journal: Respiratory medicine 20091201

Title: Halogenated pyruvate derivatives as substrates of transketolase from Saccharomyces cerevisiae.

Journal: Biochemistry. Biokhimiia 20091101

Title: Role of plant glyoxylate reductases during stress: a hypothesis.

Journal: The Biochemical journal 20091001

Title: Assay of alanine:glyoxylate aminotransferase in human liver by its serine: glyoxylate aminotransferase activity.

Journal: Biomedical research (Tokyo, Japan) 20091001

Title: X-ray crystal structure of GarR-tartronate semialdehyde reductase from Salmonella typhimurium.

Journal: Journal of structural and functional genomics 20090901

Title: Low concentration of anti-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene induces alterations of extracellular protein profile of exposed epithelial cells.

Journal: Proteomics 20090901

Title: Detection of a gem-diamine and a stable quinonoid intermediate in the reaction catalyzed by serine-glyoxylate aminotransferase from Hyphomicrobium methylovorum.

Journal: Biochimica et biophysica acta 20090601

Title: Efficient reconstruction of metabolic pathways by bidirectional chemical search.

Journal: Bulletin of mathematical biology 20090401

Title: Influence of Honey on the Suppression of Human Low Density Lipoprotein (LDL) Peroxidation (In vitro).

Journal: Evidence-based complementary and alternative medicine : eCAM 20090301

Title: Subcellular localization and enzymatic properties of differentially expressed transketolase genes isolated from the desiccation tolerant resurrection plant Craterostigma plantagineum.

Journal: Planta 20090201

Title: Exploring and dissecting genome-wide gene expression responses of Penicillium chrysogenum to phenylacetic acid consumption and penicillinG production.

Journal: BMC genomics 20090101

Title: Methylobacterium genome sequences: a reference blueprint to investigate microbial metabolism of C1 compounds from natural and industrial sources.

Journal: PloS one 20090101

Title: Shoot-specific down-regulation of protein farnesyltransferase (alpha-subunit) for yield protection against drought in canola.

Journal: Molecular plant 20090101

Title: Parallel expression evolution of oxidative stress-related genes in fiber from wild and domesticated diploid and polyploid cotton (Gossypium).

Journal: BMC genomics 20090101

Title: Conserved main-chain peptide distortions: a proposed role for Ile203 in catalysis by dihydrodipicolinate synthase.

Journal: Protein science : a publication of the Protein Society 20081201

Title: Peroxisomal malate dehydrogenase is not essential for photorespiration in Arabidopsis but its absence causes an increase in the stoichiometry of photorespiratory CO2 release.

Journal: Plant physiology 20081001

Title: A cytosolic pathway for the conversion of hydroxypyruvate to glycerate during photorespiration in Arabidopsis.

Journal: The Plant cell 20081001

Title: Structural analysis of substrate and effector binding in Mycobacterium tuberculosis D-3-phosphoglycerate dehydrogenase.

Journal: Biochemistry 20080812

Title: Identification and functional analysis of light-responsive unique genes and gene family members in rice.

Journal: PLoS genetics 20080801

Title: Molecular cloning and characterization of Plasmodium falciparum transketolase.

Journal: Molecular and biochemical parasitology 20080701

Title: Identification and characterization of a plastid-localized Arabidopsis glyoxylate reductase isoform: comparison with a cytosolic isoform and implications for cellular redox homeostasis and aldehyde detoxification.

Journal: Journal of experimental botany 20080601

Title: Gamma-hydroxybutyrate accumulation in Arabidopsis and tobacco plants is a general response to abiotic stress: putative regulation by redox balance and glyoxylate reductase isoforms.

Journal: Journal of experimental botany 20080601

Title: Metabolism of halophilic archaea.

Journal: Extremophiles : life under extreme conditions 20080301

Title: Properties of serine:glyoxylate aminotransferase purified from Arabidopsis thaliana leaves.

Journal: Acta biochimica et biophysica Sinica 20080201

Title: Evolutionary analysis of the TPP-dependent enzyme family.

Journal: Journal of molecular evolution 20080101

Title: A model for carbohydrate metabolism in the diatom Phaeodactylum tricornutum deduced from comparative whole genome analysis.

Journal: PloS one 20080101

Title: Metaproteomics provides functional insight into activated sludge wastewater treatment.

Journal: PloS one 20080101

Title: Time-resolved metabolomics reveals metabolic modulation in rice foliage.

Journal: BMC systems biology 20080101

Title: Complete genome sequence of the extremely acidophilic methanotroph isolate V4, Methylacidiphilum infernorum, a representative of the bacterial phylum Verrucomicrobia.

Journal: Biology direct 20080101

Title: Development of a broad-host-range sacB-based vector for unmarked allelic exchange.

Journal: BMC research notes 20080101

Title: Whole genome transcriptome polymorphisms in Arabidopsis thaliana.

Journal: Genome biology 20080101

Title: Over-expression of a hydroxypyruvate reductase in Methylobacterium sp. MB200 enhances glyoxylate accumulation.

Journal: Journal of industrial microbiology & biotechnology 20071001

Title: Directed evolution of transketolase activity on non-phosphorylated substrates.

Journal: Journal of biotechnology 20070930

Title: Identification of a novel glyoxylate reductase supports phylogeny-based enzymatic substrate specificity prediction.

Journal: Biochimica et biophysica acta 20070901

Title: Oxalate synthesis from hydroxypyruvate in vitamin-B6-deficient rats.

Journal: Urological research 20070801

Title: Chloroplastic photorespiratory bypass increases photosynthesis and biomass production in Arabidopsis thaliana.

Journal: Nature biotechnology 20070501

Title: Simultaneous measurement of D-serine dehydratase and d-amino acid oxidase activities by the detection of 2-oxo-acid formation with reverse-phase high-performance liquid chromatography.

Journal: Analytical biochemistry 20070301

Title: One-pot synthesis of amino-alcohols using a de-novo transketolase and beta-alanine: pyruvate transaminase pathway in Escherichia coli.

Journal: Biotechnology and bioengineering 20070215

Title: The ORF YNL274c (GOR1) codes for glyoxylate reductase in Saccharomyces cerevisiae.

Journal: Yeast (Chichester, England) 20070201

Title: Which stage of the process of apotransketolase interaction with thiamine diphosphate is affected by the regulatory activity of the donor substrate?

Journal: IUBMB life 20070201

Title: Influence of donor substrate on kinetic parameters of thiamine diphosphate binding to transketolase.

Journal: Biochemistry. Biokhimiia 20070101

Title: Modeling Neisseria meningitidis metabolism: from genome to metabolic fluxes.

Journal: Genome biology 20070101

Title: Glycerate kinase of the hyperthermophilic archaeon Thermoproteus tenax: new insights into the phylogenetic distribution and physiological role of members of the three different glycerate kinase classes.

Journal: BMC genomics 20070101

Title: Synthesis with good enantiomeric excess of both enantiomers of alpha-ketols and acetolactates by two thiamin diphosphate-dependent decarboxylases.

Journal: Bioorganic chemistry 20061201

Title: Purification, crystallization and preliminary crystallographic studies on 2-dehydro-3-deoxygalactarate aldolase from Leptospira interrogans.

Journal: Acta crystallographica. Section F, Structural biology and crystallization communications 20061201

Title: On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of 'glycolate' units into ansamitocin and soraphen A.

Journal: Journal of the American Chemical Society 20061108

Title: The metabolic significance of octulose phosphates in the photosynthetic carbon reduction cycle in spinach.

Journal: Photosynthesis research 20061101

Title: Structural basis of substrate specificity in human glyoxylate reductase/hydroxypyruvate reductase.

Journal: Journal of molecular biology 20060630

Title: Restrictive cardiomyopathy in a patient with primary hyperoxaluria type II.

Journal: Clinical research in cardiology : official journal of the German Cardiac Society 20060401

Title: In-situ preparation of binary-phase silver nanoparticles at a high Ag+ concentration.

Journal: Journal of nanoscience and nanotechnology 20060301

Title: Enzymatic and mechanistic studies on the formation of N-phenylglycolohydroxamic acid from nitrosobenzene and pyruvate in spinach leaf homogenate.

Journal: Journal of agricultural and food chemistry 20060125

Title: A flexible representation of omic knowledge for thorough analysis of microarray data.

Journal: Plant methods 20060101

Title: Isolation of glyoxysomes from pumpkin cotyledons.

Journal: Current protocols in cell biology 20060101

Title: Reaction of serine-glyoxylate aminotransferase with the alternative substrate ketomalonate indicates rate-limiting protonation of a quinonoid intermediate.

Journal: Biochemistry 20051206

Title: A preliminary account of the properties of recombinant human Glyoxylate reductase (GRHPR), LDHA and LDHB with glyoxylate, and their potential roles in its metabolism.

Journal: Biochimica et biophysica acta 20051201

Title: Variation in the activity of some enzymes of photorespiratory metabolism in C4 grasses.

Journal: Annals of botany 20051001

Title: Monitoring the acetohydroxy acid synthase reaction and related carboligations by circular dichroism spectroscopy.

Journal: Analytical biochemistry 20050701

Title: Promoter rearrangements cause species-specific hepatic regulation of the glyoxylate reductase/hydroxypyruvate reductase gene by the peroxisome proliferator-activated receptor alpha.

Journal: The Journal of biological chemistry 20050624

Title: N-methyl-L-amino acid dehydrogenase from Pseudomonas putida. A novel member of an unusual NAD(P)-dependent oxidoreductase superfamily.

Journal: The FEBS journal 20050301

Title: D-Serine-induced nephrotoxicity: a HPLC-TOF/MS-based metabonomics approach.

Journal: Toxicology 20050214

Title: Suicide inhibition of acetohydroxyacid synthase by hydroxypyruvate.

Journal: Journal of enzyme inhibition and medicinal chemistry 20050201

Title: Complete reannotation of the Arabidopsis genome: methods, tools, protocols and the final release.

Journal: BMC biology 20050101

Title: Discovering disease-associated enzymes by proteome reactivity profiling.

Journal: Chemistry & biology 20041101

Title: Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath).

Journal: PLoS biology 20041001

Title: Molecular aetiology of primary hyperoxaluria and its implications for clinical management.

Journal: Expert reviews in molecular medicine 20040109

Title: [New thermophilic methanotrophs of the genus Methylocaldum].

Journal: Mikrobiologiia 20040101

Title: A sugar beet chlorophyll a/b binding protein promoter void of G-box like elements confers strong and leaf specific reporter gene expression in transgenic sugar beet.

Journal: BMC biotechnology 20040101

Title: Molecular and structural characterization of NADPH-dependent d-glycerate dehydrogenase from the enteric parasitic protist Entamoeba histolytica.

Journal: The Biochemical journal 20031101

Title: Attempts to inhibit ruminal methanogenesis by blocking pyruvate oxidative decarboxylation.

Journal: Canadian journal of microbiology 20031001

Title: Changes in some enzymes of microbodies and plastid development in excised radish cotyledons: effect of narciclasine.

Journal: Journal of plant physiology 20030901

Title: The P34 syringolide elicitor receptor interacts with a soybean photorespiration enzyme, NADH-dependent hydroxypyruvate reductase.

Journal: Molecular plant-microbe interactions : MPMI 20021201

Title: Proteomic analysis of leaf peroxisomal proteins in greening cotyledons of Arabidopsis thaliana.

Journal: Plant & cell physiology 20020701

Title: Novel mutation in the GRHPR gene in a Chinese patient with primary hyperoxaluria type 2 requiring renal transplantation from a living related donor.

Journal: American journal of kidney diseases : the official journal of the National Kidney Foundation 20011201

Title: Alternative oxidase in durum wheat mitochondria. Activation by pyruvate, hydroxypyruvate and glyoxylate and physiological role.

Journal: Plant & cell physiology 20011201

Title: A novel hyperthermophilic archaeal glyoxylate reductase from Thermococcus litoralis. Characterization, gene cloning, nucleotide sequence and expression in Escherichia coli.

Journal: European journal of biochemistry 20010901

Title: Alteration of the specificity of malate dehydrogenase by chemical modulation of an active site arginine.

Journal: The Journal of biological chemistry 20010817

Title: Primary hyperoxaluria type 2 without L-glycericaciduria: is the disease under-diagnosed?

Journal: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 20010801

Title: Cleaving of ketosubstrates by transketolase and the nature of the products formed.

Journal: Biochemistry. Biokhimiia 20010801

Title: Examination of donor substrate conversion in yeast transketolase.

Journal: The Journal of biological chemistry 20010511

Title: Initial velocity, spectral, and pH studies of the serine-glyoxylate aminotransferase from Hyphomicrobiuim methylovorum.

Journal: Archives of biochemistry and biophysics 20010415

Title: Biochemical characterization of the 2-ketoacid reductases encoded by ycdW and yiaE genes in Escherichia coli.

Journal: The Biochemical journal 20010315

Title: New developments in our understanding of the beta-hydroxyacid dehydrogenases.

Journal: Chemico-biological interactions 20010130

Title: [Alpha ketoglutarate dehydrogenase deficiency].

Journal: Ryoikibetsu shokogun shirizu 20010101

Title: Teerajetgul Y, et al. Oxalate synthesis from hydroxypyruvate in vitamin-B6-deficient rats.Urol Res. 2007 Aug;35(4):173-8. Epub 2007 Jun 13.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:1113-60-6 Molecular Formula|1113-60-6 MDL|1113-60-6 SMILES|1113-60-6 -Hydroxypyruvic acid