Name: Name:AM-211
Brand: AABLOCKS
SKU: AA0097SN
Rating: 90 (10 reviews)

Technical Information

Catalog Number: AA0097SN

Chemical Name: AM-211

CAS Number: 1175526-27-8

Molecular Formula: C27H27F3N2O4

Molecular Weight: 500.5095

MDL Number: MFCD22124468

SMILES: CCN(C(=O)NCc1ccccc1)Cc1cc(ccc1c1cc(ccc1OC)CC(=O)O)C(F)(F)F

Properties

Complexity: 714

Covalently-Bonded Unit Count: 1

Defined Atom Stereocenter Count: 0

Defined Bond Stereocenter Count: 0

Formal Charge: 0

Heavy Atom Count: 36

Hydrogen Bond Acceptor Count: 7

Hydrogen Bond Donor Count: 2

Isotope Atom Count: 0

Rotatable Bond Count: 9

Undefined Atom Stereocenter Count: 0

Undefined Bond Stereocenter Count: 0

XLogP3: 4.9

Literature fold

Title: Pharmacodynamics, pharmacokinetics, and safety of AM211: a novel and potent antagonist of the prostaglandin D2 receptor type 2.

Journal: Journal of clinical pharmacology20121001

Title: Pharmacology of AM211, a potent and selective prostaglandin D2 receptor type 2 antagonist that is active in animal models of allergic inflammation.

Journal: The Journal of pharmacology and experimental therapeutics20110701

Title: Bain G, et al. Pharmacology of AM211, a potent and selective prostaglandin D2 receptor type 2 antagonist that is active in animal models of allergic inflammation. J Pharmacol Exp Ther. 2011 Jul;338(1):290-301.

1175526-27-8 | AM-211