Home Carboxes 1431697-85-6
1431697-85-6,MFCD23380597
Catalog No.:AA009C6B

1431697-85-6 | AT-7519 trifluoroacetate

Pack Size
Purity
Availability
Price(USD)
Quantity
  
5mg
98%
1 week  
$146.00   $102.00
- +
10mg
98%
1 week  
$193.00   $135.00
- +
50mg
98%
1 week  
$352.00   $247.00
- +
100mg
98%
1 week  
$447.00   $313.00
- +
  • Technical Information
  • Properties
  • Literature
  • Request for Quotation
  • Download SDS
  • Technical Information
  • Properties
  • Literature
Technical Information
Catalog Number:
AA009C6B
Chemical Name:
AT-7519 trifluoroacetate
CAS Number:
1431697-85-6
Molecular Formula:
C18H18Cl2F3N5O4
Molecular Weight:
496.2678
MDL Number:
MFCD23380597
SMILES:
OC(=O)C(F)(F)F.O=C(c1[nH]ncc1NC(=O)c1c(Cl)cccc1Cl)NC1CCNCC1
Properties
Computed Properties
 
Complexity:
563  
Covalently-Bonded Unit Count:
2  
Heavy Atom Count:
32  
Hydrogen Bond Acceptor Count:
9  
Hydrogen Bond Donor Count:
5  
Rotatable Bond Count:
4  

Literature

Title: Santo L, et al. AT7519, A novel small molecule multi-cyclin-dependent kinase inhibitor, induces apoptosis in multiple myeloma via GSK-3beta activation and RNA polymerase II inhibition. Oncogene. 2010 Apr 22;29(16):2325-36.

Title: Squires MS, et al. Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines. Biological characterization of AT7519, a small-molecule inhibitor of cyclin-dependent kinases, in human tumor cell lines.

Title: Squires MS, et al. AT7519, a cyclin-dependent kinase inhibitor, exerts its effects by transcriptional inhibition in leukemia cell lines and patient samples. Mol Cancer Ther. 2010 Apr;9(4):920-8.

Quotation Request
Company Name:
*
Contact Person:
*
Email:
*
Quantity Required:
*
Country:
Additional Info:
SDS
Tags:1431697-85-6 Molecular Formula|1431697-85-6 MDL|1431697-85-6 SMILES|1431697-85-6 AT-7519 trifluoroacetate